MAPPFinder 2.0 Results for the Gene Ontology File: C:\Documents and Settings\yuxz\My Documents\GSD-Project\Output\DoseT24h-all\DoseT24h-all_Ratio_Mapp.gex Table: DoseT24h-all-Criterion0-GO Database: C:\GenMAPP 2 Data\Gene Databases\Rn-Std_20051114.gdb colors:|sig005| 11/24/2005 Rattus norvegicus Pvalues = true Calculation Summary: 173 probes met the [class] = 1 criteria. 81 probes meeting the filter linked to a Ensembl ID. 76 genes meeting the criterion linked to a GO term. 11212 Probes in this dataset 4023 Probes linked to a Ensembl ID. 2992 Genes linked to a GO term. The z score is based on an N of 2992 and a R of 76 distinct genes in the GO. GOID GO Name GO Type Number Changed Local Number Measured Local Number in GO Local Percent Changed Local Percent Present Local Number Changed Number Measured Number in GO Percent Changed Percent Present Z Score PermuteP AdjustedP 0009790 embryonic development P 1 3 5 33.33333 60 3 10 15 30 66.66666 5.527 0.002 1 0019867 outer membrane C 1 6 11 16.66667 54.54546 3 13 22 23.07692 59.09091 4.716 0.003 1 0043009 embryonic development (sensu Vertebrata) P 0 0 0 0 0 2 4 4 50 100 6.036 0.006 1 0009792 embryonic development (sensu Metazoa) P 0 0 0 0 0 2 4 4 50 100 6.036 0.006 1 0001701 embryonic development (sensu Mammalia) P 2 4 4 50 100 2 4 4 50 100 6.036 0.006 1 0006790 sulfur metabolism P 0 0 0 0 0 3 11 16 27.27273 68.75 5.222 0.006 1 0050777 negative regulation of immune response P 1 1 1 100 100 2 4 4 50 100 6.036 0.007 1 0050794 regulation of cellular process P 0 2 2 0 100 24 553 1247 4.339964 44.34643 2.979 0.007 1 0004930 G-protein coupled receptor activity F 0 32 62 0 51.6129 1 281 1492 0.3558719 18.83378 -2.444 0.014 1 0000087 M phase of mitotic cell cycle P 0 0 0 0 0 3 21 36 14.28571 58.33333 3.432 0.015 1 0007067 mitosis P 2 14 24 14.28571 58.33333 3 21 36 14.28571 58.33333 3.432 0.015 1 0051241 negative regulation of organismal physiological process P 0 0 0 0 0 2 6 6 33.33333 100 4.798 0.016 1 0051244 regulation of cellular physiological process P 0 0 0 0 0 22 517 1186 4.255319 43.5919 2.725 0.017 1 0042167 heme catabolism P 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0046329 negative regulation of JNK cascade P 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0030304 trypsin inhibitor activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0046149 pigment catabolism P 0 0 0 0 0 1 1 1 100 100 6.194 0.018 1 0046904 calcium oxalate binding F 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0019855 calcium channel inhibitor activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0030568 plasmin inhibitor activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0019862 IgA binding F 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0030236 anti-inflammatory response P 1 1 1 100 100 1 1 1 100 100 6.194 0.018 1 0005741 mitochondrial outer membrane C 2 7 10 28.57143 70 2 7 11 28.57143 63.63636 4.382 0.018 1 0004439 phosphoinositide 5-phosphatase activity F 1 1 2 100 50 1 1 2 100 50 6.194 0.02 1 0015887 pantothenate transport P 1 1 1 100 100 1 1 1 100 100 6.194 0.02 1 0017172 cysteine dioxygenase activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.021 1 0008892 guanine deaminase activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.021 1 0003955 NAD(P)H dehydrogenase (quinone) activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 6.194 0.021 1 0046439 L-cysteine metabolism P 1 1 1 100 100 1 1 1 100 100 6.194 0.021 1 0009913 epidermal cell differentiation P 0 0 0 0 0 1 1 2 100 50 6.194 0.022 1 0042471 ear morphogenesis P 0 0 0 0 0 1 1 1 100 100 6.194 0.022 1 0042490 mechanoreceptor differentiation P 0 0 0 0 0 1 1 2 100 50 6.194 0.022 1 0048729 tissue morphogenesis P 0 0 0 0 0 1 1 2 100 50 6.194 0.022 1 0007398 ectoderm development P 0 0 0 0 0 1 1 3 100 33.33333 6.194 0.022 1 0048730 epidermis morphogenesis P 0 0 0 0 0 1 1 2 100 50 6.194 0.022 1 0035315 hair cell differentiation P 0 0 0 0 0 1 1 2 100 50 6.194 0.022 1 0042491 auditory receptor cell differentiation P 0 0 0 0 0 1 1 2 100 50 6.194 0.022 1 0009912 auditory receptor cell fate commitment P 1 1 2 100 50 1 1 2 100 50 6.194 0.022 1 0042472 inner ear morphogenesis P 1 1 1 100 100 1 1 1 100 100 6.194 0.022 1 0008544 epidermis development P 0 0 1 0 0 1 1 3 100 33.33333 6.194 0.022 1 0050789 regulation of biological process P 0 0 0 0 0 25 613 1355 4.078303 45.23985 2.714 0.022 1 0007008 outer mitochondrial membrane organization and biogenesis P 1 1 1 100 100 1 1 1 100 100 6.194 0.023 1 0004217 cathepsin L activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.023 1 0006096 glycolysis P 3 17 56 17.64706 30.35714 3 21 61 14.28571 34.42623 3.432 0.023 1 0000278 mitotic cell cycle P 0 0 0 0 0 3 26 44 11.53846 59.09091 2.928 0.023 1 0004586 ornithine decarboxylase activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.024 1 0046839 phospholipid dephosphorylation P 1 1 11 100 9.090909 1 1 11 100 9.090909 6.194 0.024 1 0050791 regulation of physiological process P 0 0 1 0 0 23 558 1240 4.121864 45 2.632 0.024 1 0004285 proprotein convertase 1 activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.025 1 0016651 oxidoreductase activity\, acting on NADH or NADPH F 0 1 9 0 11.11111 2 11 42 18.18182 26.19048 3.303 0.025 1 0000279 M phase P 0 0 0 0 0 3 27 46 11.11111 58.69565 2.843 0.025 1 0016411 acylglycerol O-acyltransferase activity F 0 0 0 0 0 1 1 4 100 25 6.194 0.027 1 0004739 pyruvate dehydrogenase (acetyl-transferring) activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 6.194 0.027 1 0005967 pyruvate dehydrogenase complex (sensu Eukaryota) C 1 1 1 100 100 1 1 1 100 100 6.194 0.027 1 0016624 oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, disulfide as acceptor F 1 1 1 100 100 1 1 8 100 12.5 6.194 0.027 1 0003841 1-acylglycerol-3-phosphate O-acyltransferase activity F 1 1 3 100 33.33333 1 1 3 100 33.33333 6.194 0.027 1 0045254 pyruvate dehydrogenase complex C 0 0 1 0 0 1 1 2 100 50 6.194 0.027 1 0004738 pyruvate dehydrogenase activity F 0 0 0 0 0 1 1 3 100 33.33333 6.194 0.027 1 0008568 microtubule-severing ATPase activity F 1 1 2 100 50 1 1 2 100 50 6.194 0.028 1 0043028 caspase regulator activity F 0 0 0 0 0 1 1 1 100 100 6.194 0.028 1 0000299 integral to membrane of membrane fraction C 1 1 2 100 50 1 1 2 100 50 6.194 0.028 1 0043027 caspase inhibitor activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.028 1 0045333 cellular respiration P 1 2 2 50 100 2 10 16 20 62.5 3.514 0.028 1 0001584 rhodopsin-like receptor activity F 1 119 311 0.8403361 38.26366 1 246 1391 0.4065041 17.68512 -2.22 0.028 1 0004796 thromboxane-A synthase activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.029 1 0046655 folic acid metabolism P 1 1 1 100 100 1 1 1 100 100 6.194 0.029 1 0046500 S-adenosylmethionine metabolism P 1 1 1 100 100 1 1 1 100 100 6.194 0.029 1 0017174 glycine N-methyltransferase activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.029 1 0048185 activin binding F 1 1 1 100 100 1 1 1 100 100 6.194 0.029 1 0008374 O-acyltransferase activity F 0 0 0 0 0 2 9 16 22.22222 56.25 3.758 0.029 1 0008430 selenium binding F 2 9 15 22.22222 60 2 9 15 22.22222 60 3.758 0.032 1 0007166 cell surface receptor linked signal transduction P 0 10 21 0 47.61905 4 428 1753 0.9345794 24.41529 -2.28 0.032 1 0004357 glutamate-cysteine ligase activity F 1 2 2 50 100 1 2 2 50 100 4.267 0.033 1 0043118 negative regulation of physiological process P 0 0 0 0 0 6 94 147 6.382979 63.94558 2.406 0.033 1 0051301 cell division P 3 26 50 11.53846 52 3 28 52 10.71429 53.84615 2.762 0.034 1 0004888 transmembrane receptor activity F 0 12 30 0 40 3 374 1704 0.802139 21.94836 -2.283 0.035 1 0007154 cell communication P 1 9 19 11.11111 47.36842 13 853 2692 1.524033 31.68648 -2.23 0.036 1 0043170 macromolecule metabolism P 0 0 0 0 0 12 822 2694 1.459854 30.51225 -2.311 0.036 1 0004910 interleukin-1\, Type II\, blocking receptor activity F 1 1 2 100 50 1 1 2 100 50 6.194 0.037 1 0019968 interleukin-1\, Type II\, blocking binding F 0 0 0 0 0 1 1 2 100 50 6.194 0.037 1 0006355 regulation of transcription\, DNA-dependent P 13 275 757 4.727273 36.32761 14 300 790 4.666667 37.97468 2.468 0.037 1 0006351 transcription\, DNA-dependent P 0 0 0 0 0 14 300 799 4.666667 37.54693 2.468 0.037 1 0007186 G-protein coupled receptor protein signaling pathway P 1 263 1443 0.3802281 18.22592 3 340 1581 0.8823529 21.50538 -2.063 0.037 1 0051336 regulation of hydrolase activity P 0 0 0 0 0 2 10 20 20 50 3.514 0.038 1 0006007 glucose catabolism P 0 0 0 0 0 3 23 67 13.04348 34.32836 3.213 0.038 1 0048598 embryonic morphogenesis P 0 0 0 0 0 1 2 3 50 66.66666 4.267 0.039 1 0051187 cofactor catabolism P 0 0 0 0 0 2 12 18 16.66667 66.66666 3.116 0.039 1 0004857 enzyme inhibitor activity F 1 7 8 14.28571 87.5 5 65 148 7.692307 43.91892 2.669 0.039 1 0019320 hexose catabolism P 0 0 0 0 0 3 24 68 12.5 35.29412 3.113 0.04 1 0046365 monosaccharide catabolism P 0 0 0 0 0 3 24 68 12.5 35.29412 3.113 0.04 1 0045897 positive regulation of transcription\, mitotic P 0 0 0 0 0 1 2 2 50 100 4.267 0.042 1 0042475 odontogenesis (sensu Vertebrata) P 1 2 2 50 100 1 2 2 50 100 4.267 0.042 1 0046022 positive regulation of transcription from RNA polymerase II promoter\, mitotic P 1 2 2 50 100 1 2 2 50 100 4.267 0.042 1 0016248 channel inhibitor activity F 0 0 0 0 0 1 2 3 50 66.66666 4.267 0.042 1 0045896 regulation of transcription\, mitotic P 0 0 0 0 0 1 2 2 50 100 4.267 0.042 1 0008200 ion channel inhibitor activity F 0 0 0 0 0 1 2 3 50 66.66666 4.267 0.042 1 0046021 regulation of transcription from RNA polymerase II promoter\, mitotic P 0 0 0 0 0 1 2 2 50 100 4.267 0.042 1 0005001 transmembrane receptor protein tyrosine phosphatase activity F 1 2 2 50 100 1 2 2 50 100 4.267 0.044 1 0030060 L-malate dehydrogenase activity F 1 2 2 50 100 1 2 2 50 100 4.267 0.044 1 0019198 transmembrane receptor protein phosphatase activity F 0 0 0 0 0 1 2 2 50 100 4.267 0.044 1 0030258 lipid modification P 0 0 0 0 0 1 2 13 50 15.38461 4.267 0.044 1 0016747 transferase activity\, transferring groups other than amino-acyl groups F 0 0 0 0 0 3 28 74 10.71429 37.83784 2.762 0.044 1 0008415 acyltransferase activity F 2 20 51 10 39.21569 3 28 74 10.71429 37.83784 2.762 0.044 1 0051186 cofactor metabolism P 0 0 0 0 0 4 49 117 8.163265 41.88034 2.522 0.044 1 0015057 thrombin receptor activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 4.267 0.045 1 0046328 regulation of JNK cascade P 0 1 1 0 100 1 2 2 50 100 4.267 0.045 1 0046164 alcohol catabolism P 0 0 0 0 0 3 25 72 12 34.72222 3.018 0.045 1 0001660 fever P 1 2 2 50 100 1 2 2 50 100 4.267 0.046 1 0031649 heat generation P 0 0 0 0 0 1 2 2 50 100 4.267 0.046 1 0030521 androgen receptor signaling pathway P 1 2 2 50 100 1 2 2 50 100 4.267 0.046 1 0004463 leukotriene-A4 hydrolase activity F 0 0 1 0 0 1 2 3 50 66.66666 4.267 0.046 1 0004301 epoxide hydrolase activity F 1 2 2 50 100 1 2 2 50 100 4.267 0.046 1 0016654 oxidoreductase activity\, acting on NADH or NADPH\, disulfide as acceptor F 1 2 3 50 66.66666 1 2 3 50 66.66666 4.267 0.047 1 0016052 carbohydrate catabolism P 0 0 1 0 0 3 28 80 10.71429 35 2.762 0.047 1 0044275 cellular carbohydrate catabolism P 0 0 0 0 0 3 28 79 10.71429 35.44304 2.762 0.047 1 0016808 proprotein convertase activity F 0 0 0 0 0 1 2 2 50 100 4.267 0.048 1 0006805 xenobiotic metabolism P 2 11 11 18.18182 100 2 12 12 16.66667 100 3.116 0.048 1 0009410 response to xenobiotic stimulus P 0 0 1 0 0 2 12 13 16.66667 92.30769 3.116 0.048 1 0043280 positive regulation of caspase activity P 0 0 0 0 0 1 2 4 50 50 4.267 0.049 1 0008635 caspase activation via cytochrome c P 1 2 2 50 100 1 2 2 50 100 4.267 0.049 1 0006919 caspase activation P 0 0 2 0 0 1 2 4 50 50 4.267 0.049 1 0051345 positive regulation of hydrolase activity P 0 0 0 0 0 1 2 4 50 50 4.267 0.049 1 0043281 regulation of caspase activity P 0 0 0 0 0 1 2 4 50 50 4.267 0.049 1 0045944 positive regulation of transcription from RNA polymerase II promoter P 1 11 15 9.090909 73.33334 2 14 18 14.28571 77.77778 2.799 0.049 1 0016563 transcriptional activator activity F 3 25 35 12 71.42857 3 32 49 9.375 65.30612 2.47 0.053 1 0005968 Rab-protein geranylgeranyltransferase complex C 1 1 1 100 100 1 1 1 100 100 6.194 0.054 1 0005084 Rab escort protein activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.054 1 0004872 receptor activity F 5 319 754 1.567398 42.30769 6 509 2013 1.178782 25.28564 -2.142 0.054 1 0005546 phosphatidylinositol-4\,5-bisphosphate binding F 1 2 2 50 100 1 2 2 50 100 4.267 0.055 1 0015980 energy derivation by oxidation of organic compounds P 0 0 0 0 0 4 47 108 8.510638 43.51852 2.622 0.055 1 0016746 transferase activity\, transferring acyl groups F 0 0 0 0 0 3 31 80 9.67742 38.75 2.538 0.056 1 0030335 positive regulation of cell migration P 1 2 2 50 100 1 2 2 50 100 4.267 0.057 1 0048520 positive regulation of behavior P 0 0 0 0 0 1 2 2 50 100 4.267 0.057 1 0040017 positive regulation of locomotion P 0 0 0 0 0 1 2 2 50 100 4.267 0.057 1 0051272 positive regulation of cell motility P 0 0 0 0 0 1 2 2 50 100 4.267 0.057 1 0050776 regulation of immune response P 1 2 2 50 100 2 15 17 13.33333 88.23529 2.663 0.057 1 0043249 erythrocyte maturation P 1 2 2 50 100 1 2 2 50 100 4.267 0.058 1 0006760 folic acid and derivative metabolism P 0 0 0 0 0 1 2 6 50 33.33333 4.267 0.058 1 0005543 phospholipid binding F 0 5 6 0 83.33334 2 15 23 13.33333 65.21739 2.663 0.059 1 0004060 arylamine N-acetyltransferase activity F 1 1 2 100 50 1 1 2 100 50 6.194 0.063 1 0030371 translation repressor activity F 1 1 1 100 100 1 1 1 100 100 6.194 0.063 1 0004634 phosphopyruvate hydratase activity F 1 3 5 33.33333 60 1 3 5 33.33333 60 3.391 0.064 1 0000015 phosphopyruvate hydratase complex C 1 3 5 33.33333 60 1 3 5 33.33333 60 3.391 0.064 1 0030518 steroid hormone receptor signaling pathway P 0 0 0 0 0 1 3 5 33.33333 60 3.391 0.066 1 0030522 intracellular receptor-mediated signaling pathway P 0 0 1 0 0 1 3 6 33.33333 50 3.391 0.066 1 0006595 polyamine metabolism P 0 0 0 0 0 1 3 6 33.33333 50 3.391 0.066 1 0006596 polyamine biosynthesis P 1 2 4 50 50 1 3 5 33.33333 60 3.391 0.066 1 0018298 protein-chromophore linkage P 1 3 3 33.33333 100 1 3 3 33.33333 100 3.391 0.068 1 0008243 plasminogen activator activity F 1 3 5 33.33333 60 1 3 5 33.33333 60 3.391 0.069 1 0043283 biopolymer metabolism P 0 0 0 0 0 6 473 1499 1.268499 31.55437 -1.915 0.069 1 0016803 ether hydrolase activity F 0 0 0 0 0 1 3 4 33.33333 75 3.391 0.07 1 0042577 lipid phosphatase activity F 0 0 0 0 0 1 3 4 33.33333 75 3.391 0.071 1 0009306 protein secretion P 1 2 4 50 50 1 3 5 33.33333 60 3.391 0.072 1 0004791 thioredoxin-disulfide reductase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 3.391 0.073 1 0006534 cysteine metabolism P 0 0 0 0 0 1 3 3 33.33333 100 3.391 0.073 1 0016668 oxidoreductase activity\, acting on sulfur group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 1 3 5 33.33333 60 3.391 0.073 1 0008195 phosphatidate phosphatase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 3.391 0.073 1 0007049 cell cycle P 1 57 95 1.754386 60 6 116 204 5.172414 56.86274 1.838 0.073 1 0035091 phosphoinositide binding F 0 0 0 0 0 1 3 3 33.33333 100 3.391 0.074 1 0044267 cellular protein metabolism P 0 0 1 0 0 10 655 2123 1.526718 30.85257 -1.865 0.074 1 0001659 thermoregulation P 0 1 1 0 100 1 3 3 33.33333 100 3.391 0.075 1 0006006 glucose metabolism P 0 4 9 0 44.44444 3 31 78 9.67742 39.74359 2.538 0.075 1 0048523 negative regulation of cellular process P 0 0 0 0 0 6 110 171 5.454545 64.32748 1.979 0.075 1 0050672 negative regulation of lymphocyte proliferation P 1 1 1 100 100 1 2 2 50 100 4.267 0.076 1 0006108 malate metabolism P 1 3 4 33.33333 75 1 3 4 33.33333 75 3.391 0.076 1 0005112 Notch binding F 1 3 4 33.33333 75 1 3 4 33.33333 75 3.391 0.076 1 0016615 malate dehydrogenase activity F 0 0 0 0 0 1 3 4 33.33333 75 3.391 0.076 1 0045449 regulation of transcription P 0 27 86 0 31.39535 14 328 884 4.268293 37.10407 2.108 0.076 1 0042221 response to chemical stimulus P 0 0 0 0 0 5 87 130 5.747127 66.92308 1.929 0.077 1 0044260 cellular macromolecule metabolism P 0 0 0 0 0 10 664 2147 1.506024 30.92687 -1.92 0.077 1 0008285 negative regulation of cell proliferation P 1 13 15 7.692307 86.66666 2 15 17 13.33333 88.23529 2.663 0.078 1 0019219 regulation of nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism P 0 0 0 0 0 14 330 889 4.242424 37.12036 2.083 0.078 1 0051243 negative regulation of cellular physiological process P 0 0 0 0 0 5 88 137 5.681818 64.23357 1.901 0.078 1 0019538 protein metabolism P 0 7 16 0 43.75 10 666 2145 1.501502 31.04895 -1.932 0.079 1 0008283 cell proliferation P 1 24 31 4.166667 77.41936 4 65 80 6.153846 81.25 1.872 0.08 1 0005615 extracellular space C 5 86 127 5.813953 67.71654 5 90 134 5.555555 67.16418 1.846 0.081 1 0004861 cyclin-dependent protein kinase inhibitor activity F 1 2 3 50 66.66666 1 2 3 50 66.66666 4.267 0.082 1 0030218 erythrocyte differentiation P 0 1 1 0 100 1 3 3 33.33333 100 3.391 0.082 1 0045893 positive regulation of transcription\, DNA-dependent P 0 4 6 0 66.66666 2 18 24 11.11111 75 2.318 0.083 1 0005542 folic acid binding F 1 2 5 50 40 1 2 5 50 40 4.267 0.084 1 0004709 MAP kinase kinase kinase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 3.391 0.084 1 0003676 nucleic acid binding F 4 98 655 4.081633 14.96183 18 463 1783 3.887689 25.96747 2.004 0.085 1 0016416 O-palmitoyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 3.391 0.086 1 0016409 palmitoyltransferase activity F 0 0 0 0 0 1 3 3 33.33333 100 3.391 0.086 1 0004095 carnitine O-palmitoyltransferase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 3.391 0.086 1 0042558 pteridine and derivative metabolism P 0 0 0 0 0 1 4 8 25 50 2.856 0.086 1 0030097 hemopoiesis P 1 4 4 25 100 2 18 22 11.11111 81.81818 2.318 0.086 1 0048534 hemopoietic or lymphoid organ development P 0 0 0 0 0 2 18 22 11.11111 81.81818 2.318 0.086 1 0005740 mitochondrial membrane C 0 4 8 0 50 3 40 82 7.5 48.78049 2.007 0.086 1 0050795 regulation of behavior P 0 0 0 0 0 1 3 7 33.33333 42.85714 3.391 0.087 1 0040012 regulation of locomotion P 0 0 0 0 0 1 3 7 33.33333 42.85714 3.391 0.087 1 0051180 vitamin transport P 0 0 0 0 0 1 3 3 33.33333 100 3.391 0.087 1 0051270 regulation of cell motility P 0 0 0 0 0 1 3 7 33.33333 42.85714 3.391 0.087 1 0030334 regulation of cell migration P 0 1 4 0 25 1 3 7 33.33333 42.85714 3.391 0.087 1 0006749 glutathione metabolism P 0 0 1 0 0 1 4 5 25 80 2.856 0.088 1 0006750 glutathione biosynthesis P 1 4 4 25 100 1 4 4 25 100 2.856 0.088 1 0009405 pathogenesis P 1 4 6 25 66.66666 1 4 6 25 66.66666 2.856 0.09 1 0044419 interaction between organisms P 0 0 0 0 0 1 4 7 25 57.14286 2.856 0.09 1 0044404 symbiotic interaction between host and other organism P 0 0 0 0 0 1 4 7 25 57.14286 2.856 0.09 1 0044403 symbiosis\, mutualism through parasitism P 0 0 0 0 0 1 4 7 25 57.14286 2.856 0.09 1 0046483 heterocycle metabolism P 0 0 0 0 0 2 18 38 11.11111 47.36842 2.318 0.09 1 0005626 insoluble fraction C 1 3 4 33.33333 75 1 3 4 33.33333 75 3.391 0.092 1 0006787 porphyrin catabolism P 0 0 0 0 0 1 4 4 25 100 2.856 0.093 1 0042127 regulation of cell proliferation P 0 9 13 0 69.23077 3 42 50 7.142857 84 1.909 0.093 1 0008191 metalloendopeptidase inhibitor activity F 1 4 6 25 66.66666 1 4 6 25 66.66666 2.856 0.094 1 0007243 protein kinase cascade P 1 19 23 5.263158 82.6087 3 39 48 7.692307 81.25 2.058 0.094 1 0006955 immune response P 1 65 132 1.538462 49.24242 7 141 258 4.964539 54.65116 1.874 0.094 1 0016801 hydrolase activity\, acting on ether bonds F 0 0 0 0 0 1 4 5 25 80 2.856 0.097 1 0051250 negative regulation of lymphocyte activation P 0 0 0 0 0 1 3 3 33.33333 100 3.391 0.1 1 0050866 negative regulation of cell activation P 0 0 0 0 0 1 3 3 33.33333 100 3.391 0.1 1 0019885 antigen processing\, endogenous antigen via MHC class I P 1 4 7 25 57.14286 1 4 7 25 57.14286 2.856 0.101 1 0006350 transcription P 10 156 254 6.410256 61.41732 14 337 920 4.154303 36.63044 1.999 0.102 1 0001709 cell fate determination P 1 4 5 25 80 1 4 5 25 80 2.856 0.103 1 0004984 olfactory receptor activity F 0 102 1034 0 9.864603 0 102 1034 0 9.864603 -1.659 0.104 1 0045454 cell redox homeostasis P 1 4 7 25 57.14286 1 4 8 25 50 2.856 0.105 1 0015935 small ribosomal subunit C 1 5 20 20 25 1 5 20 20 25 2.483 0.105 1 0016406 carnitine O-acyltransferase activity F 0 0 0 0 0 1 4 5 25 80 2.856 0.106 1 0001664 G-protein-coupled receptor binding F 1 5 8 20 62.5 2 24 40 8.333333 60 1.811 0.106 1 0000074 regulation of progression through cell cycle P 3 36 67 8.333333 53.73134 4 67 114 5.970149 58.77193 1.804 0.108 1 0004022 alcohol dehydrogenase activity F 1 3 7 33.33333 42.85714 1 3 7 33.33333 42.85714 3.391 0.109 1 0050660 FAD binding F 1 5 14 20 35.71429 1 5 14 20 35.71429 2.483 0.11 1 0031323 regulation of cellular metabolism P 0 0 0 0 0 14 353 922 3.966006 38.28633 1.813 0.111 1 0003677 DNA binding F 6 151 469 3.97351 32.19616 13 321 928 4.049844 34.59052 1.819 0.112 1 0045941 positive regulation of transcription P 0 5 9 0 55.55556 2 22 32 9.090909 68.75 1.96 0.115 1 0006814 sodium ion transport P 3 45 68 6.666667 66.17647 3 45 68 6.666667 66.17647 1.772 0.115 1 0019834 phospholipase A2 inhibitor activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 3.391 0.116 1 0006092 main pathways of carbohydrate metabolism P 0 0 1 0 0 3 37 92 8.108109 40.21739 2.166 0.119 1 0005149 interleukin-1 receptor binding F 1 4 6 25 66.66666 1 5 10 20 50 2.483 0.12 1 0004457 lactate dehydrogenase activity F 0 0 0 0 0 1 5 6 20 83.33334 2.483 0.12 1 0004459 L-lactate dehydrogenase activity F 1 5 6 20 83.33334 1 5 6 20 83.33334 2.483 0.12 1 0006952 defense response P 0 4 19 0 21.05263 7 155 289 4.516129 53.63322 1.605 0.12 1 0017124 SH3 domain binding F 1 5 6 20 83.33334 1 5 6 20 83.33334 2.483 0.121 1 0050896 response to stimulus P 0 0 0 0 0 14 368 669 3.804348 55.00747 1.646 0.121 1 0019318 hexose metabolism P 0 0 0 0 0 3 39 98 7.692307 39.79592 2.058 0.122 1 0005246 calcium channel regulator activity F 0 3 5 0 60 1 4 6 25 66.66666 2.856 0.123 1 0042168 heme metabolism P 0 0 0 0 0 1 5 8 20 62.5 