"Epidemiologic Approaches to Estimate Influenza Vaccine Benefit in Seniors
Speaker: Lisa A. Jackson, MD, MPH, Research Professor, Epidemiology
Adjunct Research Professor, Allergy and Infectious Dis.
Adjunct Research Professor, Medicine
Senior Investigator, Group Health Research Institute
Ninety percent of influenza-associated deaths occur in persons 65 years of age and older and yearly influenza vaccination has been recommended for this group since the 1980s. Estimation of the effectiveness of this intervention using traditional retrospective cohort and case-control study designs has been limited by confounding. This presentation will provide an overview of the epidemiologic approaches to estimation of influenza vaccine effectiveness in seniors, discuss the implications of the available evidence, and ask whether non-randomized studies can answer this question.