Question | Discussion | References | CME Credit

Case 1: Antiretrovirals used with Antidepressants and Mood Stabilizers

You answered:

A Immune reconstitution inflammatory syndrome in the central nervous system

This answer is incorrect. Antiretroviral therapy can cause an immune reconstitution inflammatory syndrome in the central nervous system, particularly in patients with high cerebrospinal fluid HIV RNA levels. In this patient, the clinical presentation is more consistent with worsening of depression.

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B Tenofovir-induced increase in lithium levels.
C Lopinavir-ritonavir-induced decrease in lamotrigine levels.
D Emtricitabine-induced decrease in lithium levels

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