Question | Discussion | References | CME Credit

Case 5: Discordant CD4 Cell Count and Viral Load Responses to Antiretroviral Therapy

You answered:

A Give subcutaneous interleukin-2 twice daily for 5 consecutive days every 8 weeks until the CD4 count is greater than 200 cells/mm3.

This answer is incorrect. Although interleukin-2 increases CD4 cell count, recent studies showed no clinical benefit.

Choose another answer:

B Switch the atazanavir plus ritonavir to lopinavir-ritonavir (Kaletra).
C Discontinue antiretroviral therapy, since it appears the patient has not had a good CD4 cell count recovery.
D Continue the current antiretroviral regimen and Pneumocystis prophylaxis, but discontinue azithromycin.

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