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Wangerin KA, Ahn S, Wollenweber S, Ross SG, Kinahan PE, et al.  Evaluation of Lesion Detectability in Positron Emission Tomography When Using a Convergent Penalized Likelihood Image Reconstruction Method, J. Med. Imag. 4(1), 011002 (Nov 22, 2016).

Rosen M, Kinahan PE, Gimpel J, Opanowski A, Hill GC, Weiss L, Shankar L. Performance Observations of Scanner Qualification of NCI-designated Cancer Centers: Results from the Centers of Quantitative Imaging Excellence (CQIE) Program. Academic Radiology. vol.24(2):232–245, 2017.

McNew LK, Bowen SR, Gopan O, Nyflot MJ, Patel SA, Zeng J, Rengan R. The Relationship Between Cardiac Radiation Dose and Mediastinal Lymph Node Involvement in Stage III Non-Small Cell Lung Cancer Patients Adv Radiat Oncol.


Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O'Sullivan F, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Layman CM, Muzi M, Kinahan PE, Schmainda K, Cao Y, Chenevert T, Taoluli B, Yankeelov TE, Fennessy FM, Li X. The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge. Tomography 2:56-66, 2016. PMID: 27200418. PMCID: PMC4869732

Gong K, Majewski S, Kinahan PE, Harrison RL, Elston BF, Manjeshwar R, Dolinsky S, Stolin AV, Brefczynski-Lewis JA, Qi J. Designing a Compact High Performance Brain PET Scanner-Simulation Study. Phys Med Biol 61(10):3681-3697, 2016. PMID: 27081753. PMCID: PMC4863179. Note: This was the most downloaded research paper from Physics in Medicine and Biology in 2016.

Chen KY, Cypess AM, Laughlin MR, Haft CR, Hu HH, Bredella MA, Enerbäck S, Kinahan PE, Lichtenbelt W, Lin FI, Sunderland JJ, Virtanen KA, Wahl RL. Brown Adipose Reporting Criteria in Imaging Studies (BARCIST 1.0): Recommendations for Standardized FDG-PET/CT Experiments in Humans. Cell Metab 24(2):210-222, 2016. PMID: 27508870. PMCID: PMC4981083.

Hatt M, Tixier F, Pierce L, Kinahan PE, Le Rest CC, Visvikis D. Characterization of PET/CT Images Using Texture Analysis: The Past, the Present… Any Future? Eur J Nucl Med Mol Imaging 44(1):151-165, 2017. PMID: 27271051. PMCID: ?

Byrd DW, Doot RK, Allberg KC, MacDonald LR, McDougald WA, Elston BF, Linden HM, Kinahan PE. Evaluation of Cross-calibrated 68Ge/68Ga Phantoms for Assessing PET/CT Measurement Bias in Oncology Imaging for Single Center and Multicenter Trials Tomography, Vol.2(4):353-360, 2016.

Rui X, Jin Y, FitzGerald PF, Wu M, Alessio AM, Kinahan PE, De Man B. Fast Analytical Approach of Application Specific Dose Efficient Spectrum Selection for Diagnostic CT Imaging and PET Attenuation Correction. Phys Med Biol 61(21):7787-7811, 2016. PMID: 27754977.

Morrocchi M, Hunter WC, Del Guerra A, Lewellen TK, Kinahan PE, MacDonald LR, Bisogni MG, Miyaoka RS. Evaluation of Event Position Reconstruction in Monolithic Crystals that are Optically Coupled. Phys Med Biol 61(23):8298-8320, 2016. PMID: 27811385. PMCID: PMC5132859.

Fu L, Lee TC, Kim SM, Alessio A, Kinahan P, Chang Z, Sauer K, Kalra M, De Man B. Comparison between Pre-log and Post-log Statistical Models in Ultra-Low-Dose CT Reconstruction. IEEE Trans Med Imaging 2016. PMID: 27845657.

Jorge LS, Bonifacio DAB, DeWitt D, Miyaoka RS Experimental Validation of Improved 3D SBP Positioning Algorithm in PET Applications using UW Phase II Board NIMA, vol. 838: p.103-108

Spraker MB, Nyflot MJ, Hendrickson KRG, Ford EC, Kane G, Zeng J. A Survey of Residents’ Experience with Patient Safety and Quality Improvement Concepts in Radiation Oncology Pract Radiat Oncol.

Novak A, Nyflot MJ, Sponseller P, Howard J, Logan W, Holland L, Jordan L, Carlson J, Ermoian RP, Kane G, Ford EC, Zeng J. Targeting Safety Improvements through Identification of Incident Origination and Detection in a Near-Miss Incident Learning System. Med Phys 43(5):2053, 2016. PMID: 27147317.

Meyer J, Nyflot MJ, Smith WP, Wooten LS, Young LA, Yang F, Kim M, Hendrickson KRG, Ford EC, Kalet A, Cao N, Dempsey CL, Sandison GA. Electron Beam Energy QA – A Note on Measurement Tolerances. J Appl Clin Med Phys 17(2):1, 2016. PMID: 27074488.

Mullen T, Nyflot MJ, Zeng J, Jordan L, Sponseller LA, Carlson JC, Kane G, Ford EC. Assessing the Inter-Rater Reliability of a Near-Miss Risk Index for Incident Learning Systems. Pract Radiat Oncol 6(6):429, 2016. PMID: 27209311.

Zeng J, Nyflot MJ, Jordan LE, Sponseller PA, Novak A, Carlson J, Ermoian RP, Kane GM, Ford EC. Best Practices for Safety Improvement through High-Volume Institutional Incident Learning: Lessons Learned from Two Years. J Radiat Oncol 5:323, 2016.

Cao N, Ford EC, Nyflot MJ, Ermoian RP, Pelly NW, Young LA, Hendrickson KRG. TBI Technique Improvements for Anesthetized Pediatric Patients based on Near-Miss Incident Reporting. IJMPCERO 5(4):270, 2016.

Gensheimer M, Nyflot MJ, Laramore GE, Liao JJ, Parvathaneni U. Contribution of Submandibular Gland and Swallowing Structure Sparing to Post-Radiation Therapy PEG Dependence in Oropharynx Cancer Patients Treated With Split-Neck IMRT Technique. Radiat Oncol 15;11(1):151, 2016. PMID: 27846899.

Gopan O, Zeng J, Novak A, Nyflot MJ, Ford EC. The Effectiveness of Pre-Treatment Physics Plan Review for Detecting Errors in Radiation Therapy. Med Phys 43(9):5181, 2016. PMID: 27587048.

Zeng YC, Vyas S, Dang Q, Schultz L, Bowen SR, Wong T, Shankaran V, Farjah F, Oleschlager BK, Apisarnthanarax S, Zeng J. Proton Therapy Posterior Beam Approach with Pencil Beam Scanning for Esophageal Cancer: Clinical Outcome, Dosimetry, and Feasibility Strahlenther Onkol (2016).

Saini J, Cao N, Bowen SR, Herrera M, Nicewonger D, Wong T, Bloch CD. Clinical Commissioning and Comprehensive Evaluation of a Commercially Available Pencil Beam Scanning Treatment Planning System for Proton Therapy at Seattle Proton Therapy Center Int J Particle Therapy (2016).

Chapman TR, Laramore GE, Bowen SR, Orio PF. Neutron Radiotherapy for Advanced Thyroid Cancers Adv Radiat Oncol (2016).

Elojeimy S, Cruite I, Zeng J, Vesselle HJ, Pulmonary Ventilation and Perfusion Imaging in the Era of SPECT-CT: Novel and Improved Applications Am J Roentgenol (2016).

