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2014

H. Tashima, T. Yamaya, and P. E. Kinahan, “An OpenPET scanner with bridged detectors to compensate for incomplete data,” Phys. Med. Biol., vol. 59, no. 20, pp. 6175–6193, Sep. 2014.

SR Bowen, LA Pierce, AM Alessio et al.; "Assessment of patient selection criteria for quantitative imaging with respiratory-gated positron emission tomography," J. Med. Imag., 1(2), 026001 (2014). link

L A Pierce, W C J Hunter, D R Haynor, L R MacDonald, P E Kinahan, R S Miyaoka; "Multiplexing strategies for monolithic crystal PET detector modules," Phys. Med. Biol. 59 5347 (2014). link

Phillips GS, Stanescu AL, Alessio AM. Relationships of Pediatric Anthropometrics for CT Protocol Selection. American Journal of Roentgenology. 2014;203: W85-W91. link

Mountz JM, Yankeelov TE, Rubin DL, Buatti JM, Erickson BJ, Fennessy F, Gillies RJ, Huang W, Jacobs MA, Kinahan PE, Laymon, CM, Linden HM, Mankoff DA, Schwartz LH, Shim H, Wahl RL. Letter to Cancer Center Directors: Progress in Quantitative Imaging As a Means to Predict and/or Measure Tumor Response in Cancer Therapy Trials. Journal of Clinical Oncology, (ePub ahead of print) May 2014.

Obuchowski NA, Reeves AP, Huang EP, Wang X-F, Buckler AJ, Kim HJ, Barnhart HX, Jackson EF, Giger ML, Pennello G, Toledano AY, Kalpathy-Cramer J, Apanasovich TV, Kinahan PE, Myers KJ, Goldgof DB, Barboriak DP, Gillies RJ, Schwartz LH, Sullivan DC. Quantitative imaging biomarkers: A review of statistical methods for computer algorithm comparisons. Stat Methods Med Res, Published online before print June 11, 2014.

Bindschadler, Modgil, Branch, La Riviere, Alessio, "Comparison of Blood Flow Models and Acquisitions for Quantitative Myocardial Perfusion Estimation from Dynamic CT," Physics in Medicine and Biology, vol 59:7, 2014.

Doot RK, Pierce LA II, Byrd D, Elston B, Allberg KC, Kinahan PE. Biases in multicenter longitudinal PET standardized uptake value measurements. Translational Oncology Vol. 7, pp. 48-54, 2014.

Harrison RL, Elston BF, Doot RK, Lewellen TK, Mankoff DA, Kinahan PE. A Virtual Clinical Trial of FDG-PET Imaging of Breast Cancer: Effect of Variability on Response Assessment. Translational Oncology Vol. 7, pp. 138-146, 2014.

Chenevert TL, Malyarenko DI, Newitt D, Li X, Jayatilake M, Tudorica A, Fedorov A, Kikinis R, Liu T, Muzi M, Oborski MJ, Laymon CM, Li X, Yankeelov T, Kalpathy-Cramer J, Mountz JM, Kinahan PE, Rubin DL, Fennessy F, Huang W, Hylton N, Ross BD. Errors in Quantitative Image Analysis due to Platform-Dependent Image Scaling. Translational Oncology Vol. 7, pp. 65-71, 2014.

Kalpathy-Cramer J, Freymann JB, Kirby JS, Kinahan PE, Prior FW. Quantitative Imaging Network: Data Sharing and Competitive Algorithm Validation Leveraging The Cancer Imaging Archive. Translational Oncology Vol. 7, pp. 147-152, 2014.

Huang W, Li X, Chen Y, Li X, Chang MC, Oborski MJ, Malyarenko DI, Muzi M, Jajamovich GH, Fedorov A, Tudorica A, Gupta SN, Laymon CM, Marro KI, Dyvorne HA, Miller JP, Barbodiak DP, Chenevert TL, Yankeelov T, Mountz JM, Kinahan PE, Kikinis R, Taouli B, Fennessy F, Kalpathy-Cramer J. Variations of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Evaluation of Breast Cancer Therapy Response: A Multicenter Data Analysis Challenge. Translational Oncology Vol. 7, pp. 153-166, 2014.

Lewellen, T.K., DeWitt, D., Miyaoka, R.S., Hauck, S.: “A Building Block for Nuclear Medicine Imaging Systems Data Acqusition”, IEEE Tran Nuc Sci 61, pp. 79-87 (2014). PMID PMC3833631

Huang EP, Wang XF, Choudhury KR, McShane LM, Gonen M, Ye J, Buckler AJ, Kinahan P, Reeves AP, Jackson EF, Guimaraes AR, Zahlmann G. Meta-Analysis of the Technical Performance of an Imaging Assay: Guidelines and Statistical Methodology. Statistical Methods in Medical Research. Accepted 2014.

Xia T, Alessio AM, Kinahan PE. Dual energy CT for attenuation correction with PET∕CT. Medical Physics, vol. 41, no. 1, p. 012501, Jan. 2014.

