September 11

Ft. Worden Conference Center, Pt. Townsend, WA

Steven Reiner, MD
Professor, Department of Medicine, Division of Infectious Diseases, Abramson Family Cancer Research Institute, University of Pennsylvania
"Specifying the T cell fates required for immunity"

Research Interests: Host response to infectious diseases; effector and memory lymphocyte differentiation; gene silencing, chromatin structure and DNA methylation

Mitchell Kronenberg, PhD
President and Scientific Director, La Jolla Institute for Allergy and Immunology
"Innate like responses to microbes by NKT cells"

Research Interests: T cell response to glycolipid antigens

Andrea Cooper, PhD
Associate Member, Trudeau Institute
"IL-12 and tuberculosis: An old story"

Research Interests: Initiation of cellular responses in the lung; control of inflammatory responses in the lung; chronic infection in the elderly

Michael Karin, PhD
Professor, Department of Pharmacology, UC San Diego
"Tracking the road from inflammation to cancer: The critical role of IKK"

Research Interests: Gene Expression, Signal Transduction, Transcription Factors, Oncogenes, Protein Kinases

Paolo Casali, MD
Donald L. Bren Professor of Medicine, Molecular Biology & Biochemistry, and Director, Center for Immunology Research Centers and Institutes, UC Irvine
"Regulation of somatic hypermutation and class switch DNA recombination"

Research Interests: Molecular Immunology and Genetics

Barry Sleckman, MD, PhD
Associate Professor, Department of Pathology and Immunology, Washington University
"Lymphocyte development: Taking cues from damaged DNA"

Research Interests: T cell development and lineage determination

Alexander Tarakhovsky, PhD

SEMINAR CANCELLED

Michael Croft, PhD
Member, Molecular Immunology Division, La Jolla Institute for Allergy & Immunology
"OX40 antagonism of T cell tolerance"

Research Interests: cell signaling in allergic inflammation and the costimulatory interactions during the aging process

OPEN

Klaus Rajewsky, MD
Senior Investigator, CBR Institute for Biomedical Research, Fred S. Rosen Professor, Department of Pediatrics, andProfessor, Department of Pathology, Harvard University
"MicroRNA control in lymphocytes"

Research Interests: B lymphocyte development

Michael Carroll, PhD
Senior Investigator, CBR Institute for Biomedical Research & Professor, Departments of Pediatrics and Pathology, Harvard University
"Innate immunity in B cell tolerance"

Research Interests: the role of the complement system in innate and acquired immunity

Albert Bendelac, MD, PhD
HHMI Investigator and Professor, Department of Pathology, University of Chicago
"NKT cells: From development to function"

Research Interests: CD1-mediated antigen presentation; type I diabetes

Mark Jutila, PhD
Professor, Veterinary Molecular Biology, Montana State University
"Enhancement of innate immunity: Targeting yó cells and macrophages"

Research Interests: Molecular events that control leukocyte entry into sites of acute and chronic inflammation; Analyses of gamma/delta T cells in the context of host immune responses and developmental immunology

David Woodland, PhD
President and Director, The Trudeau Institute
"Chemokine regulation of CD8+ T cell responses to respiratory virus infections"

Research Interests: how cellular immune responses fight viral and bacterial infections of the lung

Mark Davis, PhD
HHMI Investigator and Avery Professor, Department of Microbiology & Immunology, Director, Institute of Immunity, Transplantation & Infection, Stanford University

RUSSELL AND RAE WEISER ENDOWED LECTURE IN IMMUNOLOGY
"Thirty-six views of T cell recognition"

Research Interests: the molecular basis of T and B lymphocyte recognition; the control of differentiation and functional responses in these cells

Vishva Dixit, MD
Vice President & Staff Scientist, Molecular Oncology, Genentech
"Regulation of inflammation by ubiquitin modification of signaling components"

Research Interests: characteristics of the apoptotic pathway

Jenny Ting, PhD
Alumni Distinguished Professor, Department of Microbiology & Immunology, Lineberger Comprehensive Cancer Center, UNC Chapel Hill
"Application of systems biology to identify new innate and adaptive immune pathways"

Research Interests: innate immunity, dendritic cell function, oxidative-stress, apoptosis, signal transduction, gene discovery, functional genomics and proteomics, gene regulation, molecular immunology, neuro-inflammation and microglial cells

Sankar Ghosh, PhD
Professor, Department of Immunobiology and Department of Molecular Biophysics & Chemistry, Yale University
"NF-kB: a mediator of immune and inflammatory responses"

Research Interests: Regulation and function of NF- kB and related proteins; pleiotropic mediators of inducible gene expression

May 5

OPEN

Stephen Smale, PhD
HHMI Investigator and Professor,Department of Microbiology, Immunology & Molecular Genetics, UCLA
"Pioneer transcription factor interactions in embryonic and induced pluripotent stem cells"

Research Interests: Transcriptional regulation in the immune system