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Larry Kessler

faculty photo
Professor, Health Systems and Population Health
Adjunct Professor, Pharmacy


Education

ScD   Johns Hopkins University, 1978   (Health Services Admin)
BS   Boston University, 1973   (Mathematics)

Contact Info

email:   kesslerl@uw.edu

office:   HRC 458

address:
University of Washington
3980 15th Ave NE
Seattle, WA 98195-1621

campus box:   351621
voice:   206-543-2703

About

Larry Kessler is a former Chair of the Department of Health Services. He served as Director of the Office of Surveillance and Biometrics, Center for Devices and Radiological Health, FDA until 2008. From 1984 to 1995, he headed and developed the Applied Research Branch at NCI. In 2001, he spent a year as a visiting scientist at the Fred Hutchinson Cancer Research Center and served on the faculty of the Department of Health Services.


Cost-effectiveness and diagnostic value of medical technology in screening for cancer and other diseases
  • HSERV 512
    Health Systems and Policy
  • HSERV 578
    Preparing, Writing, and Critiquing Scientific Research Proposals


McDaniel CE, Leyenaar J, Sullivan E, Desai S, Kessler L. Pediatric Conditions Requiring Minimal Intervention or Observation After Interfacility Transfer. J Hosp Med. 2021 Jul;16(7):412-415. doi: 10.12788/jhm.3656.  PMID: 34197305
PubMed
 
DOI
 


Bresnahan BW, Jarvik JG, Meier EN, James KT, Gold LS, Rundell SD, Turner JA, Suri P, Luetmer PH, Friedly JL, Sherman KJ, Heagerty PJ, Kallmes DF, Avins AL, Griffith BD, Kessler LG. Expected Organizational Costs for Inserting Prevalence Information Into Lumbar Spine Imaging Reports. J Am Coll Radiol. 2021 Jun 30. pii: S1546-1440(21)00480-4. doi: 10.1016/j.jacr.2021.06.010. [Epub ahead of print]  PMID: 34216559
PubMed
 
DOI
 


Franz N, Rapp H, Hansen RN, Gold LS, Goss CH, Lechtzin N, Kessler LG. Health care costs related to home spirometry in the eICE randomized trial. J Cyst Fibros. 2021 Mar 11. pii: S1569-1993(21)00049-7. doi: 10.1016/j.jcf.2021.02.014. [Epub ahead of print]  PMID: 33715993
PubMed
 
DOI
 


Bizzell B, Kessler LG; CODA Collaborative. A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis. Reply. N Engl J Med. 2021 Mar 4;384(9):881. doi: 10.1056/NEJMc2035865.  PMID: 33657306
PubMed
 
DOI
 


Moran JH, Kessler L, Moylan J, Forrest C, Boehme K, Kennedy J, Greninger A, Baird G, Olgaard E, James L. Modifying laboratory testing via home brew during the COVID-19 pandemic. J Clin Transl Sci. 2021 Jan 25;5(1):e93. doi: 10.1017/cts.2021.5.  PMID: 34192050    PMCID: PMC8134902
PubMed
 
PubMed Central
 
DOI
 


2017
Member, dissertation committee for Shuva Dawadi
Geographic variations in chest-CT scan lung cancer diagnosis from environmental exposures

Health Promotion and Disease Prevention Centers
Centers for Disease Control and Prevention (CDC)
PI:   Hannon           Dates:    9/30/2021 - 9/29/2022

Nanotherm and Prostate Cancer - Phase I
MagForce USA, Inc.
PI:   Kessler           Dates:    6/1/2021 - 12/31/2021

Institute of Translational Health Sciences UL
National Center for Advancing Translational Sciences (NCATS)
PI:   Disis           Dates:    3/1/2021 - 2/28/2022

Cost Effectiveness Analysis and Comparative Effectiveness Research Component of STOP 2
Cystic Fibrosis Foundation Therapeutics, Inc.
PI:   Kessler           Dates:    7/1/2020 - 6/30/2021

Center for Cystic Fibrosis Translational Research in the Post-CFTR modulator Era
Seattle Children's Hospital Research Institute
PI:   Singh           Dates:    6/1/2020 - 5/31/2025

STOP-PEDS Pilot
Trustees of Indiana University
PI:   Kronmal           Dates:    6/1/2020 - 5/31/2021

Institute of Translational Health Sciences UL
National Center for Advancing Translational Sciences (NCATS)
PI:   Disis           Dates:    3/1/2020 - 2/28/2021

Development and pilot testing of measurement tool for diagnosis of lung cancer
Gordon and Betty Moore Foundation
PI:   Thompson           Dates:    1/1/2020 - 6/30/2021

STOP Peds DC
Indiana University
PI:   Kronmal           Dates:    1/1/2020 - 6/30/2020