Wang S, Bowen SR, Chaovalitwongse WA, Sandison GA, Grabowski TJ, and Kinahan PE, Respiratory trace feature analysis for the prediction of respiratory-gated PET quantification. Phys. Med. Biol., vol. 59, no. 4, pp. 1027–1045, Feb. 2014

 

2013

T. J. Bradshaw, S. R. Bowen, N. Jallow, L. Forrest, and R. Jeraj, “Intratumor correlations of FDG, FLT, and Cu-ATSM PET in canine sarcoma and carcinoma tumors: implications for dose painting,” J Nucl Med (in press) (2013).

R Jeraj, SR Bowen, N Jallow, MJ Nyflot, M Vanderhoek. Molecular Imaging in Radiation Oncology. In J Van Dyk Modern Technologies of Radiation Therapy, Volume 3. 2013.

MJ Nyflot, N Cao, J Meyer, EC Ford. Improved accuracy for noncoplanar radiotherapy: an EPID-based method for sub-millimeter alignment of accelerator table rotation about MV isocenter. J Appl Clin Med Phys. In press.

W.P. Shuman , D.E. Green, J.M. Busey, O Kolokythas, L.M. Mitsumori, K.M. Koprowicz, J-B Thibault, J. Hsieh, A.M. Alessio, P.E. Kinahan, Model Based Iterative Reconstruction (MBIR) versus Adaptive Statistical Iterative Reconstruction (ASIR) and Filtered Back Projection (FBP) in Low Radiation Dose 64 Channel Liver CT: Focal Lesion Detection, Lesion Conspicuity, and Image Noise. AJR, 200(5) 1071-1076, 2013. link

W.C.J.Hunter, H.H. Barrett, J.P. Muzi, W. McDougald, L.R. MacDonald, R.S. Miyaoka, T.K. Lewellen, SCOUT: a fast Monte-Carlo modeling tool of scintillation camera, Phys. Med. Biol., Vol 58, pp. 3581–3598, (2013), link.

X. Li, A.M. Alessio, T.H. Burnett, T.K. Lewellen, R.S. Miyaoka, Performance Evaluation of Small Animal PET Scanners With Different System Designs, Nuclear Science, IEEE Transactions on PP. 1-8. 2013. link .

S.M. Kraynik, R.S. Miyaoka, J.A. Beavo, PDE3 and PDE4 isozyme selective inhibitors are both required for synergistic activation of brown adipose tissue, Mol Pharmacol 2013. link .

A. Alessio, J. Bassingthwaighte, S. Glenny, J. Caldwell, Validation of an Axially-Distributed Model for Quantification of Myocardial Blood Flow using 13N-Ammonia PET Journal of Nuclear Cardiology, vol 20:1, pp 64-75, 2013.

A. Alessio and LR MacDonald, Quantitative Material Characterization from Multi-Energy Photon Counting CT, Med. Phys., vol 40:3, 2013.

SA. Padia, A. Alessio, Kwan, Lewis, Vaidya, Minoshima, "Comparison of PET and Bremsstrahlung imaging to detect particle distribution in patients undergoing Yttrium-90 radioembolization for large hepatocellular carcinomas or associated portal vein thrombosis" Journal of Vascular and Interventional Radiology, Vol 24:8, pp 1147-1153, 2013.

Khorsand, Song, Swanson, A. Alessio, Redding, Waldhausen, “Iatrogenic Radiation Exposure to Patients With Early Onset Spine and Chest Wall Deformitie" Spine, vol 38:17, pp 1108-14, 2013.

MacDonald LR, Hunter WCJ, Kinahan PE, Miyaoka RS, Effects of Detector Thickness on Geometric Sensitivity and Event Positioning Errors in the Rectangular PET/X Scanner. IEEE TNS v60(5):3242-3252, 2013 2013. link.

Makris NE, Huisman MC, Kinahan PE, Lammertsma AA, Boellaard R. Evaluation of strategies towards harmonization of FDG PET/CT studies in multi-centre trials: comparison of scanner validation phantoms and data analysis procedures. Eur J Nucl Med Mol Imaging 2013 Oct;40(10):1507-15. doi: 10.1007/s00259-013-2465-0. Epub 2013 Jun 11. link.

Kurland BF, Doot RK, Linden HM, Mankoff DA, Kinahan PE. Multicenter trials using FDG PET to predict chemotherapy response: Effects of differential measurement error and bias on power calculations for unselected and enrichment designs. Clinical Trials, 2013.

2012

S. R. Bowen, R. J. Chappell, S. M. Bentzen, M. A. Deveau, L. Forrest and R. Jeraj, “Spatially resolved multivariate regression of pre-treatment FDG, FLT, and Cu-ATSM PET from post-treatment FDG PET: an exploratory study,” Radiother Onc 105, 41-48 (2012).

MJ Nyflot, PM Harari, S Yip, SB Perlman, R Jeraj: Correlation of PET images of metabolism, proliferation and hypoxia to characterize tumor phenotype in patients with cancer of the oropharynx. Radiother Oncol 2012, 105:36-40.

