You and the UW Institute for Protein Design
Imagine taking the building blocks of life — proteins — and re-designing them to “fix” major problems in medicine, like cancer, or Alzheimer’s or the flu.
You can help our researchers do just that! By supporting the University of Washington’s Institute for Protein Design. Use the convenient giving form at right, or read more about protein design, below.
The Power of Proteins
“Looking at the range of things that proteins do in living systems gives you a hint of what proteins could do if you designed them to order.”
—David Baker, Ph.D., Director
UW Institute for Protein Design
Proteins are the body’s workhorses, responsible for everything from digesting food to building tissue. They do nearly every job, at every moment, within the body. When they malfunction, the result is disease or illness.
Drugs today are designed to fix malfunctions: to go into the body, to bind to ill-performing proteins, and to change the course of a disease. Many of these drugs, however, are derived from small molecules. This can limit their effectiveness and their precision when binding to proteins, which are much larger molecules.
Researchers at the Institute for Protein Design are working to create proteins that will bind more effectively and more precisely to malfunctioning proteins in the body. They’ve already developed proteins with new functions, including HIV vaccine candidates and flu inhibitors — and the sky, quite literally, is the limit.
At the UW Institute for Protein Design (IPD)
David Baker, Ph.D.
B.A., Harvard University (Physics)
Ph.D., University of California, Berkeley (Molecular and Cell Biology)
- Professor, Department of Biochemistry
- Adjunct Professor in the Department of Genome Sciences, Department of Bioengineering, Department of Physics, Department of Computer Science, Department of Chemical Engineering
Among many achievements and distinctions, Baker is a Howard Hughes Medical Institute investigator and has received the prestigious Sackler Prize in Biophysics.
Michelle Scalley-Kim, Ph.D.
Director of Strategy and Research
B.A., University of California, Berkeley (Molecular and Cell Biology)
Ph.D., University of Washington (Biochemistry)
MBA, University of Washington (Technology Management)
Department of Biochemistry
Scalley-Kim did her graduate work in Baker’s lab, where she studied protein folding and protein design. Before returning to UW Medicine, she led a protein engineering group at VLST, a Seattle-area biotech.
- UW Medicine faculty and trainees in biochemistry, genome sciences, biological structure, pharmacology, immunology, computational biology and more
- Personnel from computer and biotechnology industries
Your support will make a real difference at the UW Institute for Protein Design! Listed below are several ways that you can partner with the institute.
Your gift or grant will support research, education and infrastructure at the institute. Please give today by using the convenient giving form at right.
Become a UW Medicine Corporate Partner
UW Medicine benefits from partnering with organizations that share our commitment to health. Learn more about investing with UW Medicine, and become our Corporate Partner.
Play With Proteins
Help the institute with computing power and brain power by becoming involved in one of these programs.
For more information about the UW Institute for Protein Design, please contact Karen Franklin, UW Medicine Advancement, at firstname.lastname@example.org, 206.543.7421.
Thank you for your interest in our work.