In addition to the regular class meetings, graduate students enrolled in Biological Frameworks for Engineers are required to attend a weekly 60-minute "journal club" session. (The journal club is optional for undergraduates.) Each journal club session is an instructor-led discussion of a piece of literature handed out a week earlier along with a study guide. Sample assignments are listed below.
Introduction
to the "Breakthroughs in Biology" series
(required for graduate students enrolled in EE 546; optional for everyone else)
| Article List | Study Guide |
| M. B. Elowitz and S. Leibler, "A
synthetic oscillatory network of transcriptional regulators," Nature
403: 335-338, 2000. |
Study Guide |
| Walter Gilbert and Benno
Müller-Hill, “The lac operator is DNA,” Proceedings
of the National Academy of Sciences USA 58: 2415-2421, 1967. |
Study Guide |
| V. M. Ingram, "Gene
mutations in hæmoglobin: the chemical difference between normal
and sickle-cell hæmoglobin," Nature 180: 326-328, 1957. |
Study Guide |
| E. R. Kandel, "Calcium
and the control of synaptic strength by learning," Nature 293: 697-700,
1981. |
Study Guide |
| K. P. Lemon and A. D.
Grossman, "Localization of bacterial DNA polymerase: evidence for
a factory model of replication," Science 282: 1516-1519, 1998. |
Study Guide |
| S. L. Lindstedt et al., "Limitations
to aerobic performance in mammals: interaction of structure and demand," International
Journal of Sport Medicine 9: 210-217, 1988. |
Study Guide |
| H.-R. Lüscher et
al., “How the size of motoneurones determines their susceptibility
to discharge,” Nature 282: 859-861, 1979. |
Study Guide |
| G. J. Lutz and L. C. Rome, “Built
for jumping: the design of the frog muscular system,” Science 263:
370-372, 1994. |
Study Guide |
| E. M. Purcell, “Life
at low Reynolds number,” American Journal of Physics 45: 3-11,
1977. |
Study Guide |
| F. Sanger et al., "DNA
sequencing with chain-terminating inhibitors," Proceedings of the
National Academy of Sciences USA 74: 5463-5467, 1977. |
Study Guide |
| Y. Shav-Tal et al., “Dynamics
of single mRNPs in nuclei of living cells,” Science 304: 1797-1800,
2004. |
Study Guide |
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