W.C.J. Hunter, H.H. Barrett, T.K. Lewellen, R.S. Miyaoka, Multiple-Hit Parameter Estimation in Monolithic Detectors, IEEE Trans. Med. Imag., Vol 32, Issue 2, pp. 32–337, (2012), link.

R.K. Doot, B.F. Kurland, P.E. Kinahan, D.A. Mankoff, Design Considerations for using PET as a Response Measure in Single Site and Multicenter Clinical Trials, ACADEMIC RADIOLOGY 19. 184-190. 2012. link .

J.M. Marzluff, R. Miyaoka, S. Minoshima, D.J. Cross, Brain imaging reveals neuronal circuitry underlying the crow’s perception of human faces, Proceedings of the National Academy of Sciences 2012. link .

S. Bowen, M. Nyflot, M. Gensheimer, K.R. Hendrickson, P. Kinahan, G. Sandison, S. Patel, Challenges and opportunities in patient-specific, motion-managed and PET/CT-guided radiation therapy of lung cancer: review and perspective, Clinical and Translational Medicine 1. 18. 2012. link .

M. Abella, A.M. Alessio, D.A. Mankoff, L.R. MacDonald, J.J. Vaquero, M. Desco, P.E. Kinahan, Accuracy of CT-based attenuation correction in PET/CT bone imaging, Phys Med Biol 57. 2477-2490. 2012. link .

E.O. Aboagye, F.J. Gilbert, I.N. Fleming, A.J. Beer, V.J. Cunningham, P.K. Marsden, D. Visvikis, A.D. Gee, A.M. Groves, L.M. Kenny, G.J. Cook, P.E. Kinahan, M. Myers, L. Clarke, Recommendations for measurement of tumour vascularity with positron emission tomography in early phase clinical trials, Eur Radiol 22. 1465-1478. 2012. link .

T. Chapman, J.O. Swanson, G.S. Phillips, M.T. Parisi, A.M. Alessio, Pediatric chest CT radiation dose reduction: protocol refinement based on noise injection for pulmonary nodule detection accuracy, Clinical imaging Clinical imaging Clin Imaging 2012. link .

R.K. Doot, T. Thompson, B.E. Greer, K.C. Allberg, H.M. Linden, D.A. Mankoff, P.E. Kinahan, Early experiences in establishing a regional quantitative imaging network for PET/CT clinical trials, Magn Reson Imaging 2012. link .

S. Gu, G. Chakraborty, K. Champley, A.M. Alessio, J. Claridge, R. Rockne, M. Muzi, K.A. Krohn, A.M. Spence, E.C.J. Alvord, A.R. Anderson, P.E. Kinahan, K.R. Swanson, Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images, Math Med Biol 29. 31-48. 2012. link .

W. Kerwin, A. Alessio, M. Ferguson, T. Hatsukami, J. Caldwell, R. Miyaoka, T. Kohler, C. Yuan, High-resolution [18]fluorodeoxyglucose-positron emission tomography and coregistered magnetic resonance imaging of atherosclerotic plaque from a patient undergoing carotid endarterectomy, Circ Cardiovasc Imaging 5. 683-684. 2012. link .

X.L. Li, W.C.J. Hunter, T.K. Lewellen, R.S. Miyaoka, Use of Cramer-Rao Lower Bound for Performance Evaluation of Different Monolithic Crystal PET Detector Designs, Ieee T Nucl Sci 59. 3-12. 2012. link .

L.R. Macdonald, C.L. Wang, M. Eissa, D. Haseley, M.M. Kelly, F. Liu, J.R. Parikh, J.D. Beatty, J.V. Rogers, Positron emission mammography (PEM): effect of activity concentration, object size, and object contrast on phantom lesion detection, Med Phys 39. 6499-6508. 2012. link .

M. Muzi, F. O'Sullivan, D.A. Mankoff, R.K. Doot, L.A. Pierce, B.F. Kurland, H.M. Linden, P.E. Kinahan, Quantitative assessment of dynamic PET imaging data in cancer imaging, Magn Reson Imaging 2012. link .

L. Pierce, R. Miyaoka, T. Lewellen, A. Alessio, P. Kinahan, Detector Position Estimation for PET Scanners, Nucl Instrum Methods Phys Res A 677. 74-79. 2012. link .

D.A. Plotnik, C. Asher, S.K. Chu, R.S. Miyaoka, G.G. Garwin, B.W. Johnson, T. Li, K.A. Krohn, J.L. Schwartz, Levels of human equilibrative nucleoside transporter-1 are higher in proliferating regions of A549 tumor cells grown as tumor xenografts in vivo, Nucl Med Biol 39. 1161-1166. 2012. link .

Swanson, J., A. Alessio, T. Chapman, Estimated additional lifetime risk of cancer attributable to diagnostic CT in a pediatric bone marrow transplant cohort: Experience at a single academic institution, Open Journal of Clinical Diagnostics 2. 4-9. 2012. link .

T. Xia, A.M. Alessio, B. De Man, R. Manjeshwar, E. Asma, P.E. Kinahan, Ultra-low dose CT attenuation correction for PET/CT, PHYSICS IN MEDICINE AND BIOLOGY 57. 309-328. 2012. link .