2.483 0.123 1 0006732 coenzyme metabolism P 0 0 0 0 0 3 43 105 6.976744 40.95238 1.862 0.124 1 0009607 response to biotic stimulus P 0 2 9 0 22.22222 7 157 299 4.458599 52.50836 1.569 0.126 1 0019966 interleukin-1 binding F 0 0 0 0 0 1 5 6 20 83.33334 2.483 0.127 1 0004908 interleukin-1 receptor activity F 0 2 2 0 100 1 5 6 20 83.33334 2.483 0.127 1 0030155 regulation of cell adhesion P 1 4 7 25 57.14286 1 5 8 20 62.5 2.483 0.127 1 0007007 inner mitochondrial membrane organization and biogenesis P 1 1 1 100 100 1 6 7 16.66667 85.71429 2.201 0.127 1 0007006 mitochondrial membrane organization and biogenesis P 0 0 0 0 0 1 6 7 16.66667 85.71429 2.201 0.127 1 0045935 positive regulation of nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism P 0 0 0 0 0 2 23 33 8.695652 69.69697 1.883 0.127 1 0045165 cell fate commitment P 0 0 0 0 0 1 5 6 20 83.33334 2.483 0.128 1 0007565 pregnancy P 1 5 6 20 83.33334 1 5 6 20 83.33334 2.483 0.128 1 0015280 amiloride-sensitive sodium channel activity F 1 5 6 20 83.33334 1 5 6 20 83.33334 2.483 0.129 1 0005996 monosaccharide metabolism P 0 0 0 0 0 3 40 99 7.5 40.40404 2.007 0.129 1 0004663 Rab-protein geranylgeranyltransferase activity F 1 3 3 33.33333 100 1 3 3 33.33333 100 3.391 0.134 1 0008632 apoptotic program P 0 0 0 0 0 1 5 8 20 62.5 2.483 0.134 1 0001516 prostaglandin biosynthesis P 1 5 7 20 71.42857 1 5 7 20 71.42857 2.483 0.134 1 0046457 prostanoid biosynthesis P 0 0 0 0 0 1 5 7 20 71.42857 2.483 0.134 1 0005794 Golgi apparatus C 0 11 25 0 44 0 109 179 0 60.89386 -1.717 0.134 1 0007165 signal transduction P 2 252 453 0.7936508 55.62914 12 698 2368 1.719198 29.47635 -1.574 0.135 1 0004859 phospholipase inhibitor activity F 1 2 2 50 100 1 4 4 25 100 2.856 0.139 1 0042476 odontogenesis P 0 5 6 0 83.33334 1 7 8 14.28571 87.5 1.977 0.139 1 0048519 negative regulation of biological process P 0 0 0 0 0 6 122 190 4.918033 64.21053 1.704 0.141 1 0006778 porphyrin metabolism P 0 0 0 0 0 1 6 11 16.66667 54.54546 2.201 0.142 1 0005391 sodium\:potassium-exchanging ATPase activity F 1 6 6 16.66667 100 1 6 6 16.66667 100 2.201 0.142 1 0000267 cell fraction C 0 0 0 0 0 5 93 135 5.376344 68.88889 1.766 0.142 1 0019222 regulation of metabolism P 0 0 0 0 0 14 367 950 3.814714 38.63158 1.657 0.143 1 0000096 sulfur amino acid metabolism P 0 0 0 0 0 1 6 8 16.66667 75 2.201 0.148 1 0006575 amino acid derivative metabolism P 0 0 0 0 0 2 26 43 7.692307 60.46511 1.677 0.149 1 0003700 transcription factor activity F 7 156 430 4.487179 36.27907 7 157 431 4.458599 36.42691 1.569 0.149 1 0016667 oxidoreductase activity\, acting on sulfur group of donors F 0 0 0 0 0 1 6 9 16.66667 66.66666 2.201 0.15 1 0015036 disulfide oxidoreductase activity F 1 4 8 25 50 1 6 11 16.66667 54.54546 2.201 0.154 1 0007005 mitochondrion organization and biogenesis P 0 1 1 0 100 1 7 9 14.28571 77.77778 1.977 0.154 1 0004289 subtilase activity F 1 7 9 14.28571 77.77778 1 7 9 14.28571 77.77778 1.977 0.158 1 0019865 immunoglobulin binding F 0 0 0 0 0 1 6 8 16.66667 75 2.201 0.16 1 0009636 response to toxin P 1 5 5 20 100 1 6 6 16.66667 100 2.201 0.16 1 0030246 carbohydrate binding F 0 0 1 0 0 0 85 163 0 52.14724 -1.51 0.16 1 0006693 prostaglandin metabolism P 0 1 1 0 100 1 6 8 16.66667 75 2.201 0.161 1 0006692 prostanoid metabolism P 0 0 0 0 0 1 6 8 16.66667 75 2.201 0.161 1 0044272 sulfur compound biosynthesis P 0 0 0 0 0 1 7 8 14.28571 87.5 1.977 0.162 1 0015457 auxiliary transport protein activity F 0 0 0 0 0 1 6 13 16.66667 46.15385 2.201 0.163 1 0016247 channel regulator activity F 0 0 0 0 0 1 6 13 16.66667 46.15385 2.201 0.163 1 0045202 synapse C 0 28 34 0 82.35294 0 89 109 0 81.65137 -1.546 0.164 1 0009059 macromolecule biosynthesis P 0 0 0 0 0 1 139 577 0.7194245 24.09012 -1.397 0.165 1 0050670 regulation of lymphocyte proliferation P 0 1 1 0 100 1 6 7 16.66667 85.71429 2.201 0.166 1 0015075 ion transporter activity F 0 7 8 0 87.5 4 298 539 1.342282 55.28757 -1.385 0.166 1 0007254 JNK cascade P 0 5 6 0 83.33334 1 7 8 14.28571 87.5 1.977 0.168 1 0031098 stress-activated protein kinase signaling pathway P 0 0 0 0 0 1 7 8 14.28571 87.5 1.977 0.168 1 0016773 phosphotransferase activity\, alcohol group as acceptor F 0 7 14 0 50 2 206 497 0.9708738 41.44869 -1.483 0.168 1 0016903 oxidoreductase activity\, acting on the aldehyde or oxo group of donors F 0 0 0 0 0 1 7 42 14.28571 16.66667 1.977 0.169 1 0007205 protein kinase C activation P 1 6 14 16.66667 42.85714 1 6 14 16.66667 42.85714 2.201 0.17 1 0019965 interleukin binding F 0 0 0 0 0 1 7 9 14.28571 77.77778 1.977 0.171 1 0004907 interleukin receptor activity F 0 0 1 0 0 1 7 9 14.28571 77.77778 1.977 0.171 1 0006357 regulation of transcription from RNA polymerase II promoter P 0 12 13 0 92.30769 2 29 35 6.896552 82.85714 1.498 0.171 1 0009069 serine family amino acid metabolism P 0 0 0 0 0 1 8 18 12.5 44.44444 1.793 0.173 1 0042440 pigment metabolism P 0 0 0 0 0 1 6 9 16.66667 66.66666 2.201 0.174 1 0005623 cell C 0 0 0 0 0 51 2211 6940 2.306648 31.85879 -1.365 0.176 1 0050790 regulation of enzyme activity P 0 0 0 0 0 2 26 44 7.692307 59.09091 1.677 0.179 1 0006352 transcription initiation P 1 3 9 33.33333 33.33333 1 7 17 14.28571 41.17647 1.977 0.18 1 0007259 JAK-STAT cascade P 1 3 3 33.33333 100 1 6 6 16.66667 100 2.201 0.181 1 0004860 protein kinase inhibitor activity F 0 1 2 0 50 1 7 10 14.28571 70 1.977 0.181 1 0030234 enzyme regulator activity F 0 2 4 0 50 6 134 291 4.477612 46.04811 1.458 0.181 1 0016765 transferase activity\, transferring alkyl or aryl (other than methyl) groups F 0 0 0 0 0 2 26 42 7.692307 61.90476 1.677 0.182 1 0006259 DNA metabolism P 0 4 10 0 40 0 81 280 0 28.92857 -1.473 0.184 1 0031325 positive regulation of cellular metabolism P 0 0 0 0 0 2 28 39 7.142857 71.79487 1.555 0.185 1 0046651 lymphocyte proliferation P 0 0 0 0 0 1 7 9 14.28571 77.77778 1.977 0.186 1 0004661 protein geranylgeranyltransferase activity F 0 0 0 0 0 1 5 5 20 100 2.483 0.187 1 0019439 aromatic compound catabolism P 1 2 3 50 66.66666 1 8 10 12.5 80 1.793 0.187 1 0004437 inositol or phosphatidylinositol phosphatase activity F 0 4 18 0 22.22222 1 8 25 12.5 32 1.793 0.188 1 0006725 aromatic compound metabolism P 0 4 22 0 18.18182 2 29 74 6.896552 39.18919 1.498 0.189 1 0051249 regulation of lymphocyte activation P 0 0 0 0 0 1 7 8 14.28571 87.5 1.977 0.19 1 0006100 tricarboxylic acid cycle intermediate metabolism P 0 3 4 0 75 1 8 10 12.5 80 1.793 0.19 1 0008170 N-methyltransferase activity F 0 3 15 0 20 1 7 25 14.28571 28 1.977 0.193 1 0005795 Golgi stack C 0 89 137 0 64.9635 0 91 139 0 65.46763 -1.564 0.195 1 0043087 regulation of GTPase activity P 1 7 15 14.28571 46.66667 1 7 15 14.28571 46.66667 1.977 0.196 1 0008080 N-acetyltransferase activity F 0 5 16 0 31.25 1 8 23 12.5 34.78261 1.793 0.196 1 0016410 N-acyltransferase activity F 0 0 0 0 0 1 8 25 12.5 32 1.793 0.196 1 0016301 kinase activity F 1 58 109 1.724138 53.21101 3 240 570 1.25 42.10526 -1.324 0.196 1 0043234 protein complex C 0 26 52 0 50 6 403 1281 1.488834 31.4598 -1.442 0.196 1 0046356 acetyl-CoA catabolism P 0 0 0 0 0 1 8 14 12.5 57.14286 1.793 0.199 1 0006099 tricarboxylic acid cycle P 1 8 14 12.5 57.14286 1 8 14 12.5 57.14286 1.793 0.199 1 0009060 aerobic respiration P 0 0 0 0 0 1 8 14 12.5 57.14286 1.793 0.199 1 0009109 coenzyme catabolism P 0 0 0 0 0 1 8 14 12.5 57.14286 1.793 0.199 1 0009628 response to abiotic stimulus P 0 0 0 0 0 5 101 147 4.950495 68.70748 1.566 0.201 1 0016020 membrane C 11 641 1381 1.716069 46.41564 28 1337 3798 2.094241 35.20274 -1.393 0.204 1 0016044 membrane organization and biogenesis P 0 2 2 0 100 1 9 10 11.11111 90 1.636 0.205 1 0048518 positive regulation of biological process P 0 0 0 0 0 5 106 135 4.716981 78.51852 1.45 0.205 1 0019210 kinase inhibitor activity F 0 1 1 0 100 1 8 11 12.5 72.72727 1.793 0.206 1 0046456 icosanoid biosynthesis P 0 0 0 0 0 1 8 12 12.5 66.66666 1.793 0.206 1 0050865 regulation of cell activation P 0 0 0 0 0 1 8 9 12.5 88.88889 1.793 0.208 1 0019722 calcium-mediated signaling P 1 7 9 14.28571 77.77778 1 8 10 12.5 80 1.793 0.209 1 0008207 C21-steroid hormone metabolism P 0 0 0 0 0 1 9 11 11.11111 81.81818 1.636 0.209 1 0006700 C21-steroid hormone biosynthesis P 1 9 11 11.11111 81.81818 1 9 11 11.11111 81.81818 1.636 0.209 1 0005544 calcium-dependent phospholipid binding F 1 8 15 12.5 53.33333 1 8 15 12.5 53.33333 1.793 0.216 1 0030333 antigen processing P 0 1 1 0 100 1 8 18 12.5 44.44444 1.793 0.216 1 0042401 biogenic amine biosynthesis P 0 0 0 0 0 1 10 17 10 58.82353 1.502 0.216 1 0009893 positive regulation of metabolism P 0 0 0 0 0 2 31 43 6.451613 72.09303 1.391 0.216 1 0044265 cellular macromolecule catabolism P 0 0 0 0 0 3 59 158 5.084746 37.34177 1.254 0.221 1 0044248 cellular catabolism P 0 0 0 0 0 5 108 247 4.62963 43.7247 1.405 0.224 1 0016310 phosphorylation P 0 2 3 0 66.66666 2 192 480 1.041667 40 -1.364 0.225 1 0005759 mitochondrial matrix C 0 8 10 0 80 1 11 16 9.090909 68.75 1.383 0.227 1 0030286 dynein complex C 1 6 11 16.66667 54.54546 1 9 14 11.11111 64.28571 1.636 0.228 1 0007611 learning and/or memory P 1 8 8 12.5 100 1 10 10 10 100 1.502 0.228 1 0008318 protein prenyltransferase activity F 0 2 5 0 40 1 7 10 14.28571 70 1.977 0.229 1 0006366 transcription from RNA polymerase II promoter P 0 2 6 0 33.33333 2 34 48 5.882353 70.83334 1.246 0.229 1 0043085 positive regulation of enzyme activity P 0 2 4 0 50 1 9 16 11.11111 56.25 1.636 0.232 1 0007517 muscle development P 2 29 41 6.896552 70.7317 2 36 50 5.555555 72 1.157 0.235 1 0005737 cytoplasm C 2 117 283 1.709402 41.34275 14 736 1596 1.902174 46.11529 -1.267 0.236 1 0004871 signal transducer activity F 1 58 117 1.724138 49.57265 15 778 2488 1.928021 31.2701 -1.261 0.24 1 0001666 response to hypoxia P 1 11 15 9.090909 73.33334 1 11 15 9.090909 73.33334 1.383 0.242 1 0040007 growth P 0 5 12 0 41.66667 0 62 90 0 68.88889 -1.284 0.244 1 0019748 secondary metabolism P 0 0 0 0 0 1 10 14 10 71.42857 1.502 0.246 1 0019216 regulation of lipid metabolism P 1 3 3 33.33333 100 1 9 9 11.11111 100 1.636 0.25 1 0004713 protein-tyrosine kinase activity F 0 54 228 0 23.68421 0 67 250 0 26.8 -1.336 0.25 1 0050876 reproductive physiological process P 0 0 0 0 0 1 11 12 9.090909 91.66666 1.383 0.251 1 0048609 reproductive organismal physiological process P 0 0 0 0 0 1 11 12 9.090909 91.66666 1.383 0.251 1 0016043 cell organization and biogenesis P 0 1 5 0 20 4 294 689 1.360544 42.67054 -1.353 0.252 1 0006412 protein biosynthesis P 1 71 404 1.408451 17.57426 1 125 544 0.8 22.97794 -1.263 0.255 1 0005578 extracellular matrix (sensu Metazoa) C 1 38 76 2.631579 50 1 135 211 0.7407407 63.98104 -1.36 0.255 1 0031012 extracellular matrix C 0 1 12 0 8.333333 1 136 223 0.7352941 60.98655 -1.369 0.255 1 0016564 transcriptional repressor activity F 1 9 14 11.11111 64.28571 1 11 18 9.090909 61.11111 1.383 0.256 1 0006091 generation of precursor metabolites and energy P 0 2 3 0 66.66666 7 177 464 3.954802 38.14655 1.233 0.256 1 0016407 acetyltransferase activity F 0 0 1 0 0 1 11 31 9.090909 35.48387 1.383 0.258 1 0016311 dephosphorylation P 0 0 0 0 0 2 37 92 5.405406 40.21739 1.114 0.258 1 0016831 carboxy-lyase activity F 0 3 4 0 75 1 12 20 8.333333 60 1.278 0.26 1 0042165 neurotransmitter binding F 0 2 2 0 100 0 63 88 0 71.59091 -1.295 0.261 1 0030099 myeloid cell differentiation P 0 2 3 0 66.66666 1 11 13 9.090909 84.61539 1.383 0.262 1 0006084 acetyl-CoA metabolism P 0 1 2 0 50 1 11 18 9.090909 61.11111 1.383 0.264 1 0004659 prenyltransferase activity F 0 3 5 0 60 1 9 15 11.11111 60 1.636 0.266 1 0030594 neurotransmitter receptor activity F 0 33 40 0 82.5 0 61 86 0 70.93023 -1.274 0.267 1 0008092 cytoskeletal protein binding F 0 8 15 0 53.33333 0 68 152 0 44.73684 -1.346 0.268 1 0008654 phospholipid biosynthesis P 1 8 15 12.5 53.33333 1 11 23 9.090909 47.82609 1.383 0.271 1 0016616 oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor F 0 2 3 0 66.66666 2 35 64 5.714286 54.6875 1.2 0.271 1 0008324 cation transporter activity F 0 6 12 0 50 3 231 417 1.298701 55.39568 -1.248 0.272 1 0045892 negative regulation of transcription\, DNA-dependent P 1 7 10 14.28571 70 1 11 20 9.090909 55 1.383 0.274 1 0009117 nucleotide metabolism P 0 10 18 0 55.55556 0 60 135 0 44.44444 -1.263 0.274 1 0016814 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in cyclic amidines F 0 0 1 0 0 1 11 19 9.090909 57.89474 1.383 0.275 1 0005874 microtubule C 2 34 72 5.882353 47.22222 2 34 72 5.882353 47.22222 1.246 0.279 1 0042398 amino acid derivative biosynthesis P 0 0 0 0 0 1 13 22 7.692307 59.09091 1.183 0.279 1 0016079 synaptic vesicle exocytosis P 1 7 8 14.28571 87.5 1 13 15 7.692307 86.66666 1.183 0.284 1 0016702 oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen\, incorporation of two atoms of oxygen F 0 6 11 0 54.54546 1 13 22 7.692307 59.09091 1.183 0.284 1 0051213 dioxygenase activity F 0 0 0 0 0 1 13 22 7.692307 59.09091 1.183 0.284 1 0019239 deaminase activity F 0 0 1 0 0 1 10 17 10 58.82353 1.502 0.291 1 0007050 cell cycle arrest P 1 12 17 8.333333 70.58823 1 12 17 8.333333 70.58823 1.278 0.291 1 0009986 cell surface C 1 12 19 8.333333 63.15789 1 13 21 7.692307 61.90476 1.183 0.291 1 0051239 regulation of organismal physiological process P 0 0 0 0 0 2 37 43 5.405406 86.04651 1.114 0.291 1 0006464 protein modification P 0 16 64 0 25 5 332 960 1.506024 34.58333 -1.27 0.291 1 0006690 icosanoid metabolism P 0 0 0 0 0 1 12 18 8.333333 66.66666 1.278 0.294 1 0016614 oxidoreductase activity\, acting on CH-OH group of donors F 0 0 1 0 0 2 37 69 5.405406 53.62319 1.114 0.296 1 0006953 acute-phase response P 1 13 16 7.692307 81.25 1 13 16 7.692307 81.25 1.183 0.297 1 0009987 cellular process P 0 0 0 0 0 58 2437 7980 2.379975 30.53885 -1.166 0.302 1 0007219 Notch signaling pathway P 1 12 18 8.333333 66.66666 1 13 19 7.692307 68.42105 1.183 0.303 1 0042803 protein homodimerization activity F 1 14 18 7.142857 77.77778 1 14 18 7.142857 77.77778 1.097 0.306 1 0016701 oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen F 0 0 0 0 0 1 14 23 7.142857 60.86956 1.097 0.307 1 0051242 positive regulation of cellular physiological process P 0 0 0 0 0 4 84 105 4.761905 80 1.313 0.311 1 0005624 membrane fraction C 1 15 18 6.666667 83.33334 4 86 125 4.651163 68.8 1.262 0.313 1 0006986 response to unfolded protein P 1 12 22 8.333333 54.54546 1 12 22 8.333333 54.54546 1.278 0.314 1 0006767 water-soluble vitamin metabolism P 0 0 0 0 0 1 12 24 8.333333 50 1.278 0.315 1 0048469 cell maturation P 0 0 0 0 0 1 15 17 6.666667 88.23529 1.018 0.315 1 0016772 transferase activity\, transferring phosphorus-containing groups F 0 0 0 0 0 4 263 655 1.520913 40.15267 -1.1 0.315 1 0007200 G-protein signaling\, coupled to IP3 second messenger (phospholipase C activating) P 0 3 3 0 100 1 14 23 7.142857 60.86956 1.097 0.318 1 0006468 protein amino acid phosphorylation P 2 159 398 1.257862 39.94975 2 167 407 1.197605 41.03194 -1.135 0.318 1 0004672 protein kinase activity F 0 8 27 0 29.62963 2 171 419 1.169591 40.81145 -1.173 0.319 1 0005272 sodium channel activity F 0 2 3 0 66.66666 1 13 16 7.692307 81.25 1.183 0.325 1 0000165 MAPKKK cascade P 0 1 1 0 100 1 14 17 7.142857 82.35294 1.097 0.331 1 0046649 lymphocyte activation P 0 0 1 0 0 1 15 22 6.666667 68.18182 1.018 0.332 1 0048522 positive regulation of cellular process P 0 0 0 0 0 4 92 113 4.347826 81.41593 1.119 0.334 1 0043119 positive regulation of physiological process P 0 0 0 0 0 4 90 113 4.444445 79.64602 1.166 0.337 1 0050662 coenzyme binding F 0 0 0 0 0 1 14 69 7.142857 20.28986 1.097 0.339 1 0042379 chemokine receptor binding F 0 0 0 0 0 1 18 28 5.555555 64.28571 0.815 0.34 1 0008009 chemokine activity F 1 18 28 5.555555 64.28571 1 18 28 5.555555 64.28571 0.815 0.34 1 0050817 coagulation P 0 0 0 0 0 1 18 34 5.555555 52.94118 0.815 0.345 1 0007596 blood coagulation P 1 16 26 6.25 61.53846 1 18 31 5.555555 58.06452 0.815 0.345 1 0007599 hemostasis P 0 0 0 0 0 1 18 31 5.555555 58.06452 0.815 0.345 1 0006811 ion transport P 3 167 221 1.796407 75.56561 5 298 555 1.677852 53.6937 -0.997 0.345 1 0016860 intramolecular oxidoreductase activity F 0 0 0 0 0 1 16 34 6.25 47.05882 0.946 0.346 1 0008757 S-adenosylmethionine-dependent methyltransferase activity F 0 6 30 0 20 1 15 54 6.666667 27.77778 1.018 0.347 1 0005215 transporter activity F 3 115 248 2.608696 46.37097 10 517 1074 1.934236 48.1378 -0.963 0.349 1 0048489 synaptic vesicle transport P 0 1 1 0 100 1 17 19 5.882353 89.47369 0.878 0.352 1 0005634 nucleus C 18 536 1577 3.358209 33.98859 18 563 1641 3.197158 34.30835 1.1 0.354 1 0004364 glutathione transferase activity F 1 14 24 7.142857 58.33333 1 14 24 7.142857 58.33333 1.097 0.355 1 0048015 phosphoinositide-mediated signaling P 0 1 1 0 100 1 16 25 6.25 64 0.946 0.355 1 0046467 membrane lipid biosynthesis P 0 0 0 0 0 1 14 27 7.142857 51.85185 1.097 0.357 1 0016836 hydro-lyase activity F 0 0 0 0 0 1 18 38 5.555555 47.36842 0.815 0.357 1 0019887 protein kinase regulator activity F 0 1 2 0 50 1 16 24 6.25 66.66666 0.946 0.358 1 0004896 hematopoietin/interferon-class (D200-domain) cytokine receptor activity F 0 8 19 0 42.10526 1 17 29 5.882353 58.62069 0.878 0.359 1 0006644 phospholipid metabolism P 0 1 3 0 33.33333 1 17 35 5.882353 48.57143 0.878 0.359 1 0007275 development P 0 62 150 0 41.33333 6 338 568 1.775148 59.50704 -0.949 0.362 1 0008284 positive regulation of cell proliferation P 1 11 13 9.090909 84.61539 1 17 19 5.882353 89.47369 0.878 0.363 1 0006979 response to oxidative stress P 1 10 26 10 38.46154 1 17 33 5.882353 51.51515 0.878 0.364 1 0007267 cell-cell signaling P 0 13 20 0 65 1 103 132 0.9708738 78.0303 -1.03 0.366 1 0016477 cell migration P 0 1 1 0 100 1 18 29 5.555555 62.06897 0.815 0.367 1 0005882 intermediate filament C 1 13 51 7.692307 25.4902 1 18 64 5.555555 28.125 0.815 0.369 1 0045111 intermediate filament cytoskeleton C 0 0 0 0 0 1 18 64 5.555555 28.125 0.815 0.369 1 0042446 hormone biosynthesis P 0 3 3 0 100 1 16 20 6.25 80 0.946 0.372 1 0006996 organelle organization and biogenesis P 0 0 0 0 0 1 111 339 0.9009009 32.74336 -1.118 0.372 1 0015662 ATPase activity\, coupled to transmembrane movement of ions\, phosphorylative mechanism F 0 3 14 0 21.42857 1 19 32 5.263158 59.375 0.757 0.374 1 0006752 group transfer coenzyme metabolism P 0 0 0 0 0 1 18 58 5.555555 31.03448 0.815 0.378 1 0043412 biopolymer modification P 0 0 0 0 0 6 340 994 1.764706 34.20523 -0.965 0.383 1 0030528 transcription regulator activity F 0 31 92 0 33.69565 8 222 584 3.603604 38.0137 1.047 0.387 1 0019207 kinase regulator activity F 0 0 0 0 0 1 18 26 5.555555 69.23077 0.815 0.388 1 0016757 transferase activity\, transferring glycosyl groups F 0 28 59 0 47.45763 0 57 144 0 39.58333 -1.23 0.39 1 0016830 carbon-carbon lyase activity F 0 0 0 0 0 1 17 28 5.882353 60.71429 0.878 0.394 1 0040008 regulation of growth P 0 4 7 0 57.14286 0 44 61 0 72.13115 -1.079 0.394 1 0008361 regulation of cell size P 0 0 0 0 0 0 48 64 0 75 -1.127 0.395 1 0016049 cell growth P 0 6 9 0 66.66666 0 48 64 0 75 -1.127 0.395 1 0045211 postsynaptic membrane C 0 58 72 0 80.55556 0 58 72 0 80.55556 -1.241 0.395 1 0007010 cytoskeleton organization and biogenesis P 0 10 23 0 43.47826 0 52 141 0 36.87943 -1.174 0.396 1 0019992 diacylglycerol binding F 1 16 21 6.25 76.19048 1 16 21 6.25 76.19048 0.946 0.398 1 0042623 ATPase activity\, coupled F 0 0 0 0 0 3 62 173 4.83871 35.83815 1.162 0.401 1 0005230 extracellular ligand-gated ion channel activity F 0 32 39 0 82.05128 0 46 58 0 79.31035 -1.103 0.402 1 0003779 actin binding F 0 48 112 0 42.85714 0 48 114 0 42.10526 -1.127 0.403 1 0012505 endomembrane system C 0 0 0 0 0 0 57 92 0 61.95652 -1.23 0.403 1 0005516 calmodulin binding F 0 51 69 0 73.91304 0 51 69 0 73.91304 -1.163 0.405 1 0016481 negative regulation of transcription P 0 7 14 0 50 1 18 34 5.555555 52.94118 0.815 0.407 1 0045934 negative regulation of nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism P 0 0 0 0 0 1 18 36 5.555555 50 0.815 0.407 1 0001558 regulation of cell growth P 0 28 38 0 73.68421 0 42 55 0 76.36364 -1.054 0.407 1 0005529 sugar binding F 0 57 118 0 48.30508 0 57 120 0 47.5 -1.23 0.407 1 0008509 anion transporter activity F 0 1 1 0 100 0 42 72 0 58.33333 -1.054 0.408 1 0006576 biogenic amine metabolism P 0 0 0 0 0 1 19 33 5.263158 57.57576 0.757 0.41 1 0015674 di-\, tri-valent inorganic cation transport P 0 0 0 0 0 0 54 88 0 61.36364 -1.197 0.41 1 0009165 nucleotide biosynthesis P 0 5 7 0 71.42857 0 54 114 0 47.36842 -1.197 0.411 1 0005783 endoplasmic reticulum C 2 120 203 1.666667 59.1133 2 142 238 1.408451 59.66386 -0.878 0.416 1 0016209 antioxidant activity F 0 4 4 0 100 1 19 40 5.263158 47.5 0.757 0.418 1 0008237 metallopeptidase activity F 0 17 40 0 42.5 0 51 133 0 38.34586 -1.163 0.418 1 0044249 cellular biosynthesis P 0 2 4 0 50 5 278 835 1.798561 33.29342 -0.825 0.42 1 0004842 ubiquitin-protein ligase activity F 0 44 216 0 20.37037 0 44 216 0 20.37037 -1.079 0.42 1 0031410 cytoplasmic vesicle C 0 0 0 0 0 0 58 91 0 63.73626 -1.241 0.422 1 0016023 cytoplasmic membrane-bound vesicle C 0 2 3 0 66.66666 0 58 91 0 63.73626 -1.241 0.422 1 0051649 establishment of cellular localization P 0 0 0 0 0 2 148 334 1.351351 44.31138 -0.943 0.429 1 0046907 intracellular transport P 0 1 2 0 50 2 148 334 1.351351 44.31138 -0.943 0.429 1 0051641 cellular localization P 0 0 0 0 0 2 148 334 1.351351 44.31138 -0.943 0.429 1 0009057 macromolecule catabolism P 0 0 0 0 0 3 68 174 4.411765 39.08046 0.992 0.431 1 0016887 ATPase activity F 1 27 67 3.703704 40.29851 3 72 205 4.166667 35.12195 0.888 0.434 1 0008610 lipid biosynthesis P 0 1 4 0 25 3 68 116 4.411765 58.62069 0.992 0.435 1 0006766 vitamin metabolism P 0 0 0 0 0 1 17 29 5.882353 58.62069 0.878 0.436 1 0005875 microtubule associated complex C 0 6 33 0 18.18182 1 17 53 5.882353 32.07547 0.878 0.437 1 0043285 biopolymer catabolism P 0 0 0 0 0 0 41 97 0 42.26804 -1.041 0.437 1 0015077 monovalent inorganic cation transporter activity F 0 2 2 0 100 0 44 113 0 38.93805 -1.079 0.437 1 0030135 coated vesicle C 0 0 0 0 0 0 40 68 0 58.82353 -1.028 0.439 1 0008289 lipid binding F 0 31 57 0 54.38596 3 66 116 4.545455 56.89655 1.047 0.448 1 0044238 primary