Bowen SR, Borgman J, Chapman TR, Miyaoka RS, Kinahan PE, Sandison GA, Vesselle HJ, Nyflot MJ, Apisarnthanarax S. Measuring Total Liver Function on Sulfur Colloid SPECT/CT for Improved Risk Stratification and Outcome Prediction of Hepatocellular Carcinoma Patients. EJNMMI Res 6(57)1:10, 2016. PMID: 27349530. PMCID: PMC4923007.

MacDonald LR, Perkins AE, Tung CH, Longitudinal Monitoring of Reconstructed Activity Concentration on a Clinical Time-of-flight PET/CT Scanner, J. Med. Imag. 4(1), 011004 (2017), doi: 10.1117/1.JMI.4.1.011004.

Alessio AM, Farrell MB, Fahey FH, Role of Reference Levels in Nuclear Medicine: A Report of the SNMMI Dose Optimization Task Force, Journal of Nuclear Medicine, vol 56:12, pp 1960-1964, 2015.

Bindschadler M, Modgil D, Branch KR, La Riviere P, Alessio AM, Comparison of Static and Dynamic Perfusion Cardiac CT for Quantitation and Patient Classification Tasks, Proc. SPIE 9412, Medical Imaging 2015: Physics of Medical Imaging, 941224 (March 18, 2015); doi:10.1117/12.2082098

Perlmutter D, Kim SM, Kinahan PE, Alessio AM, Mixed Confidence Estimation for Iterative CT Reconstruction, IEEE Trans on Medical Imaging, vol. 35:9, pp 2005-2014, 2016.

Wollenweber SD, Alessio AM, Kinahan PE, A Phantom Design for Assessment of Detectability in PET Imaging, Medical Physics, vol 43:9, 2016.

McDougald WM, Miyaoka RS, Alessio AM, Harrison RL, and Lewellen TK, A Study of SPECT/CT Camera Stability for Quantitative Imaging, EJNMMI Phys, vol 3:1, 2016. PMCID: PMC4967048.

Lehnert AL, Hunter WCJ, Lewellen TK, Miyaoka R, Depth of Interaction Calibration and Capabilities in 2x2 Discrete Crystal Arrays and Digital Silicon Photomultipliers. IEEE TNS v63(1):4-7, 2016.

Lee TC, Alessio AM, Miyaoka RM, Kinahan PE. Morphology supporting function: attenuation correction for SPECT/CT, PET/CT, and PET/MR imaging. Q J Nucl Med Mol Imaging 60:25-39, 2016. PMID: 26576737.

MacDonald LR, Hippe DS, Bender LC, Cotter EW, Voria PR, Hallam PS, Wang CL, Haseley DR, Kelly MM, Parikh JR, Beatty JD, Rogers JV Positron Emission Mammography Image Interpretation for Reduced Image Count Levels J Nucl Med vol. 57 no. 3 348-354 PMID:26635337 [PubMed - in process]

Gilles RJ, Kinahan PE, Hricak H. Radiomics: Images are more than pictures, they are data. Radiology vo.278(2):563-577, 2016. PMID: 26579733 PMCID:PMC4734157 [Available on 2017-02-01]

Yankeelov TE, Mankoff DA, Schwartz LH, Lieberman FS, Buatti JM, Mountz JM, Erickson BJ, Fennessy FMM, Huanf W, Kalpathy-Cramer J, Wahl RL, Linden HM, Kinahan PE, Zhao B, Hylton NM, Gillies RJ, Clarke L, Nofrdstrom R, Rubin DL. Quantitative Imaging in Cancer Clinical Trials. Clinical Cancer Research 22:284-290, 2016. PMID:26773162PMCID:PMC4717912 [Available on 2017-01-15]

Nancy A. Obuchowski NA, Buckler A, Kinahan PE, Chen-Mayer H, Petrick N, Bullen J, Sullivan DC. Statistical Issues in Testing Conformance with the Quantitative Imaging Biomarker Alliance (QIBA) Profile Claims. Academic Radiology (Accepted) 2016.

Kurland BF, Muzi M, Peterson, LM, Doot RK, Wangerin KA, Mankoff DA, Linden HM, Kinahan PE Multicenter clinical trials using 18F-FDG PET to measure early oncology therapy response: Effects of injection-to-acquisition time variability on required sample size. J Nucl Med (Accepted), 2016.

Pierce LA II, Byrd DW, Elston BF, Karp JS, Sunderland JJ, Kinahan PE. An algorithm for automated ROI definition in water or epoxy-filled NEMA NU-2 image quality phantoms. Journal of Applied Clinical Medical Physics vol 17(1):440-456, 2016.


Ciarrocchi E, Belcaria N, 
 Del Guerraa A, 
Cherry SR, Lehnert A, Hunter WJ, 
 McDougald WA, Miyaoka RS,
Kinahan PE. Cherenkov luminescence measurements with digital silicon photomultipliers: a feasibility study. European Journal of Nuclear Medicine and Molecular Imaging B: Physics 2(32):1-22, 2015

Wangerin KA, Muzi M, Peterson LM, Linden HM, Novakova A, O’Sullivan F, Kurland BF, Mankoff DA, Kinahan PE.  Effect of 18F-FDG uptake time on lesion detectability in PET imaging of early stage breast cancerTomography 1(1) (2015) 53-60. PMCID: PMC4721230.

Hawkins-Daarud A, Rockne R, Corwin D, Anderson AR, Kinahan P, Swanson KR. In silico analysis suggests differential response to bevacizumab and radiation combination therapy in newly diagnosed glioblastoma. J R Soc Interface 12:20150388, 2015. PMID: 26202682.PMCID: PMC4535409.

Nyflot MJ, Kruser TJ, Traynor AM, Khuntia D, Yang DT, Hartig GK, McCulloch TM, Wiederholt PA, Gentry LR, Hoang T, Jeraj R, and Harari PM. Phase I trial of bevacizumab with concurrent chemoradiotherapy for squamous cell carcinoma of the head and neck with exploratory functional imaging of tumor hypoxia, proliferation and perfusion. Int J Radiat Oncol Biol Phys 2015, 91(5):942-951.

Kinahan PE, Mankoff DA, Linden HM. The Value of Establishing the Quantitative Accuracy of PET/CT Imaging. J Nucl Med 56:1133-1134, 2015. PMID: 26089552.

Rui X, Cheng L, Long Y, Fu L, Alessio AM, Asma E, Kinahan PE, De Man B. Ultra-low dose CT attenuation correction for PET/CT: analysis of sparse view data acquisition and reconstruction algorithms. Phys Med Biol 60:7437-7460, 2015. PMID: 26352168.

Nyflot MJ, Yang F, Byrd D, Bowen SR, Sandison GA, Kinahan PE. Quantitative radiomics: impact of stochastic effects on textural feature analysis implies the need for standards. J Med Imaging (Bellingham) 2:041002, 2015. PMID: 26251842.PMCID: PMC4524811.

Nyflot MJ, Lee TC, Alessio AM, Wollenweber SD, Stearns CW, Bowen SR, Kinahan PE. Impact of CT attenuation correction method on quantitative respiratory-correlated (4D) PET/CT imaging. Med Phys 42:110-120, 2015. PMID: 25563252.

Bowen SR, Nyflot MJ, Herrmann C, Groh CM, Meyer J, Wollenweber SD, Stearns CW, Kinahan PE, Sandison GA. Imaging and dosimetric errors in 4D PET/CT-guided radiotherapy from patient-specific respiratory patterns: a dynamic motion phantom end-to-end study. Phys Med Biol 60:3731-3746, 2015. PMID: 25884892.PMCID: PMC4425357.

Chapman TR, Kumarapeli AR, Nyflot MJ, Bowen SR, Yeung R, Vesselle H, Yeh MM, Apisarnthanarax S. Functional imaging of radiation induced liver injury: imaging and pathologic correlation. J Gastrointest Oncol 2015, 6(3):E44-47.