2011

S. R. Bowen, A. J. van der Kogel, M. Nordsmark, S. M. Bentzen and R. Jeraj, “Characterization of PET hypoxia tracer uptake and tissue oxygenation via electrochemical modeling,” Nucl Med Biol 38, 771-780 (2011).

K.M. Champley, L.R. MacDonald, T.K. Lewellen, R.S. Miyaoka, P.E. Kinahan, DOI-based reconstruction algorithms for a compact breast PET scanner, MEDICAL PHYSICS 38. 1660-1671. 2011. link .

S. Tong, A.M. Alessio, P.E. Kinahan, Image reconstruction for PET/CT scanners: past achievements and future challenges, Imaging Med 2. 529-545. 2010. link .

C. Liu, A.M. Alessio, P.E. Kinahan, Respiratory motion correction for quantitative PET/CT using all detected events with internal-external motion correlation, MEDICAL PHYSICS 38. 2715-2723. 2011. link .

C.M. Lockhart, L.R. MacDonald, A.M. Alessio, W.A. McDougald, R.K. Doot, P.E. Kinahan, Quantifying and Reducing the Effect of Calibration Error on Variability of PET/CT Standardized Uptake Value Measurements, JOURNAL OF NUCLEAR MEDICINE 52. 218-224. 2011. link .

L.R. MacDonald, S. Kohlmyer, C. Liu, T.K. Lewellen, P.E. Kinahan, Effects of MR surface coils on PET quantification, MEDICAL PHYSICS 38. 2948-2956. 2011. link .

R.S. Miyaoka, X.L. Li, W. Hunter, L.A. Pierce, W. McDougald, P.E. Kinahan, T.K. Lewellen, Resolution Properties of a Prototype Continuous Miniature Crystal Element (cMiCE) Scanner, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 58. 2244-2249. 2011. link .

W.C.J. Hunter, H.H. Barrett, R.S. Miyaoka, T.K. Lewellen, Multiple-hit parameter estimation in monolithic detectors, Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE 2224-2229. 2011. link .

S. Tong, A.M. Alessio, P.E. Kinahan, H. Liu, P. Shi, A robust state-space kinetics-guided framework for dynamic PET image reconstruction, PHYSICS IN MEDICINE AND BIOLOGY 56. 2481-2498. 2011. link .

S. Tong, A.M. Alessio, K. Thielemans, C. Stearns, S. Ross, P.E. Kinahan, Properties and Mitigation of Edge Artifacts in PSF-Based PET Reconstruction, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 58. 2264-2275. 2011. link .

R.S. Miyaoka, X.L. Li, W. Hunter, L.A. Pierce, W. McDougald, P.E. Kinahan, T.K. Lewellen, Resolution Properties of a Prototype Continuous Miniature Crystal Element (cMiCE) Scanner, Ieee T Nucl Sci 58. 2244-2249. 2011. link .

X.L. Li, C. Lockhart, T.K. Lewellen, R.S. Miyaoka, Study of PET Detector Performance With Varying SiPM Parameters and Readout Schemes, Ieee T Nucl Sci 58. 590-596. 2011. link .

N.G. Johnson-Williams, R.S. Miyaoka, X.L. Li, T.K. Lewellen, S. Hauck, Design of a Real Time FPGA-Based Three Dimensional Positioning Algorithm, Ieee T Nucl Sci 58. 26-33. 2011. link .

L. Xiaoli, C. Lockhart, T.K. Lewellen, R.S. Miyaoka, Study of PET Detector Performance With Varying SiPM Parameters and Readout Schemes, Nuclear Science, IEEE Transactions on 58. 590-596. 2011. link .

A.M. Alessio, M. Sammer, G.S. Phillips, V. Manchanda, B.C. Mohr, M.T. Parisi, Evaluation of optimal acquisition duration or injected activity for pediatric 18F-FDG PET/CT, J Nucl Med 52. 1028-1034. 2011. link .

L.R. MacDonald, R.L. Harrison, A.M. Alessio, W.C. Hunter, T.K. Lewellen, P.E. Kinahan, Effective count rates for PET scanners with reduced and extended axial field of view, Phys Med Biol 56. 3629-3643. 2011. link .

M.B. Sammer, B.L. Shulkin, A. Alessio, M.T. Parisi, Role of limited whole-body PET/CT in pediatric lymphoma, AJR Am J Roentgenol 196. 1047-1055. 2011. link .

C. Liu, A.M. Alessio, P.E. Kinahan, Respiratory motion correction for quantitative PET/CT using all detected events with internal-external motion correlation, Med Phys 38. 2715-2723. 2011. link .

J.L. Busch, A.M. Alessio, J.H. Caldwell, M. Gupta, S. Mao, J. Kadakia, W. Shuman, M.J. Budoff, K.R. Branch, Myocardial hypo-enhancement on resting computed tomography angiography images accurately identifies myocardial hypoperfusion, J Cardiovasc Comput Tomogr 5. 412-420. 2011. link .

