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Case 4: Antiretrovirals and Oral Contraceptives

You answered:

D Lopinavir-ritonavir (Kaletra) will not impact ethinyl estradiol and norethindrone levels.

This answer is incorrect. Lopinavir-ritonavir decreases ethinyl estradiol and norethindrone levels by 42% and 17%, respectively.

Choose another answer:

A Efavirenz (Sustiva) will likely reduce the efficacy of the oral contraceptive pill.
B Raltegravir (Isentress) will markedly lower ethinyl estradiol and norethindrone levels.
C Darunavir (Prezista) boosted with ritonavir (Norvir) will significantly increase ethinyl estradiol and norethindrone levels.

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