Student Publications

Adams KN, Takaki K, Connolly LE, Wiedenhoft H, Winglee K, Humbert O, Edelstein PH, Cosma CL, Ramakrishnan L. 2010. Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell. Apr 1;145(1):39-53.

Alaniz RC, Thomas SA, Perez-Melgosa M, Mueller K, Farr AG, Palmiter RD and CB Wilson. 1999. Dopamine b-hydroxylase deficiency impairs cellular immunity. Proc. Natl. Acad. Sci. USA, 96(5):2274-8.

Andersen-Nissen E, Smith KD, Bonneau R, Strong RK, Aderem A. 2007. A conserved surface on Toll-like receptor 5 recognizes bacterial flagelin. J Exp Med. 204(2):393-403.

Smith KD, Andersen-Nissen E, Hayashi F, Strobe K, Bergman MA, Barrett SL, Cookson BT and A Aderem. 2003. Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility. Nature Immunol. (12):1247-53.

Peckham D, Andersen-Nissen E, Finkelman FD, Stunz LL and RF Ashman. 2001. Difference in apoptosis induction between surface IgD and IgM. Int Immunol. (3):285-95.

Alaniz RC, Sandall S, Thomas EK and CB Wilson. 2004. Increased Dendritic Cell Numbers Impair Protective Immunity to Intracellular Bacteria Despite Augmenting Antigen-Specific CD8+ T Lymphocyte Responses. J Immunol, 172: 3725-3735.

Meyer-Bahlburg A, Andrews SF, Yu KO, Porcelli SA, Rawlings DJ. 2008. Characterization of a late transitional
B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J Exp Med.  205(1):155-68.

Schillace RV, Andrews SF, Galligan SG, Burton KA, Starks HJ, Bouwer HG, McKnight GS, Davey MP, Carr DW.  2005.  The role of protein kinase A anchoring via the RII alpha regulatory subunit in the murine immune system.  J Immunol   174(11):6847-53.

Kerns HM, Byu BY, Stirling BV, Sather BD, Astrakhan A, Humblet-Baron S, Liggitt D, Rawlings DJ. 2010. B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinema. Blood. March 18;115(11):2146-2155.

Marathe BM, Prislovsky A, Astrakhan A, Rawlings DJ, Wan JY, Strom TS. 2010. Antiplatelet antibodies in WASP (-) mice correlate with evidence of increased in vivo platelet consumption. Exp Hematol. November;37(11):1353-1363.

Astrakhan A, Ochs HD, Rawlings DJ. 2009. Wiskott-Aldrich Syndrome protein is required for homeostasis and function of invariant NKT cells. J Immunol. June 15;182(12):7370-7380.

Astrakhan A, Omori M, Nguyen T, Becker-Herman S, Iseki M, Aye T, Hudkins K, Dooley J, Farr A, Alpers CE,
Ziegler SF, Rawlings DJ. 2007. Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development. Nature Immunol. 8(5):522-31.

Yu PW, Tabuchi RS, Kato RM, Astrakhan A, Humblet-Baron S, Kipp K, Chae K, Ellmeier W, Witte ON,
Rawlings DJ 2004. Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer. Blood 104(5):1281-90.

Moreno-Garcia ME, Sommer K, Shinohara H, Bandaranayake AD, Kurosaki T, Rawlings DJ. 2010. MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity. Mol Cell Biol. 2010 Feb;30(4):922-34.

Meyer-Bahlburg A, Bandaranayake AD, Andrews SF, Rawlings DJ. 2009. Reduced c-myc expression levels limit follicular mature B cell cycling in response to TLR signals. J Immunol. 2009 Apr 1;182(7):4065-75.

Moreno-Garcia ME, Sommer KM, Bandaranayake AD, Rawlings DJ.  2006.  Proximal signals controlling B-cell antigen receptor mediated NF-kappaB activation.  Adv Exp Med Biol 584:89-106.

