The University of Washington

HIV Primary Infection Clinic

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ACTG 5217:  The SETPOINT Study

A Randomized Study of the Effect of Immediate Treatment with Potent Antiretroviral Therapy versus Observation with Treatment as Indicated in Newly HIV-I infected Subjects: Does Early Therapy Alter the Virologic Setpoint?

It is not known whether or not treatment is beneficial soon after someone acquires HIV infection. Some studies suggest that early treatment is more helpful in preserving the immune system. It is also possible that early treatment might cause more medication side effects. It is not known whether early treatment of HIV infection makes a difference in the long-run.

This study is designed to help answer these questions. During this study, one group of people will take HIV treatment for nine months during early infection and the other group will remain untreated  (unless they develop low CD4 cell counts or high viral loads).  

More information about this study, including eligibility requirements, may be found at:
http://depts.washington.edu/actu/study/fact5217.htm
http://www.medical.washington.edu/studies/study_details.asp?study=055509B01

If you think you might be eligible and are interested in getting more information, or have questions about acute infection, call us at (206) 521-1978 or email us.