Learning Objectives
Upon completing the module Hepatitis B, participants should be able to:
- List the major stages of chronic hepatitis B virus infection.
- Summarize the natural history of patients following acute hepatitis
B virus infection.
- Describe the typical serologic response that
occurs in response to acute hepatitis B virus infection.
- List the
potential causes of a finding of isolated hepatitis B core antibody
in serum.
- Discuss the approach to patients with isolated hepatitis
B core antibody.
- Summarize the initial assessment of patients with
positive hepatitis B surface antigen (HBsAg).
- Interpret laboratory
tests used to further evaluate patients who have a positive hepatitis
B surface antigen (HBsAg) test.
- Explain the mechanism for how
precore and core promoter mutations lead to altered production of hepatitis
B e antigen (HBeAg).
- Describe the clinical implications and management
of precore and core promoter mutants.
- Summarize the risk of transmission
of hepatitis B virus to a susceptible health care worker compared with
other bloodborne pathogens.
- Discuss the appropriate evaluation
and management of health care workers who have occupational exposure
to hepatitis B virus.
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