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Transgenic Research Reagents

Knock-out/mutant mice in departmental laboratories

Investigator Knockout/mutant strains maintained
Mike Bevan OT-1 (TCR tg)
P14 (TCR TG)
Ed Clark B6.BL-8 high affinity NP+ BCR Tg
B6.BL-8 low affinity NP+ BCR Tg
B10.BR-H2k H2-T18a/SgSnJ
B6.BAFF-Receptor KO
B6.Bam-32 KO
B6.Gp91 KO
B6.Bam-32/Gp91 Double KO
B6.Bim KO
B6.Caspase-6 KO
B6.CD11c-DTR
B6.CD22 KO
B6.CD22 KO/BL-8 high affinity NP+ Tg
B6.CD22 KO/BL-8 low affinity NP+ Tg
B6.CD40 KO
B6.Fcerg1 Tg
B6.GADS KO
B6.BDCA-2 Tg
B6.MHC II KO
B6.Nos-2 KO
B6.OT-I
B6.OT-II
B6.TCR KO
B6.VDJ9k5


Pam Fink B6 1pr
floxed Fas
dLCK-Cre Tg
CD4 KO on a B6 background
IAb KO
mBcl-2 Tg (expressed in T cells)
MTV negative wild-derived mice
floxed Rag
Rosa-YFP(stop) Cre reporter
CD19 Cre knock in
FasL KO
RIPmOVA Tg
Plt B6 mice
TCRa KO
TCRbd KO
Bim KO
IL-7Ra Tg
Ly5 congenic B6
RAG2p-GFP Tg reporter mice on B6 background
TCRTg B6: OT-1, OT-II, SMARTA, P14

 

Michael Gale

C57BL6
Caspase-1 KO
FoxP3-DTR KO
IFNb yfp (MOB) KO
IFN-IR KO
Ikbke (Ikkepsilon) KO
IKKgamma (NEMO)
IL-12 Rb2 KO
IPS-1 KO
IPS-1 WT
LGP2 KO
LGP2 KO x IFN-IR KO (in progress)
MDA5 KO
MyD88 KO
P58
RIG-I KO
RIG-I WT
RIG-I KO x MDA5 KO (in progress)
STI KO
STI KO x IFNb yfp KO (in progress)
STI KO x MyD88 KO (in progress)
Sting KO
Sting WT
Sting KO x STI KO (in progress)
Tbet KO
TLR3 KO
TNK-1 (Kos-1) KO

 

Joan Goverman Rag1-1- on H-2u & H-2b *
Ca -1- on H-2u
CD4-1- on H-2u
MBP-1-on H-2u, H-2h, H2d
MBP TCR tg

al in K wing except * - modified SPF 6th floor


Dan Stetson IFNAR1 KO Ly5.1
TCRa KO
uMT KO
MyD88 KO B6
RAG2 KO
MX-Cre
Rosa26-eYFP floxed reporter
B6.Nba2
IRF3 KO (permission required from Taniguchi)
BALB/c

 

 

updated November 2009

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