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Case 1: A 39-Year-Old with Headache, Fever, and Confusion

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B The patient's clinical history is compatible with cryptococcal meningitis. The diagnosis of cryptococcal meningitis should not be ruled out with only 7 leukocytes/mm3 found in the cerebrospinal fluid.

This answer is correct. The patient's clinical history is consistent with cryptococcal meningitis and the low cerebrospinal fluid leukocyte count does not rule out this diagnosis. More than 50% of AIDS patients with acute cryptococcal meningitis will have a cerebrospinal fluid WBC count less than 20 leukocytes/mm3. A low cerebrospinal fluid leukocyte count has been associated with more serious disease and is considered a poor prognostic sign.

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