metabolism P 0 0 0 0 0 30 1337 4025 2.243829 33.21739 -0.926 0.448 1 0015078 hydrogen ion transporter activity F 0 3 4 0 75 0 41 110 0 37.27273 -1.041 0.448 1 0005198 structural molecule activity F 1 54 177 1.851852 30.50847 2 150 610 1.333333 24.59016 -0.964 0.453 1 0006519 amino acid and derivative metabolism P 0 1 1 0 100 3 73 164 4.109589 44.5122 0.863 0.456 1 0044262 cellular carbohydrate metabolism P 0 0 0 0 0 3 68 165 4.411765 41.21212 0.992 0.458 1 0016791 phosphoric monoester hydrolase activity F 0 1 7 0 14.28571 3 73 154 4.109589 47.4026 0.863 0.458 1 0005524 ATP binding F 6 317 888 1.892744 35.6982 6 317 888 1.892744 35.6982 -0.775 0.459 1 0006066 alcohol metabolism P 0 0 0 0 0 3 70 152 4.285714 46.05263 0.939 0.463 1 0042981 regulation of apoptosis P 2 27 41 7.407407 65.85366 3 78 106 3.846154 73.58491 0.743 0.464 1 0005739 mitochondrion C 5 148 236 3.378378 62.71186 6 168 290 3.571429 57.93103 0.874 0.468 1 0006950 response to stress P 0 13 17 0 76.47059 7 210 343 3.333333 61.22449 0.758 0.468 1 0005575 cellular_component C 0 0 0 0 0 58 2389 7427 2.427794 32.16642 -0.777 0.472 1 0008233 peptidase activity F 2 61 140 3.278688 43.57143 3 181 478 1.657459 37.86611 -0.779 0.476 1 0046914 transition metal ion binding F 0 0 0 0 0 6 324 1094 1.851852 29.61609 -0.834 0.485 1 0005515 protein binding F 6 289 652 2.076125 44.32515 16 731 1482 2.188782 49.32524 -0.694 0.488 1 0006793 phosphorus metabolism P 0 0 0 0 0 4 224 573 1.785714 39.09249 -0.746 0.5 1 0006796 phosphate metabolism P 0 0 4 0 0 4 224 573 1.785714 39.09249 -0.746 0.5 1 0008150 biological_process P 0 0 0 0 0 64 2617 8660 2.445548 30.2194 -0.868 0.503 1 0019226 transmission of nerve impulse P 0 0 0 0 0 1 86 107 1.162791 80.37383 -0.824 0.505 1 0005244 voltage-gated ion channel activity F 0 21 28 0 75 1 84 137 1.190476 61.31387 -0.797 0.507 1 0016491 oxidoreductase activity F 5 143 325 3.496504 44 7 209 535 3.349282 39.06542 0.771 0.51 1 0015267 channel or pore class transporter activity F 0 0 0 0 0 3 187 307 1.604278 60.91205 -0.84 0.512 1 0015268 alpha-type channel activity F 0 0 0 0 0 3 186 305 1.612903 60.98361 -0.83 0.514 1 0000287 magnesium ion binding F 1 81 113 1.234568 71.68142 1 81 113 1.234568 71.68142 -0.757 0.518 1 0007268 synaptic transmission P 0 31 38 0 81.57895 1 81 101 1.234568 80.19802 -0.757 0.518 1 0005886 plasma membrane C 2 51 63 3.921569 80.95238 4 232 385 1.724138 60.25974 -0.822 0.52 1 0043228 non-membrane-bound organelle C 0 0 0 0 0 4 233 869 1.716738 26.81243 -0.832 0.52 1 0043232 intracellular non-membrane-bound organelle C 0 0 0 0 0 4 233 869 1.716738 26.81243 -0.832 0.52 1 0045045 secretory pathway P 0 2 3 0 66.66666 1 80 112 1.25 71.42857 -0.743 0.526 1 0030529 ribonucleoprotein complex C 0 12 32 0 37.5 1 80 432 1.25 18.51852 -0.743 0.53 1 0007242 intracellular signaling cascade P 1 101 238 0.990099 42.43697 8 246 503 3.252033 48.90656 0.741 0.54 1 0048513 organ development P 0 0 0 0 0 4 116 157 3.448276 73.88535 0.634 0.562 1 0009058 biosynthesis P 0 16 35 0 45.71429 6 314 922 1.910828 34.0564 -0.749 0.564 1 0006605 protein targeting P 0 10 27 0 37.03704 0 32 70 0 45.71429 -0.918 0.576 1 0009056 catabolism P 0 1 1 0 100 5 144 305 3.472222 47.21312 0.729 0.58 1 0004674 protein serine/threonine kinase activity F 2 107 305 1.869159 35.08197 2 127 333 1.574803 38.13814 -0.706 0.584 1 0051246 regulation of protein metabolism P 0 0 0 0 0 0 32 52 0 61.53846 -0.918 0.587 1 0019752 carboxylic acid metabolism P 0 0 0 0 0 5 140 252 3.571429 55.55556 0.794 0.589 1 0006082 organic acid metabolism P 0 0 0 0 0 5 140 252 3.571429 55.55556 0.794 0.589 1 0005261 cation channel activity F 0 13 33 0 39.39394 2 130 202 1.538462 64.35644 -0.742 0.593 1 0050801 ion homeostasis P 0 0 1 0 0 0 31 56 0 55.35714 -0.903 0.593 1 0009889 regulation of biosynthesis P 0 0 0 0 0 0 30 39 0 76.92308 -0.889 0.604 1 0016758 transferase activity\, transferring hexosyl groups F 0 7 21 0 33.33333 0 36 89 0 40.44944 -0.974 0.607 1 0044255 cellular lipid metabolism P 0 0 0 0 0 5 140 235 3.571429 59.57447 0.794 0.608 1 0006417 regulation of protein biosynthesis P 0 1 1 0 100 0 24 31 0 77.41936 -0.794 0.609 1 0006873 cell ion homeostasis P 0 2 2 0 100 0 26 46 0 56.52174 -0.827 0.609 1 0050793 regulation of development P 0 2 4 0 50 0 34 53 0 64.15094 -0.947 0.609 1 0042592 homeostasis P 0 1 1 0 100 2 51 82 3.921569 62.19512 0.632 0.611 1 0031326 regulation of cellular biosynthesis P 0 0 0 0 0 0 26 33 0 78.78788 -0.827 0.611 1 0004518 nuclease activity F 0 4 8 0 50 0 29 89 0 32.58427 -0.873 0.611 1 0043037 translation P 0 0 0 0 0 0 29 105 0 27.61905 -0.873 0.611 1 0005231 excitatory extracellular ligand-gated ion channel activity F 0 0 0 0 0 0 31 37 0 83.78378 -0.903 0.611 1 0051276 chromosome organization and biogenesis P 0 2 5 0 40 0 39 131 0 29.77099 -1.015 0.614 1 0016788 hydrolase activity\, acting on ester bonds F 0 7 14 0 50 3 170 404 1.764706 42.07921 -0.662 0.615 1 0007167 enzyme linked receptor protein signaling pathway P 0 0 0 0 0 0 37 55 0 67.27273 -0.988 0.615 1 0003774 motor activity F 2 34 59 5.882353 57.62712 2 46 103 4.347826 44.66019 0.785 0.616 1 0030003 cation homeostasis P 0 0 0 0 0 0 24 44 0 54.54546 -0.794 0.617 1 0001501 skeletal development P 0 4 5 0 80 0 28 35 0 80 -0.858 0.617 1 0016567 protein ubiquitination P 0 36 188 0 19.14894 0 37 189 0 19.57672 -0.988 0.619 1 0016070 RNA metabolism P 0 0 0 0 0 0 39 184 0 21.19565 -1.015 0.619 1 0000003 reproduction P 0 0 1 0 0 2 48 78 4.166667 61.53846 0.722 0.62 1 0008066 glutamate receptor activity F 0 0 0 0 0 0 25 65 0 38.46154 -0.81 0.62 1 0000151 ubiquitin ligase complex C 0 33 185 0 17.83784 0 35 187 0 18.71658 -0.961 0.62 1 0019932 second-messenger-mediated signaling P 0 4 4 0 100 2 42 57 4.761905 73.68421 0.921 0.621 1 0017076 purine nucleotide binding F 0 0 0 0 0 9 425 1145 2.117647 37.1179 -0.597 0.622 1 0007001 chromosome organization and biogenesis (sensu Eukaryota) P 0 18 62 0 29.03226 0 36 123 0 29.26829 -0.974 0.623 1 0006163 purine nucleotide metabolism P 0 0 0 0 0 0 30 73 0 41.09589 -0.889 0.624 1 0006164 purine nucleotide biosynthesis P 0 3 6 0 50 0 30 73 0 41.09589 -0.889 0.624 1 0007169 transmembrane receptor protein tyrosine kinase signaling pathway P 0 16 30 0 53.33333 0 26 41 0 63.41463 -0.827 0.625 1 0051082 unfolded protein binding F 0 34 94 0 36.17021 0 34 94 0 36.17021 -0.947 0.625 1 0006508 proteolysis P 3 141 378 2.12766 37.30159 3 173 458 1.734104 37.77293 -0.694 0.626 1 0006812 cation transport P 1 69 122 1.449275 56.55738 4 198 375 2.020202 52.8 -0.481 0.627 1 0005262 calcium channel activity F 0 17 24 0 70.83334 0 29 42 0 69.04762 -0.873 0.627 1 0009259 ribonucleotide metabolism P 0 0 0 0 0 0 30 71 0 42.25352 -0.889 0.628 1 0009260 ribonucleotide biosynthesis P 0 0 0 0 0 0 30 71 0 42.25352 -0.889 0.628 1 0006917 induction of apoptosis P 0 21 27 0 77.77778 0 24 30 0 80 -0.794 0.629 1 0012502 induction of programmed cell death P 0 0 0 0 0 0 24 30 0 80 -0.794 0.629 1 0046849 bone remodeling P 0 1 2 0 50 0 25 31 0 80.64516 -0.81 0.629 1 0000785 chromatin C 0 9 43 0 20.93023 0 26 108 0 24.07407 -0.827 0.629 1 0050875 cellular physiological process P 0 0 0 0 0 55 2073 5883 2.65316 35.23713 0.59 0.63 1 0005694 chromosome C 0 14 37 0 37.83784 0 39 141 0 27.65957 -1.015 0.63 1 0006875 metal ion homeostasis P 0 1 1 0 100 0 22 41 0 53.65854 -0.76 0.631 1 0008565 protein transporter activity F 0 18 50 0 36 0 27 77 0 35.06493 -0.843 0.631 1 0045595 regulation of cell differentiation P 0 6 8 0 75 0 24 34 0 70.58823 -0.794 0.633 1 0005216 ion channel activity F 2 68 96 2.941176 70.83334 3 171 279 1.754386 61.29032 -0.672 0.634 1 0015294 solute\:cation symporter activity F 0 0 0 0 0 0 26 39 0 66.66666 -0.827 0.634 1 0006913 nucleocytoplasmic transport P 0 6 6 0 100 0 23 44 0 52.27273 -0.777 0.635 1 0006954 inflammatory response P 2 38 50 5.263158 76 2 47 61 4.255319 77.04918 0.753 0.636 1 0005554 molecular function unknown F 0 25 94 0 26.59575 0 25 94 0 26.59575 -0.81 0.636 1 0004222 metalloendopeptidase activity F 0 16 51 0 31.37255 0 31 72 0 43.05556 -0.903 0.636 1 0003924 GTPase activity F 0 22 45 0 48.88889 0 22 45 0 48.88889 -0.76 0.637 1 0008081 phosphoric diester hydrolase activity F 0 0 1 0 0 0 27 47 0 57.44681 -0.843 0.637 1 0019199 transmembrane receptor protein kinase activity F 0 0 0 0 0 0 22 41 0 53.65854 -0.76 0.638 1 0016789 carboxylic ester hydrolase activity F 0 2 3 0 66.66666 0 38 76 0 50 -1.001 0.638 1 0046873 metal ion transporter activity F 0 5 16 0 31.25 0 27 60 0 45 -0.843 0.639 1 0008194 UDP-glycosyltransferase activity F 0 0 0 0 0 0 23 40 0 57.5 -0.777 0.64 1 0009152 purine ribonucleotide biosynthesis P 0 0 1 0 0 0 28 68 0 41.17647 -0.858 0.64 1 0009150 purine ribonucleotide metabolism P 0 0 0 0 0 0 28 68 0 41.17647 -0.858 0.64 1 0030163 protein catabolism P 0 8 14 0 57.14286 0 39 91 0 42.85714 -1.015 0.64 1 0051049 regulation of transport P 0 0 0 0 0 0 21 24 0 87.5 -0.742 0.641 1 0006461 protein complex assembly P 0 8 12 0 66.66666 0 29 94 0 30.85106 -0.873 0.641 1 0006396 RNA processing P 0 4 28 0 14.28571 0 30 132 0 22.72727 -0.889 0.641 1 0006816 calcium ion transport P 0 38 54 0 70.37037 0 39 55 0 70.90909 -1.015 0.641 1 0005777 peroxisome C 0 27 34 0 79.41177 0 32 42 0 76.19048 -0.918 0.642 1 0042579 microbody C 0 0 0 0 0 0 32 42 0 76.19048 -0.918 0.642 1 0030136 clathrin-coated vesicle C 0 1 1 0 100 0 39 63 0 61.90476 -1.015 0.642 1 0043492 ATPase activity\, coupled to movement of substances F 0 0 0 0 0 2 48 99 4.166667 48.48485 0.722 0.643 1 0042626 ATPase activity\, coupled to transmembrane movement of substances F 1 15 24 6.666667 62.5 2 48 99 4.166667 48.48485 0.722 0.643 1 0050381 unspecific monooxygenase activity F 0 21 30 0 70 0 21 30 0 70 -0.742 0.643 1 0009719 response to endogenous stimulus P 0 0 0 0 0 0 39 87 0 44.82759 -1.015 0.643 1 0016820 hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances F 0 14 18 0 77.77778 2 50 102 4 49.01961 0.662 0.644 1 0030005 di-\, tri-valent inorganic cation homeostasis P 0 0 0 0 0 0 20 39 0 51.28205 -0.724 0.644 1 0015370 solute\:sodium symporter activity F 0 0 0 0 0 0 25 38 0 65.78947 -0.81 0.644 1 0016055 Wnt receptor signaling pathway P 0 17 22 0 77.27273 0 28 57 0 49.12281 -0.858 0.644 1 0016337 cell-cell adhesion P 0 8 11 0 72.72727 0 28 94 0 29.78723 -0.858 0.645 1 0043235 receptor complex C 0 0 0 0 0 0 33 51 0 64.70588 -0.932 0.645 1 0006323 DNA packaging P 0 1 9 0 11.11111 0 28 111 0 25.22523 -0.858 0.646 1 0006325 establishment and/or maintenance of chromatin architecture P 0 2 2 0 100 0 28 111 0 25.22523 -0.858 0.646 1 0015630 microtubule cytoskeleton C 0 2 2 0 100 2 45 110 4.444445 40.90909 0.818 0.647 1 0019899 enzyme binding F 0 3 3 0 100 0 26 46 0 56.52174 -0.827 0.648 1 0030247 polysaccharide binding F 0 0 0 0 0 0 30 47 0 63.82979 -0.889 0.648 1 0030145 manganese ion binding F 0 25 43 0 58.13953 0 25 43 0 58.13953 -0.81 0.649 1 0001871 pattern binding F 0 0 0 0 0 0 31 48 0 64.58334 -0.903 0.649 1 0007017 microtubule-based process P 0 4 5 0 80 0 23 79 0 29.11392 -0.777 0.65 1 0003824 catalytic activity F 9 254 2231 3.543307 11.38503 36 1326 5070 2.714932 26.15385 0.542 0.651 1 0016787 hydrolase activity F 6 215 371 2.790698 57.95148 11 509 1333 2.1611 38.18455 -0.596 0.652 1 0030414 protease inhibitor activity F 0 0 1 0 0 2 41 109 4.878049 37.61468 0.958 0.653 1 0004866 endopeptidase inhibitor activity F 0 3 5 0 60 2 41 109 4.878049 37.61468 0.958 0.653 1 0008021 synaptic vesicle C 0 17 26 0 65.38461 0 23 34 0 67.64706 -0.777 0.653 1 0044257 cellular protein catabolism P 0 0 0 0 0 0 30 76 0 39.47368 -0.889 0.653 1 0051603 proteolysis during cellular protein catabolism P 0 0 0 0 0 0 30 76 0 39.47368 -0.889 0.653 1 0016042 lipid catabolism P 0 26 42 0 61.90476 0 32 52 0 61.53846 -0.918 0.653 1 0016125 sterol metabolism P 0 0 1 0 0 0 25 32 0 78.125 -0.81 0.654 1 0048666 neuron development P 0 0 0 0 0 0 27 35 0 77.14286 -0.843 0.654 1 0006836 neurotransmitter transport P 0 25 34 0 73.52941 0 29 38 0 76.31579 -0.873 0.656 1 0005539 glycosaminoglycan binding F 0 0 0 0 0 0 29 43 0 67.44186 -0.873 0.657 1 0005496 steroid binding F 0 14 28 0 50 0 23 41 0 56.09756 -0.777 0.658 1 0006818 hydrogen transport P 0 0 0 0 0 0 28 65 0 43.07692 -0.858 0.658 1 0008227 amine receptor activity F 0 0 0 0 0 0 20 25 0 80 -0.724 0.659 1 0016298 lipase activity F 0 2 3 0 66.66666 0 26 51 0 50.98039 -0.827 0.659 1 0006974 response to DNA damage stimulus P 0 2 2 0 100 0 33 81 0 40.74074 -0.932 0.659 1 0048514 blood vessel morphogenesis P 0 0 0 0 0 0 22 29 0 75.86207 -0.76 0.662 1 0001525 angiogenesis P 0 17 21 0 80.95238 0 22 29 0 75.86207 -0.76 0.662 1 0001944 vasculature development P 0 0 0 0 0 0 22 29 0 75.86207 -0.76 0.662 1 0001568 blood vessel development P 0 1 1 0 100 0 22 29 0 75.86207 -0.76 0.662 1 0007606 sensory perception of chemical stimulus P 0 0 0 0 0 0 23 55 0 41.81818 -0.777 0.662 1 0015992 proton transport P 0 21 30 0 70 0 27 64 0 42.1875 -0.843 0.662 1 0005792 microsome C 2 55 85 3.636364 64.70588 2 55 85 3.636364 64.70588 0.521 0.664 1 0042598 vesicular fraction C 0 0 0 0 0 2 55 85 3.636364 64.70588 0.521 0.664 1 0008201 heparin binding F 0 25 34 0 73.52941 0 25 34 0 73.52941 -0.81 0.664 1 0008238 exopeptidase activity F 0 0 0 0 0 0 26 63 0 41.26984 -0.827 0.664 1 0030054 cell junction C 0 1 1 0 100 0 29 64 0 45.3125 -0.873 0.665 1 0019941 modification-dependent protein catabolism P 0 0 0 0 0 0 24 66 0 36.36364 -0.794 0.666 1 0006511 ubiquitin-dependent protein catabolism P 0 23 64 0 35.9375 0 24 66 0 36.36364 -0.794 0.666 1 0008203 cholesterol metabolism P 0 10 14 0 71.42857 0 23 29 0 79.31035 -0.777 0.667 1 0016071 mRNA metabolism P 0 1 1 0 100 0 23 72 0 31.94444 -0.777 0.667 1 0031214 biomineral formation P 0 0 0 0 0 0 21 26 0 80.76923 -0.742 0.668 1 0001503 ossification P 0 13 15 0 86.66666 0 21 26 0 80.76923 -0.742 0.668 1 0016798 hydrolase activity\, acting on glycosyl bonds F 0 13 22 0 59.09091 0 25 76 0 32.89474 -0.81 0.668 1 0006281 DNA repair P 0 16 51 0 31.37255 0 30 78 0 38.46154 -0.889 0.668 1 0005102 receptor binding F 1 6 10 16.66667 60 7 220 352 3.181818 62.5 0.628 0.669 1 0048193 Golgi vesicle transport P 0 1 1 0 100 0 24 39 0 61.53846 -0.794 0.67 1 0046906 tetrapyrrole binding F 0 0 0 0 0 2 55 101 3.636364 54.45544 0.521 0.672 1 0020037 heme binding F 2 55 101 3.636364 54.45544 2 55 101 3.636364 54.45544 0.521 0.672 1 0005085 guanyl-nucleotide exchange factor activity F 0 19 54 0 35.18518 0 20 55 0 36.36364 -0.724 0.675 1 0009141 nucleoside triphosphate metabolism P 0 0 0 0 0 0 23 60 0 38.33333 -0.777 0.676 1 0042995 cell projection C 0 1 1 0 100 0 21 30 0 70 -0.742 0.68 1 0006397 mRNA processing P 0 9 43 0 20.93023 0 21 68 0 30.88235 -0.742 0.681 1 0019829 cation-transporting ATPase activity F 0 2 2 0 100 0 24 54 0 44.44444 -0.794 0.681 1 0006869 lipid transport P 0 12 30 0 40 0 21 42 0 50 -0.742 0.682 1 0009142 nucleoside triphosphate biosynthesis P 0 0 0 0 0 0 22 59 0 37.28814 -0.76 0.683 1 0009206 purine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 0 22 58 0 37.93103 -0.76 0.683 1 0009199 ribonucleoside triphosphate metabolism P 0 0 0 0 0 0 22 58 0 37.93103 -0.76 0.683 1 0009144 purine nucleoside triphosphate metabolism P 0 0 0 0 0 0 22 58 0 37.93103 -0.76 0.683 1 0009205 purine ribonucleoside triphosphate metabolism P 0 0 0 0 0 0 22 58 0 37.93103 -0.76 0.683 1 0009201 ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 0 22 58 0 37.93103 -0.76 0.683 1 0009145 purine nucleoside triphosphate biosynthesis P 0 0 0 0 0 0 22 58 0 37.93103 -0.76 0.683 1 0009100 glycoprotein metabolism P 0 0 0 0 0 0 21 53 0 39.62264 -0.742 0.684 1 0005911 intercellular junction C 0 1 1 0 100 0 24 58 0 41.37931 -0.794 0.685 1 0051179 localization P 0 0 0 0 0 20 847 1829 2.361275 46.30946 -0.391 0.692 1 0006821 chloride transport P 0 20 38 0 52.63158 0 20 38 0 52.63158 -0.724 0.693 1 0005125 cytokine activity F 1 31 45 3.225806 68.88889 3 79 133 3.797468 59.39849 0.72 0.7 1 0043413 biopolymer glycosylation P 0 0 0 0 0 0 20 50 0 40 -0.724 0.7 1 0000902 cellular morphogenesis P 0 1 1 0 100 1 76 106 1.315789 71.69811 -0.687 0.703 1 0007582 physiological process P 0 9 11 0 81.81818 60 2289 6574 2.621232 34.81898 0.509 0.704 1 0030554 adenyl nucleotide binding F 0 0 0 0 0 7 331 917 2.114804 36.09597 -0.521 0.705 1 0006810 transport P 5 170 373 2.941176 45.57641 19 817 1778 2.325581 45.9505 -0.457 0.709 1 0005267 potassium channel activity F 0 26 36 0 72.22222 1 70 109 1.428571 64.22018 -0.598 0.709 1 0016627 oxidoreductase activity\, acting on the CH-CH group of donors F 0 1 1 0 100 0 20 27 0 74.07407 -0.724 0.71 1 0009611 response to wounding P 0 5 8 0 62.5 3 87 116 3.448276 75 0.546 0.715 1 0007264 small GTPase mediated signal transduction P 3 75 172 4 43.60465 3 79 179 3.797468 44.13408 0.72 0.716 1 0043067 regulation of programmed cell death P 0 0 0 0 0 3 79 107 3.797468 73.83178 0.72 0.717 1 0005840 ribosome C 0 52 328 0 15.85366 1 60 363 1.666667 16.52892 -0.434 0.719 1 0008083 growth factor activity F 2 71 96 2.816901 73.95834 3 85 120 3.529412 70.83334 0.588 0.721 1 0006820 anion transport P 0 11 15 0 73.33334 1 62 130 1.612903 47.69231 -0.469 0.724 1 0006512 ubiquitin cycle P 1 30 93 3.333333 32.25806 1 66 281 1.515152 23.48755 -0.535 0.726 1 0009613 response to pest\, pathogen or parasite P 0 5 10 0 50 3 87 124 3.448276 70.16129 0.546 0.728 1 0043226 organelle C 0 0 0 0 0 28 1164 3089 2.405498 37.6821 -0.373 0.729 1 0043229 intracellular organelle C 0 0 0 0 0 28 1164 3089 2.405498 37.6821 -0.373 0.729 1 0003735 structural constituent of ribosome F 1 64 373 1.5625 17.15818 1 64 373 1.5625 17.15818 -0.502 0.729 1 0005829 cytosol C 2 65 86 3.076923 75.5814 3 85 121 3.529412 70.24793 0.588 0.73 1 0043207 response to external biotic stimulus P 0 0 0 0 0 3 92 131 3.26087 70.229 0.446 0.738 1 0016874 ligase activity F 1 33 61 3.030303 54.09836 1 75 329 1.333333 22.79635 -0.673 0.744 1 0031090 organelle membrane C 0 0 0 0 0 3 93 171 3.225806 54.38596 0.427 0.746 1 0009653 morphogenesis P 0 0 0 0 0 2 112 158 1.785714 70.88608 -0.517 0.749 1 0042578 phosphoric ester hydrolase activity F 0 2 2 0 100 3 98 198 3.061224 49.49495 0.333 0.75 1 0006139 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism P 0 4 15 0 26.66667 14 501 1499 2.794411 33.42228 0.396 0.753 1 0006886 intracellular protein transport P 2 73 172 2.739726 42.44186 2 105 237 1.904762 44.3038 -0.421 0.767 1 0005386 carrier activity F 0 6 10 0 60 3 148 322 2.027027 45.96273 -0.407 0.768 1 0016192 vesicle-mediated transport P 0 22 28 0 78.57143 2 117 159 1.709402 73.58491 -0.582 0.768 1 0005856 cytoskeleton C 0 53 113 0 46.90266 4 135 337 2.962963 40.05935 0.32 0.775 1 0031226 intrinsic to plasma membrane C 0 0 0 0 0 2 105 167 1.904762 62.87425 -0.421 0.775 1 0007155 cell adhesion P 1 79 132 1.265823 59.84848 2 116 252 1.724138 46.03175 -0.57 0.775 1 0015672 monovalent inorganic cation transport P 0 0 0 0 0 4 135 237 2.962963 56.96202 0.32 0.78 1 0005887 integral to plasma membrane C 1 37 50 2.702703 74 2 102 161 1.960784 63.35404 -0.378 0.781 1 0050877 neurophysiological process P 0 0 0 0 0 3 156 229 1.923077 68.12227 -0.503 0.783 1 0005506 iron ion binding F 2 106 190 1.886792 55.78947 2 111 211 1.801802 52.60664 -0.504 0.783 1 0051234 establishment of localization P 0 0 0 0 0 20 846 1824 2.364066 46.38158 -0.384 0.792 1 0030154 cell differentiation P 1 78 109 1.282051 71.55963 3 147 206 2.040816 71.35922 -0.394 0.799 1 0008104 protein localization P 0 1 5 0 20 5 166 358 3.012048 46.36871 0.398 0.803 1 0045184 establishment of protein localization P 0 0 0 0 0 5 165 352 3.030303 46.875 0.412 0.808 1 0003674 molecular_function F 0 0 0 0 0 72 2813 11011 2.559545 25.54718 0.268 0.81 1 0043167 ion binding F 0 0 0 0 0 18 749 1913 2.403204 39.15316 -0.275 0.812 1 0046872 metal ion binding F 7 311 568 2.250804 54.75352 18 749 1913 2.403204 39.15316 -0.275 0.812 1 0044237 cellular metabolism P 0 0 0 0 0 37 1400 4238 2.642857 33.03445 0.335 0.815 1 0004175 endopeptidase activity F 0 1 1 0 100 3 142 352 2.112676 40.34091 -0.332 0.817 1 0016021 integral to membrane C 24 971 2722 2.471679 35.6723 25 1040 2888 2.403846 36.01108 -0.346 0.817 1 0006629 lipid metabolism P 1 60 91 1.666667 65.93407 5 176 304 2.840909 57.89474 0.261 0.818 1 0005622 intracellular C 1 93 447 1.075269 20.80537 33 1349 3755 2.446256 35.92543 -0.296 0.818 1 0031224 intrinsic to membrane C 0 0 0 0 0 25 1043 2894 2.396932 36.04008 -0.364 0.821 1 0008270 zinc ion binding F 4 189 815 2.116402 23.19018 4 189 815 2.116402 23.19018 -0.382 0.828 1 0016740 transferase activity F 8 265 464 3.018868 57.11207 10 423 1100 2.364066 38.45454 -0.248 0.86 1 0000166 nucleotide binding F 8 367 686 2.179837 53.49854 11 459 1252 2.396514 36.66134 -0.212 0.875 1 0008152 metabolism P 4 107 312 3.738318 34.29487 39 1503 4617 2.59481 32.55361 0.191 0.913 1 0001775 cell activation P 0 0 0 0 0 1 20 27 5 74.07407 0.701 1 1 0045321 immune cell activation P 0 0 0 0 0 1 20 27 5 74.07407 0.701 1 1 0004702 receptor signaling protein serine/threonine kinase activity F 0 0 1 0 0 1 20 28 5 71.42857 0.701 1 1 0019955 cytokine binding F 0 1 2 0 50 1 20 35 5 57.14286 0.701 1 1 0045182 translation regulator activity F 0 0 1 0 0 1 20 59 5 33.8983 0.701 1 1 0042802 protein self binding F 0 6 9 0 66.66666 1 20 27 5 74.07407 0.701 1 1 0000904 cellular morphogenesis during differentiation P 0 0 0 0 0 1 20 27 5 74.07407 0.701 1 1 0016459 myosin C 1 20 39 5 51.28205 1 20 39 5 51.28205 0.701 1 1 0006916 anti-apoptosis P 1 19 21 5.263158 90.47619 1 21 25 4.761905 84 0.649 1 1 0006800 oxygen and reactive oxygen species metabolism P 0 2 2 0 100 1 21 39 4.761905 53.84615 0.649 1 1 0016835 carbon-oxygen lyase activity F 0 0 0 0 0 1 21 42 4.761905 50 0.649 1 1 0016779 nucleotidyltransferase activity F 1 3 14 33.33333 21.42857 1 21 76 4.761905 27.63158 0.649 1 1 0006817 phosphate transport P 1 22 62 4.545455 35.48387 1 22 62 4.545455 35.48387 0.6 1 1 0004725 protein tyrosine phosphatase activity F 0 19 42 0 45.23809 1 22 46 4.545455 47.82609 0.6 1 1 0008168 methyltransferase activity F 0 5 22 0 22.72727 1 22 93 4.545455 23.65591 0.6 1 1 0048037 cofactor binding F 0 1 2 0 50 1 22 80 4.545455 27.5 0.6 