The University of Washington

HIV Primary Infection Clinic

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McElrath Lab
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Virology

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Virology papers and absctracts

Compartmentalization of Human Immunodeficiency Virus Type 1 between Blood Monocytes and CD4+ T Cells during Infection
by Jennifer A. Fulcher, Yon Hwangbo, Rafael Zioni, David Nickle, Xudong Lin, Laura Heath, James I. Mullins, Lawrence Corey, and Tuofu Zhu. Published in the Journal of Virology, March 2004.

Virus Population Homogenization following Acute Human Immunodeficiency Virus Type 1 Infection
by Gerald H. Learn, David Muthui, Scott J. Brodie, Tuofu Zhu, Kurt Diem, James I. Mullins, and Lawrence Corey. Published in the Journal of Virology, December 2002.

Selection for human immunodeficiency virus type 1 recombinants in a patient with rapid progression to AIDS
by Liu SL, Mittler JE, Nickle DC, Mulvania TM, Shriner D, Rodrigo AG, Kosloff B, He Z, Corey L, Mullins JI. Published in the Journal of Virology, November 2002.

Evidence for Human Immunodeficiency Virus Type 1 Replication In Vivo in CD14+ Monocytes and Its Potential Role as a Source of Virus in Patients on Highly Active Antiretroviral Therapy
by Tuofu Zhu, David Muthui, Sarah Holte, David Nickle, Feng Feng, Scott Brodie, Yon Hwangbo, James I. Mullins, and Lawrence Corey. Published in the Journal of Virology, January 2002.

Early establishment of a pool of latently infected, resting CD4+ T cells during primary HIV-1 infection
by Tae-Wook Chun, Delphine Engel, M. Michelle Berrey, Theresa Shea, Lawrence Corey, and Anthony S. Fauci . Published in PNAS, July 21, 1998.

Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: implications for antiviral therapy
by Pantaleo G, Cohen OJ, Schacker T, Vaccarezza M, Graziosi C, Rizzardi GP, Kahn J, Fox CH, Schnittman SM, Schwartz DH, Corey L, Fauci AS . Published in Nature Medicine, March, 1998.

Divergent patterns of progression to AIDS after infection from the same source: human immunodeficiency virus type 1 evolution and antiviral responses
by SL Liu, T Schacker, L Musey, D Shriner, MJ McElrath, L Corey and JI Mullins. Published in the Journal of Virology, June 1997.

Abstracts

Brodie S, Tabet S, Krieger J, Haggit R, Nickel D, Johnson A, Coombs R, Mullins J, Corey L, Celum C.  Intestinal mucosal macrophages are a principle reservoir of HIV replication and sustained high levels of infectious virus in persons with chronic progressive HIV infection.  Abstract #27, 9th Conference on Retroviruses and Opportunistic Infections, Seattle, WA. February 24-28, 2002.

Fulcher J, Hwangbo Y, Mullins J, Corey L, Zhu T.  Distinct patterns of HIV-1 evolution in CD14+ monocytes and CD4+ T lymphocytes between patients with and without HAART.  Abstract 355-M. 9th Conference on Retroviruses and Opportunistic Infections, Seattle, WA. February 24-28, 2002.

T. Zhu, S. Holte, Y.H. Chang, D. Nickle, F. Feng, D. Muthui, S.Brodie, J. Mullins, L. Corey - Evidence for Production of HIV-1 in Monocytes. International AIDS Meeting, Durban, 2000.

Brodie SJ, Berrey MM, Patterson BK, Zhu T, Diem K, Wood BL, Krieger JN, Corey L.  Comparison of cell-associated HIV-1 DNA and RNA in triple drug-treated versus untreated persons with primary HIV-1: evidence for persistent viral reservoirs. 7th Conf. On retroviruses and opportunistic infections.  Jan. 30-Feb 2, 2000, San Francisco.