Management of Treatment-Naïve Genotypes 2 and 3 HCV Infection

You answered:

C Weight-based dosing of ribavirin is mandatory for optimal response with genotype 2.

This answer is incorrect. Weight-based dosing of ribavirin is not mandatory for genotype 2 infection and may be excessive. A lower fixed dose of 800 mg daily is sufficient in most individuals.

A HCV genotype 2 infection is generally associated with higher sustained virologic response rates compared with other HCV genotypes.
B Treatment with peginterferon and ribavirin should last 48 weeks to optimize response rates in genotype 2.
D The recommended duration of therapy for HCV genotype 2 infection with peginterferon and ribavirin is 12 weeks.

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