Cost Effectiveness Analysis and Comparative Effectiveness Research Component of STOP 2
Cystic Fibrosis Foundation Therapeutics, Inc.
PI:   Kessler           Dates:    7/1/2019 - 6/30/2020

Translational Research Center to Expedite Novel Therapies in Cystic Fibrosis
Seattle Children's Hospital Research Institute
PI:   Greenberg           Dates:    6/1/2019 - 5/31/2020

Institute of Translational Health Sciences UL
National Center for Advancing Translational Sciences (NCATS)
PI:   Disis           Dates:    3/1/2019 - 2/29/2020

Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
Patient-Centered Outcomes Research Institute (PCORI)
PI:   Flum           Dates:    1/1/2019 - 12/31/2023

CISTO: Comparison of Intravesical therapy and Surgery as Treatment Options for Recurrent Bladder Cancer
Patient-Centered Outcomes Research Institute (PCORI)
PI:   Gore           Dates:    10/1/2018 - 12/31/2023

Nanotherm and Prostate Cancer - Phase I
MagForce USA, Inc.
PI:   Kessler           Dates:    7/1/2018 - 12/31/2019

Reference Topic Number 0003: Rehabilitation of Patients with Kidney Failure: “Human Factors Considerations for the Ambulatory Kidney to Improve Vitality” (AKTIV)
US Department of Veterans Affairs (VA)
PI:   Kessler           Dates:    7/1/2018 - 6/30/2020

PCORI IDIQ Task Order #12
Patient-Centered Outcomes Research Institute (PCORI)
PI:   Lavallee           Dates:    7/1/2018 - 4/30/2019

Cost Effectiveness Analysis and Comparative Effectiveness Research Component of STOP 2
Cystic Fibrosis Foundation Therapeutics, Inc.
PI:   Kessler           Dates:    7/1/2018 - 6/30/2019

A Pivotal, Prospective, Three-Stage, Single-Arm Study of Focal Ablation of the Prostate with NanoTherm™ Therapy System for a Limited-Volume, Clinically Localized, Intermediate-Risk Prostate Cancer
MagForce USA, Inc.
PI:   Kessler           Dates:    7/1/2018 - 12/31/2019

Translational Research Center to Expedite Novel Therapies in Cystic Fibrosis
Seattle Children's Hospital Research Institute
PI:   Greenberg           Dates:    6/1/2018 - 5/31/2019

Practice Patterns and Impact of Operative and Non-operative Management of Diverticulitis
National Institutes of Health (NIH)
PI:   Flum           Dates:    5/1/2018 - 4/30/2019

Institute of Translational Health Sciences UL
National Center for Advancing Translational Sciences (NCATS)
PI:   Disis           Dates:    3/1/2018 - 2/28/2019

A new Nanotechnology Therapy for Glioblastoma and Prostate Cancer
MagForce USA, Inc.
PI:   Kessler           Dates:    2/1/2018 - 1/31/2019

Institute of Translational Health Sciences
National Center for Advancing Translational Sciences (NCATS)
PI:   Disis           Dates:    6/1/2017 - 5/31/2022

NKC - UW Center for Dialysis Innovation Grant
Northwest Kidney Centers (NKC)
PI:   Himmelfarb           Dates:    3/1/2017 - 7/31/2021

Cost Effectiveness Analysis and Comparative Effectiveness Research Component of STOP 2
Cystic Fibrosis Foundation Therapeutics, Inc.
PI:   Kessler           Dates:    7/1/2016 - 12/31/2019

Comparing Outcomes of Drugs and Appendectomy (CODA)
Patient-Centered Outcomes Research Institute (PCORI)
PI:   Flum           Dates:    4/1/2016 - 1/31/2022

Comparing Outcomes of Drugs and Appendectomy (CODA)
Patient-Centered Outcomes Research Institute (PCORI)
PI:   Flum           Dates:    10/1/2015 - 9/30/2020

Practice Patterns and Impact of Operative and Non-operative Management of Diverticulitis
National Institutes of Health (NIH)
PI:   Flum           Dates:    7/1/2015 - 6/30/2020

Translational Research Center to Expedite Novel Therapies in Cystic Fibrosis
Seattle Children's Hospital Research Institute
PI:   Greenberg           Dates:    6/1/2015 - 5/31/2020

National Emphysema Treatment Trial

Collaborating on a cost-effectiveness study of a very controversial surgical treatment for emphysema patients.


CanCORS

Collaborating on studies of outcomes and patterns of care of both colorectal cancer and lung cancer. We are looking into what kinds of treatment certain types of patients receive and how we can improve the process of obtaining the best cancer care.


CISNET

Collaborating on a study focused on the tremendous increase in the rate of prostate cancer incidence during the 1990's. Much of this disease may represent 'overdiagnosis' which is accompanied by significant loss of quality of life in many cases.