Source:
Drug Alcohol Depend 1999 Feb 1;53(3):197-205
Authors:
Woody GE, Donnell D, Seage GR, Metzger D, Marmor M, Koblin BA, Buchbinder S, Gross
M, Stone B, Judson FN.
Publication Info:
University of PA/Philadelphia Veterans Affairs, Medical Center 19104, USA.
woody@research.trc.upenn.edu [Confidentiality cannot be guaranteed for
information provided via e-mail. People visiting websites from public or work
machines may be leaving traces of their visits on those machines.]
Abstract:
Associations between substance use and sexual behavior were examined among 3220
seronegative men who have sex with men (MSM) in a HIV vaccine preparedness study.
Relationships between current and past substance use and current sexual risk were
evaluated using crude odds ratios and logistic regression to adjust for confounding
variables. Heroin and injection drug use were uncommon (< 2%). Substances most often
used were alcohol (89%), marijuana (49%), nitrite inhalants (29%), amphetamines or
similarly acting stimulants (21%), cocaine 14% and hallucinogens (14%). Increased
adjusted odds for unprotected sex were significantly associated with current heavy
alcohol use (OR 1.66; CI 1.18, 2.33), past alcohol problems (OR 1.25; CI 1.05,
1.48), and current drug use (OR 1.26; CI 1.08, 1.48). When associations with
specific drugs and nitrite inhalants were examined separately, current use of
cocaine and other stimulants (OR 1.25; CI 1.01, 1.55), hallucinogens (OR 1.40; CI
1.10, 1.77), and nitrite inhalants (some (OR 1.61; CI 1.35, 1.92); heavy (OR 2.18;
CI 1.48, 3.20)), were independently associated with unprotected sex. Those with past
drug use or past heavy alcohol use but not currently using demonstrated no increase
in sexual risk, suggesting an important role for substance-focused interventions in
risk reduction efforts among MSM.