CURRENT CLINICAL INTERESTS
General hematology/oncology; myeloproliferative diseases, HIV hematology-oncology
Broudy VC, Lin NL, Sabath DF, Papayannopoulou T, Kaushansky K: Human platelets display high affinity receptors for thrombopoietin.
Blood 89:1896-1904, 1997.
Sabath DF, Kaushansky K, Broudy VC: Deletion of the extracellular membrane-distal cytokine receptor homology module of Mpl results in constitutive cell growth and loss of thrombopoietin binding.
Blood 94:365-367, 1999.
Sabath DF, Lin N, Kaushansky K, Sabath DE, Broudy
VC: Tyrosine 462 of the membrane-proximal F’-G’ loop of murine Mpl is not essential for high-affinity binding of thrombopoietin.
Cytokine 12:127-133, 2000.
Broudy VC, Lin NL, Sabath DF: The fifth immunoglobulin-like domain of the Kit receptor is required for proteolytic cleavage from the cell surface.
Cytokine 15:188-195, 2001.
Otto KG, Broudy VC, Lin NL, Parganas E, Luthi JN, Drachman JG, Ihle JN, Blau CA: Membrane localization is not required for Mpl function in normal hematopoietic cells.
Blood 98:2077-2083, 2001.
Broudy VC, Lin NL: AMG531 stimulates
megakaryopoiesis in vitro by binding to Mpl. Cytokine 25:52-60,
Broudy VC, Hickman S: Teachng hematology to
second year medical students: results of a national survey of
hematology course directors. Annals of Hematology 86:283-287,