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Case 1: Antiretroviral Therapy During Pregnancy to Prevent Perinatal HIV Transmission

You answered:

E Start stavudine (Zerit) plus didanosine (Videx EC) plus nelfinavir (Viracept).

This answer is incorrect. Stavudine and didanosine should not be used together in pregnancy unless no other option is available, due to the increased risk of patient’s developing lactic acidosis when these agents are used together.

Choose another answer:

Choose another answer:

A No antiretroviral therapy is indicated at this stage of the pregnancy. Consider starting antiretroviral therapy if the mother’s HIV RNA increases to greater than 50,000 copies/ml.
B Start zidovudine plus lamivudine (Combivir) plus nevirapine (Viramune). Consider switching nevirapine to efavirenz (Sustiva) if she does not tolerate nevirapine.
C Start stavudine (Zerit) plus lamivudine (Epivir) plus nelfinavir (Viracept). Consider switching stavudine to zidovudine (Retrovir) if the anemia improves significantly.
D Start zidovudine (Retrovir) monotherapy. Consider adding lamivudine (Epivir) in the third trimester.

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