Approach to HBsAg-Positive Patients
This answer is incorrect. The standard assay for anti-HBc detects total anti-HBc, and does not distinguish between IgG and IgM components. The anti-HBc IgG isotype appears approximately 4-6 months after acute hepatitis B infection, and remains positive for life. Thus, detection of anti-HBc does not indicate acute hepatitis B infection. In this patient, it is not yet clear whether he has acute or chronic hepatitis B infection, because he has never had HBsAg measured in the past. He requires a complete hepatitis B serology as part of the workup of hepatitis B infection. This should also include a test for IgM anti-HBc.
Choose another answer: