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UW Virology Research ClinicPublications

General Information
Detection and Testing
Viral Shedding
Treatment
Transmission
Pregnancy
Vaccines
HIV/HSV

 

General Information

Peripheral blood CD4 T-cell and pDC reactivity to HSV-2 and pDC number do not correlate with the severity of recurrent genital herpes
HSV-2 serologic testing in an HMO population: uptake and psychosocial sequelae
Genital herpes in a primary care clinic: demographic and sexual correlates of herpes simplex type 2 infection
Evidence of latency and reactivation of both herpes simplex virus (HSV-1) and HSV-2 in the genital region
An interactive, computer-based program to educate patients about genital herpes
Herpes simplex virus viremia during primary genital infection

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Detection and Testing

Type-specific testing for herpes simplex virus
Genital herpes: review of the epidemic and potential uses of type-specific serology
Premarket evaluation of the POCkit TM HSV-2 type specific serologic test in culture-documented cases of HSV-2

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Viral Shedding

Genital Shedding of Herpes Simplex Virus Among Symptomatic and Asymptomatic Persons With HSV-2 Infection
Oral shedding of herpes simplex virus type 2
Genital HSV-1 infections
Frequent genital HSV-2 shedding in immunocompetent women
Virologic characteristics of subclinical and symptomatic genital herpes infections

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Treatment

Valacyclovir and acyclovir for suppression of shedding of herpes simplex virus in the genital tract
Famciclovir Reduces Viral Mucosal Shedding in HSV-Seropositive Persons
New therapies and prevention strategies for genital herpes
Suppression of subclinical shedding of herpes simplex virus type 2 with acyclovir
Management of genital herpes

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Transmission

Knowledge of partners' genital herpes protects against herpes simplex virus type 2 acquisition
Once-daily valacyclovir to reduce the risk of transmission of genital herpes
Effect of condoms on reducing the transmission of herpes simplex virus type 2 from men to women
The relationship between condom use and herpes simplex virus acquisition

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Pregnancy

Genital herpes complicating pregnancy
Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant
Preventing herpes simplex virus transmission to the neonate
The acquisition of herpes simplex virus during pregnancy
Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor

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Vaccines

Immunotherapy of recurrent genital herpes with recombinant herpes simplex virus type 2 glycoproteins D and B: results of a placebo-controlled trial

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HIV/HSV

The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: a review of two overlapping epidemics
Severe genital herpes infections in HIV-infected individuals with impaired herpes simplex virus specific CD8 + cytotoxic T lymphocytes responses
Frequent recovery of HIV from genital herpes simplex virus lesions in HIV infected persons
Frequency of symptomatic and asymptomatic HSV-2 reactivations among HIV-infected men
Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double-blind, placebo-controlled, crossover trial

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