In addition to the regular class meetings, graduate students enrolled in Biological Frameworks for Engineers are required to attend a weekly 60-minute "journal club" session. (The journal club is optional for undergraduates.) Each journal club session is an instructor-led discussion of a piece of literature handed out a week earlier along with a study guide. Sample assignments are listed below.

Introduction to the "Breakthroughs in Biology" series
(required for graduate students enrolled in EE 546; optional for everyone else)

Article List Study Guide
M. B. Elowitz and S. Leibler, "A synthetic oscillatory network of transcriptional regulators," Nature 403: 335-338, 2000. Study Guide
Walter Gilbert and Benno Müller-Hill, “The lac operator is DNA,” Proceedings of the National Academy of Sciences USA 58: 2415-2421, 1967. Study Guide
V. M. Ingram, "Gene mutations in hæmoglobin: the chemical difference between normal and sickle-cell hæmoglobin," Nature 180: 326-328, 1957. Study Guide
E. R. Kandel, "Calcium and the control of synaptic strength by learning," Nature 293: 697-700, 1981. Study Guide
K. P. Lemon and A. D. Grossman, "Localization of bacterial DNA polymerase: evidence for a factory model of replication," Science 282: 1516-1519, 1998. Study Guide
S. L. Lindstedt et al., "Limitations to aerobic performance in mammals: interaction of structure and demand," International Journal of Sport Medicine 9: 210-217, 1988. Study Guide
H.-R. Lüscher et al., “How the size of motoneurones determines their susceptibility to discharge,” Nature 282: 859-861, 1979. Study Guide
G. J. Lutz and L. C. Rome, “Built for jumping: the design of the frog muscular system,” Science 263: 370-372, 1994. Study Guide
E. M. Purcell, “Life at low Reynolds number,” American Journal of Physics 45: 3-11, 1977. Study Guide
F. Sanger et al., "DNA sequencing with chain-terminating inhibitors," Proceedings of the National Academy of Sciences USA 74: 5463-5467, 1977. Study Guide
Y. Shav-Tal et al., “Dynamics of single mRNPs in nuclei of living cells,” Science 304: 1797-1800, 2004. Study Guide


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Journal Article Study Guides