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Early Infant Diagnosis of HIV

You answered:

B Perform a DNA or RNA PCR test on a dried bloodspot sample only after the infant has stopped breastfeeding. If the initial test is POSITIVE, have the infant return in 2 months for a repeat confirmatory sample.

This answer is incorrect. Although DNA or RNA based testing is the recommended method of diagnosing HIV infection in infants, this testing need not be delayed until breastfeeding has stopped. DNA or RNA-based testing is sensitive and specific in breastfeeding infants and can be performed at 4 to 6 weeks of age, regardless of the infant's feeding method.

Choose another answer:

A Perform a rapid HIV 1/2 antibody test (e.g. Determine or Unigold) on the baby at 4 to 6 weeks of age.
C Perform a DNA or RNA PCR test on a dried bloodspot sample at 4 to 6 weeks of age. If the initial test is POSITIVE, start the infant on anti-retroviral therapy immediately and collect a second blood sample for confirmatory HIV testing.
D Perform a DNA or RNA PCR test on a dried bloodspot sample at 4-6 weeks of age. If the initial test is POSITIVE, have the infant return in 2 months for confirmatory HIV testing.

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