Question | Discussion | References

Prevention of Mother to Child Transmission of HIV (PMTCT) during Antenatal Care

You answered:

A She should not be given efavirenz at any time during pregnancy given its risk of teratogenicity.

This answer is incorrect. The WHO currently endorses the use of efavirenz in pregnant women, including those who are in the first trimester of pregnancy. Programmatic experience with the use of efavirenz in pregnancy has not suggested a significantly elevated risk of birth defects, and efavirenz has fewer toxic effects in pregnancy than nevirapine.

Choose another answer:

B A Cesarean section should be planned at delivery in order to reduce the risk of HIV transmission to her infant.
C Nevirapine should be avoided unless this woman's CD4 count is known to be below 500 cells/mm3.
D She should start triple antiretroviral therapy immediately and a CD4 count should be checked if possible.

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