Nicole D. Urban

Research Professor Emeritus, Health Services


ScD   Harvard University, 1978   (Biostatistics, Health Services Admin)
MS   Harvard University, 1973   (Biostatistics)
BA   Simmons College, 1970   (English Literature)

Contact Info


Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N., MP900
Seattle, WA 98109-1024

campus box:   358080
voice:   206-667-6774
fax:   206-667-7850


Nicole Urban is a Member of the Cancer Prevention Research Program of the Public Health Sciences Division and Program Head of the Gynecologocal Cancer Research Program at the Fred Hutchinson Cancer Research Center. She is also the Scientific Director of the Marsha Rivkin Center for Ovarian Cancer Research. For the past 10 years Dr. Urban has studied ways to improve the use, performance and efficacy of breast and ovarian cancer screening tools. She is particularly interested in the evaluation of markers detectable in serum for use in cancer screening.

Breast/ovarian cancer screening; cost-effectiveness analysis

Schully SD, Carrick DM, Mechanic LE, Srivastava S, Anderson GL, Baron JA, Berg CD, Cullen J, Diamandis EP, Doria-Rose VP, Goddard KA, Hankinson SE, Kushi LH, Larson EB, McShane LM, Schilsky RL, Shak S, Skates SJ, Urban N, Kramer BS, Khoury MJ, Ransohoff DF. Leveraging biospecimen resources for discovery or validation of markers for early cancer detection. J Natl Cancer Inst. 2015 Feb 16;107(4). pii: djv012. doi: 10.1093/jnci/djv012. Print 2015 Apr.  PMID: 25688116

Andersen MR, Thorpe J, Buist DS, Beatty JD, Watabayashi K, Hanson N, Resta R, Chubak J, Urban N. Cancer risk awareness and concern among women with a family history of breast or ovarian cancer. Behav Med. 2014 Jul 25:0. [Epub ahead of print]  PMID: 25062114

Karlan BY, Thorpe J, Watabayashi K, Drescher CW, Palomares M, Daly MB, Paley P, Hillard P, Andersen MR, Anderson G, Drapkin R, Urban N. Use of CA125 and HE4 Serum Markers to Predict Ovarian Cancer in Elevated-Risk Women. Cancer Epidemiol Biomarkers Prev. 2014 Jul;23(7):1383-93. doi: 10.1158/1055-9965.EPI-13-1361. Epub 2014 May 1.  PMID: 24789859    PMCID: PMC4082470

Conner JR, Meserve E, Pizer E, Garber J, Roh M, Urban N, Drescher C, Quade BJ, Muto M, Howitt BE, Pearlman MD, Berkowitz RS, Horowitz N, Crum CP, Feltmate C. Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations. Gynecol Oncol. 2014 Feb;132(2):280-6. doi: 10.1016/j.ygyno.2013.12.009. Epub 2013 Dec 12.  PMID: 24333842    PMCID: PMC3932113

Drescher CW, Shah C, Thorpe J, O'Briant K, Anderson GL, Berg CD, Urban N, McIntosh MW. Longitudinal screening algorithm that incorporates change over time in CA125 levels identifies ovarian cancer earlier than a single-threshold rule. J Clin Oncol. 2013 Jan 20;31(3):387-92. doi: 10.1200/JCO.2012.43.6691. Epub 2012 Dec 17.  PMID: 23248253    PMCID: PMC3732015