Medications Used in Hepatitis C Treatment

You answered:

A The patient should receive ribavirin as a fixed dose of 800 mg per day in this regimen.

This answer is incorrect. All patients with genotype 1 hepatitis C require weight-based ribavirin dosing during combination therapy with peginterferon and one of the hepatitis C protease inhibitors. The fixed 800 mg daily dosing of ribavirin is reserved for those with genotype 2 or 3 infection.

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B Uncontrolled systemic lupus erythematosus is a contraindication to treatment with peginterferon.
C Thrombocytopenia is the most common cytopenia attributable to the hepatitis C protease inhibitors.
D Telaprevir is dosed three times daily and must be taken on an empty stomach.

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