Sommer K, Guo B, Pomerantz JL, Bandaranayake AD, Moreno-Garcia ME, Ovechkina YL, Rawlings DJ.  2005.  Phosphorylation of the CARMA1 linker controls NF-kappaB activation.  Immunity 23:561-574.

Wong, P., Barton GM, Forbush KA and AY Rudensky. 2001. Tuning of T cell reactivity by self-peptide/MHC ligands. J.Exp. Med., 193:1179-1188.

Barton GM, Beers C, DeRoos P, Eastman SE, Gomez ME, Forbush KA and AY Rudensky. 2000. Positive selection of self-reactive T cells by specific peptide-MHC class II complexes. Proc Nat Acad Sci USA 99(10):6937-42.

Barton GM and AY Rudensky. 1999. Evaluating peptide repertoires within the context of thymocyte development. Seminars in Immunology, 11:417-422.

Barton, GM and AY Rudensky. 1999. Requirement for Diverse, Low-Abundance Peptides in Positive Selection of T Cells. Science 283:67-70.

Barton GM and AY Rudensky. 1998. An altered invariant chain protein with an antigenic peptide in place of CLIP forms SDS-stable complexes with class II ab dimers and facilitates highly efficient peptide loading. Intl. Immunol. 10:1159-1165.

Volna P, Jarjour J, Baxter S, Roffler SR, Monnat RJ Jr, Stoddard BL, Scharenberg AM. 2007. Flow cytometric analysis of DNA binding and cleavage by cell surface-displayed homing endonucleases. Nucleic Acids Res. Nucleic Acids Res. 35(8):2748-58.

Rudensky A, Beers C.  2006.  Lysosomal cysteine proteases and antigen presentation.  Ernst Schering Res Found Workshop  56:81-95.

Beers C, Burich A, Kleijmeer MJ, Griffith JM, Wong P, Rudensky AY.  2005.  Cathepsin S controls HMC class II-mediated antigen presentation by epithelial cells in vivo.  J Immunol 174(3):1205-12.

Beers C, Honey K, Finks, Fink S, Forbush K, Rudensky A. 2003. Differential regulation of cathepsin S and cathepsin L in interferon gamma-treated macrophages. J Exp Med. 197(2):169-79.

Erickson M, Morkowski S, Lehar S, Gillard G, Beers C, Dooley J, Rubin JS, Rudensky A, Farr AG.  2002.  Regulation of thymic epithelium by keratinocyte growth factor.  Blood  100(9):3269-78.

Honey K, BenlaghaK, Beers C, Forbush K, Teyton L, Kleijmeer MJ, Rudensky AY, Bendelac A. 2002. Thymocyte expression of cathepsin L is essential for NKT cell development. Nat Immunol. 3(11): 1069-74.

Hsieh CS, deRoos P, Honey K, Beers C and AY Rudensky. 2002. A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation. J. Immunol. 168:2618-2625.

Barton GM, Beers C, deRoos P, Eastman SR, Gomez ME, Forbush KA and AY Rudensky. 2002. Positive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes. Proc. Natl. Acad. Sci. USA 99:6937-6942.

Eisenman J, Ahdieh M, Beers C, Brasel K, Kennedy MK, Le T, Bonnert TP, Paxton RJ, Park LS.  2002.  Interleukin-15 interactions with interleukin-15 receptor complexes:  characterization and species specificity.  Cytokine  20(3):121-9.

Honey K, Duff M, Beers C, Maric M, Cresswell P and AY Rudensky. 2001. Cathepsin S regulates expression of cathepsin L and turnover of GILT in B lymphocytes. J. Biol. Chem. 276:22573-8.

He Y-W, Beers C, Deftos ML, Ojala EW and KA Forbush. 2000. Down-regulation of the orphan nuclear receptor RORy t is essential for T lymphocyte maturation. J Immunol 164 (11):5668-74.