Bowen SR, Saini J, Chapman TR, Miyaoka RS, Kinahan PE, Sandison GA, Wong T, Vesselle HJ, Nyflot MJ, Apisarnthanarax S. Differential hepatic avoidance radiation therapy: Proof of concept in hepatocellular carcinoma patients. Radiother Oncol 115:203-210, 2015. PMID: 25934165.

Bradshaw T, Fu R, Bowen SR, Zhu J, Forrest L, Jeraj R. Predicting location of recurrence using FDG, FLT, and Cu-ATSM PET in canine sinonasal tumors treated with radiotherapy. Phys Med Biol. 2015 Jul 7;60(13):5211-24. doi: 10.1088/0031-9155/60/13/5211. Epub 2015 Jun 17. PubMed PMID: 26083082.

Liu, Kerwin, Caldwell, Ferguson, Hippe, Alessio, Martinez-Malo, Pimentel, Miyaoka, Kohler, Hatsukami, Yuan, High Resolution FDG-MicroPET of Carotid Atherosclerosis: Plaque Components Underlying Enhanced FDG Uptake. International Journal of Cardiovascular Imaging, 2015.

Swanson, Alessio, White, Krengel, Friedman, Vining, Song, Spine CT Radiation Dose Reduction: Protocol Refinement Based On Measurement Variation At Simulated Lower Radiation Acquisitions. Spine. Publish Ahead of Print, 2015.

Pierce LA, Elston BF, Clunie DA, Nelson D, Kinahan PE. A Digital Reference Object to Analyze Calculation Accuracy of PET Standardized Uptake Value. Radiology 141262, 2015. PMID: 25989387.

Lodge MA, Holt DP, Kinahan PE, Wong DF, Wahl RL. Performance assessment of a NaI(Tl) gamma counter for PET applications with methods for improved quantitative accuracy and greater standardization. EJNMMI Phys 2 2015. PMID: 26046011.PMCID: PMC4452125.

Williams JM, Rani SD, Li X, Arlinghaus LR, Lee TC, MacDonald LR, Partridge SC, Kang H, Whisenant JG, Abramson RG, Linden HM, Kinahan PE, Yankeelov TE. Comparison of prone versus supine 18F-FDG-PET of locally advanced breast cancer: Phantom and preliminary clinical studies. Med Phys 42:3801-3813, 2015. PMID: 26133582.PMCID: PMC4464063.

Vaquero JJ, Kinahan PE. Positron Emission Tomography: Current Challenges and Opportunities for Technology Advances in Clinical and Pre-Clinical Imaging Systems. Annual Review of Biomedical Engineering, Vol. 17 (in press) 2015.

Graham MM, Wahl RL, Hoffman JM, Yap JT, Sunderland JJ, Boellaard R, Perlman ES, Kinahan PE, Christian PE, Hoekstra OS, Dorfman GS. Summary of the UPICT Protocol for 18F-FDG PET/CT Imaging in Oncology Clinical Trials. J Nucl Med 56:955-961, 2015. PMID: 25883122.

Huang EP, Wang XF, Choudhury KR, McShane LM, Gönen M, Ye J, Buckler AJ, Kinahan PE, Reeves AP, Jackson EF, Guimaraes AR, Zahlmann G, Meta-Analysis WG. Meta-analysis of the technical performance of an imaging procedure: guidelines and statistical methodology. Stat Methods Med Res 24:141-174, 2015. PMID: 24872353.

Obuchowski NA, Reeves AP, Huang EP, Wang X-F, Buckler AJ, Kim HJG, Barnhart HX, Jackson EF, Giger ML, Pennello G, Toledano AY, Kalpathy-Cramer J, Apanasovich TV, Kinahan PE, Myers KJ, Goldgof DB, Barboriak DP, Gillies RJ, Schwartz LH, Sullivan DC, for TACWG. Quantitative imaging biomarkers: A review of statistical methods for computer algorithm comparisons. Statistical Methods in Medical Research 24:68-106, 2015.


He J, Yu Y, Prasad B, Link J, Miyaoka RS, Chen, X, and Unadkat, JD Unadkat. PET Imaging of Oatp-Mediated Hepatobiliary Transport of [11C] Rosuvastatin in the Rat. Molecular Pharmaceutics 2014 11 (8), 2745-2754 DOI: 10.1021/mp500027c

Rockne RC, Trister AD, Jacobs J, Hawkins-Daarud AJ, Neal ML, Hendrickson K, Mrugala MM, Rockhill JK, Kinahan P, Krohn KA, Swanson KR. A patient-specific computational model of hypoxia-modulated radiation resistance in glioblastoma using 18F-FMISO-PET. J R Soc Interface 12 2015. PMID: 25540239.PMCID: PMC4305419.

Chen D, Kinahan P. Multimodality molecular imaging of the lung. Clin Transl Imaging Clinical and Translational Imaging 2:391-401, 2014.

Bradshaw T. J., Bowen S. R., Deveau M., Kubicek L., White P., Bentzen S. M., Chappell R. J., Forrest L., Jeraj R., Molecular imaging biomarkers of resistance to radiation therapy in canines with spontaneous nasal tumors. Int J Rad Oncol Biol Phys (in press) (2014).

Nyflot MJ, Cao N, Meyer J, Ford EC. Improved accuracy for noncoplanar radiotherapy: an EPID-based method for sub-millimeter alignment of accelerator table rotation about MV isocenter. J Appl Clin Med Phys 2014, 15(2):1.

Toney, Wanner, Miyaoka, Alessio, Wood, Vesselle. Improved Prediction of Lobar Perfusion Contribution Using Tc-99m MAA SPECT/CT with Attenuation Correction. Journal of Thoracic and Cardiovascular Surgery, vol 148:5, pp 2345-52, 2014.

Nesterov, Deshayes, Sciagrà, Settimo, Declerck, Pan, Yoshinaga, Katoh, Slomka, Germano, Han, Aalto, Alessio, Ficaro, Lee, Nekolla, Gwet, deKemp, Klein, Dickson, Case, Bateman, Prior, Knuuti, Quantification of Myocardial Blood Flow in Absolute Terms Using 82Rb PET Imaging: Results of RUBY-10 Study. JACC: Cardiovascular Imaging, vol 7:11, pp 1119-27, 2014.

Modgil, Alessio, Bindschadler, and La Rivière, Sinogram smoothing techniques for myocardial blood flow estimation from dose-reduced dynamic CT. Journal of Medical Imaging (SPIE), vol 1:3, 2014.

Tashima H, Yamaya T, Kinahan PE. An OpenPET scanner with bridged detectors to compensate for incomplete data. Phys Med Biol 59:6175-6193, 2014. PMID: 25255296.

Bowen SR, Pierce LA, Alessio AM, Liu C, Wollenweber SD, Stearns CW, Kinahan PE. Assessment of patient selection criteria for quantitative imaging with respiratory-gated positron emission tomography. J Med Imaging (Bellingham) 1:026001, 2014. PMID: 26158039.PMCID: PMC4478885.

Pierce LA, Hunter WC, Haynor DR, MacDonald LR, Kinahan PE, Miyaoka RS. Multiplexing strategies for monolithic crystal PET detector modules. Phys Med Biol 59:5347-5360, 2014. PMID: 25146849.PMCID: PMC4157903.

Phillips GS, Stanescu AL, Alessio AM. Relationships of Pediatric Anthropometrics for CT Protocol Selection. American Journal of Roentgenology. 2014;203: W85-W91.

