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Case 3: Antiretrovirals and Methadone

You answered:

C Decrease her dose of methadone

This answer is incorrect. The symptoms the patient is experiencing are consistent with opioid withdrawal and this likely has resulted from a drug-drug interaction between efavirenz and methadone. Lowering her dose of methadone will make the situation worse.

A Immediately stop the antiretroviral regimen
B Increase her dose of methadone
D Start a benzodiazepine to treat her anxiety

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