Suzuki I, Martin S, Beers C, Boursalian TE and PJ Fink. 2000. Fas ligand costimulates the in vivo proliferation of CD8+ T cells. Proc Natl Acad Sci U S A. 97(4):1707-12.

Blish CA, Dillon SR, Farr AG and PJ Fink. 1999. Anergic CD8+ T cells can persist and function in vivo. J Immunol. 163(1):155-64.

Blish CA, Gallay BJ, Turk GL, Kline KM, Wheat W and PJ Fink. 1999. Chronic modulation of the TCR repertoire in the lymphoid periphery. J Immunol. 162(6):3131-40.

Rice GI, Bond J, Asipu A, Brunette RL, Manfield IW, Carr IM, Fuller JC, Jackson RM, Lamb T, Briggs TA, Ali M, Gornall H, Couthard LR, Aeby A, Attart-Montalto SP, Bertini E, Bodemer C, Brockmann K, Brueton LA, Corry PC, Desguerre I, Fazzi E, Cazorla AG, Gener B, Hamel BCJ, Heiberg A, Hunter M, van der Knaap MS, Kumar R, Lagae L, Landrieu PG, Lourenco CM, Marom D, McDermott MF, van der Merew W, Orcesi S, Prendiville JS, Rasmussen M, Shalev SA, Soler DM, Shinawi M, Spiegel R, Tan TY, Vanderver A, Wakeling EL, Wassmer E, Whittaker E, Lebon P, Stetson DB, Bontrhron DT, Crow YJ. 2009. Mutations involved in Aicardi-Goutie res syndrome implicate SAMHD1 as regulator of the innate immune response. Nature Genetics. Published online June 14, 2009.

Sacha JB, Buechler MB, Newman LP, Reed J, Wallace LT, Friedrich TC, Wilson NA, and Watkins DI. 2010. The Ontogeny of CD8+ T cell epitopes derived from SIVmac239 Rev, Vif, and Vpr. J Virol. Oct.; 84(20):10907-12.

Sacha JB, Giraldo-Vela JP, Buechler MB, Maness NJ, Chung C, Friedrich TC, Wilson NA, and Watkins DI. 2009. Gag-and Nef-specific CD4+ T cells recognize and eliminate SIV-infected macrophages early after infection. Proc Natl Acad Sci USA. Jun; 106(24):9791-6.

Sacha JB, Reynolds MR, Buechler MB, Chung C, Jonas AK, Wallace LT, Weiler AM, Lee W, Piaskowski SM, Soma T, Friedrich TC, Wilson NA, Watkins DI. 2008. Differential antigen presentation kinetics of CD8+ T cell epitopes derived from the same viral protein. J Virol. Sept.; 82(18):9293.8.

Buelow B, Scharenberg AM.  2008. Characterization of parameters required for effective use of tamoxifen-regulated recombination. PLoS ONE. 3(9):e3264.

Buelow B, Song Y, Scharenberg AM. 2008  The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes. J Biol Chem. 283(36):24571-83.

Song Y, Buelow B, Perraud AL, Scharenberg AM.  2008.  Development and validation of a cell-based high-throughput screening assay for TRPM2 channel modulators. J Biomol Screen.  13(1):54-61.

Koth LL, Cambier CJ, Ellwanger A, Solon M, Hou L, Lanier LL, Abram CL, Hamerman JA, Woodruff PG. 2010. DAP12 is required for macrophage recruitment to the lung in response to digarette smoke and chemotaxis toward CCL2. J Immunol. 2010 Jun 1;184(11):6522-8.

Woodruff PG, Ellwanger A, Solon M, Cambier CJ, Pinkerton, KE, Koth, LL. 2010. Alveolar macrophage recruitment and activation by chronic second hand smoke exposure in mice. COPD 2009 April; 6(2):86-94.

Gantner BN, Simmons RM, Canavera SJ, Akira, S. and DM Underhill. 2003. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med. 197(9): 1107-17.