Mountz JM, Yankeelov TE, Rubin DL, Buatti JM, Erikson BJ, Fennessy FM, Gillies RJ, Huang W, Jacobs MA, Kinahan PE, Laymon CM, Linden HM, Mankoff DA, Schwartz LH, Shim H, Wahl RL. Letter to cancer center directors: Progress in quantitative imaging as a means to predict and/or measure tumor response in cancer therapy trials. J Clin Oncol 32:2115-2116, 2014. PMID: 24868025.

Bindschadler, Modgil, Branch, La Riviere, Alessio, Comparison of Blood Flow Models and Acquisitions for Quantitative Myocardial Perfusion Estimation from Dynamic CT Physics in Medicine and Biology, vol 59:7, 2014.

Doot RK, Pierce LA, Byrd D, Elston B, Allberg KC, Kinahan PE. Biases in Multicenter Longitudinal PET Standardized Uptake Value Measurements. Transl Oncol 7:48-54, 2014. PMID: 24772207.PMCID: PMC3998681.

Harrison RL, Elston BF, Doot RK, Lewellen TK, Mankoff DA, Kinahan PE. A Virtual Clinical Trial of FDG-PET Imaging of Breast Cancer: Effect of Variability on Response Assessment. Transl Oncol 7:138-146, 2014. PMID: 24772217.PMCID: PMC3998682.

Chenevert TL, Malyarenko DI, Newitt D, Li X, Jayatilake M, Tudorica A, Fedorov A, Kikinis R, Liu TT, Muzi M, Oborski MJ, Laymon CM, Li X, Thomas Y, Jayashree KC, Mountz JM, Kinahan PE, Rubin DL, Fennessy F, Huang W, Hylton N, Ross BD. Errors in Quantitative Image Analysis due to Platform-Dependent Image Scaling. Transl Oncol 7:65-71, 2014. PMID: 24772209.PMCID: PMC3998685.

Kalpathy-Cramer J, Freymann JB, Kirby JS, Kinahan PE, Prior FW. Quantitative Imaging Network: Data Sharing and Competitive AlgorithmValidation Leveraging The Cancer Imaging Archive. Transl Oncol 7:147-152, 2014. PMID: 24772218.PMCID: PMC3998686.

Huang W, Li X, Chen Y, Li X, Chang MC, Oborski MJ, Malyarenko DI, Muzi M, Jajamovich GH, Fedorov A, Tudorica A, Gupta SN, Laymon CM, Marro KI, Dyvorne HA, Miller JV, Barbodiak DP, Chenevert TL, Yankeelov TE, Mountz JM, Kinahan PE, Kikinis R, Taouli B, Fennessy F, Kalpathy-Cramer J. Variations of dynamic contrast-enhanced magnetic resonance imaging in evaluation of breast cancer therapy response: a multicenter data analysis challenge. Transl Oncol 7:153-166, 2014. PMID: 24772219.PMCID: PMC3998693.

Lewellen, T.K., DeWitt, D., Miyaoka, R.S., Hauck, S.: A Building Block for Nuclear Medicine Imaging Systems Data Acqusition. IEEE Tran Nuc Sci 61, pp. 79-87 (2014). PMID PMC3833631

Xia T, Alessio AM, Kinahan PE. Dual energy CT for attenuation correction with PET/CT. Med Phys 41:012501, 2014. PMID: 24387525.PMCID: PMC3869851.

Wang S, Bowen SR, Chaovalitwongse WA, Sandison GA, Grabowski TJ, Kinahan PE. Respiratory trace feature analysis for the prediction of respiratory-gated PET quantification. Phys Med Biol 59:1027-1045, 2014. PMID: 24504153.PMCID: PMC4000406.


T. J. Bradshaw, S. R. Bowen, N. Jallow, L. Forrest, and R. Jeraj, “Intratumor correlations of FDG, FLT, and Cu-ATSM PET in canine sarcoma and carcinoma tumors: implications for dose painting,” J Nucl Med (in press) (2013).

R Jeraj, SR Bowen, N Jallow, MJ Nyflot, M Vanderhoek. Molecular Imaging in Radiation Oncology. In J Van Dyk Modern Technologies of Radiation Therapy, Volume 3. 2013.

W.P. Shuman , D.E. Green, J.M. Busey, O Kolokythas, L.M. Mitsumori, K.M. Koprowicz, J-B Thibault, J. Hsieh, A.M. Alessio, P.E. Kinahan, Model Based Iterative Reconstruction (MBIR) versus Adaptive Statistical Iterative Reconstruction (ASIR) and Filtered Back Projection (FBP) in Low Radiation Dose 64 Channel Liver CT: Focal Lesion Detection, Lesion Conspicuity, and Image Noise. AJR, 200(5) 1071-1076, 2013. link

W.C.J.Hunter, H.H. Barrett, J.P. Muzi, W. McDougald, L.R. MacDonald, R.S. Miyaoka, T.K. Lewellen, SCOUT: a fast Monte-Carlo modeling tool of scintillation camera, Phys. Med. Biol., Vol 58, pp. 3581–3598, (2013), link.

X. Li, A.M. Alessio, T.H. Burnett, T.K. Lewellen, R.S. Miyaoka, Performance Evaluation of Small Animal PET Scanners With Different System Designs, Nuclear Science, IEEE Transactions on PP. 1-8. 2013. link .

S.M. Kraynik, R.S. Miyaoka, J.A. Beavo, PDE3 and PDE4 isozyme selective inhibitors are both required for synergistic activation of brown adipose tissue, Mol Pharmacol 2013. link .

A. Alessio, J. Bassingthwaighte, S. Glenny, J. Caldwell, Validation of an Axially-Distributed Model for Quantification of Myocardial Blood Flow using 13N-Ammonia PET Journal of Nuclear Cardiology, vol 20:1, pp 64-75, 2013.

A. Alessio and LR MacDonald, Quantitative Material Characterization from Multi-Energy Photon Counting CT, Med. Phys., vol 40:3, 2013.

SA. Padia, A. Alessio, Kwan, Lewis, Vaidya, Minoshima, "Comparison of PET and Bremsstrahlung imaging to detect particle distribution in patients undergoing Yttrium-90 radioembolization for large hepatocellular carcinomas or associated portal vein thrombosis" Journal of Vascular and Interventional Radiology, Vol 24:8, pp 1147-1153, 2013.

Khorsand, Song, Swanson, A. Alessio, Redding, Waldhausen, “Iatrogenic Radiation Exposure to Patients With Early Onset Spine and Chest Wall Deformitie" Spine, vol 38:17, pp 1108-14, 2013.

MacDonald LR, Hunter WCJ, Kinahan PE, Miyaoka RS, Effects of Detector Thickness on Geometric Sensitivity and Event Positioning Errors in the Rectangular PET/X Scanner. IEEE TNS v60(5):3242-3252, 2013 2013. link. PMID: 26160982 [PubMed] PMCID: PMC4494122 

Makris NE, Huisman MC, Kinahan PE, Lammertsma AA, Boellaard R. Evaluation of strategies towards harmonization of FDG PET/CT studies in multi-centre trials: comparison of scanner validation phantoms and data analysis procedures. Eur J Nucl Med Mol Imaging 2013 Oct;40(10):1507-15. doi: 10.1007/s00259-013-2465-0. Epub 2013 Jun 11. link.

Kurland BF, Doot RK, Linden HM, Mankoff DA, Kinahan PE. Multicenter trials using FDG PET to predict chemotherapy response: Effects of differential measurement error and bias on power calculations for unselected and enrichment designs. Clinical Trials, 2013.


S. R. Bowen, R. J. Chappell, S. M. Bentzen, M. A. Deveau, L. Forrest and R. Jeraj, “Spatially resolved multivariate regression of pre-treatment FDG, FLT, and Cu-ATSM PET from post-treatment FDG PET: an exploratory study,” Radiother Onc 105, 41-48 (2012).

