Postexposure Prophylaxis after Exposure to Hepatitis A Virus

You answered:

B Administer immune globulin (IG) only.

This answer is incorrect. Although in the past immune globulin (IG) would have been recommended for HAV postexposure prophylaxis in this setting, HAV vaccine is now the preferred method for hepatitis A postexposure prophylaxis for healthy persons aged 12 months-40 years of age. For this individual, the use of hepatitis A vaccine has an added benefit as this patient also needs long-term protection against future HAV infection, because men who have sex with men are at increased risk for acquiring HAV. For some patient populations, such as children younger than 12 months of age, immunocompromised individuals, and persons with a diagnosis of chronic liver disease, the use of IG is still preferred for hepatitis A postexposure prophylaxis.

Choose another answer:

A Administer hepatitis A vaccine.
C Administer lamivudine for 28 days.
D Do not administer immune globulin (IG) or hepatitis A vaccine because too much time has passed since the patient was last exposed.

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