1 1 0009968 negative regulation of signal transduction P 0 12 18 0 66.66666 1 22 32 4.545455 68.75 0.6 1 1 0006633 fatty acid biosynthesis P 1 18 24 5.555555 75 1 22 30 4.545455 73.33334 0.6 1 1 0046394 carboxylic acid biosynthesis P 0 0 0 0 0 1 23 31 4.347826 74.19355 0.553 1 1 0006865 amino acid transport P 1 20 39 5 51.28205 1 23 44 4.347826 52.27273 0.553 1 1 0016053 organic acid biosynthesis P 0 0 0 0 0 1 23 31 4.347826 74.19355 0.553 1 1 0019838 growth factor binding F 0 2 2 0 100 1 24 30 4.166667 80 0.508 1 1 0016741 transferase activity\, transferring one-carbon groups F 0 0 0 0 0 1 24 97 4.166667 24.74227 0.508 1 1 0006935 chemotaxis P 1 19 22 5.263158 86.36364 1 24 28 4.166667 85.71429 0.508 1 1 0044271 nitrogen compound biosynthesis P 0 0 0 0 0 1 24 44 4.166667 54.54546 0.508 1 1 0050878 regulation of body fluids P 0 1 1 0 100 1 24 39 4.166667 61.53846 0.508 1 1 0045786 negative regulation of progression through cell cycle P 0 13 20 0 65 1 24 38 4.166667 63.15789 0.508 1 1 0042330 taxis P 0 0 0 0 0 1 24 28 4.166667 85.71429 0.508 1 1 0005096 GTPase activator activity F 1 22 35 4.545455 62.85714 1 24 44 4.166667 54.54546 0.508 1 1 0009309 amine biosynthesis P 0 0 0 0 0 1 24 44 4.166667 54.54546 0.508 1 1 0015203 polyamine transporter activity F 0 0 0 0 0 1 24 43 4.166667 55.81395 0.508 1 1 0005279 amino acid-polyamine transporter activity F 1 14 31 7.142857 45.16129 1 24 43 4.166667 55.81395 0.508 1 1 0043066 negative regulation of apoptosis P 0 4 6 0 66.66666 1 25 31 4 80.64516 0.466 1 1 0008076 voltage-gated potassium channel complex C 1 25 48 4 52.08333 1 25 48 4 52.08333 0.466 1 1 0007283 spermatogenesis P 1 22 33 4.545455 66.66666 1 25 38 4 65.78947 0.466 1 1 0048232 male gamete generation P 0 0 0 0 0 1 25 38 4 65.78947 0.466 1 1 0019904 protein domain specific binding F 0 15 19 0 78.94736 1 25 33 4 75.75758 0.466 1 1 0016712 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced flavin or flavoprotein as one donor\, and incorporation of one atom of oxygen F 1 7 15 14.28571 46.66667 1 25 41 4 60.97561 0.466 1 1 0042445 hormone metabolism P 0 1 1 0 100 1 26 30 3.846154 86.66666 0.425 1 1 0007269 neurotransmitter secretion P 0 7 10 0 70 1 26 31 3.846154 83.87096 0.425 1 1 0019842 vitamin binding F 0 2 2 0 100 1 26 47 3.846154 55.31915 0.425 1 1 0004867 serine-type endopeptidase inhibitor activity F 0 25 73 0 34.24657 1 26 74 3.846154 35.13514 0.425 1 1 0045055 regulated secretory pathway P 0 0 0 0 0 1 26 31 3.846154 83.87096 0.425 1 1 0043069 negative regulation of programmed cell death P 0 1 1 0 100 1 26 32 3.846154 81.25 0.425 1 1 0005083 small GTPase regulator activity F 0 2 8 0 25 1 26 76 3.846154 34.21053 0.425 1 1 0009108 coenzyme biosynthesis P 0 0 1 0 0 1 27 75 3.703704 36 0.386 1 1 0006643 membrane lipid metabolism P 0 0 0 0 0 1 27 48 3.703704 56.25 0.386 1 1 0015837 amine transport P 0 0 0 0 0 1 27 49 3.703704 55.10204 0.386 1 1 0031324 negative regulation of cellular metabolism P 0 0 0 0 0 1 27 46 3.703704 58.69565 0.386 1 1 0005941 unlocalized protein complex C 0 0 0 0 0 1 27 48 3.703704 56.25 0.386 1 1 0007276 gametogenesis P 0 0 7 0 0 1 27 47 3.703704 57.44681 0.386 1 1 0004252 serine-type endopeptidase activity F 0 4 5 0 80 2 61 151 3.278688 40.39735 0.37 1 1 0003723 RNA binding F 2 49 181 4.081633 27.07182 2 61 216 3.278688 28.24074 0.37 1 1 0040011 locomotion P 0 0 0 0 0 1 28 41 3.571429 68.29269 0.348 1 1 0051674 localization of cell P 0 0 0 0 0 1 28 41 3.571429 68.29269 0.348 1 1 0004879 ligand-dependent nuclear receptor activity F 0 1 3 0 33.33333 1 28 41 3.571429 68.29269 0.348 1 1 0004197 cysteine-type endopeptidase activity F 0 9 58 0 15.51724 1 28 91 3.571429 30.76923 0.348 1 1 0003707 steroid hormone receptor activity F 1 25 36 4 69.44444 1 28 40 3.571429 70 0.348 1 1 0006928 cell motility P 1 6 8 16.66667 75 1 28 41 3.571429 68.29269 0.348 1 1 0030955 potassium ion binding F 2 62 71 3.225806 87.32394 2 62 71 3.225806 87.32394 0.347 1 1 0016829 lyase activity F 2 40 52 5 76.92308 2 62 111 3.225806 55.85585 0.347 1 1 0031420 alkali metal ion binding F 0 0 0 0 0 2 62 71 3.225806 87.32394 0.347 1 1 0005743 mitochondrial inner membrane C 1 13 37 7.692307 35.13514 1 29 63 3.448276 46.03175 0.312 1 1 0051188 cofactor biosynthesis P 0 0 0 0 0 1 29 82 3.448276 35.36585 0.312 1 1 0016810 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds F 0 2 4 0 50 1 29 58 3.448276 50 0.312 1 1 0015171 amino acid transporter activity F 0 3 3 0 100 1 29 50 3.448276 58 0.312 1 1 0005975 carbohydrate metabolism P 0 47 123 0 38.21138 3 101 258 2.970297 39.14729 0.279 1 1 0008236 serine-type peptidase activity F 0 3 8 0 37.5 2 65 164 3.076923 39.63415 0.278 1 1 0016853 isomerase activity F 1 24 44 4.166667 54.54546 1 30 74 3.333333 40.54054 0.277 1 1 0006631 fatty acid metabolism P 1 29 36 3.448276 80.55556 2 66 87 3.030303 75.86207 0.256 1 1 0005525 GTP binding F 3 103 237 2.912621 43.45992 3 103 237 2.912621 43.45992 0.244 1 1 0042060 wound healing P 0 5 6 0 83.33334 1 31 45 3.225806 68.88889 0.244 1 1 0008234 cysteine-type peptidase activity F 0 11 18 0 61.11111 1 31 105 3.225806 29.52381 0.244 1 1 0017111 nucleoside-triphosphatase activity F 1 12 51 8.333333 23.52941 3 104 295 2.884615 35.25424 0.227 1 1 0009605 response to external stimulus P 0 1 1 0 100 4 142 200 2.816901 71 0.215 1 1 0006694 steroid biosynthesis P 0 6 12 0 50 1 32 42 3.125 76.19048 0.211 1 1 0015849 organic acid transport P 0 0 0 0 0 1 32 57 3.125 56.14035 0.211 1 1 0046942 carboxylic acid transport P 0 0 0 0 0 1 32 57 3.125 56.14035 0.211 1 1 0009892 negative regulation of metabolism P 0 1 1 0 100 1 32 58 3.125 55.17241 0.211 1 1 0005509 calcium ion binding F 7 256 538 2.734375 47.58364 7 256 538 2.734375 47.58364 0.207 1 1 0019001 guanyl nucleotide binding F 0 1 1 0 100 3 106 240 2.830189 44.16667 0.193 1 1 0042625 ATPase activity\, coupled to transmembrane movement of ions F 0 1 1 0 100 1 33 75 3.030303 44 0.18 1 1 0007610 behavior P 0 0 0 0 0 2 70 88 2.857143 79.54546 0.171 1 1 0016462 pyrophosphatase activity F 0 0 1 0 0 3 108 309 2.777778 34.95146 0.16 1 1 0043068 positive regulation of programmed cell death P 0 0 0 0 0 1 34 42 2.941176 80.95238 0.149 1 1 0007218 neuropeptide signaling pathway P 1 34 49 2.941176 69.38776 1 34 49 2.941176 69.38776 0.149 1 1 0005489 electron transporter activity F 0 21 77 0 27.27273 1 34 113 2.941176 30.0885 0.149 1 1 0043065 positive regulation of apoptosis P 1 10 12 10 83.33334 1 34 42 2.941176 80.95238 0.149 1 1 0006897 endocytosis P 1 22 29 4.545455 75.86207 1 34 44 2.941176 77.27273 0.149 1 1 0005275 amine transporter activity F 0 1 1 0 100 1 34 58 2.941176 58.62069 0.149 1 1 0050874 organismal physiological process P 0 1 1 0 100 10 377 604 2.65252 62.41722 0.148 1 1 0016818 hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides F 0 0 1 0 0 3 109 313 2.752294 34.82428 0.143 1 1 0007600 sensory perception P 2 58 78 3.448276 74.35897 2 72 125 2.777778 57.6 0.13 1 1 0009966 regulation of signal transduction P 0 1 8 0 12.5 1 35 57 2.857143 61.40351 0.12 1 1 0046983 protein dimerization activity F 0 9 20 0 45 1 35 58 2.857143 60.34483 0.12 1 1 0009888 tissue development P 0 2 2 0 100 1 35 45 2.857143 77.77778 0.12 1 1 0016817 hydrolase activity\, acting on acid anhydrides F 0 0 0 0 0 3 111 316 2.702703 35.12658 0.111 1 1 0005179 hormone activity F 2 67 93 2.985075 72.04301 2 73 103 2.739726 70.87379 0.11 1 1 0005057 receptor signaling protein activity F 1 7 7 14.28571 100 1 36 49 2.777778 73.46939 0.091 1 1 0000323 lytic vacuole C 0 0 2 0 0 1 36 46 2.777778 78.26087 0.091 1 1 0005764 lysosome C 1 30 37 3.333333 81.08108 1 36 44 2.777778 81.81818 0.091 1 1 0005342 organic acid transporter activity F 0 0 0 0 0 1 36 66 2.777778 54.54546 0.091 1 1 0048468 cell development P 0 1 1 0 100 1 36 46 2.777778 78.26087 0.091 1 1 0006470 protein amino acid dephosphorylation P 1 36 86 2.777778 41.86047 1 36 86 2.777778 41.86047 0.091 1 1 0001505 regulation of neurotransmitter levels P 0 1 1 0 100 1 36 47 2.777778 76.59574 0.091 1 1 0005773 vacuole C 0 0 1 0 0 1 36 48 2.777778 75 0.091 1 1 0046943 carboxylic acid transporter activity F 0 0 0 0 0 1 36 66 2.777778 54.54546 0.091 1 1 0009308 amine metabolism P 0 0 0 0 0 2 75 175 2.666667 42.85714 0.071 1 1 0005488 binding F 1 75 223 1.333333 33.63229 51 1997 5708 2.553831 34.98598 0.068 1 1 0006118 electron transport P 3 113 300 2.654867 37.66667 3 114 311 2.631579 36.65595 0.063 1 1 0019953 sexual reproduction P 0 2 4 0 50 1 37 64 2.702703 57.8125 0.063 1 1 0015629 actin cytoskeleton C 0 6 11 0 54.54546 1 37 73 2.702703 50.68493 0.063 1 1 0008047 enzyme activator activity F 0 4 7 0 57.14286 1 37 61 2.702703 60.65574 0.063 1 1 0019725 cell homeostasis P 0 0 0 0 0 1 37 62 2.702703 59.67742 0.063 1 1 0043231 intracellular membrane-bound organelle C 0 0 1 0 0 26 1014 2426 2.564103 41.7972 0.06 1 1 0043227 membrane-bound organelle C 0 0 0 0 0 26 1014 2426 2.564103 41.7972 0.06 1 1 0006915 apoptosis P 0 50 82 0 60.97561 3 116 173 2.586207 67.05202 0.032 1 1 0005576 extracellular region C 4 138 280 2.898551 49.28571 9 352 613 2.556818 57.42251 0.021 1 1 0012501 programmed cell death P 0 0 0 0 0 3 117 174 2.564103 67.24138 0.017 1 1 0030182 neuron differentiation P 1 9 11 11.11111 81.81818 1 39 53 2.564103 73.58491 0.01 1 1 0015405 P-P-bond-hydrolysis-driven transporter activity F 0 0 0 0 0 1 39 90 2.564103 43.33333 0.01 1 1 GO Gene Ontology r 0 0 0 0 0 76 2992 11884 2.540107 25.17671 0 1 1 0009887 organ morphogenesis P 0 0 1 0 0 1 40 53 2.5 75.47169 -0.016 1 1 0015293 symporter activity F 1 35 44 2.857143 79.54546 1 40 59 2.5 67.79661 -0.016 1 1 0004263 chymotrypsin activity F 1 40 119 2.5 33.61345 1 40 119 2.5 33.61345 -0.016 1 1 0006807 nitrogen compound metabolism P 0 2 7 0 28.57143 2 82 187 2.439024 43.85027 -0.059 1 1 0015031 protein transport P 2 67 127 2.985075 52.75591 4 162 348 2.469136 46.55172 -0.059 1 1 0008219 cell death P 0 3 4 0 75 3 124 186 2.419355 66.66666 -0.087 1 1 0019866 inner membrane C 0 18 26 0 69.23077 1 43 79 2.325581 54.43038 -0.09 1 1 0004295 trypsin activity F 1 41 126 2.439024 32.53968 1 43 128 2.325581 33.59375 -0.09 1 1 0006813 potassium ion transport P 2 84 126 2.380952 66.66666 2 84 126 2.380952 66.66666 -0.094 1 1 0016265 death P 0 0 0 0 0 3 125 187 2.4 66.84492 -0.102 1 1 0015290 electrochemical potential-driven transporter activity F 0 0 0 0 0 2 85 156 2.352941 54.48718 -0.111 1 1 0015291 porter activity F 0 0 0 0 0 2 85 156 2.352941 54.48718 -0.111 1 1 0006887 exocytosis P 0 16 21 0 76.19048 1 44 55 2.272727 80 -0.114 1 1 0043169 cation binding F 0 0 0 0 0 15 606 1666 2.475248 36.37455 -0.114 1 1 0030695 GTPase regulator activity F 0 0 0 0 0 1 45 106 2.222222 42.45283 -0.137 1 1 0004497 monooxygenase activity F 0 24 58 0 41.37931 1 45 93 2.222222 48.3871 -0.137 1 1 0030001 metal ion transport P 0 8 21 0 38.09524 4 169 277 2.366864 61.01083 -0.147 1 1 0004721 phosphoprotein phosphatase activity F 0 13 18 0 72.22222 1 46 98 2.173913 46.93877 -0.159 1 1 0008202 steroid metabolism P 0 15 28 0 53.57143 1 46 70 2.173913 65.71429 -0.159 1 1 0007626 locomotory behavior P 0 3 4 0 75 1 46 63 2.173913 73.01588 -0.159 1 1 0050080 malonyl-CoA decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004402 histone acetyltransferase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0047298 (S)-3-amino-2-methylpropionate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008616 queuosine biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004418 hydroxymethylbilane synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005141 interleukin-10 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009448 gamma-aminobutyric acid metabolism P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004056 argininosuccinate lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004839 ubiquitin activating enzyme activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0030346 protein phosphatase 2B binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042092 T-helper 2 type immune response P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003878 ATP citrate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003912 DNA nucleotidylexotransferase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0003890 beta DNA polymerase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0042608 T cell receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045347 negative regulation of MHC class II biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048010 vascular endothelial growth factor receptor signaling pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005786 signal recognition particle (sensu Eukaryota) C 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.161 1 1 0042100 B cell proliferation P 0 1 2 0 50 0 1 3 0 33.33333 -0.161 1 1 0004137 deoxycytidine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008479 queuine tRNA-ribosyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005989 lactose biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004461 lactose synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045191 regulation of isotype switching P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008534 purine-specific oxidized base lesion DNA N-glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042130 negative regulation of T cell proliferation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045019 negative regulation of nitric oxide biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005497 androgen binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004882 androgen receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006614 SRP-dependent cotranslational protein targeting to membrane P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0015868 purine ribonucleotide transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004649 poly(ADP-ribose) glycohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008434 vitamin D3 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008097 5S rRNA binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006290 pyrimidine dimer repair P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015780 nucleotide-sugar transport P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0006303 double-strand break repair via nonhomologous end-joining P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005338 nucleotide-sugar transporter activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0016211 ammonia ligase activity F 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0007130 synaptonemal complex formation P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004003 ATP-dependent DNA helicase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0001590 dopamine D1 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042755 eating behavior P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004645 phosphorylase activity F 0 1 1 0 100 0 1 3 0 33.33333 -0.161 1 1 0003985 acetyl-CoA C-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004128 cytochrome-b5 reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004294 tripeptidyl-peptidase II activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019003 GDP binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003804 coagulation factor Xa activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009288 flagellum (sensu Bacteria) C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0045687 positive regulation of glial cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003867 4-aminobutyrate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004449 isocitrate dehydrogenase (NAD+) activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0046790 virion binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0000175 3’-5’-exoribonuclease activity F 0 1 8 0 12.5 0 1 8 0 12.5 -0.161 1 1 0008117 sphinganine-1-phosphate aldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000067 DNA replication and chromosome cycle P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0018107 peptidyl-threonine phosphorylation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008628 induction of apoptosis by hormones P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008470 isovaleryl-CoA dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000137 Golgi cis cisterna C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030277 maintenance of gastrointestinal epithelium P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016572 histone phosphorylation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005315 inorganic phosphate transporter activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0001556 oocyte maturation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004397 histidine ammonia-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030502 negative regulation of bone mineralization P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050930 induction of positive chemotaxis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004157 dihydropyrimidinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048406 nerve growth factor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045907 positive regulation of vasoconstriction P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005251 delayed rectifier potassium channel activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016142 O-glycoside catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004560 alpha-L-fucosidase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004509 steroid 21-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004021 alanine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001848 complement binding F 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0016183 synaptic vesicle coating P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001315 age-dependent response to reactive oxygen species P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003889 alpha DNA polymerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019770 IgG receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004940 beta1-adrenergic receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050916 sensory perception of sweet taste P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008441 3’(2’)\,5’-bisphosphate nucleotidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006510 ATP-dependent proteolysis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008398 sterol 14-demethylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004700 atypical protein kinase C activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042132 fructose-bisphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030235 nitric-oxide synthase regulator activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030911 TPR domain binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006696 ergosterol biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004276 furin activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004322 ferroxidase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005658 alpha DNA polymerase\:primase complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005237 inhibitory extracellular ligand-gated ion channel activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016532 superoxide dismutase copper chaperone activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004693 cyclin-dependent protein kinase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0005097 Rab GTPase activator activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004240 mitochondrial processing peptidase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006627 mitochondrial protein processing P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045095 keratin filament C 0 1 9 0 11.11111 0 1 9 0 11.11111 -0.161 1 1 0009898 internal side of plasma membrane C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004655 porphobilinogen synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005869 dynactin complex C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006004 fucose metabolism P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004692 cGMP-dependent protein kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004085 butyryl-CoA dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004883 glucocorticoid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004776 succinate-CoA ligase (GDP-forming) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008095 inositol-1\,4\,5-triphosphate receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030174 regulation of DNA replication initiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004008 copper-exporting ATPase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004884 ecdysteroid hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007632 visual behavior P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030913 paranodal junction formation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050917 sensory perception of umami taste P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0019221 cytokine and chemokine mediated signaling pathway P 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.161 1 1 0030856 regulation of epithelial cell differentiation P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005290 L-histidine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006868 L-glutamine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015182 L-asparagine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006867 L-asparagine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015186 L-glutamine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004986 delta-opioid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048143 astrocyte activation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048151 hyperphosphorylation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045917 positive regulation of complement activation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009045 xylose isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006086 acetyl-CoA biosynthesis from pyruvate P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006685 