MJ Nyflot, PM Harari, S Yip, SB Perlman, R Jeraj: Correlation of PET images of metabolism, proliferation and hypoxia to characterize tumor phenotype in patients with cancer of the oropharynx. Radiother Oncol 2012, 105:36-40.

W.C.J. Hunter, H.H. Barrett, T.K. Lewellen, R.S. Miyaoka, Multiple-Hit Parameter Estimation in Monolithic Detectors, IEEE Trans. Med. Imag., Vol 32, Issue 2, pp. 32–337, (2012), link.

R.K. Doot, B.F. Kurland, P.E. Kinahan, D.A. Mankoff, Design Considerations for using PET as a Response Measure in Single Site and Multicenter Clinical Trials, ACADEMIC RADIOLOGY 19. 184-190. 2012. link .

J.M. Marzluff, R. Miyaoka, S. Minoshima, D.J. Cross, Brain imaging reveals neuronal circuitry underlying the crow’s perception of human faces, Proceedings of the National Academy of Sciences 2012. link .

S. Bowen, M. Nyflot, M. Gensheimer, K.R. Hendrickson, P. Kinahan, G. Sandison, S. Patel, Challenges and opportunities in patient-specific, motion-managed and PET/CT-guided radiation therapy of lung cancer: review and perspective, Clinical and Translational Medicine 1. 18. 2012. link .

M. Abella, A.M. Alessio, D.A. Mankoff, L.R. MacDonald, J.J. Vaquero, M. Desco, P.E. Kinahan, Accuracy of CT-based attenuation correction in PET/CT bone imaging, Phys Med Biol 57. 2477-2490. 2012. link .

E.O. Aboagye, F.J. Gilbert, I.N. Fleming, A.J. Beer, V.J. Cunningham, P.K. Marsden, D. Visvikis, A.D. Gee, A.M. Groves, L.M. Kenny, G.J. Cook, P.E. Kinahan, M. Myers, L. Clarke, Recommendations for measurement of tumour vascularity with positron emission tomography in early phase clinical trials, Eur Radiol 22. 1465-1478. 2012. link .

T. Chapman, J.O. Swanson, G.S. Phillips, M.T. Parisi, A.M. Alessio, Pediatric chest CT radiation dose reduction: protocol refinement based on noise injection for pulmonary nodule detection accuracy, Clinical imaging Clinical imaging Clin Imaging 2012. link .

R.K. Doot, T. Thompson, B.E. Greer, K.C. Allberg, H.M. Linden, D.A. Mankoff, P.E. Kinahan, Early experiences in establishing a regional quantitative imaging network for PET/CT clinical trials, Magn Reson Imaging 2012. link .

S. Gu, G. Chakraborty, K. Champley, A.M. Alessio, J. Claridge, R. Rockne, M. Muzi, K.A. Krohn, A.M. Spence, E.C.J. Alvord, A.R. Anderson, P.E. Kinahan, K.R. Swanson, Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images, Math Med Biol 29. 31-48. 2012. link .

W. Kerwin, A. Alessio, M. Ferguson, T. Hatsukami, J. Caldwell, R. Miyaoka, T. Kohler, C. Yuan, High-resolution [18]fluorodeoxyglucose-positron emission tomography and coregistered magnetic resonance imaging of atherosclerotic plaque from a patient undergoing carotid endarterectomy, Circ Cardiovasc Imaging 5. 683-684. 2012. link .

X.L. Li, W.C.J. Hunter, T.K. Lewellen, R.S. Miyaoka, Use of Cramer-Rao Lower Bound for Performance Evaluation of Different Monolithic Crystal PET Detector Designs, Ieee T Nucl Sci 59. 3-12. 2012. link .

L.R. Macdonald, C.L. Wang, M. Eissa, D. Haseley, M.M. Kelly, F. Liu, J.R. Parikh, J.D. Beatty, J.V. Rogers, Positron emission mammography (PEM): effect of activity concentration, object size, and object contrast on phantom lesion detection, Med Phys 39. 6499-6508. 2012. link .

M. Muzi, F. O'Sullivan, D.A. Mankoff, R.K. Doot, L.A. Pierce, B.F. Kurland, H.M. Linden, P.E. Kinahan, Quantitative assessment of dynamic PET imaging data in cancer imaging, Magn Reson Imaging 2012. link .

L. Pierce, R. Miyaoka, T. Lewellen, A. Alessio, P. Kinahan, Detector Position Estimation for PET Scanners, Nucl Instrum Methods Phys Res A 677. 74-79. 2012. link .

D.A. Plotnik, C. Asher, S.K. Chu, R.S. Miyaoka, G.G. Garwin, B.W. Johnson, T. Li, K.A. Krohn, J.L. Schwartz, Levels of human equilibrative nucleoside transporter-1 are higher in proliferating regions of A549 tumor cells grown as tumor xenografts in vivo, Nucl Med Biol 39. 1161-1166. 2012. link .

Swanson, J., A. Alessio, T. Chapman, Estimated additional lifetime risk of cancer attributable to diagnostic CT in a pediatric bone marrow transplant cohort: Experience at a single academic institution, Open Journal of Clinical Diagnostics 2. 4-9. 2012. link .

T. Xia, A.M. Alessio, B. De Man, R. Manjeshwar, E. Asma, P.E. Kinahan, Ultra-low dose CT attenuation correction for PET/CT, PHYSICS IN MEDICINE AND BIOLOGY 57. 309-328. 2012. link .


S. R. Bowen, A. J. van der Kogel, M. Nordsmark, S. M. Bentzen and R. Jeraj, “Characterization of PET hypoxia tracer uptake and tissue oxygenation via electrochemical modeling,” Nucl Med Biol 38, 771-780 (2011).

K.M. Champley, L.R. MacDonald, T.K. Lewellen, R.S. Miyaoka, P.E. Kinahan, DOI-based reconstruction algorithms for a compact breast PET scanner, MEDICAL PHYSICS 38. 1660-1671. 2011. link .

S. Tong, A.M. Alessio, P.E. Kinahan, Image reconstruction for PET/CT scanners: past achievements and future challenges, Imaging Med 2. 529-545. 2010. link .

C. Liu, A.M. Alessio, P.E. Kinahan, Respiratory motion correction for quantitative PET/CT using all detected events with internal-external motion correlation, MEDICAL PHYSICS 38. 2715-2723. 2011. link .

C.M. Lockhart, L.R. MacDonald, A.M. Alessio, W.A. McDougald, R.K. Doot, P.E. Kinahan, Quantifying and Reducing the Effect of Calibration Error on Variability of PET/CT Standardized Uptake Value Measurements, JOURNAL OF NUCLEAR MEDICINE 52. 218-224. 2011. link .

L.R. MacDonald, S. Kohlmyer, C. Liu, T.K. Lewellen, P.E. Kinahan, Effects of MR surface coils on PET quantification, MEDICAL PHYSICS 38. 2948-2956. 2011. link .

R.S. Miyaoka, X.L. Li, W. Hunter, L.A. Pierce, W. McDougald, P.E. Kinahan, T.K. Lewellen, Resolution Properties of a Prototype Continuous Miniature Crystal Element (cMiCE) Scanner, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 58. 2244-2249. 2011. link .

W.C.J. Hunter, H.H. Barrett, R.S. Miyaoka, T.K. Lewellen, Multiple-hit parameter estimation in monolithic detectors, Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE 2224-2229. 2011. link .

S. Tong, A.M. Alessio, P.E. Kinahan, H. Liu, P. Shi, A robust state-space kinetics-guided framework for dynamic PET image reconstruction, PHYSICS IN MEDICINE AND BIOLOGY 56. 2481-2498. 2011. link .