2010

A.M. Alessio, C.W. Stearns, S. Tong, S.G. Ross, S. Kohlmyer, A. Ganin, P.E. Kinahan, Application and Evaluation of a Measured Spatially Variant System Model for PET Image Reconstruction, IEEE TRANSACTIONS ON MEDICAL IMAGING 29. 938-949. 2010. link .

A.M. Alessio, E. Butterworth, J.H. Caldwell, J.B. Bassingthwaighte, Quantitative imaging of coronary blood flow, Nano Rev 1. 2010. link .

A.M. Alessio, P.E. Kinahan, K.M. Champley, J.H. Caldwell, Attenuation-emission alignment in cardiac PET/CT based on consistency conditions, MEDICAL PHYSICS 37. 1191-1200. 2010. link .

D.L. Chen, P.E. Kinahan, Multimodality Molecular Imaging of the Lung, JOURNAL OF MAGNETIC RESONANCE IMAGING 32. 1409-1420. 2010. link .

K.M. Champley, R.R. Raylman, P.E. Kinahan, Advancements to the planogram frequency-distance rebinning algorithm, INVERSE PROBLEMS 26. 045008. 2010. link .

R.K. Doot, J.S. Scheuermann, P.E. Christian, J.S. Karp, P.E. Kinahan, Instrumentation factors affecting variance and bias of quantifying tracer uptake with PET/CT, MEDICAL PHYSICS 37. 6035-6046. 2010. link .

F.H. Fahey, P.E. Kinahan, R.K. Doot, M. Kocak, H. Thurston, T.Y. Poussaint, Variability in PET quantitation within a multicenter consortium, MEDICAL PHYSICS 37. 3660-3666. 2010. link .

P.E. Kinahan, J.W. Fletcher, Positron Emission Tomography-Computed Tomography Standardized Uptake Values in Clinical Practice and Assessing Response to Therapy, SEMINARS IN ULTRASOUND CT AND MRI 31. 496-505. 2010. link .

C. Liu, A. Alessio, L. Pierce, K. Thielemans, S. Wollenweber, A. Ganin, P. Kinahan, Quiescent period respiratory gating for PET/CT, MEDICAL PHYSICS 37. 5037-5043. 2010. link .

K.R. Swanson, S. Gu, G. Chakraborty, A. Alessio, J. Claridge, R.C. Rockne, M. Muzi, K.A. Krohn, A.M. Spence, E.C. Alvord, A.R. Anderson, P. Kinahan, IN SILICO PET IMAGING: FROM ANATOMIC GLIOMA GROWTH DYNAMICS TO METABOLIC TUMOR ACTIVITY VIA BIO-MATHEMATICAL MODELING, NEURO-ONCOLOGY 12. 118-118. 2010. link .

R.S. Miyaoka, X.L. Li, C. Lockhart, T.K. Lewellen, Comparison of Detector Intrinsic Spatial Resolution Characteristics for Sensor on the Entrance Surface and Conventional Readout Designs, Ieee T Nucl Sci 57. 990-997. 2010. link .

S. Tong, A.M. Alessio, P.E. Kinahan, Noise and signal properties in PSF-based fully 3D PET image reconstruction: an experimental evaluation, PHYSICS IN MEDICINE AND BIOLOGY 55. 1453-1473. 2010. link .

R.S. Miyaoka, T. Ling, C. Lockhart, X.L. Li, T.K. Lewellen, Calibration Procedure for a Continuous Miniature Crystal Element (cMiCE) Detector, Ieee T Nucl Sci 57. 1023-1028. 2010. link .

D. DeWitt, N.G. Johnson-Williams, R.S. Miyaoka, X.L. Li, C. Lockhart, T.K. Lewellen, S. Hauck, Design of an FPGA-Based Algorithm for Real-Time Solutions of Statistics-Based Positioning, Ieee T Nucl Sci 57. 71-77. 2010. link .

A. Le Pogam, ALESSIO A, KANDEL B, KIROV A, BARRETT O, FERNANDEZ P, CHEZE-LE REST Catherine, VISVIKIS Dimitris, Comparison of PET reconstruction resolution recovery and post-reconstruction deconvolution for partial volume effect correction (PVC) in PET, Journal of nuclear medicine (JNM) 51. 557. 2010. link .

T.K. Lewellen, R.S. Miyaoka, L.R. MacDonald, D. DeWitt, M. Haselman, S. Hauck, Evolution of the design of a second generation FireWire based data acquisition system, Nuclear Science Symposium Conference Record (NSS/MIC), 2010 IEEE 2510-2514. 2010. link .

T.K. Lewellen, The challenge of detector designs for PET, AJR Am J Roentgenol 195. 301-309. 2010. link .

J.B. Bassingthwaighte, G.M. Raymond, E. Butterworth, A. Alessio, J.H. Caldwell, Multiscale modeling of metabolism, flows, and exchanges in heterogeneous organs, Ann N Y Acad Sci 1188. 111-120. 2010. link .

T. Xia, A.M. Alessio, P.E. Kinahan, Noise and Bias Properties of Monoenergetic Images from DECT used for Attenuation Correction with PET/CT and SPECT/CT, Proc Soc Photo Opt Instrum Eng 7622. 762225-762228. 2010. link .

