Past Meetings Spring 2000

March 29, 2000

Title: Inflation of the Type I Error Rate when both Additive and Multiplicative Interactions are Evaluated in Case-Control Studies
Speaker: Aimee Loarr
Summary:

March 29, 2000

Title: The Effects of Attrition on Conclusions Drawn from Longitudinal Data
Speaker: Jackie Starr
Summary:

April 5, 2000

Title: Mixture Models for Genetic Changes in Cancer Cells
Speaker: Manisha Desai
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April 12, 2000

Title: Self-Designing Optimal Group Sequential Clinical Trials
Speaker: Chau Thach
Summary:

April 26, 2000

Title: Insights on Bias and Information in Group-Level Studies
Speaker: Lianne Sheppard
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May 10, 2000

Title: The Analysis of Cytogenetic Data to Detect Chromosomal Abnormalities Associated With Cancer
Speaker: Scott Emerson
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May 17, 2000

Title: The Lymphoma Prognostic Index and Alternatives
Speaker: Michael LeBlanc
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May 24, 2000

Title: Accounting for Selection Bias in Observational Studies
Speaker: Rebecca Koperski
Summary:
Depression is a common mental illness and it is unclear what effect a mental health specialist has on improving depression symptoms. A main problem for this confusion is the fact that observational studies experience selection bias; those with more mental health specialist contact are sicker to begin with. The ideal situation would be to carry out a randomized clinical trial. If randomization is not possible, then it is important that correct results be obtained by these observational studies. The purpose of my thesis is to attempt to account for selection bias using various statistical methods in order to show the true effect of specialist referral on depression outcomes. In addition to analysis on actual data from the Physician Referral Study, a computer simulation was carried out in order to assess the performance of these methods. This talk will discuss the statistical methods used and present my findings.

Last Modification: 08 December 2000