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Case 4: Varicella Zoster Virus

You answered:

D The incidence of herpes zoster in HIV-infected individuals is the same as age-matched HIV-negative persons.

This answer is incorrect. The incidence of zoster among HIV-infected adults is more than 10-fold greater than age-matched immunocompetent persons.

A The Tzanck stain is diagnostic for VZV infection and it rules out other causes of vesicular skin lesions, such as herpes simplex virus infection.
B The preferred therapy for dermatomal herpes zoster in HIV-infected patients consists of acyclovir (Zovirax), valacyclovir (Valtrex), or famciclovir (Famvir).
C The preferred therapy for dermatomal herpes zoster in HIV-infected patients consists of oral valganciclovir (Valcyte).

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