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Question | Discussion | References

Updated August 19, 2011

World Health Organization (WHO) HIV Case Definitions and Staging Systems

Learning Objectives

A 27-year-old East African woman is newly diagnosed with HIV shortly after being diagnosed with pulmonary tuberculosis. Her CD4 count is 260 cells/mm³ (17%). Her past medical history is remarkable only for a prior case of presumed bacterial pneumonia that was successfully treated with antibiotics.

How would you stage this woman's HIV disease according to World Health Organization (WHO) criteria?

	Her clinical stage is Advanced HIV-associated symptoms (stage 3) and her immunologic stage is Severe HIV-associated Immunodeficiency.
	Her clinical stage is Severe HIV-associated Symptoms (stage 4) and her immunologic stage is Advanced HIV-associated Immunodeficiency.
	Her clinical stage is Advanced HIV-associated Symptoms (stage 3) and her immunologic stage is Advanced HIV-associated Immunodeficiency.
	Her clinical stage is Severe HIV-associated Symptoms (stage 4) and her immunologic stage is Severe HIV-associated Immunodeficiency.

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