Question | Discussion | References | CME Credit

Case 3: Appropriate Serologic Testing

You answered:

A anti-Toxoplasma IgG

This answer is correct, but other answers are also correct. Serologic testing to determine previous infection with Toxoplasma gondii is indicated for all patients infected with HIV. Almost all cases of toxoplasmosis involving HIV-infected persons occur as a result of reactivation. According to USPHS/IDSA guidelines, patients who are seropositive for anti-Toxoplasma IgG should initiate primary prophylaxis against toxoplasmic encephalitis when the CD4 count is less than 100 cells/mm3. Knowledge of Toxoplasma serostatus is also useful in the evaluation of brain mass lesions, though it does not establish or exclude the diagnosis. Patients without evidence of prior Toxoplasma infection can be counseled in ways to prevent infection.

Choose another answer:

B Hepatitis A, B, and C serologies
C anti-Histoplasma IgG
D Venereal Disease Research Lab (VDRL) or Rapid Plasma Reagin (RPR)
E A, B, and D

[Back to Case 3 Question | Go to Correct Answer]