Carson BD, Ziegler SF. 2007. Impaired T cell receptor signaling in Foxp3+ CD4 T cells. Ann NY Acad Sci. 1103:167-78.

Weber SE, Harbetson J. Godebu E, Mros GA, Padrick RC, Carson BD, Ziegler SF, Bradley LM.  2006.  Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo.  J Immunol  176(8):4730-9.

Carson BD*, Lopes JE*, Soper DM*, Ziegler SF. 2006. Insights into transcriptional regulation by FOXP3. Front Biosci. 11:1607-19. * Authors contributed equally to this work.

Walker MR, Carson BD, Nepom GT, Ziegler SF, Buckner JH.  2005.  De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25- cells.  Proc Natl Acad Sci USA 102(11):4103-8.

Polanczyk MJ, Carson BD, Subramanian S, Afentoulis M, Vandenbark AA, Ziegler SF and H Offner. 2004. Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment. J Immunol. 173(4):2227-30.

Ohlen C, Kalos M, Cheng LE, Shur AC, Hong DJ, Carson BD, Kokot NC, Lerner CG, Sather BD, Huseby ES, and PD Greenberg. 2002. CD8(+) T Cell Tolerance to a Tumor-associated Antigen Is Maintained at the Level of Expansion Rather than Effector Function. J Exp Med. 195(11):1407-18.

Troxell CL, Sweezy MA, West RR, Reed KD, Carson BD, Pidoux AL, Cande WZ, McIntosh JR.  2001.  pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.  Mol Biol Cell  12(11):3476-88.

Certo M, Ryi B, Annis J, Garibov M, Jarjour J, Rawlings D, Scharenberg A. 2011. Tracking genome engineering outcome at individual DNA breakpoints. Nature Methods. July 10;8(8):671-6.

Ryo T, Certo M, Caprara MG, Scharenberg AM, Stoddard BL. 2009. Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degredation. Nucleic Acids Res. February; 37(3):877-890.

Jarjour J, West-Foyle H, Certo M, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM. 2009. High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display. Nucleic Acids Res. November; 37(20):6871-6880.

Cheng LE, Ohlen C, Nelson BH and PD Greenberg. 2002. Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death. Proc Natl Acad Sci U S A. 99(5):3001-6.

Blattman JN, Cheng LE, Greenberg PD. 2002.  CD8⁺ T cell responses: it’s all downhill after their prime.  Nat Immunol 3:601–2.

Cheng LE, Greenberg PD. 2002.  Elective delivery of augmented IL–2 signals to responding CD8⁺ T cells increases the size of the acute antiviral response and of the resulting memory T cell pool.  J Immunol 169:4990–7.

Ohlen C, Kalos M, Cheng LE, Shur AC, Hong DJ, Carson BD, Kokot NC, Lerner CG, Sather BD, Huseby ES, and PD Greenberg. 2002. CD8(+) T Cell Tolerance to a Tumor-associated Antigen Is Maintained at the Level of Expansion Rather than Effector Function. J Exp Med. 195(11):1407-18.

Krebs LT, Deftos ML, Bevan MJ, Gridley T 2001. The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway. Dev Biol 238(1): 110-19.

Deftos ML and MJ Bevan. 2000. Notch signaling in T cell development. Curr Opin Immunol. 12:166-72.

He Y-W, Beers C, Deftos ML, Ojala EW, Forbush KA and MJ Bevan. 2000. Down regulation of the orphan nuclear receptor ROR? t is essential for T lymphocyte maturation. J. Immunol. 164:5668-5674.

Deftos M.L., Huang E, Ojala EW, Forbush KA and MJ Bevan. 2000. Notch-1 signalling promotes the maturation of CD4 and CD8 thymocytes. Immunity 13:73-84.

Deftos ML, He Y-W, Ojala EW and MJ Bevan. 1998. Correlating Notch signaling with thymocyte maturation. Immunity 9:777-786.

