Approach to HBsAg-Positive Patients
This answer is incorrect. HBeAg should be measured as part of the initial workup, but alone cannot determine if the patient has active hepatitis B infection. The presence of HBeAg indicates viral replication, and can be detected in persons with chronic active HBV infection as well as in those with acute infection. The exception is the patient with a precore mutant strain of hepatitis B virus, whose blood work will demonstrate a high HBV DNA level despite a negative HBeAg serologic test.
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