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Case 3: Management of a Needlestick Injury: Source Patient of Unknown Serostatus

You answered:

C Offer PEP if rapid testing of the needle that caused the injury suggests the presence of HIV.

This answer is incorrect. Testing of needles or other sharps for the presence of HIV following a percutaneous injury is not recommended because the accuracy of HIV testing in this setting is not clear.

A Do not offer PEP because the source patient is not known to be HIV-infected and the mechanism of injury is low-risk for HIV transmission.
B Offer PEP only if testing of the source patient confirms that he is HIV-infected.
D Offer PEP with zidovudine plus lamivudine (Combivir) and perform HIV testing on the source patient as soon as it is possible.

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