He YW, Deftos ML, Ojala EW and MJ Bevan. 1998. RORy t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. Immunity 9:797-806.

Eastman S, Deftos M, DeRoos PC, Hsu DH, Teyton L, Braunstein NS, Hackett CJ and AY Rudensky. 1996. A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody. Eur J Immunol. 26:385-93.

Dillon SR, Constantinescu A and MS Schlissel. 2001. Annexin V binds to positively selected B cells. J Immunol 166(1):58-71.

Dillon SR, Mancini M, Rosen A and MS Schlissel. 2000. Annexin V binds to viable B cells and colocalizes with a marker of lipid rafts upon B cell receptor activation. J Immunol. 164:1322-32.

Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, et al. 2000. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 408(6808):57-63

Gross JA, Johnston J, Mudri S, Enselman R, Dillon SR, Madden K, et al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. 2000. Nature 404(6781):995-9.

Blish CA, Dillon SR, Farr AG and PJ Fink. 1999. Anergic CD8+ T cells can persist and function in vivo. J Immunol. 163:155-64.

Han S, Dillon SR, Zheng B, Shimoda M, Schlissel MS and G Kelsoe. 1997. V(D)J recombinase activity in a subset of germinal center B lymphocytes. Science. 278:301-5.

Dillon SR, MacKay VL and PJ Fink. 1995. A functionally compromised intermediate in extrathymic CD8+ T cell deletion. Immunity. 3:321-333.

Dillon SR and PJ Fink. 1995. Thymic selection events mediated by the pre-TCR do not depend upon a limiting ligand. Intl. Immunol. 7:1363-1373.

Dillon SR, Jameson SC and PJ Fink. 1994. V beta 5+ T cell receptors skew toward OVA+H-2Kb recognition. J. Immunol. 152:1790-1801.

Dossett ML, Teague RM, Schmitt TM, Tan X, Cooper LJ, Pinzon C, Greenberg PD. 2009. Adoptive Immunotherapy of Disseminated Leukemia With TCR-transduced, CD8(+) T Cells Expressing a Known Endogenous TCR.
Mol Ther. 2009 Feb 10. [Epub ahead of print]PMID: 19209146 [PubMed - as supplied by publisher] .

Teague RM, Greenberg PD, Fowler C, Huang MZ, Tan X, Morimoto J, Dossett ML, Huseby ES, Ohlén C.  2008.Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor. Immunity. May;28(5):662-74.

Rice J, Dossett ML, Ohlén C, Buchan SL, Kendall TJ, Dunn SN, Stevenson FK, Greenberg PD.  2008. DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire. Eur J Immunol. 38(8):2118-30.

Richman SA, Aggen DH, Dossett ML, Donermeyer DL, Allen PM, Greenberg PD, Kranz DM.  2008. Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments. Mol Immunol. 2008 Oct 27.[Epub ahead of print] PMID: 18962897.

Kuball J, Dossett ML, Wolfl M, Ho WY, Voss RH, Fowler C, Greenberg PD. 2007. Facilitating matched pairing and expression of TCR chains introduced into human T cells. Blood. 109(6):2331-8.

Teague RM, Sather BD, Sacks JA, Huang^, MZ, Dossett ML, Morimoto J, Tan XX, Sutton SE, Cooke MP, Ohlen, C, Greenberg PD.  2006. Interleukin-15 rescues tolerant CD8⁺ T cells for use in adoptive immunotherapy of established tumors.  Nat Med.  12:335-41.

Richman SA, Healan SJ, Webert KS, Donermeyer DL, Dossett ML, Greenberg PD, Allen PM, Kranz DM.  2006.  Devleopment of a novel strategy for engineering high-affinity proteins by yeast display.  Prot Eng Des Sel 19:255-64.

Ho WY, Blattman JN, Dossett ML., Yee C, Greenberg PD.  2003.  Adoptive immunotherapy:  Engineering T cell responses as biologic weapons for tumor mass destruction.  Cancer Cell3:431-7.