sphingomyelin catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001639 PLC activating metabotropic glutamate receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048170 positive regulation of long-term neuronal synaptic plasticity P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007206 metabotropic glutamate receptor\, phospholipase C activating pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030126 COPI vesicle coat C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005330 dopamine\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004347 glucose-6-phosphate isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015035 protein disulfide oxidoreductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004941 beta2-adrenergic receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015844 monoamine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030971 receptor tyrosine kinase binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004743 pyruvate kinase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0030071 regulation of mitotic metaphase/anaphase transition P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004794 threonine ammonia-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005674 transcription factor TFIIF complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000212 meiotic spindle organization and biogenesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000930 gamma-tubulin complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005827 polar microtubule C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007020 microtubule nucleation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016986 transcription initiation factor activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0015382 sodium\:sulfate symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050780 dopamine receptor binding F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0004988 mu-opioid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015817 L-histidine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003834 beta-carotene 15\,15’-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008907 integrase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005680 anaphase-promoting complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045603 positive regulation of endothelial cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048227 plasma membrane to endosome transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005055 laminin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003978 UDP-glucose 4-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004833 tryptophan 2\,3-dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005026 transforming growth factor beta receptor activity\, type II F 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0050353 trimethyllysine dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001675 acrosome formation P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004445 inositol-polyphosphate 5-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004687 myosin light chain kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004146 dihydrofolate reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003705 RNA polymerase II transcription factor activity\, enhancer binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016519 gastric inhibitory peptide receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006177 GMP biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003938 IMP dehydrogenase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006569 tryptophan catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030429 kynureninase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009408 response to heat P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0001612 A2B adenosine receptor activity\, G-protein coupled F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045502 dynein binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005183 luteinizing hormone-releasing factor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003920 GMP reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043105 negative regulation of GTP cyclohydrolase I activity P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006545 glycine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008462 endopeptidase Clp activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001676 long-chain fatty acid metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0010142 farnesyl diphosphate biosynthesis\, mevalonate pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030432 peristalsis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047522 15-oxoprostaglandin 13-oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004530 deoxyribonuclease I activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005138 interleukin-6 receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004096 catalase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030250 guanylate cyclase activator activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0018024 histone-lysine N-methyltransferase activity F 0 1 5 0 20 0 1 5 0 20 -0.161 1 1 0046826 negative regulation of protein export from nucleus P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019853 L-ascorbic acid biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003885 D-arabinono-1\,4-lactone oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050105 L-gulonolactone oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009062 fatty acid catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009758 carbohydrate utilization P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019910 pyruvate dehydrogenase (lipoamide) phosphatase complex (sensu Eukaryota) C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050995 negative regulation of lipid catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045416 positive regulation of interleukin-8 biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042119 neutrophil activation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050748 negative regulation of lipoprotein metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016206 catechol O-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030285 integral to synaptic vesicle membrane C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004283 plasmin activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001894 tissue homeostasis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045732 positive regulation of protein catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048006 antigen presentation\, endogenous lipid antigen P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016045 detection of bacteria P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045089 positive regulation of innate immune response P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004155 6\,7-dihydropteridine reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045668 negative regulation of osteoblast differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019735 antimicrobial humoral response (sensu Vertebrata) P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043106 GTP cyclohydrolase I binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004747 ribokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001509 legumain activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0042412 taurine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003721 telomeric template RNA reverse transcriptase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004122 cystathionine beta-synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019343 cysteine biosynthesis via cystathione P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006535 cysteine biosynthesis from serine P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007498 mesoderm development P 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0008543 fibroblast growth factor receptor signaling pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048260 positive regulation of receptor mediated endocytosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030326 embryonic limb morphogenesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0050677 positive regulation of urothelial cell proliferation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030728 ovulation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004782 sulfinoalanine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0030508 thiol-disulfide exchange intermediate activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019870 potassium channel inhibitor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0045794 negative regulation of cell volume P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042383 sarcolemma C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019369 arachidonic acid metabolism P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0042554 superoxide release P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004052 arachidonate 12-lipoxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047977 hepoxilin-epoxide hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004281 pancreatic elastase II activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007190 adenylate cyclase activation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045576 mast cell activation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0018279 protein amino acid N-linked glycosylation via asparagine P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006014 D-ribose metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046836 glycolipid transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004363 glutathione synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004452 isopentenyl-diphosphate delta-isomerase activity F 0 1 8 0 12.5 0 1 8 0 12.5 -0.161 1 1 0015373 monovalent anion\:sodium symporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0047499 calcium-independent phospholipase A2 activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015204 urea transporter activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0042282 hydroxymethylglutaryl-CoA reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004505 phenylalanine 4-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048244 phytanoyl-CoA dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008250 oligosaccharyl transferase complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001561 fatty acid alpha-oxidation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004946 bombesin receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system P 0 1 8 0 12.5 0 1 8 0 12.5 -0.161 1 1 0016339 calcium-dependent cell-cell adhesion P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016557 peroxisome membrane biogenesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005779 integral to peroxisomal membrane C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008531 riboflavin kinase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0009231 riboflavin biosynthesis P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008013 beta-catenin binding F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0003941 L-serine ammonia-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001616 growth hormone secretagogue receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030520 estrogen receptor signaling pathway P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005099 Ras GTPase activator activity F 0 1 5 0 20 0 1 5 0 20 -0.161 1 1 0046580 negative regulation of Ras protein signal transduction P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0004419 hydroxymethylglutaryl-CoA lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004686 eukaryotic elongation factor-2 kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017075 syntaxin-1 binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016936 galactoside binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003796 lysozyme activity F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.161 1 1 0016998 cell wall catabolism P 0 1 10 0 10 0 1 10 0 10 -0.161 1 1 0004506 squalene monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004992 platelet activating factor receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045955 negative regulation of calcium ion-dependent exocytosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043236 laminin binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005586 collagen type III C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016992 lipoate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030263 apoptotic chromosome condensation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003939 L-iditol 2-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016212 kynurenine-oxoglutarate transaminase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0047536 2-aminoadipate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004765 shikimate kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005577 fibrinogen complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050576 3-keto-steroid reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003830 beta-1\,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030128 clathrin coat of endocytic vesicle C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004551 nucleotide diphosphatase activity F 0 1 2 0 50 0 1 3 0 33.33333 -0.161 1 1 0050516 inositol polyphosphate multikinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004192 cathepsin D activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030284 estrogen receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0007405 neuroblast proliferation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006368 RNA elongation from RNA polymerase II promoter P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008502 melatonin receptor activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0000300 peripheral to membrane of membrane fraction C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046951 ketone body biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008269 JAK pathway signal transduction adaptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005173 stem cell factor receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007076 mitotic chromosome condensation P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0046085 adenosine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000739 DNA strand annealing activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004617 phosphoglycerate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006106 fumarate metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045239 tricarboxylic acid cycle enzyme complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004333 fumarate hydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017022 myosin binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005159 insulin-like growth factor receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003986 acetyl-CoA hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004666 prostaglandin-endoperoxide synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008489 UDP-galactose\:glucosylceramide beta-1\,4-galactosyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0017168 5-oxoprolinase (ATP-hydrolyzing) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008023 transcription elongation factor complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005797 Golgi medial cisterna C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004246 peptidyl-dipeptidase A activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005579 membrane attack complex C 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0004421 hydroxymethylglutaryl-CoA synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003851 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016005 phospholipase A2 activator activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004511 tyrosine 3-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016322 neuron remodeling P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005135 interleukin-3 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009051 pentose-phosphate shunt\, oxidative branch P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004616 phosphogluconate dehydrogenase (decarboxylating) activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008089 anterograde axon cargo transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006957 complement activation\, alternative pathway P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0001593 dopamine D4 receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042104 positive regulation of activated T cell proliferation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006529 asparagine biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004066 asparagine synthase (glutamine-hydrolyzing) activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0050666 regulation of homocysteine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047150 betaine-homocysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001613 A3 adenosine receptor activity\, G-protein coupled F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001642 group III metabotropic glutamate receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004320 oleoyl-[acyl-carrier protein] hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015008 respiratory chain complex III (sensu Eukaryota) C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008121 ubiquinol-cytochrome-c reductase activity F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.161 1 1 0005486 t-SNARE activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0030601 aminopeptidase B activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009897 external side of plasma membrane C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0009107 lipoate biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003874 6-pyruvoyltetrahydropterin synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016931 vasopressin activated calcium mobilizing receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006894 Golgi to secretory vesicle transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004040 amidase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0017064 fatty acid amide hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004943 C3a anaphylatoxin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030506 ankyrin binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0045340 mercury ion binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004115 cAMP-specific phosphodiesterase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0050681 androgen receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0017025 TATA-binding protein binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009113 purine base biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004044 amidophosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046539 histamine N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004238 meprin A activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004465 lipoprotein lipase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004237 membrane dipeptidase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008625 induction of apoptosis via death domain receptors P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045650 negative regulation of macrophage differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004195 renin activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008198 ferrous iron binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008253 5’-nucleotidase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005793 ER-Golgi intermediate compartment C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019005 SCF ubiquitin ligase complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003980 UDP-glucose\:glycoprotein glucosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004051 arachidonate 5-lipoxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004873 asialoglycoprotein receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008894 guanosine-5’-triphosphate\,3’-diphosphate diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005134 interleukin-2 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005852 eukaryotic translation initiation factor 3 complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005010 insulin-like growth factor receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003979 UDP-glucose 6-dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016539 intein-mediated protein splicing P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004305 ethanolamine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050766 positive regulation of phagocytosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042462 eye photoreceptor cell development P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042987 amyloid precursor protein catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007220 Notch receptor processing P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0051084 posttranslational protein folding P 0 1 2 0 50 0 1 6 0 16.66667 -0.161 1 1 0007224 smoothened signaling pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017090 meprin A complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005137 interleukin-5 receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006930 substrate-bound cell migration\, cell extension P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005895 interleukin-5 receptor complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008093 cytoskeletal adaptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045545 syndecan binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004353 glutamate dehydrogenase [NAD(P)+] activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004447 iodide peroxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004835 