CURRENT CLINICAL INTERESTS
Hematologic malignancies, benign hematologic disorders, bleeding and thrombotic disorders, therapeutic apheresis and stem cell procurement.
CURRENT RESEARCH INTERESTS
Safe and effective
management of patients and donors undergoing marrow harvest and
peripheral blood stem cell mobilization and collection by apheresis.
In his role as Medical Director of Apheresis and Cellular Therapy, Dr. Linenberger supports the activities of the Cell Processing Core of the Fred Hutchinson Cancer Research Center, which provides critical instrumentation and technical expertise for the procurement, characterization and processing of all clinical cellular components necessary for the treatment of patients and for correlative research studies. These activities support the investigational protocols that utilize the Cellular Processing Facility (a GMP production laboratory) and a research speciment repository.
Makar RS, Padmanabhan A, Kim HC, Anderson C, Sugrue MW, Linenberger M. Use of laboratory tests to guide initiation of autologous hematopoietic progenitor cell collection by apheresis [HPC(A)]: results from the multicenter HPC(A) laboratory trigger survey. Transfusion Med Rev 2014;28(4):198-204.
Connelly-Smith LS, Linenberger ML. Therapeutic apheresis for patients with cancer. Cancer Control. 2015;22(1):60-78.
Phipps C, Linenberger M, Holmberg LA, Green D, Becker P, Connelly-Smith L, Klippel Z, Burwick N, Gopal A, Bensinger WI, Libby E. Utilization of stored autologous PBSCs to support second autologous transplantation in multiple myeloma patients in the era of novel agent therapy. Bone Marrow Transplant. 2015;50(5):663-7.
Karafin MS, Sachais BS, Connelly-Smith L, Field JJ, Linenberger ML, Padmanabhan A. NHLBI state of the science symposium in therapeutic apheresis: Knowledge gaps and research opportunities in the area of hematology-oncology. J Clin Apher. 2015 May 4.
Roberts TK and Linenberger ML. A case of benign Pelger Huet anomaly. Blood 2015;126(5):693.
Schmitz-Abe K, Ciesielski SJ, Schmidt PJ, Campagna DR, Rahimov F, Schilke BA, Cuijpers M, Rieneck K, Lausen B, Linenberger ML, Sendamarai AK, Guo C, Hofmann I, Newburger PE, Matthews D, Shimamura A, Snijders PJ, Towne MC, Niemeyer CM, Watson HG, Dziegiel MH, Heeney MM, May A, Bottomley SS, Swinkels DW, Markianos K, Craig EA, Fleming MD. Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9. Blood. 2015;126(25):2734-8.
O'Leary MF, Dunbar NM, Kim HC, Draper NL, Linenberger M, Schwartz J, Miller Y, Murtaugh A, West FB, Fernando LP, Park YA. Venous access for hematopoietic progenitor cell collection: An international survey by the ASFA HPC donor subcommittee. J Clin Apher. 2016 Jan 13 [Epub ahead of print].