Hepatitis Web Study

Learning Objectives

Upon completing the module Hepatitis B, participants should be able to:

  1. List the major stages of chronic hepatitis B virus infection.
  2. Summarize the natural history of patients following acute hepatitis B virus infection.
  3. Describe the serologic response that occurs in response to acute hepatitis B virus infection.
  4. Discuss the serologic responsess that occurs in patients with resolved HBV infection.
  5. List the potential causes of a finding of isolated hepatitis B core antibody in serum.
  6. Discuss the approach to patients with isolated hepatitis B core antibody.
  7. Summarize the initial assessment of patients with positive hepatitis B surface antigen (HBsAg).
  8. Interpret laboratory tests used to evaluate patients with positive hepatitis B surface antigen (HBsAg).
  9. Explain how precore and core promoter mutations alter hepatitis B e antigen (HBeAg) production.
  10. Describe the clinical implications and management of precore and core promoter mutants.
  11. Understand the goals of therapy for chronic hepatitis B infection.
  12. Discuss when to initiate therapy for patients with chronic hepatitis B infection.
  13. List and compare the agents approved to treat hepatitis B.
  14. Describe the different virologic responses to antiviral therapy for hepatitis B.
  15. Understand basic resistance terminology.
  16. Discuss the approach to managing a patient with virologic breakthrough on antiviral therapy for hepatitis B.
  17. Summarize the risk of transmission of hepatitis B virus to a susceptible health care worker compared with other bloodborne pathogens.
  18. Describe the appropriate evaluation and management of health care workers who have occupational exposure to hepatitis B virus.
  19. Explain the HBV screening recommendations for pregnant women.
  20. List the the hepatitis B immunoprophylaxis recommendations for neonates.