Case 2: HIV Classification

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Case last updated: September 30, 2008

A 27-year-old HIV-infected woman has recently been diagnosed with HIV infection and she comes to the clinic for her first evaluation. She believes she was likely infected with HIV approximately 4 years ago. Three weeks prior to this visit, she had a Papanicolaou (Pap) smear result that showed severe cervical dysplasia and this Pap smear result prompted the HIV testing. Her physical examination shows oral candidiasis and oral hairy leukoplakia. She does not have any other HIV-related manifestations and she has no history of HIV-related complications. Her CD4 count is 238 cells/mm3 (CD4 percentage is 12%); the test is repeated 2 weeks later and the CD4 count is 243 cells/mm3 (CD4 percentage is 11%). Her HIV RNA value is 187,000 copies/ml.

According to the 1993 CDC Classification for HIV Infection among adolescents and adults, which of the following statements is TRUE?

	The HIV RNA value greater than 100,000 copies/ml has great prognostic significance and is an AIDS-defining condition.
	The diagnosis of severe cervical dysplasia is a category C AIDS-defining condition.
	The simultaneous presence of oral candidiasis and oral hairy leukoplakia would give her a category C AIDS-defining diagnosis.
	Her CD4 percentage of 12% is an AIDS-defining value even though her absolute CD4 count value is not less than 200 cells/mm3.
	If the patient has clinical resolution of both the oral candidiasis and the oral hairy leukoplakia, the classification of her clinical category will be revised from B to A.