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Case 3: A 44-Year-Old with Unusual Changes in Physical Appearance

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B Cushing’s syndrome caused by an interaction between fluticasone and ritonavir.

This answer is correct. Ritonavir is a potent inhibitor of the CYP 3A4 enzyme; it can significantly increase systemic levels of fluticasone, a potent inhaled corticosteroid. This interaction can lead to hypercortisolism and symptoms of Cushing’s syndrome.

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