S. Tong, A.M. Alessio, K. Thielemans, C. Stearns, S. Ross, P.E. Kinahan, Properties and Mitigation of Edge Artifacts in PSF-Based PET Reconstruction, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 58. 2264-2275. 2011. link .

R.S. Miyaoka, X.L. Li, W. Hunter, L.A. Pierce, W. McDougald, P.E. Kinahan, T.K. Lewellen, Resolution Properties of a Prototype Continuous Miniature Crystal Element (cMiCE) Scanner, Ieee T Nucl Sci 58. 2244-2249. 2011. link .

X.L. Li, C. Lockhart, T.K. Lewellen, R.S. Miyaoka, Study of PET Detector Performance With Varying SiPM Parameters and Readout Schemes, Ieee T Nucl Sci 58. 590-596. 2011. link .

N.G. Johnson-Williams, R.S. Miyaoka, X.L. Li, T.K. Lewellen, S. Hauck, Design of a Real Time FPGA-Based Three Dimensional Positioning Algorithm, Ieee T Nucl Sci 58. 26-33. 2011. link .

L. Xiaoli, C. Lockhart, T.K. Lewellen, R.S. Miyaoka, Study of PET Detector Performance With Varying SiPM Parameters and Readout Schemes, Nuclear Science, IEEE Transactions on 58. 590-596. 2011. link .

A.M. Alessio, M. Sammer, G.S. Phillips, V. Manchanda, B.C. Mohr, M.T. Parisi, Evaluation of optimal acquisition duration or injected activity for pediatric 18F-FDG PET/CT, J Nucl Med 52. 1028-1034. 2011. link .

L.R. MacDonald, R.L. Harrison, A.M. Alessio, W.C. Hunter, T.K. Lewellen, P.E. Kinahan, Effective count rates for PET scanners with reduced and extended axial field of view, Phys Med Biol 56. 3629-3643. 2011. link .

M.B. Sammer, B.L. Shulkin, A. Alessio, M.T. Parisi, Role of limited whole-body PET/CT in pediatric lymphoma, AJR Am J Roentgenol 196. 1047-1055. 2011. link .

C. Liu, A.M. Alessio, P.E. Kinahan, Respiratory motion correction for quantitative PET/CT using all detected events with internal-external motion correlation, Med Phys 38. 2715-2723. 2011. link .

J.L. Busch, A.M. Alessio, J.H. Caldwell, M. Gupta, S. Mao, J. Kadakia, W. Shuman, M.J. Budoff, K.R. Branch, Myocardial hypo-enhancement on resting computed tomography angiography images accurately identifies myocardial hypoperfusion, J Cardiovasc Comput Tomogr 5. 412-420. 2011. link .


A.M. Alessio, C.W. Stearns, S. Tong, S.G. Ross, S. Kohlmyer, A. Ganin, P.E. Kinahan, Application and Evaluation of a Measured Spatially Variant System Model for PET Image Reconstruction, IEEE TRANSACTIONS ON MEDICAL IMAGING 29. 938-949. 2010. link .

A.M. Alessio, E. Butterworth, J.H. Caldwell, J.B. Bassingthwaighte, Quantitative imaging of coronary blood flow, Nano Rev 1. 2010. link .

A.M. Alessio, P.E. Kinahan, K.M. Champley, J.H. Caldwell, Attenuation-emission alignment in cardiac PET/CT based on consistency conditions, MEDICAL PHYSICS 37. 1191-1200. 2010. link .

D.L. Chen, P.E. Kinahan, Multimodality Molecular Imaging of the Lung, JOURNAL OF MAGNETIC RESONANCE IMAGING 32. 1409-1420. 2010. link .

K.M. Champley, R.R. Raylman, P.E. Kinahan, Advancements to the planogram frequency-distance rebinning algorithm, INVERSE PROBLEMS 26. 045008. 2010. link .

R.K. Doot, J.S. Scheuermann, P.E. Christian, J.S. Karp, P.E. Kinahan, Instrumentation factors affecting variance and bias of quantifying tracer uptake with PET/CT, MEDICAL PHYSICS 37. 6035-6046. 2010. link .

F.H. Fahey, P.E. Kinahan, R.K. Doot, M. Kocak, H. Thurston, T.Y. Poussaint, Variability in PET quantitation within a multicenter consortium, MEDICAL PHYSICS 37. 3660-3666. 2010. link .

P.E. Kinahan, J.W. Fletcher, Positron Emission Tomography-Computed Tomography Standardized Uptake Values in Clinical Practice and Assessing Response to Therapy, SEMINARS IN ULTRASOUND CT AND MRI 31. 496-505. 2010. link .

C. Liu, A. Alessio, L. Pierce, K. Thielemans, S. Wollenweber, A. Ganin, P. Kinahan, Quiescent period respiratory gating for PET/CT, MEDICAL PHYSICS 37. 5037-5043. 2010. link .

K.R. Swanson, S. Gu, G. Chakraborty, A. Alessio, J. Claridge, R.C. Rockne, M. Muzi, K.A. Krohn, A.M. Spence, E.C. Alvord, A.R. Anderson, P. Kinahan, IN SILICO PET IMAGING: FROM ANATOMIC GLIOMA GROWTH DYNAMICS TO METABOLIC TUMOR ACTIVITY VIA BIO-MATHEMATICAL MODELING, NEURO-ONCOLOGY 12. 118-118. 2010. link .

R.S. Miyaoka, X.L. Li, C. Lockhart, T.K. Lewellen, Comparison of Detector Intrinsic Spatial Resolution Characteristics for Sensor on the Entrance Surface and Conventional Readout Designs, Ieee T Nucl Sci 57. 990-997. 2010. link .

S. Tong, A.M. Alessio, P.E. Kinahan, Noise and signal properties in PSF-based fully 3D PET image reconstruction: an experimental evaluation, PHYSICS IN MEDICINE AND BIOLOGY 55. 1453-1473. 2010. link .

R.S. Miyaoka, T. Ling, C. Lockhart, X.L. Li, T.K. Lewellen, Calibration Procedure for a Continuous Miniature Crystal Element (cMiCE) Detector, Ieee T Nucl Sci 57. 1023-1028. 2010. link .

D. DeWitt, N.G. Johnson-Williams, R.S. Miyaoka, X.L. Li, C. Lockhart, T.K. Lewellen, S. Hauck, Design of an FPGA-Based Algorithm for Real-Time Solutions of Statistics-Based Positioning, Ieee T Nucl Sci 57. 71-77. 2010. link .

A. Le Pogam, ALESSIO A, KANDEL B, KIROV A, BARRETT O, FERNANDEZ P, CHEZE-LE REST Catherine, VISVIKIS Dimitris, Comparison of PET reconstruction resolution recovery and post-reconstruction deconvolution for partial volume effect correction (PVC) in PET, Journal of nuclear medicine (JNM) 51. 557. 2010. link .

T.K. Lewellen, R.S. Miyaoka, L.R. MacDonald, D. DeWitt, M. Haselman, S. Hauck, Evolution of the design of a second generation FireWire based data acquisition system, Nuclear Science Symposium Conference Record (NSS/MIC), 2010 IEEE 2510-2514. 2010. link .

T.K. Lewellen, The challenge of detector designs for PET, AJR Am J Roentgenol 195. 301-309. 2010. link .

J.B. Bassingthwaighte, G.M. Raymond, E. Butterworth, A. Alessio, J.H. Caldwell, Multiscale modeling of metabolism, flows, and exchanges in heterogeneous organs, Ann N Y Acad Sci 1188. 111-120. 2010. link .

