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Larry Kessler
Professor and Chair
Adjunct Professor, Pharmacy

Larry Kessler is the current Chair of the Department of Health Services. Dr. Kessler served as Director of the Office of Surveillance and Biometrics, Center for Devices and Radiological Health, FDA until 2008. From 1984 to 1995, he headed and developed the Applied Research Branch at NCI. In 2001, he spent a year as a visiting scientist at the Fred Hutchinson Cancer Research Center and served on the faculty of the Department of Health Services.

Research Interests:
Cost-effectiveness and diagnostic value of medical technology in screening for cancer and other diseases

Contact Information

email:   kesslerl@u.washington.edu

address:
University of Washington
Department of Health Services
Seattle, WA 98195

campus box:   357660
email:   lkessler@fhcrc.org

address:
Fred Hutchinson Cancer Research Center
Room 903
1100 Fairview Ave., Box MP-900
Seattle, WA 98109

voice:   206-667-6808

Education

ScD   Johns Hopkins University, 1978   (Health Services Admin)
BS   Boston University, 1973   (Mathematics)

Teaching   (Department of Health Services Courses)

  • HSERV 511
    Introduction to Health Services and Public Health
  • HSERV 511
    Introduction to Health Services and Public Health
  • HSERV 592
    Health Services Department Seminar

Recent Publications



Gold LS, Klein G, Carr L, Kessler L, Sullivan SD. The emergence of diagnostic imaging technologies in breast cancer: discovery, regulatory approval, reimbursement, and adoption in clinical guidelines. Cancer Imaging. 2012 Jan 25;12(1):13-24.  PMID: 22275726
PubMed
DOI


Gazelle GS, Kessler L, Lee DW, McGinn T, Menzin J, Neumann PJ, van Amerongen D, White LA; Working Group on Comparative Effectiveness Research for Imaging. A framework for assessing the value of diagnostic imaging in the era of comparative effectiveness research. Radiology. 2011 Dec;261(3):692-8.  PMID: 22095993
PubMed
DOI


Zeliadt SB, Hoffman RM, Etzioni R, Gore JL, Kessler LG, Lin DW. Influence of publication of US and European prostate cancer screening trials on PSA testing practices. J Natl Cancer Inst. 2011 Mar 16;103(6):520-3. Epub 2011 Feb 28.  PMID: 21357307
PubMed
DOI


Rodriguez H, Tezak Z, Mesri M, Carr SA, Liebler DC, Fisher SJ, Tempst P, Hiltke T, Kessler LG, Kinsinger CR, Philip R, Ransohoff DF, Skates SJ, Regnier FE, Anderson NL, Mansfield E; Workshop Participants. Analytical validation of protein-based multiplex assays: a workshop report by the NCI-FDA interagency oncology task force on molecular diagnostics. Clin Chem. 2010 Feb;56(2):237-43. Epub 2009 Dec 10. Review.  PMID: 20007859
PubMed
DOI


Regnier FE, Skates SJ, Mesri M, Rodriguez H, Tezak Z, Kondratovich MV, Alterman MA, Levin JD, Roscoe D, Reilly E, Callaghan J, Kelm K, Brown D, Philip R, Carr SA, Liebler DC, Fisher SJ, Tempst P, Hiltke T, Kessler LG, Kinsinger CR, Ransohoff DF, Mansfield E, Anderson NL. Protein-based multiplex assays: mock presubmissions to the US Food and Drug Administration. Clin Chem. 2010 Feb;56(2):165-71. Epub 2009 Dec 10.  PMID: 20007858
PubMed
DOI


view books/publications in WorldCat

External Funding (sampling of recent awards from UW SAGE data)

ARRA Multi-Payer Claims Database (“MPCD”) Implementation – University of Washington Subcontract
IPSS Ingenix Public Sector Solutions, Inc.
PI:   Kessler           Dates:    3/19/2012 - 9/15/2013

Consortium Cancer Center Support Grant 2012
Fred Hutchinson Cancer Research Center (FHCRC)
PI:   Bremner           Dates:    1/1/2012 - 12/31/2012

VA Service Agreement 2009
VA Puget Sound Health Care System (VAPSHCS)
PI:   Kessler           Dates:    10/1/2011 - 9/30/2012

Surgical Care and Outcomes Assessment Program Comparative Effectiveness Research Translation Network (SCOAP CERTN)
Agency for Healthcare Research and Quality (AHRQ)
PI:   Flum           Dates:    11/1/2010 - 10/31/2013

VA Service Agreement 2009
VA Puget Sound Health Care System (VAPSHCS)
PI:   Kessler           Dates:    10/1/2010 - 9/30/2011

CER Administrative Supplement- Workforce Development
National Center for Research Resources (NCRR)
PI:   Disis           Dates:    9/30/2010 - 9/29/2011

Back pain Outcomes using Longitudinal Data (BOLD)
Agency for Healthcare Research and Quality (AHRQ)
PI:   Jarvik           Dates:    9/1/2010 - 8/31/2013

ARRA ADVancing Innovative Comparative Effectiveness research-cancer diagnostics-ADVICE
National Institutes of Health (NIH)
PI:   Kessler           Dates:    9/1/2010 - 8/31/2011

ARRA ADVancing Innovative Comparative Effectiveness research-cancer diagnostics-ADVICE
National Institutes of Health (NIH)
PI:   Kessler           Dates:    10/1/2009 - 9/30/2011

VA Service Agreement 2009
VA Puget Sound Health Care System (VAPSHCS)
PI:   Kessler           Dates:    10/1/2009 - 9/30/2010

Projects

National Emphysema Treatment Trial
Collaborating on a cost-effectiveness study of a very controversial surgical treatment for emphysema patients.
CanCORS
Collaborating on studies of outcomes and patterns of care of both colorectal cancer and lung cancer. We are looking into what kinds of treatment certain types of patients receive and how we can improve the process of obtaining the best cancer care.
CISNET
Collaborating on a study focused on the tremendous increase in the rate of prostate cancer incidence during the 1990's. Much of this disease may represent 'overdiagnosis' which is accompanied by significant loss of quality of life in many cases.

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