A.M. Alessio, G.S. Phillips, A pediatric CT dose and risk estimator, Pediatr Radiol 40. 1816-1821. 2010. link .

M.J. Gelfand, S.E. Sharp, S.T. Treves, F.H. Fahey, M.T. Parisi, A.M. Alessio, Estimated cumulative radiation dose from PET/CT in children with malignancies, Pediatr Radiol 40. 1712-3; author reply 1714-5. 2010. link .

2009

A.M. Alessio, P.E. Kinahan, V. Manchanda, V. Ghioni, L. Aldape, M.T. Parisi, Weight-Based, Low-Dose Pediatric Whole-Body PET/CT Protocols, JOURNAL OF NUCLEAR MEDICINE 50. 1570-1578. 2009. link .

K.M. Champley, T.K. Lewellen, L.R. MacDonald, R.S. Miyaoka, P.E. Kinahan, Statistical LOR estimation for a high-resolution dMiCE PET detector, PHYSICS IN MEDICINE AND BIOLOGY 54. 6369-6382. 2009. link .

P.E. Kinahan, R.K. Doot, M. Wanner-Roybal, L.M. Bidaut, S.G. Armato, C.R. Meyer, G. McLennan, PET/CT Assessment of Response to Therapy: Tumor Change Measurement, Truth Data, and Error, TRANSLATIONAL ONCOLOGY 2. 223-230. 2009. link .

K. Lee, R.S. Miyaoka, T.K. Lewellen, A.M. Alessio, P.E. Kinahan, Impact on Image Noise of Incorporating Detector Blurring Into Image Reconstruction for a Small Animal PET Scanner, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 56. 2769-2776. 2009. link .

C. Liu, L.A. Pierce, A.M. Alessio, P.E. Kinahan, The impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging, PHYSICS IN MEDICINE AND BIOLOGY 54. 7345-7362. 2009. link .

C.R. Meyer, S.G. Armato, C.P. Fenimore, G. McLennan, L.M. Bidaut, D.P. Barboriak, M.A. Gavrielides, E.F. Jackson, M.F. McNitt-Gray, P.E. Kinahan, N. Petrick, B.S. Zhao, Quantitative Imaging to Assess Tumor Response to Therapy: Common Themes of Measurement, Truth Data, and Error Sources, TRANSLATIONAL ONCOLOGY 2. 198-210. 2009. link .

L. MacDonald, J. Edwards, T. Lewellen, D. Haseley, J. Rogers, P. Kinahan, Clinical Imaging Characteristics of the Positron Emission Mammography Camera: PEM Flex Solo II, JOURNAL OF NUCLEAR MEDICINE 50. 1666-1675. 2009. link .

J. Noh, J.A. Fessler, P.E. Kinahan, Statistical Sinogram Restoration in Dual-Energy CT for PET Attenuation Correction, IEEE TRANSACTIONS ON MEDICAL IMAGING 28. 1688-1702. 2009. link .

M. Haselman, S. Hauck, T.K. Lewellen, R.S. Miyaoka, FPGA-based pulse parameter discovery for positron emission tomography, Nuclear Science Symposium Conference Record (NSS/MIC), 2009 IEEE 2956-2961. 2009. link .

M. Haselman, N. Johnson-Williams, C. Jerde, M. Kim, S. Hauck, T.K. Lewellen, R. Miyaoka, FPGA vs. MPPA for Positron Emission Tomography pulse processing, Field-Programmable Technology, 2009. FPT 2009. International Conference on 231-238. 2009. link .

C. Liu, L.A.n. Pierce, A.M. Alessio, P.E. Kinahan, The impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging, Phys Med Biol 54. 7345-7362. 2009. link .

E. Lin, A. Alessio, What are the basic concepts of temporal, contrast, and spatial resolution in cardiac CT?, J Cardiovasc Comput Tomogr 3. 403-408. 2009. link .

2008

A.M. Alessio, R.E. Schmitz, L.R. MacDonald, S.D. Wollenweber, C.W. Stearns, S.G. Ross, A. Ganin, T.K. Lewellen, P.E. Kinahan, Image reconstruction for a partially collimated whole body PET scanner, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 55. 975-983. 2008. link .

F. Liu, C. Cuevas, A.A. Moss, O. Kolokythas, T.J. Dubinsky, P.E. Kinahan, Gas bubble motion artifact in MDCT, AMERICAN JOURNAL OF ROENTGENOLOGY 190. 294-299. 2008. link .

K. Champley, M. Defrise, R. Clackdoyle, R.R. Raylman, P.E. Kinahan, Planogram rebinning with the frequency-distance relationship, IEEE TRANSACTIONS ON MEDICAL IMAGING 27. 925-933. 2008. link .

R.R. Raylman, S. Majewski, M.F. Smith, J. Proffitt, W. Hammond, A. Srinivasan, J. McKisson, V. Popov, A. Weisenberger, C.O. Judy, B. Kross, S. Ramasubramanian, L.E. Banta, P.E. Kinahan, K. Champley, The positron emission mammography/tomography breast imaging and biopsy system (PEM/PET): design, construction and phantom-based measurements, PHYSICS IN MEDICINE AND BIOLOGY 53. 637-653. 2008. link .