Doty RT, Xia D, Nguyen SP, Hathaway TR and DM Willerford. 1999. Promoter element for transcription of unrearranged T-cell receptor beta-chain gene in pro-T cells. Blood 93:3017-25.

Pinchuk LM, Grouard-Vogel G, Magaletti DM, Doty RT, Andres RG and EA Clark. 1999. Isolation and characterization of macaque dendritic cells from CD34(+) bone marrow progenitors. Cell Immunol. 196:34-40.

Doty RT and EA Clark. 1998. Two regions in the CD80 cytoplasmic rail regulate CD80 redistribution and cell costimulation. J Immunol 161:2700-7.

Doty RT and EA Clark. 1996. Subcellular localization of CD80 receptors is dependent on an intact cytoplasmic tail and is required for CD28-dependent T cell costimulation. J. Immunol. 157:3270-3279.

Law CL, Aruffo A, Chandran KA, Doty RT and EA Clark. 1995. Ig domains 1 and 2 of murine CD22 constitute the ligand-binding domain and bind multiple sialylated Ligands expressed on B and T cells. J Immunol. 155:3368-76.

Duggan JM. 2011. Synergistic interactions of TLR2/6 and TLR9 induce a high level of resistance to lung infection in mice. J. Immunol. 186(10):5916-26.

Eddy J, Maizels N. 2008. Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes. Nucleic Acids Res. 36(4):1321-33.

Eddy J, Maizels N.  2006.  Gene function correlates with potential for G4 DNA formation in the human genome.  Nucleic Acids Research 34:3887-3896.

Luke JM, Simon GG, Soderholm J, Errett JS, August JT, Gale M Jr, Hodgson CP, Williams JA. 2011. Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine. Journal of Virology. February;85(3):1370-83.

Fink PJ, Fang CA and GL Turk. 1994. The induction of peripheral tolerance by the chronic activation and deletion CD4+V beta 5+ cells. J Immunol 152:4270-81.

Finch RJ, Fields PE and PD Greenberg. 2001. A transcriptional block in the IL-2 promoter at the -150 AP-1 site in effector CD8+ T cells. J Immunol.166(11):6530-6.

Greenberg PD, Finch RJ, Gavin MA, Kalos M, Lewinsohn DA, Lonergan M, Lord JD, Nelson BH, Ohlen C, Sing AP, Warren EH, Yee C and SR Riddell. 1998. Genetic modification of T-cell clones for therapy of human viral and malignant diseases. Cander J Sci Am. Suppl 1:S100-5.

Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY.  2006.  An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires.  Nat Immunol   7(4):401-10.

Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY.  2005.  Regulatory T cell lineage specification by the forkhead transcription factor foxp3.  Immunity  22(3):329-41.

Fontenot JD, Rudensky AY.  2005.  A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.  Nat Immunol  6(4):331-7.

Fontenot JD, Dooley JL, Farr AG, Rudensky AY.  2005.  Developmental regulation of Foxp3 expression during ontogeny.  J Exp Med   3;202(7):901-6.

Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY.  2005.  A function for interleukin 2 in Foxp3-expressing regulatory T cells.  Nat Immunol   6(11):1142-51.

Fontenot JD and AY Rudensky. 2004. Molecular aspects of regulatory T cell development. Semin Immunol. (2):73-80. Review.

Fontenot JD, Gavin MA and AY Rudensky. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol. Apr;4(4):330-6.

Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson DB, Schroeder L and AA Aderem. 2000. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci USA. 97 (25):13766-71.

Teague RM, Greenberg PD, Fowler C, Huang MZ, Tan X, Morimoto J, Dossett ML, Huseby ES, Ohlén C.  2008.  Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor. Immunity 28(5):662-74.

