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Nicole D. Urban
Research Professor Emeritus

Nicole Urban is a Member of the Cancer Prevention Research Program of the Public Health Sciences Division and Program Head of the Gynecologocal Cancer Research Program at the Fred Hutchinson Cancer Research Center. She is also the Scientific Director of the Marsha Rivkin Center for Ovarian Cancer Research. For the past 10 years Dr. Urban has studied ways to improve the use, performance and efficacy of breast and ovarian cancer screening tools. She is particularly interested in the evaluation of markers detectable in serum for use in cancer screening.

Research Interests:
Breast/ovarian cancer screening; cost-effectiveness analysis

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Contact Information


Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N., MP900
Seattle, WA 98109-1024

campus box:   358080
voice:   206-667-6774
fax:   206-667-7850


ScD   Harvard University, 1978   (Biostatistics, Health Services Admin)
MS   Harvard University, 1973   (Biostatistics)
BA   Simmons College, 1970   (English Literature)

Recent Publications

Conner JR, Meserve E, Pizer E, Garber J, Roh M, Urban N, Drescher C, Quade BJ, Muto M, Howitt BE, Pearlman MD, Berkowitz RS, Horowitz N, Crum CP, Feltmate C. Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations. Gynecol Oncol. 2014 Feb;132(2):280-6. doi: 10.1016/j.ygyno.2013.12.009. Epub 2013 Dec 12.  PMID: 24333842    PMCID: PMC3932113

Urban N, Thorpe J, Karlan BY, McIntosh MW, Palomares MR, Daly MB, Paley P, Drescher CW. Interpretation of Single and Serial Measures of HE4 and CA125 in Asymptomatic Women at High Risk for Ovarian Cancer. Cancer Epidemiol Biomarkers Prev. 2012 Nov;21(11):2087-94. doi: 10.1158/1055-9965.EPI-12-0616. Epub 2012 Sep 7.  PMID: 22962406    PMCID: PMC3493821

Pocobelli G, Chubak J, Hanson N, Drescher C, Resta R, Urban N, Buist DS. Prophylactic oophorectomy rates in relation to a guideline update on referral to genetic counseling. Gynecol Oncol. 2012 Aug;126(2):229-35. doi: 10.1016/j.ygyno.2012.04.046. Epub 2012 May 4.  PMID: 22564716    PMCID: PMC3383401

Drescher CW, Hawley S, Thorpe JD, Marticke S, McIntosh M, Gambhir SS, Urban N. Impact of screening test performance and cost on mortality reduction and cost-effectiveness of multimodal ovarian cancer screening. Cancer Prev Res (Phila). 2012 Aug;5(8):1015-24. Epub 2012 Jul 2.  PMID: 22750949

Schummer M, Drescher C, Forrest R, Gough S, Thorpe J, Hellström I, Hellström KE, Urban N. Evaluation of ovarian cancer remission markers HE4, MMP7 and Mesothelin by comparison to the established marker CA125. Gynecol Oncol. 2012 Apr;125(1):65-9. Epub 2011 Dec 7.  PMID: 22155417    PMCID: PMC3303992


Pacific Ovarian Cancer Research Consortium
Marsha Rivkin Center for Ovarian Cancer Research