Antiviral Agents Used to Treat Hepatitis B Virus Infection

You answered:

C Tenofovir (Viread) should not be considered an option for this patient because of the unacceptably high incidence of tenofovir-induced renal failure in Asian patients.

This answer is incorrect. Although tenofovir can cause renal insufficiency, this adverse effect occurs infrequently, especially in persons without any co-morbid medical conditions. Further, there is no evidence that Asian patients have a higher incidence of tenofovir-induced renal insufficiency.

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A A major drawback for the use of peginterferon alfa-2a (Pegasys) is the rapid development of HBV resistance.
B Telbivudine (Tyzeka) and lamivudine (Epivir-HBV) are both L-nucleoside analogues that share cross-resistance.
D The same dose of entecavir (Baraclude) can be used for treatment-naïve patients and lamivudine-resistant patients.

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