R.R. Raylman, M.F. Smith, P.E. Kinahan, S. Majewski, Quantification of radiotracer uptake with a dedicated breast PET imaging system, MEDICAL PHYSICS 35. 4989-4997. 2008. link .

D. DeWitt, R. Miyaoka, S., Xiaoli, Li, C. Lockhart, T. Lewellen, K., S. Hauck, Design of an FPGA based algorithm for real-time solutions of Statistics-Based Positioning, Nuclear Science Symposium Conference Record, 2008. NSS '08. IEEE 5029-5035. 2008. link .
L. MacDonald, J. Edwards, T. Lewellen, J. Rogers, P. Kinahan, Clinical imaging characteristics of the positron emission mammography PEM Flex Solo II, Nuclear Science

R. Harrison, S. Gillispie, R. Schmitz, T. Lewellen, Modeling block detectors in SimSET, J Nucl Med 49 Suppl 1. 410P. 2008. link .

X. Li, C. Lockhart, T.K. Lewellen, R.S. Miyaoka, A high resolution, monolithic crystal, PET/MRI detector with DOI positioning capability, Conf Proc IEEE Eng Med Biol Soc 2008. 2287-2290. 2008. link .

L.R. Macdonald, R.E. Schmitz, A.M. Alessio, S.D. Wollenweber, C.W. Stearns, A. Ganin, R.L. Harrison, T.K. Lewellen, P.E. Kinahan, Measured count-rate performance of the Discovery STE PET/CT scanner in 2D, 3D and partial collimation acquisition modes, Phys Med Biol 53. 3723-3738. 2008. link .

X. Jiang, H. Kenerson, L. Aicher, R. Miyaoka, J. Eary, J. Bissler, R.S. Yeung, The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake, Am J Pathol 172. 1748-1756. 2008. link .

A.M. Alessio, P.E. Kinahan, APPLICATION OF A SPATIALLY VARIANT SYSTEM MODEL FOR 3-D WHOLE-BODY PET IMAGE RECONSTRUCTION, Proc IEEE Int Symp Biomed Imaging 2008. 1315-1318. 2008. link .

T.K. Lewellen, R.S. Miyaoka, L.R. Macdonald, M. Haselman, D. Dewitt, W. Hunter, S. Hauck, Design of a Second Generation Firewire Based Data Acquisition System for Small Animal PET Scanners, IEEE Nucl Sci Symp Conf Rec (1997) 2008. 5023-5028. 2008. link .

R.S. Miyaoka, S.K. Joo, K. Lee, Detector Light Response Modeling for a Thick Continuous Slab Detector, J Nucl Sci Technol 45. 634-638. 2008. link .

T.K. Lewellen, Recent developments in PET detector technology, Phys Med Biol 53. R287-317. 2008. link .

T. Ling, T.H. Burnett, T.K. Lewellen, R.S. Miyaoka, Parametric positioning of a continuous crystal PET detector with depth of interaction decoding, Phys Med Biol 53. 1843-1863. 2008. link .

2007

A. Alessio, K. Sauer, P. Kinahan, Statistical image reconstruction from correlated data with applications to PET, PHYSICS IN MEDICINE AND BIOLOGY 52. 6133-6150. 2007. link .

A.M. Alessio, S. Kohmyer, K. Branch, G. Chen, J. Caldwell, P. Kinahan, Cine CT for attenuation correction in cardiac PET/CT, JOURNAL OF NUCLEAR MEDICINE 48. 794-801. 2007. link .

G.P. Chen, K.R. Branch, A.M. Alessio, P. Pham, R. Tabibiazar, P. Kinahan, J.H. Caldwell, Effect of reconstruction algorithms on myocardial blood flow measurement with N-13-ammonia PET, JOURNAL OF NUCLEAR MEDICINE 48. 1259-1265. 2007. link .

R.K. Doot, L.K. Dunnwald, E.K. Schubert, M. Muzi, L.M. Peterson, P.E. Kinahan, B.F. Kurland, D.A. Mankoff, Dynamic and static approaches to quantifying F-18-FDG uptake for measuring cancer response to therapy, including the effect of granulocyte CSF, JOURNAL OF NUCLEAR MEDICINE 48. 920-925. 2007. link .

H.C. Gifford, P.E. Kinahan, C. Lartizien, M.A. King, Evaluation of multiclass model observers in PET LROC studies, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 54. 116-123. 2007. link .

T. Ling, T.K. Lewellen, R.S. Miyaoka, Depth of interaction decoding of a continuous crystal detector module, Phys Med Biol 52. 2213-2228. 2007. link .

R.S. Miyaoka, L. Tao, T.K. Lewellen, Effect of Number of Readout Channels on the Intrinsic Spatial Resolution Performance of a Continuous Miniature Crystal Element (cMiCE) Detector, Nuclear Science, IEEE Transactions on 54. 1561-1567. 2007. link .

