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Case 2: Initial Evaluation and Postexposure Prophylaxis

You answered:

A PEP is not indicated at this time because too much time has elapsed since the exposure.

This answer is incorrect. Although animal studies suggest that PEP is more effective if administered within several hours of an exposure, the interval beyond which PEP is no longer effective in humans is not known. Hence, the administration of PEP 24 hours following an exposure is reasonable.

Choose another answer:

B PEP should be initiated if viral load testing on the source patient reveals a high viral load.
C A two-drug PEP regimen should be initiated immediately.
D A three-drug PEP regimen should be initiated immediately.

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