tubulin-tyrosine ligase activity F 0 1 8 0 12.5 0 1 8 0 12.5 -0.161 1 1 0004337 geranyltranstransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004161 dimethylallyltranstransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043185 vascular endothelial growth factor receptor 3 binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005660 delta-DNA polymerase cofactor complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030337 DNA polymerase processivity factor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004473 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006265 DNA topological change P 0 1 5 0 20 0 1 5 0 20 -0.161 1 1 0003917 DNA topoisomerase type I activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0008466 glycogenin glucosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050178 phenylpyruvate tautomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008464 gamma-glutamyl hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045086 positive regulation of interleukin-2 biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042289 MHC class II protein binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019919 peptidyl-arginine methylation\, to asymmetrical-dimethyl arginine P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004324 ferredoxin-NADP+ reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004248 stromelysin 1 activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003840 gamma-glutamyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008482 sulfite oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006927 transformed cell apoptosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0010008 endosome membrane C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030217 T cell differentiation P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0015039 NADPH-adrenodoxin reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006120 mitochondrial electron transport\, NADH to ubiquinone P 0 1 11 0 9.090909 0 1 11 0 9.090909 -0.161 1 1 0004055 argininosuccinate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004504 peptidylglycine monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006686 sphingomyelin biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047493 ceramide cholinephosphotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008160 protein tyrosine phosphatase activator activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043161 proteasomal ubiquitin-dependent protein catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042359 vitamin D metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008061 chitin binding F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0004216 cathepsin K activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008488 gamma-glutamyl carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017187 peptidyl-glutamic acid carboxylation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017114 wide-spectrum protease inhibitor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0050849 negative regulation of calcium-mediated signaling P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008525 phosphatidylcholine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045059 positive thymic T cell selection P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004996 thyroid-stimulating hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008038 neuron recognition P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008247 2-acetyl-1-alkylglycerophosphocholine esterase complex C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004284 acrosin activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007341 penetration of zona pellucida P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004193 cathepsin E activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017154 semaphorin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004001 adenosine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050891 body fluid osmoregulation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047372 acylglycerol lipase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000154 rRNA modification P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0008649 rRNA methyltransferase activity F 0 1 2 0 50 0 1 4 0 25 -0.161 1 1 0006608 snRNP protein import into nucleus P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030519 snoRNP binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050774 negative regulation of dendrite morphogenesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006353 transcription termination P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030191 Hsp70/Hsc70 protein inhibitor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048146 positive regulation of fibroblast proliferation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042055 neuron lineage restriction P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004064 arylesterase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0003868 4-hydroxyphenylpyruvate dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005549 odorant binding F 0 1 2 0 50 0 1 14 0 7.142857 -0.161 1 1 0005787 signal peptidase complex C 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0007199 G-protein signaling\, coupled to cGMP nucleotide second messenger P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005227 calcium activated cation channel activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042624 ATPase activity\, uncoupled F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000086 G2/M transition of mitotic cell cycle P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047598 7-dehydrocholesterol reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030496 midbody C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005751 respiratory chain complex IV (sensu Eukaryota) C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006422 aspartyl-tRNA aminoacylation P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0004815 aspartate-tRNA ligase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0017101 aminoacyl-tRNA synthetase multienzyme complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008113 protein-methionine-S-oxide reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004074 biliverdin reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004215 cathepsin H activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004185 serine carboxypeptidase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0003973 (S)-2-hydroxy-acid oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016274 protein-arginine N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006789 bilirubin conjugation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005171 hepatocyte growth factor receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046696 lipopolysaccharide receptor complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042975 peroxisome proliferator activated receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004170 dUTP diphosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046080 dUTP metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008111 alpha-methylacyl-CoA racemase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006851 mitochondrial calcium ion transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007162 negative regulation of cell adhesion P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045921 positive regulation of exocytosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008131 amine oxidase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005669 transcription factor TFIID complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008106 alcohol dehydrogenase (NADP+) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006855 multidrug transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009253 peptidoglycan catabolism P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0045104 intermediate filament cytoskeleton organization and biogenesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001610 A1 adenosine receptor activity\, G-protein coupled F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001662 behavioral fear response P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003872 6-phosphofructokinase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0004618 phosphoglycerate kinase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0017050 D-erythro-sphingosine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046521 sphingoid catabolism P 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0001527 microfibril C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004286 proprotein convertase 2 activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001611 A2A adenosine receptor activity\, G-protein coupled F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006543 glutamine catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006883 sodium ion homeostasis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005143 interleukin-12 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030116 glial cell line-derived neurotrophic factor receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015350 methotrexate transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003934 GTP cyclohydrolase I activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042605 peptide antigen binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004968 gonadotropin-releasing hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016019 peptidoglycan receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030731 guanidinoacetate N-methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004772 sterol O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005133 interferon-gamma receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005945 6-phosphofructokinase complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0046967 cytosol to ER transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008745 N-acetylmuramoyl-L-alanine amidase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0042301 phosphate binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006123 mitochondrial electron transport\, cytochrome c to oxygen P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003958 NADPH-hemoprotein reductase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004163 diphosphomevalonate decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047305 (R)-3-amino-2-methylpropionate-pyruvate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006196 AMP catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046980 tapasin binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001657 ureteric bud development P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050772 positive regulation of axonogenesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0046920 alpha(1\,3)-fucosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004014 adenosylmethionine decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006597 spermine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008295 spermidine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001599 endothelin-A receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042346 positive regulation of NF-kappaB import into nucleus P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016574 histone ubiquitination P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000209 protein polyubiquitination P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004218 cathepsin S activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047066 phospholipid-hydroperoxide glutathione peroxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003808 protein C (activated) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042426 choline catabolism P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0030010 establishment of cell polarity P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006283 transcription-coupled nucleotide-excision repair P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004090 carbonyl reductase (NADPH) activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005146 leukemia inhibitory factor receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004801 transaldolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050727 regulation of inflammatory response P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004047 aminomethyltransferase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0004602 glutathione peroxidase activity F 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.161 1 1 0006546 glycine catabolism P 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.161 1 1 0008130 neutrophil collagenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005371 tricarboxylate carrier activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005152 interleukin-1 receptor antagonist activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0048237 rough endoplasmic reticulum lumen C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045787 positive regulation of progression through cell cycle P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008480 sarcosine dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046168 glycerol-3-phosphate catabolism P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0043008 ATP-dependent protein binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030332 cyclin binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005585 collagen type II C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008630 DNA damage response\, signal transduction resulting in induction of apoptosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004310 farnesyl-diphosphate farnesyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004823 leucine-tRNA ligase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004367 glycerol-3-phosphate dehydrogenase (NAD+) activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0009980 glutamate carboxypeptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009331 glycerol-3-phosphate dehydrogenase complex C 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0008273 calcium\, potassium\:sodium antiporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000792 heterochromatin C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015840 urea transport P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0009414 response to water deprivation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017106 activin inhibitor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004108 citrate (Si)-synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004944 C5a anaphylatoxin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015889 cobalamin transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030303 stromelysin 2 activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004340 glucokinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030870 Mre11 complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008472 metallocarboxypeptidase D activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006429 leucyl-tRNA aminoacylation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004517 nitric-oxide synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0009049 aspartic-type signal peptidase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0030976 thiamin pyrophosphate binding F 0 1 5 0 20 0 1 5 0 20 -0.161 1 1 0004229 gelatinase B activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004214 dipeptidyl-peptidase I activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016601 Rac protein signal transduction P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004773 steryl-sulfatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043275 glutamate carboxypeptidase II activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016512 endothelin-converting enzyme 1 activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030412 formimidoyltetrahydrofolate cyclodeaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003998 acylphosphatase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0004083 bisphosphoglycerate phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004769 steroid delta-isomerase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003884 D-amino-acid oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005686 snRNP U2 C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004990 oxytocin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009348 ornithine carbamoyltransferase complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004585 ornithine carbamoyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016604 nuclear body C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015870 acetylcholine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001579 medium-chain fatty acid transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008458 carnitine O-octanoyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005144 interleukin-13 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008722 DNA helicase IV activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0007616 long-term memory P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048041 focal adhesion formation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007140 male meiosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045121 lipid raft C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045070 positive regulation of viral genome replication P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004334 fumarylacetoacetase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042538 hyperosmotic salinity response P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017045 adrenocorticotropin-releasing hormone activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030409 glutamate formimidoyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015054 gastrin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046935 phosphatidylinositol 3-kinase regulator activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050805 negative regulation of synaptic transmission P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006906 vesicle fusion P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019215 intermediate filament binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004846 urate oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030273 melanin-concentrating hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004235 matrilysin activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016486 peptide hormone processing P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006744 ubiquinone biosynthesis P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008934 inositol-1(or 4)-monophosphatase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0019547 arginine catabolism to ornithine P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004234 macrophage elastase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046087 cytidine metabolism P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0001602 pancreatic polypeptide receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004126 cytidine deaminase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0042564 NLS-dependent protein nuclear import complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004995 tachykinin receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0001502 cartilage condensation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015879 carnitine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015226 carnitine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005672 transcription factor TFIIA complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030492 hemoglobin binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008478 pyridoxal kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0046882 negative regulation of follicle-stimulating hormone secretion P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006145 purine base catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016234 inclusion body C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019310 myo-inositol catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050113 inositol oxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019808 polyamine binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006301 postreplication repair P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008503 benzodiazepine receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004031 aldehyde oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000184 mRNA catabolism\, nonsense-mediated decay P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005071 transmembrane receptor protein serine/threonine kinase signaling protein activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001880 Mullerian duct regression P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016527 brain-specific angiogenesis inhibitor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016554 cytidine to uridine editing P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009992 cellular osmoregulation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006540 glutamate decarboxylation to succinate P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005232 serotonin-activated cation-selective channel activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004416 hydroxyacylglutathione hydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042632 cholesterol homeostasis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050750 low-density lipoprotein receptor binding F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005139 interleukin-7 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030544 Hsp70 protein binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0035042 fertilization\, exchange of chromosomal proteins P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001673 male germ cell nucleus C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006342 