Case 1: Drug Interactions with Antiretroviral Medications

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OIs: Prophylaxis
OIs: Treatment
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Antiretroviral Rx: Resistance
Antiretroviral Rx: Adverse Effects
Drug-Drug Interactions
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Question | Discussion | References | CME Credit

You answered:

	Didanosine enteric-coated capsules (Videx EC) will markedly decrease the absorption of indinavir.

This answer is incorrect. There is no significant drug-drug interaction between indinavir and the newer didanosine enteric-coated capsules (Videx EC). The older didanosine buffered tablets, however, cause significant drug-drug interactions and can significantly decrease indinavir absorption.

Choose another answer:

	Ritonavir can significantly increase levels of sildenafil.
	Ritonavir significantly decreases the half-life of indinavir.
	Lamivudine significantly lowers ritonavir levels.

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