Katherine Luzuriaga

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Katherine Luzuriaga, M.D.
Professor, Molecular Medicine, Pediatrics, and Medicine
Director, UMass Center for Clinical and Translational Science
Vice Provost, Clinical and Translational Research
University of Massachusetts Medical School
Worcester, MA
Dr. Luzuriaga is Professor of Molecular Medicine, Pediatrics, and Medicine; Director of the UMass Center for Clinical and Translational Science (UMCCTS); and Vice Provost for Clinical and Translational Research at the University of Massachusetts Medical School.  As a physician-scientist, her research, focused on understanding viral and host factors that result in persistent viral (HIV, EBV, CMV) infections in children, has provided multiple insights relevant to HIV cure, including the genetic and biologic characterization of variants that are transmitted from women to their infants, the dynamics of early viral replication and HIV reservoir formation in infants, the ontogeny of HIV-1 specific immune responses in HIV-infected infants, and defining the role of HIV-1 specific CD8+ T cells in controlling viral replication or evolution of the HIV quasispecies.  She has also been active in translational research that helped to define the timing of mother-to-child HIV transmission, led to the pediatric labeling of multiple antiretrovirals (including nevirapine), and she led the first early therapy trials in infants.  Her research has been supported over the years by RO1 and P01 funding from the National Institutes of Health, the Charles Hood Foundation, the Elizabeth Glaser Pediatric AIDS Foundation, and the American Foundation for AIDS Research (Amfar).  Dr. Luzuriaga has held several leadership positions within the US National Institutes of Health-sponsored Pediatric AIDS Clinical Trials and IMPAACT Groups, and currently serves on the NIH NCATS-CTSA Steering Committee. She has served as a consultant to the World Health Organization, as a member of the Institute of Medicine’s Committee on the Perinatal Transmission of HIV, and as a member of the NIH Office of AIDS Research Etiology and Pathogenesis Planning Committee. Dr. Luzuriaga is a recipient of a Scholar Award and an Elizabeth Glaser Scientist Award from the Elizabeth Glaser Pediatric AIDS Foundation. Named to the 2013 TIME 100 Most Influential People in the World and the 2013 Foreign Policy Global Thinkers lists, Dr. Luzuriaga is particularly interested in communicating to policy makers and the public the importance of scientific investigation for improving health.