R.E. Schmitz, R.L. Harrison, C.W. Stearns, T.K. Lewellen, P.E. Kinahan, Optimization of Noise Equivalent Count Rate Performance for a Partially Collimated PET Scanner by Varying the Number of Septa, Medical Imaging, IEEE Transactions on 26. 935-944. 2007. link

R.E. Schmitz, R.L. Harrison, C.W. Stearns, T.K. Lewellen, P.E. Kinahan, Optimization of noise equivalent count rate performance for a partially collimated PET scanner by varying the number of septa, IEEE Trans Med Imaging 26. 935-944. 2007. link

R.S. Miyaoka, T. Ling, T.K. Lewellen, Effect of Number of Readout Channels on the Intrinsic Spatial Resolution Performance of a Continuous Miniature Crystal Element (cMiCE) Detector, IEEE Trans Nucl Sci 54. 1561-1567. 2007. link

2006

A. Alessio, K. Sauer, P. Kinahan, Analytical reconstruction of deconvolved Fourier rebinned PET sinograms, PHYSICS IN MEDICINE AND BIOLOGY 51. 77-93. 2006. link

A.M. Alessio, P.E. Kinahan, Improved quantitation for PET/CT image reconstruction with system modeling and anatomical priors, MEDICAL PHYSICS 33. 4095-4103. 2006. link

A.M. Alessio, P.E. Kinahan, T.K. Lewellen, Modeling and incorporation of system response functions in 3-D whole body PET, IEEE TRANSACTIONS ON MEDICAL IMAGING 25. 828-837. 2006. link

E.C. Ford, P.E. Kinahan, L. Hanlon, A. Alessio, J. Rajendran, D.L. Schwartz, M. Phillips, Tumor delineation using PET in head and neck cancers: Threshold contouring and lesion volumes, MEDICAL PHYSICS 33. 4280-4288. 2006. link

L.X. Gong, S. Pathak, A. Alessio, P. Kinahan, Automatic arm removal in PET and CT images for deformable registration, COMPUTERIZED MEDICAL IMAGING AND GRAPHICS 30. 469-477. 2006. link

L. Janeiro, C. Comtat, C. Lartizien, P.E. Kinahan, C. Michel, R. Trebossen, P. Almeida, Numerical observer studies comparing FORE plus AWOSEM, FORE plus NECOSEM, and NEC based fully 3-D OSEM for 3-D whole-body PET imaging, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 53. 1194-1199. 2006. link

P.E. Kinahan, A.M. Alessio, J.A. Fessler, Dual energy CT attenuation correction methods for quantitative assessment of response to cancer therapy with PET/CT imaging, TECHNOLOGY IN CANCER RESEARCH & TREATMENT 5. 319-327. 2006. link

G.N. Mann, J.M. Link, P. Pham, C.A. Pickett, D.R. Byrd, P.E. Kinahan, K.A. Krohn, D.A. Mankoff, [C-11]Metahydroxyephedrine and [F-18]fluorodeoxyglucose positron emission tomography improve clinical decision making in suspected pheochromocytoma, ANNALS OF SURGICAL ONCOLOGY 13. 187-197. 2006. link

M.R. Tanas, M.L. Comstock, R.S. Miyaoka, J. Woodell, B.P. Rubin, A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E: Utility as a pre-clinical model, Modern Pathol 19. 294A-294A. 2006. link

T. Ling, K. Lee, R.S. Miyaoka, Performance comparisons of continuous miniature crystal element (cMiCE) detectors, Ieee T Nucl Sci 53. 2513-2518. 2006. link

R.E. Schmitz, P.E. Kinahan, R.L. Harrison, T.K. Lewellen, Simulations of the Effect of Collimation on Count Rates of an LSO PET System, IEEE Nucl Sci Symp Conf Rec (1997) 5. 3049-3052. 2006. link

L.R. Macdonald, R.E. Schmitz, A.M. Alessio, S.D. Wollenweber, C.W. Stearns, A. Ganin, R.L. Harrison, T.K. Lewellen, P.E. Kinahan, Count-Rate Performance of the Discovery STE PET Scanner Using Partial Collimation, IEEE Nucl Sci Symp Conf Rec (1997) 4. 2488-2493. 2006. link

P. Kinahan, H. Vesselle, J. Williams, C. Stearns, R. Schmitz, A. Alessio, L.M. Macdonald, Osama, T. Turkington, T. Lewellen, Performance evaluation of an integrated PET/CT scanner: Discovery STE, J NUCL MED 47. 392P-a. 2006. link

P. Kinahan, H. Vesselle, L. Macdonald, A. Alessio, S. Kohlmyer, T. Lewellen, Whole-body respiratory gated PET/CT, J NUCL MED 47. 187P-a-. 2006. link

B. Lewellen, D. Cross, S. Craft, L. Baker, T. Kosugi, H. Okada, T. Lewellen, P. Kinahan, S. Minoshima, Improved PET Detection of Focal Brain Activity Using Subset-dependent Relaxation `Dynamic' Row-action Maximum Likelihood Algorithm (DRAMA), Nuclear Science Symposium Conference Record, 2006. IEEE 4. 2177-2179. 2006. link



For a complete list of all publications feel free to reach out to any member of the team.

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