T. Xia, A.M. Alessio, P.E. Kinahan, Noise and Bias Properties of Monoenergetic Images from DECT used for Attenuation Correction with PET/CT and SPECT/CT, Proc Soc Photo Opt Instrum Eng 7622. 762225-762228. 2010. link .

A.M. Alessio, G.S. Phillips, A pediatric CT dose and risk estimator, Pediatr Radiol 40. 1816-1821. 2010. link .

M.J. Gelfand, S.E. Sharp, S.T. Treves, F.H. Fahey, M.T. Parisi, A.M. Alessio, Estimated cumulative radiation dose from PET/CT in children with malignancies, Pediatr Radiol 40. 1712-3; author reply 1714-5. 2010. link .


A.M. Alessio, P.E. Kinahan, V. Manchanda, V. Ghioni, L. Aldape, M.T. Parisi, Weight-Based, Low-Dose Pediatric Whole-Body PET/CT Protocols, JOURNAL OF NUCLEAR MEDICINE 50. 1570-1578. 2009. link .

K.M. Champley, T.K. Lewellen, L.R. MacDonald, R.S. Miyaoka, P.E. Kinahan, Statistical LOR estimation for a high-resolution dMiCE PET detector, PHYSICS IN MEDICINE AND BIOLOGY 54. 6369-6382. 2009. link .

P.E. Kinahan, R.K. Doot, M. Wanner-Roybal, L.M. Bidaut, S.G. Armato, C.R. Meyer, G. McLennan, PET/CT Assessment of Response to Therapy: Tumor Change Measurement, Truth Data, and Error, TRANSLATIONAL ONCOLOGY 2. 223-230. 2009. link .

K. Lee, R.S. Miyaoka, T.K. Lewellen, A.M. Alessio, P.E. Kinahan, Impact on Image Noise of Incorporating Detector Blurring Into Image Reconstruction for a Small Animal PET Scanner, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 56. 2769-2776. 2009. link .

C. Liu, L.A. Pierce, A.M. Alessio, P.E. Kinahan, The impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging, PHYSICS IN MEDICINE AND BIOLOGY 54. 7345-7362. 2009. link .

C.R. Meyer, S.G. Armato, C.P. Fenimore, G. McLennan, L.M. Bidaut, D.P. Barboriak, M.A. Gavrielides, E.F. Jackson, M.F. McNitt-Gray, P.E. Kinahan, N. Petrick, B.S. Zhao, Quantitative Imaging to Assess Tumor Response to Therapy: Common Themes of Measurement, Truth Data, and Error Sources, TRANSLATIONAL ONCOLOGY 2. 198-210. 2009. link .

L. MacDonald, J. Edwards, T. Lewellen, D. Haseley, J. Rogers, P. Kinahan, Clinical Imaging Characteristics of the Positron Emission Mammography Camera: PEM Flex Solo II, JOURNAL OF NUCLEAR MEDICINE 50. 1666-1675. 2009. link .

J. Noh, J.A. Fessler, P.E. Kinahan, Statistical Sinogram Restoration in Dual-Energy CT for PET Attenuation Correction, IEEE TRANSACTIONS ON MEDICAL IMAGING 28. 1688-1702. 2009. link .

M. Haselman, S. Hauck, T.K. Lewellen, R.S. Miyaoka, FPGA-based pulse parameter discovery for positron emission tomography, Nuclear Science Symposium Conference Record (NSS/MIC), 2009 IEEE 2956-2961. 2009. link .

M. Haselman, N. Johnson-Williams, C. Jerde, M. Kim, S. Hauck, T.K. Lewellen, R. Miyaoka, FPGA vs. MPPA for Positron Emission Tomography pulse processing, Field-Programmable Technology, 2009. FPT 2009. International Conference on 231-238. 2009. link .

C. Liu, L.A.n. Pierce, A.M. Alessio, P.E. Kinahan, The impact of respiratory motion on tumor quantification and delineation in static PET/CT imaging, Phys Med Biol 54. 7345-7362. 2009. link .

E. Lin, A. Alessio, What are the basic concepts of temporal, contrast, and spatial resolution in cardiac CT?, J Cardiovasc Comput Tomogr 3. 403-408. 2009. link .


A.M. Alessio, R.E. Schmitz, L.R. MacDonald, S.D. Wollenweber, C.W. Stearns, S.G. Ross, A. Ganin, T.K. Lewellen, P.E. Kinahan, Image reconstruction for a partially collimated whole body PET scanner, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 55. 975-983. 2008. link .

F. Liu, C. Cuevas, A.A. Moss, O. Kolokythas, T.J. Dubinsky, P.E. Kinahan, Gas bubble motion artifact in MDCT, AMERICAN JOURNAL OF ROENTGENOLOGY 190. 294-299. 2008. link .

K. Champley, M. Defrise, R. Clackdoyle, R.R. Raylman, P.E. Kinahan, Planogram rebinning with the frequency-distance relationship, IEEE TRANSACTIONS ON MEDICAL IMAGING 27. 925-933. 2008. link .

R.R. Raylman, S. Majewski, M.F. Smith, J. Proffitt, W. Hammond, A. Srinivasan, J. McKisson, V. Popov, A. Weisenberger, C.O. Judy, B. Kross, S. Ramasubramanian, L.E. Banta, P.E. Kinahan, K. Champley, The positron emission mammography/tomography breast imaging and biopsy system (PEM/PET): design, construction and phantom-based measurements, PHYSICS IN MEDICINE AND BIOLOGY 53. 637-653. 2008. link .

R.R. Raylman, M.F. Smith, P.E. Kinahan, S. Majewski, Quantification of radiotracer uptake with a dedicated breast PET imaging system, MEDICAL PHYSICS 35. 4989-4997. 2008. link .

D. DeWitt, R. Miyaoka, S., Xiaoli, Li, C. Lockhart, T. Lewellen, K., S. Hauck, Design of an FPGA based algorithm for real-time solutions of Statistics-Based Positioning, Nuclear Science Symposium Conference Record, 2008. NSS '08. IEEE 5029-5035. 2008. link .
L. MacDonald, J. Edwards, T. Lewellen, J. Rogers, P. Kinahan, Clinical imaging characteristics of the positron emission mammography PEM Flex Solo II, Nuclear Science

R. Harrison, S. Gillispie, R. Schmitz, T. Lewellen, Modeling block detectors in SimSET, J Nucl Med 49 Suppl 1. 410P. 2008. link .

X. Li, C. Lockhart, T.K. Lewellen, R.S. Miyaoka, A high resolution, monolithic crystal, PET/MRI detector with DOI positioning capability, Conf Proc IEEE Eng Med Biol Soc 2008. 2287-2290. 2008. link .

L.R. Macdonald, R.E. Schmitz, A.M. Alessio, S.D. Wollenweber, C.W. Stearns, A. Ganin, R.L. Harrison, T.K. Lewellen, P.E. Kinahan, Measured count-rate performance of the Discovery STE PET/CT scanner in 2D, 3D and partial collimation acquisition modes, Phys Med Biol 53. 3723-3738. 2008. link .

X. Jiang, H. Kenerson, L. Aicher, R. Miyaoka, J. Eary, J. Bissler, R.S. Yeung, The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake, Am J Pathol 172. 1748-1756. 2008. link .

A.M. Alessio, P.E. Kinahan, APPLICATION OF A SPATIALLY VARIANT SYSTEM MODEL FOR 3-D WHOLE-BODY PET IMAGE RECONSTRUCTION, Proc IEEE Int Symp Biomed Imaging 2008. 1315-1318. 2008. link .

T.K. Lewellen, R.S. Miyaoka, L.R. Macdonald, M. Haselman, D. Dewitt, W. Hunter, S. Hauck, Design of a Second Generation Firewire Based Data Acquisition System for Small Animal PET Scanners, IEEE Nucl Sci Symp Conf Rec (1997) 2008. 5023-5028. 2008. link .

