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Case 1: Methamphetamine Use and HIV

You answered:

C Methamphetamine and nucleoside reverse transcriptase inhibitors (NRTIs) do not appear to have significant drug-drug interactions.

This answer is correct. Available data suggest that nucleoside reverse transcriptase inhibitors (NRTIs) do not have significant drug-drug interactions with methamphetamine. Similarly, non-nucleoside reverse transcriptase inhibitors (NNRTIs) do not appear to have a significant drug-drug interaction with methamphetamine. In contrast, however, the protease inhibitor ritonavir (Norvir), can more than double methamphetamine levels, and the combination of methamphetamine and ritonavir has been associated with methamphetamine overdose.


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