chromatin silencing P 0 1 6 0 16.66667 0 1 6 0 16.66667 -0.161 1 1 0006338 chromatin remodeling P 0 1 1 0 100 0 1 6 0 16.66667 -0.161 1 1 0007290 spermatid nuclear elongation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006337 nucleosome disassembly P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003905 alkylbase DNA N-glycosylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045578 negative regulation of B cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030833 regulation of actin filament polymerization P 0 1 5 0 20 0 1 6 0 16.66667 -0.161 1 1 0004745 retinol dehydrogenase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0042904 9-cis-retinoic acid biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008147 structural constituent of bone F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008431 vitamin E binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004528 phosphodiesterase I activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0043015 gamma-tubulin binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015722 canalicular bile acid transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004802 transketolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007143 female meiosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0017015 regulation of transforming growth factor beta receptor signaling pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006706 steroid catabolism P 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0030539 male genitalia morphogenesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0018352 protein-pyridoxal-5-phosphate linkage P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004335 galactokinase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004523 ribonuclease H activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0007030 Golgi organization and biogenesis P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0004243 mitochondrial intermediate peptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005129 granulocyte macrophage colony-stimulating factor receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005088 Ras guanyl-nucleotide exchange factor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030742 GTP-dependent protein binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001539 ciliary or flagellar motility P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0045651 positive regulation of macrophage differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000145 exocyst C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0019807 aspartoacylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043171 peptide catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004231 insulysin activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008091 spectrin C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050708 regulation of protein secretion P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003945 N-acetyllactosamine synthase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0000731 DNA synthesis during DNA repair P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003953 NAD+ nucleosidase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004123 cystathionine gamma-lyase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003989 acetyl-CoA carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046835 carbohydrate phosphorylation P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003999 adenine phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006168 adenine salvage P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004997 thyrotropin-releasing hormone receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0042045 epithelial fluid transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000049 tRNA binding F 0 1 5 0 20 0 1 5 0 20 -0.161 1 1 0007098 centrosome cycle P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016220 RAL GDP-dissociation stimulator activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048013 ephrin receptor signaling pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004964 lutropin-choriogonadotropic hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016919 nardilysin activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006583 melanin biosynthesis from tyrosine P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004167 dopachrome isomerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003913 DNA photolyase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016608 growth hormone-releasing hormone activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016117 carotenoid biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0003992 acetylornithine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004587 ornithine-oxo-acid transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030354 melanin-concentrating hormone activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045056 transcytosis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000062 acyl-CoA binding F 0 1 10 0 10 0 1 10 0 10 -0.161 1 1 0005070 SH3/SH2 adaptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004569 glycoprotein endo-alpha-1\,2-mannosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007131 meiotic recombination P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004365 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity F 0 1 22 0 4.545455 0 1 22 0 4.545455 -0.161 1 1 0005093 Rab GDP-dissociation inhibitor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005003 ephrin receptor activity F 0 1 8 0 12.5 0 1 8 0 12.5 -0.161 1 1 0035256 metabotropic glutatmate receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047035 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007339 binding of sperm to zona pellucida P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0004058 aromatic-L-amino-acid decarboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004254 acylaminoacyl-peptidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004516 nicotinate phosphoribosyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0047280 nicotinamide phosphoribosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019510 S-adenosylhomocysteine catabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004013 adenosylhomocysteinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004903 growth hormone receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006288 base-excision repair\, DNA ligation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009404 toxin metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042428 serotonin metabolism P 0 1 1 0 100 0 1 3 0 33.33333 -0.161 1 1 0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050501 hyaluronan synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006999 nuclear pore organization and biogenesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001735 prenylcysteine oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004760 serine-pyruvate transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008301 DNA bending activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042421 norepinephrine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0018872 arsonoacetate metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008307 structural constituent of muscle F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0016559 peroxisome fission P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0030187 melatonin biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004059 aralkylamine N-acetyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015051 X-opioid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045899 positive regulation of transcriptional preinitiation complex formation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016566 specific transcriptional repressor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004500 dopamine beta-monooxygenase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0005528 FK506 binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001514 selenocysteine incorporation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003730 mRNA 3’-UTR binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004075 biotin carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046881 positive regulation of follicle-stimulating hormone secretion P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043153 entrainment of circadian clock by photoperiod P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0031071 cysteine desulfurase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030792 methylarsonite methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030791 arsenite methyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004450 isocitrate dehydrogenase (NADP+) activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006097 glyoxylate cycle P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004900 erythropoietin receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003835 beta-galactoside alpha-2\,6-sialyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016287 glycerone-phosphate O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030283 3(or 17)beta-hydroxysteroid dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042557 eukaryotic elongation factor-2 kinase activator activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004691 cAMP-dependent protein kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046326 positive regulation of glucose import P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046318 negative regulation of glucosylceramide biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016847 1-aminocyclopropane-1-carboxylate synthase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0004838 tyrosine transaminase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007192 serotonin receptor\, adenylate cyclase activating pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048145 regulation of fibroblast proliferation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050798 activated T cell proliferation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008242 omega peptidase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0051054 positive regulation of DNA metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0048663 neuron fate commitment P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046006 regulation of activated T cell proliferation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045076 regulation of interleukin-2 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042094 interleukin-2 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0001754 eye photoreceptor cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050764 regulation of phagocytosis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0031335 regulation of sulfur amino acid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0031058 positive regulation of histone modification P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009311 oligosaccharide metabolism P 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0031056 regulation of histone modification P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0001654 eye development P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046530 photoreceptor cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0048592 eye morphogenesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051427 hormone receptor binding F 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0042436 indole derivative catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042575 DNA polymerase complex C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015993 molecular hydrogen transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0035258 steroid hormone receptor binding F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046112 nucleobase biosynthesis P 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0001591 dopamine D2 receptor-like receptor activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005484 SNAP receptor activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046218 indolalkylamine catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005659 delta DNA polymerase complex C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006528 asparagine metabolism P 0 0 1 0 0 0 1 3 0 33.33333 -0.161 1 1 0016681 oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor F 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0046950 ketone body metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045285 ubiquinol-cytochrome-c reductase complex C 0 0 1 0 0 0 1 4 0 25 -0.161 1 1 0045275 respiratory chain complex III C 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0004312 fatty-acid synthase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004470 malic enzyme activity F 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0003916 DNA topoisomerase activity F 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0016297 acyl-[acyl-carrier protein] hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0001640 adenylate cyclase inhibiting metabotropic glutamate receptor activity F 0 0 1 0 0 0 1 4 0 25 -0.161 1 1 0042461 photoreceptor cell development P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016679 oxidoreductase activity\, acting on diphenols and related substances as donors F 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0030249 guanylate cyclase regulator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046880 regulation of follicle-stimulating hormone secretion P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0048736 appendage development P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0050675 regulation of urothelial cell proliferation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050674 urothelial cell proliferation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051048 negative regulation of secretion P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0019530 taurine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016279 protein-lysine N-methyltransferase activity F 0 0 0 0 0 0 1 5 0 20 -0.161 1 1 0019211 phosphatase activator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016278 lysine N-methyltransferase activity F 0 0 0 0 0 0 1 5 0 20 -0.161 1 1 0030192 Hsp70/Hsc70 protein regulator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016531 copper chaperone activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046498 S-adenosylhomocysteine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016530 metallochaperone activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004774 succinate-CoA ligase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0044273 sulfur compound catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0007043 intercellular junction assembly P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0045216 intercellular junction assembly and/or maintenance P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046888 negative regulation of hormone secretion P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0007617 mating behavior P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0042982 amyloid precursor protein metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006516 glycoprotein catabolism P 0 0 3 0 0 0 1 4 0 25 -0.161 1 1 0031312 extrinsic to organelle membrane C 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0019934 cGMP-mediated signaling P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0043021 ribonucleoprotein binding F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0030908 protein splicing P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0006929 substrate-bound cell migration P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035113 embryonic appendage morphogenesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0019098 reproductive behavior P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046884 follicle-stimulating hormone secretion P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0007618 mating P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0008173 RNA methyltransferase activity F 0 0 0 0 0 0 1 10 0 10 -0.161 1 1 0030190 chaperone inhibitor activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050869 negative regulation of B cell activation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045620 negative regulation of lymphocyte differentiation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045619 regulation of lymphocyte differentiation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045577 regulation of B cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016838 carbon-oxygen lyase activity\, acting on phosphates F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016639 oxidoreductase activity\, acting on the CH-NH2 group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005432 calcium\:sodium antiporter activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005335 serotonin\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015222 serotonin transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030977 taurine binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015734 taurine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016109 tetraterpenoid biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0005369 taurine\:sodium symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008329 pattern recognition receptor activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0003714 transcription corepressor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0051346 negative regulation of hydrolase activity P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015193 L-proline transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019321 pentose metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0007064 mitotic sister chromatid cohesion P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016888 endodeoxyribonuclease activity\, producing 5’-phosphomonoesters F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0043095 regulation of GTP cyclohydrolase I activity P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008280 cohesin core heterodimer C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008177 succinate dehydrogenase (ubiquinone) activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0035257 nuclear hormone receptor binding F 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0015326 cationic amino acid transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045667 regulation of osteoblast differentiation P 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0000295 adenine nucleotide transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009262 deoxyribonucleotide metabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0015317 phosphate\:hydrogen symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009415 response to water P 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0015245 fatty acid transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015855 pyrimidine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047429 nucleoside-triphosphate diphosphatase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006837 serotonin transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016116 carotenoid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0019730 antimicrobial humoral response P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016108 tetraterpenoid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0050758 regulation of thymidylate synthase biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008507 sodium\:iodide symporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042834 peptidoglycan binding F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015705 iodide transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015187 glycine transporter activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0015824 L-proline transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003823 antigen binding F 0 0 8 0 0 0 1 10 0 10 -0.161 1 1 0005350 pyrimidine transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005076 receptor signaling protein serine/threonine kinase signaling protein activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008761 UDP-N-acetylglucosamine 2-epimerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006047 UDP-N-acetylglucosamine metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046351 disaccharide biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009384 N-acylmannosamine kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006476 protein amino acid deacetylation P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0019605 butyrate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0003678 DNA helicase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0005801 Golgi cis-face C 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0030567 prothrombin activator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001588 dopamine D1 receptor-like receptor activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0019861 flagellum C 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0008268 receptor signaling protein tyrosine kinase signaling protein activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0001636 corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006555 methionine metabolism P 0 0 1 0 0 0 1 3 0 33.33333 -0.161 1 1 0046037 GMP metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0042084 5-methyltetrahydrofolate-dependent methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0000726 non-recombinational repair P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0006601 creatine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050879 organismal movement P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0048500 signal recognition particle C 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0007231 osmosensory signaling pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009612 response