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General Information Detection and Testing Viral Shedding Treatment Transmission Pregnancy Vaccines HIV/HSV
General Information • Peripheral blood CD4 T-cell and pDC reactivity to HSV-2 and pDC number do not correlate with the severity of recurrent genital herpes • HSV-2 serologic testing in an HMO population: uptake and psychosocial sequelae • Genital herpes in a primary care clinic: demographic and sexual correlates of herpes simplex type 2 infection • Evidence of latency and reactivation of both herpes simplex virus (HSV-1) and HSV-2 in the genital region • An interactive, computer-based program to educate patients about genital herpes • Herpes simplex virus viremia during primary genital infection
(back) Detection and Testing • Type-specific testing for herpes simplex virus • Genital herpes: review of the epidemic and potential uses of type-specific serology • Premarket evaluation of the POCkit TM HSV-2 type specific serologic test in culture-documented cases of HSV-2
(back) Viral Shedding • Genital Shedding of Herpes Simplex Virus Among Symptomatic and Asymptomatic Persons With HSV-2 Infection • Oral shedding of herpes simplex virus type 2 • Genital HSV-1 infections • Frequent genital HSV-2 shedding in immunocompetent women • Virologic characteristics of subclinical and symptomatic genital herpes infections
(back) Treatment • Valacyclovir and acyclovir for suppression of shedding of herpes simplex virus in the genital tract • Famciclovir Reduces Viral Mucosal Shedding in HSV-Seropositive Persons • New therapies and prevention strategies for genital herpes • Suppression of subclinical shedding of herpes simplex virus type 2 with acyclovir • Management of genital herpes
(back) Transmission • Knowledge of partners' genital herpes protects against herpes simplex virus type 2 acquisition • Once-daily valacyclovir to reduce the risk of transmission of genital herpes • Effect of condoms on reducing the transmission of herpes simplex virus type 2 from men to women • The relationship between condom use and herpes simplex virus acquisition
(back) Pregnancy • Genital herpes complicating pregnancy • Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant • Preventing herpes simplex virus transmission to the neonate • The acquisition of herpes simplex virus during pregnancy • Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor
(back) Vaccines • Immunotherapy of recurrent genital herpes with recombinant herpes simplex virus type 2 glycoproteins D and B: results of a placebo-controlled trial
(back) HIV/HSV • The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: a review of two overlapping epidemics • Severe genital herpes infections in HIV-infected individuals with impaired herpes simplex virus specific CD8 + cytotoxic T lymphocytes responses • Frequent recovery of HIV from genital herpes simplex virus lesions in HIV infected persons • Frequency of symptomatic and asymptomatic HSV-2 reactivations among HIV-infected men • Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double-blind, placebo-controlled, crossover trial
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