Approach to HBeAg-Negative Patients with Increased Hepatic Aminotransferase Levels
This answer is incorrect. Although the risk of developing liver cancer is increased in all patients with chronic hepatitis B patients, in this case hepatocellular carcinoma (HCC) is not the most likely diagnosis. Although HCC is 2-10 times more likely to occur in chronic HBsAg-positive hepatitis B carriers compared with HBsAg-negative individuals, only a fraction of carriers are expected to develop HCC within their lifetime. In addition to HBsAg positivity, risk factors for HCC include male gender, age over 40, being HBeAg positive, high serum HBV DNA levels, and underlying cirrhosis.
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