Kuball J, Dossett ML, Wolfl M, Ho WY, Voss RH, Fowler C, Greenberg PD. 2007. Facilitating matched pairing and expression of TCR chains introduced into human T cells. Blood. 109(6):2331-8.

Friend SL, Hosier S, Nelson A, Foxworthe D, Williams DE and A Farr. 1994. A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells. Exp. Hematol. 22:321-328.

Gallegos AM, Bevan MJ.  2006.  Central tolerance:  good but imperfect.  Immunol Rev 209:290-296.

Gallegos AM, Bevan MJ.  2004.  Driven to autoimmunity:  The NOD mouse.  Cell 117:149-51. 

Gallegos A, Bevan MJ.  2004. Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation.  J. Exp. Med. 200:1039-1049. 

Huang EY, Gallegos AM, Richards SM, Lehar SM, Bevan MJ.  2003.  Surface expression of Notch1 on thymocytes: correlation with the double-negative to double-positive transition.  J Immunol 171(5):2296-304.

Gantner BN, Simmons RM, Underhill DM. 2005. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J. Feb 24.

Underhill DM, Gantner BN.  2004.  Integration of Toll-like receptor and phagocytic signaling for tailored immunity.  Microbes Infect 6(15):1368-1373.

Gantner BN, Simmons RM, Canavera SJ, Akira, S. and DM Underhill. 2003. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med. 197(9): 1107-17.

Norment AM, Bogatzki LY, Gantner BN and MJ Bevan. 2000. Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. J Immunol. 164(2):639-48.

Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, Ocheltree EL, Greenberg PD, Ochs HD, Rudensky AY. 2006. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A. 103(17):6659-64.

Warren EH, Gavin MA, Simpson E, Chandler P, Page DC, Disteche C, Stankey KA, Greenberg PD, Riddell SR. 2000. The human UTY gene encodes a novel HLA-B8-restricted H-Y antigen. J Immunol. 164:2807-14.

Gavin MA and MJ Bevan. 1998. Major histocompatibility complex allele-specific peptide libraries and identification of T-cell memotopes. Methods Mol Biol. 87:235-48.

Ehrmann IE, Ellis PS, Mazeyrat S, Duthie S, Brockdorff N, Mattei MG, Gavin MA, Affara NA, Brown GM, Simpson E, Mitchell MJ, Scott DM. 1998 Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution. Hum Mol Genet 7:1725-37.

Greenberg PD, Finch RJ, Gavin MA, Kalos M, Lewinsohn DA, Lonergan M, Lord JD, Nelson BH, Ohlen C, Sing AP, Warren EH, Yee C, and SR Riddell. 1998. Genetic modification of T-cell clones for therapy of human viral and malignant diseases. Cander J Sci Am. May; 4 Suppl 1:S100-5.

Gavin MA and MJ Bevan. 1995. Increased peptide promiscuity provides a rationale for the lack of N-regions in the neonatal T cell repertoire. Immunity 3:793-800.

Gavin MA, Dere B, Grandea III AG, Hogquist KA, and MJ Bevan. 1994. MHC class I allele specific for peptide libraries: Identification of peptides that mimic an H-Y T cell epitope. Eur. J. Immunol. 24:2124-2133.

Gavin MA, Gilbert MJ, Riddell SR, Greenberg PD and MJ Bevan. 1993. Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I MHC-restricted CTL epitopes. J. Immunol. 151:3971-3980.

Hogquist KA, Gavin MA and MJ Bevan. 1993. Positive selection of CD8+ T cells induced by major histocompatibility complex binging peptides in fetal thymic organ culture. J Exp Med. 177:1469-73.

Hovav AH, Panas MW, Rahman S, Sircar P, Gillard G, Cayabyab MJ, Letvin NL. 2007. Duration of antigen expression in vivo following DNA immunization modifies the magnitude, contraction, and secondary responses of CD8+ T lymphocytes. J Immunol. 179(10):6725-33.

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Updated 8/11