Charter Statement
Established in 1989, the Imaging Research Laboratory is a multidisciplinary team committed to advancing tomographic medical imaging which uses ionizing radiation. In collaboration with clinical, academic, and industrial partners, the IRL addresses all levels of this challenge through the following aims: to develop innovative instrumentation and methods, to construct analysis and evaluation tools, to serve as a training facility for new imaging scientists, and to translate developments to preclinical and clinical applications for improved healthcare.
Current Research Focus Areas
- Enabling Ultra-Low Dose PET/CT Imaging
- Imaging of Myocardial Blood Flow PET and SPECT Scanner
- Simulation Packages
- Quantitative PET/CT and SPECT/CT Imaging
- Detector and Timing Electronics and Data Acquisition Systems
- Imaging Integration with Radiation Treatment Planning
- Novel PET system designs for preclinical and application-specific imaging
- Dedicated Breast PET coupled to X-RAY Mammography (Breast PET/X)
- Cancer Imaging Research Protocols and Clinical Trials Using PET/CT
Current Members
Faculty
Paul Kinahan, PhD, FIEEE
Professor & Director
kinahan@uw.edu
Robert Miyaoka, PhD
Professor
rmiyaoka@uw.edu
Neal Paragas, PhD
Professor
paragas@uw.edu
Staff
Wei Wu (Vivi), MD
Research Fellow
vivi2011@uw.edu
William Hunter, PhD
Lab Chief/Research Scientist
wcjh@uw.edu
Mark Muzi, MS
Director of Image Analysis
muzi@uw.edu
J Peter Muzi, BS
Research Scientist
jpmuzi@uw.edu
Darshini Vijayakumar, BS
Research Scientist
dvijay26@uw.edu
Darrin Byrd, MS
Research Scientist
dbyrd2@uw.edu
Guest Members
Ali Nabipoor, MD
Research Fellow
sanpa@uw.edu
Negar Firoozeh, MD
Postdoc
nfirooze@uw.edu
Arash Mahdavi, MD
Postdoc
amahdavi@uw.edu
Lambert Leong, PhD
Postdoc Fellow
laleong@uw.edu
Students
Zihan Li
Graduate Student
zhanli@uw.edu
Yun-Huan Lyu
Graduate Student
yhlyu@uw.edu
Jackson Hayward
Intern
jch1013@uw.edu
Papers
- Timing, Energy, and 3-D Spatial Resolution of the BING PET Detector Module
Published 2023 – IEEE Transactions on Radiation and Plasma Medical Sciences
- Crystal Area Segmentation for a Scintillation Detector based on Convolutional Neural Network
Published 2020 – 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
- Abstract P2-03-25: Pilot study to evaluate circulating tumor DNA (ctDNA) to PET/CT imaging using 18F-Fluorodeoxyglucose (FDG) and 18F-Fluoroestradiol (FES) PET/CT imaging as biomarkers in patients with metastatic breast cancer
Published 2023 – Cancer Research
- Semi-automated extraction of research topics and trends from NCI funding in radiological sciences from 2000-2020
Published 2023 – ArXiv
- Evaluation of Apparent Diffusion Coefficient Repeatability and Reproducibility for Preclinical MRIs Using Standardized Procedures and a Diffusion-Weighted Imaging Phantom
Published 2023 – Tomography
- Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection
Published 2022 – Cell Reports
- Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression
Published 2022 – Viruses
- Snapshots of nascent RNA reveal cell- and stimulus-specific responses to acute kidney injury
Published 2022 – JCI Insight