R.S. Miyaoka, S.K. Joo, K. Lee, Detector Light Response Modeling for a Thick Continuous Slab Detector, J Nucl Sci Technol 45. 634-638. 2008. link .

T.K. Lewellen, Recent developments in PET detector technology, Phys Med Biol 53. R287-317. 2008. link .

T. Ling, T.H. Burnett, T.K. Lewellen, R.S. Miyaoka, Parametric positioning of a continuous crystal PET detector with depth of interaction decoding, Phys Med Biol 53. 1843-1863. 2008. link .


A. Alessio, K. Sauer, P. Kinahan, Statistical image reconstruction from correlated data with applications to PET, PHYSICS IN MEDICINE AND BIOLOGY 52. 6133-6150. 2007. link .

A.M. Alessio, S. Kohmyer, K. Branch, G. Chen, J. Caldwell, P. Kinahan, Cine CT for attenuation correction in cardiac PET/CT, JOURNAL OF NUCLEAR MEDICINE 48. 794-801. 2007. link .

G.P. Chen, K.R. Branch, A.M. Alessio, P. Pham, R. Tabibiazar, P. Kinahan, J.H. Caldwell, Effect of reconstruction algorithms on myocardial blood flow measurement with N-13-ammonia PET, JOURNAL OF NUCLEAR MEDICINE 48. 1259-1265. 2007. link .

R.K. Doot, L.K. Dunnwald, E.K. Schubert, M. Muzi, L.M. Peterson, P.E. Kinahan, B.F. Kurland, D.A. Mankoff, Dynamic and static approaches to quantifying F-18-FDG uptake for measuring cancer response to therapy, including the effect of granulocyte CSF, JOURNAL OF NUCLEAR MEDICINE 48. 920-925. 2007. link .

H.C. Gifford, P.E. Kinahan, C. Lartizien, M.A. King, Evaluation of multiclass model observers in PET LROC studies, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 54. 116-123. 2007. link .

T. Ling, T.K. Lewellen, R.S. Miyaoka, Depth of interaction decoding of a continuous crystal detector module, Phys Med Biol 52. 2213-2228. 2007. link .

R.S. Miyaoka, L. Tao, T.K. Lewellen, Effect of Number of Readout Channels on the Intrinsic Spatial Resolution Performance of a Continuous Miniature Crystal Element (cMiCE) Detector, Nuclear Science, IEEE Transactions on 54. 1561-1567. 2007. link .

R.E. Schmitz, R.L. Harrison, C.W. Stearns, T.K. Lewellen, P.E. Kinahan, Optimization of Noise Equivalent Count Rate Performance for a Partially Collimated PET Scanner by Varying the Number of Septa, Medical Imaging, IEEE Transactions on 26. 935-944. 2007. link

R.E. Schmitz, R.L. Harrison, C.W. Stearns, T.K. Lewellen, P.E. Kinahan, Optimization of noise equivalent count rate performance for a partially collimated PET scanner by varying the number of septa, IEEE Trans Med Imaging 26. 935-944. 2007. link

R.S. Miyaoka, T. Ling, T.K. Lewellen, Effect of Number of Readout Channels on the Intrinsic Spatial Resolution Performance of a Continuous Miniature Crystal Element (cMiCE) Detector, IEEE Trans Nucl Sci 54. 1561-1567. 2007. link


A. Alessio, K. Sauer, P. Kinahan, Analytical reconstruction of deconvolved Fourier rebinned PET sinograms, PHYSICS IN MEDICINE AND BIOLOGY 51. 77-93. 2006. link

A.M. Alessio, P.E. Kinahan, Improved quantitation for PET/CT image reconstruction with system modeling and anatomical priors, MEDICAL PHYSICS 33. 4095-4103. 2006. link

A.M. Alessio, P.E. Kinahan, T.K. Lewellen, Modeling and incorporation of system response functions in 3-D whole body PET, IEEE TRANSACTIONS ON MEDICAL IMAGING 25. 828-837. 2006. link

E.C. Ford, P.E. Kinahan, L. Hanlon, A. Alessio, J. Rajendran, D.L. Schwartz, M. Phillips, Tumor delineation using PET in head and neck cancers: Threshold contouring and lesion volumes, MEDICAL PHYSICS 33. 4280-4288. 2006. link

L.X. Gong, S. Pathak, A. Alessio, P. Kinahan, Automatic arm removal in PET and CT images for deformable registration, COMPUTERIZED MEDICAL IMAGING AND GRAPHICS 30. 469-477. 2006. link

L. Janeiro, C. Comtat, C. Lartizien, P.E. Kinahan, C. Michel, R. Trebossen, P. Almeida, Numerical observer studies comparing FORE plus AWOSEM, FORE plus NECOSEM, and NEC based fully 3-D OSEM for 3-D whole-body PET imaging, IEEE TRANSACTIONS ON NUCLEAR SCIENCE 53. 1194-1199. 2006. link

P.E. Kinahan, A.M. Alessio, J.A. Fessler, Dual energy CT attenuation correction methods for quantitative assessment of response to cancer therapy with PET/CT imaging, TECHNOLOGY IN CANCER RESEARCH & TREATMENT 5. 319-327. 2006. link

G.N. Mann, J.M. Link, P. Pham, C.A. Pickett, D.R. Byrd, P.E. Kinahan, K.A. Krohn, D.A. Mankoff, [C-11]Metahydroxyephedrine and [F-18]fluorodeoxyglucose positron emission tomography improve clinical decision making in suspected pheochromocytoma, ANNALS OF SURGICAL ONCOLOGY 13. 187-197. 2006. link

M.R. Tanas, M.L. Comstock, R.S. Miyaoka, J. Woodell, B.P. Rubin, A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E: Utility as a pre-clinical model, Modern Pathol 19. 294A-294A. 2006. link

T. Ling, K. Lee, R.S. Miyaoka, Performance comparisons of continuous miniature crystal element (cMiCE) detectors, Ieee T Nucl Sci 53. 2513-2518. 2006. link

R.E. Schmitz, P.E. Kinahan, R.L. Harrison, T.K. Lewellen, Simulations of the Effect of Collimation on Count Rates of an LSO PET System, IEEE Nucl Sci Symp Conf Rec (1997) 5. 3049-3052. 2006. link

L.R. Macdonald, R.E. Schmitz, A.M. Alessio, S.D. Wollenweber, C.W. Stearns, A. Ganin, R.L. Harrison, T.K. Lewellen, P.E. Kinahan, Count-Rate Performance of the Discovery STE PET Scanner Using Partial Collimation, IEEE Nucl Sci Symp Conf Rec (1997) 4. 2488-2493. 2006. link

P. Kinahan, H. Vesselle, J. Williams, C. Stearns, R. Schmitz, A. Alessio, L.M. Macdonald, Osama, T. Turkington, T. Lewellen, Performance evaluation of an integrated PET/CT scanner: Discovery STE, J NUCL MED 47. 392P-a. 2006. link

P. Kinahan, H. Vesselle, L. Macdonald, A. Alessio, S. Kohlmyer, T. Lewellen, Whole-body respiratory gated PET/CT, J NUCL MED 47. 187P-a-. 2006. link

B. Lewellen, D. Cross, S. Craft, L. Baker, T. Kosugi, H. Okada, T. Lewellen, P. Kinahan, S. Minoshima, Improved PET Detection of Focal Brain Activity Using Subset-dependent Relaxation `Dynamic' Row-action Maximum Likelihood Algorithm (DRAMA), Nuclear Science Symposium Conference Record, 2006. IEEE 4. 2177-2179. 2006. link

For a complete list of all publications feel free to reach out to any member of the team.

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