Question | Discussion | References

Updated August 19, 2011

World Health Organization (WHO) HIV Case Definitions and Staging Systems

Author: Christopher Behrens, MD

A 27-year-old East African woman is newly diagnosed with HIV shortly after being diagnosed with pulmonary tuberculosis. Her CD4 count is 260 cells/mm3 (17%). Her past medical history is remarkable only for a prior case of presumed bacterial pneumonia that was successfully treated with antibiotics.

How would you stage this woman's HIV disease according to World Health Organization (WHO) criteria?

A Her clinical stage is Advanced HIV-associated symptoms (stage 3) and her immunologic stage is Severe HIV-associated Immunodeficiency.
B Her clinical stage is Severe HIV-associated Symptoms (stage 4) and her immunologic stage is Advanced HIV-associated Immunodeficiency.
C Her clinical stage is Advanced HIV-associated Symptoms (stage 3) and her immunologic stage is Advanced HIV-associated Immunodeficiency.
D Her clinical stage is Severe HIV-associated Symptoms (stage 4) and her immunologic stage is Severe HIV-associated Immunodeficiency.