• Rachel Adria Katzenellenbogen, MD
    Assistant Professor
    Email: click here

Human papillomavirus (HPV) is the most common sexually transmitted infection, affecting more than 75% of the adult population. HPV is categorized as high-risk or low-risk, based on its association with cancer. Through dysregulation of normal cellular function, high-risk HPV blocks signals for DNA damage, programmed cell death, and cellular arrest, all as a part of its viral life cycle. I am studying the mechanism by which high-risk HPV activates telomerase, and enzyme found normally in stem cells and almost categorically activated in cancers, in order to understand how HPV drives cells to become malignant.

© 2007-2018 Seattle Children's Hospital, Research & Foundation

Webmaster (pedweb@uw.edu)