to mechanical stimulus P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006613 cotranslational protein targeting to membrane P 0 0 1 0 0 0 1 4 0 25 -0.161 1 1 0006473 protein amino acid acetylation P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0045779 negative regulation of bone resorption P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009103 lipopolysaccharide biosynthesis P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0019902 phosphatase binding F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005988 lactose metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015068 glycine amidinotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019903 protein phosphatase binding F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008426 protein kinase C inhibitor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0001573 ganglioside metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0047915 ganglioside galactosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005984 disaccharide metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0030259 lipid glycosylation P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016137 glycoside metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005031 tumor necrosis factor receptor activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0035112 genitalia morphogenesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016833 oxo-acid-lyase activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0050848 regulation of calcium-mediated signaling P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0018200 peptidyl-glutamic acid modification P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0018214 protein amino acid carboxylation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015142 tricarboxylic acid transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016891 endoribonuclease activity\, producing 5’-phosphomonoesters F 0 0 3 0 0 0 1 10 0 10 -0.161 1 1 0030041 actin filament polymerization P 0 0 1 0 0 0 1 7 0 14.28571 -0.161 1 1 0043241 protein complex disassembly P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0003720 telomerase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042727 riboflavin and derivative biosynthesis P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0018065 protein-cofactor linkage P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006105 succinate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006536 glutamate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0050840 extracellular matrix binding F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0006538 glutamate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0048259 regulation of receptor mediated endocytosis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0000098 sulfur amino acid catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045920 negative regulation of exocytosis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009105 lipoic acid biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0009648 photoperiodism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051123 transcriptional preinitiation complex formation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045898 regulation of transcriptional preinitiation complex formation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006771 riboflavin metabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0003727 single-stranded RNA binding F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051058 negative regulation of small GTPase mediated signal transduction P 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0035065 regulation of histone acetylation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0031461 cullin-RING ubiquitin ligase complex C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042415 norepinephrine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035238 vitamin A biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045061 thymic T cell selection P 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0000273 lipoic acid metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0005527 macrolide binding F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006451 translational readthrough P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009106 lipoate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0042905 9-cis-retinoic acid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042362 fat-soluble vitamin biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035108 limb morphogenesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0042726 riboflavin and derivative metabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0005035 death receptor activity F 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0016573 histone acetylation P 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0016635 oxidoreductase activity\, acting on the CH-CH group of donors\, quinone or related compound as acceptor F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046040 IMP metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0006188 IMP biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046470 phosphatidylcholine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016774 phosphotransferase activity\, carboxyl group as acceptor F 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0016219 GDP-dissociation stimulator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0031498 chromatin disassembly P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0003933 GTP cyclohydrolase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005368 taurine transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006582 melanin metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006600 creatine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042438 melanin biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030880 RNA polymerase complex C 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0043120 tumor necrosis factor binding F 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0016251 general RNA polymerase II transcription factor activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0051130 positive regulation of cell organization and biogenesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015067 amidinotransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016273 arginine N-methyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046852 positive regulation of bone remodeling P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009593 detection of chemical stimulus P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0007289 spermatid nuclear differentiation P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016458 gene silencing P 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0031507 heterochromatin formation P 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0045814 negative regulation of gene expression\, epigenetic P 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0043073 germ cell nucleus C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008653 lipopolysaccharide metabolism P 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0043486 histone exchange P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0043096 purine base salvage P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035039 male pronucleus formation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035041 sperm chromatin decondensation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0031023 microtubule organizing center organization and biogenesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051297 centrosome organization and biogenesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035247 peptidyl-arginine omega-N-methylation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035246 peptidyl-arginine N-methylation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035107 appendage morphogenesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046219 indolalkylamine biosynthesis P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0043044 ATP-dependent chromatin remodeling P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0000152 nuclear ubiquitin ligase complex C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016730 oxidoreductase activity\, acting on iron-sulfur proteins as donors F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005876 spindle microtubule C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009261 ribonucleotide catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008943 glyceraldehyde-3-phosphate dehydrogenase activity F 0 0 0 0 0 0 1 22 0 4.545455 -0.161 1 1 0009158 ribonucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005092 GDP-dissociation inhibitor activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0045337 farnesyl diphosphate biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030186 melatonin metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006081 aldehyde metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046030 inositol trisphosphate phosphatase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046487 glyoxylate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015174 basic amino acid transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030449 regulation of complement activation P 0 0 2 0 0 0 1 3 0 33.33333 -0.161 1 1 0030137 COPI-coated vesicle C 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016413 O-acetyltransferase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0005329 dopamine transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009125 nucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0007091 mitotic metaphase/anaphase transition P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0001565 phorbol ester receptor activity F 0 0 1 0 0 0 1 3 0 33.33333 -0.161 1 1 0045047 protein targeting to ER P 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0016140 O-glycoside metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015928 fucosidase activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016802 trialkylsulfonium hydrolase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042054 histone methyltransferase activity F 0 0 0 0 0 0 1 5 0 20 -0.161 1 1 0006266 DNA ligation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051103 DNA ligation during DNA repair P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016731 oxidoreductase activity\, acting on iron-sulfur proteins as donors\, NAD or NADP as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004697 protein kinase C activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0035036 sperm-egg recognition P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0006997 nuclear organization and biogenesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008204 ergosterol metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016657 oxidoreductase activity\, acting on NADH or NADPH\, nitrogenous group as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016724 oxidoreductase activity\, oxidizing metal ions\, oxygen as acceptor F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016722 oxidoreductase activity\, oxidizing metal ions F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046033 AMP metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008937 ferredoxin reductase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009154 purine ribonucleotide catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006901 vesicle coating P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046520 sphingoid biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0035254 glutamate receptor binding F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0018196 peptidyl-asparagine modification P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046324 regulation of glucose import P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006677 glycosylceramide metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0006678 glucosylceramide metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0043205 fibril C 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0008241 peptidyl-dipeptidase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009169 purine ribonucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008037 cell recognition P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006842 tricarboxylic acid transport P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046513 ceramide biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046476 glycosylceramide biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006679 glucosylceramide biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046317 regulation of glucosylceramide biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0031231 intrinsic to peroxisomal membrane C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0048285 organelle fission P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0042435 indole derivative biosynthesis P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0016139 glycoside catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051055 negative regulation of lipid biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006638 neutral lipid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016004 phospholipase activator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045017 glycerolipid biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045338 farnesyl diphosphate metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046460 neutral lipid biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046504 glycerol ether biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046339 diacylglycerol metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006639 acylglycerol metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046323 glucose import P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006662 glycerol ether metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046463 acylglycerol biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046486 glycerolipid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016783 sulfurtransferase activity F 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0042556 eukaryotic elongation factor-2 kinase regulator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0019209 kinase activator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030295 protein kinase activator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0017002 activin receptor activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0015746 citrate transport P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009128 purine nucleoside monophosphate catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006195 purine nucleotide catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009055 electron carrier activity F 0 1 4 0 25 0 1 5 0 20 -0.161 1 1 0005753 proton-transporting ATP synthase complex (sensu Eukaryota) C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004156 dihydropteroate synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015865 purine nucleotide transport P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009396 folic acid and derivative biosynthesis P 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0007129 synapsis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0009086 methionine biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006110 regulation of glycolysis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003873 6-phosphofructo-2-kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008705 methionine synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004730 pseudouridylate synthase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0003937 IMP cyclohydrolase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050785 advanced glycation end-product receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003827 alpha-1\,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008455 alpha-1\,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009312 oligosaccharide biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030144 alpha-1\,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030048 actin filament-based movement P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0050760 negative regulation of thymidylate synthase biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048524 positive regulation of viral life cycle P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005850 eukaryotic translation initiation factor 2 complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009982 pseudouridine synthase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0050927 positive regulation of positive chemotaxis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0043121 neurotrophin binding F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045685 regulation of glial cell differentiation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030279 negative regulation of ossification P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0000334 3-hydroxyanthranilate 3\,4-dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046314 phosphocreatine biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0042406 extrinsic to endoplasmic reticulum membrane C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0050920 regulation of chemotaxis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050921 positive regulation of chemotaxis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015216 purine nucleotide transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050926 regulation of positive chemotaxis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0051341 regulation of oxidoreductase activity P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003708 retinoic acid receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016453 C-acetyltransferase activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0019131 tripeptidyl-peptidase I activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0035081 induction of programmed cell death by hormones P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0003858 3-hydroxybutyrate dehydrogenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004468 lysine N-acetyltransferase activity F 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006862 nucleotide transport P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050918 positive chemotaxis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004507 steroid 11-beta-monooxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0045749 negative regulation of S phase of mitotic cell cycle P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045153 electron transporter\, transferring electrons within CoQH2-cytochrome c reductase complex activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009804 coumarin metabolism P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008386 cholesterol monooxygenase (side-chain-cleaving) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004508 steroid 17-alpha-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008402 aromatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0018685 alkane 1-monooxygenase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008123 cholesterol 7-alpha-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050999 regulation of nitric-oxide synthase activity P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047783 corticosterone 18-monooxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004385 guanylate kinase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0043197 dendritic spine C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048531 beta-1\,3-galactosyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030228 lipoprotein receptor activity F 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0035014 phosphoinositide 3-kinase regulator activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004300 enoyl-CoA hydratase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004694 eukaryotic translation initiation factor 2alpha kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045993 negative regulation of translational initiation by iron P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046986 negative regulation of hemoglobin biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006699 bile acid biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008459 chondroitin 6-sulfotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043190 ATP-binding cassette (ABC) transporter complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008282 ATP-sensitive potassium channel complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008281 sulfonylurea receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0015646 permease activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005796 Golgi lumen C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0008336 gamma-butyrobetaine dioxygenase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019307 mannose biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0050998 nitric-oxide synthase binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008290 F-actin capping protein complex C 0 1 5 0 20 0 1 5 0 20 -0.161 1 1 0007620 copulation P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0017048 Rho GTPase binding F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0045671 negative regulation of osteoclast differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006661 phosphatidylinositol biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0009200 deoxyribonucleoside triphosphate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0042416 dopamine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0035094 response to nicotine P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0035005 phosphatidylinositol-4-phosphate 3-kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005602 complement component C1q complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008180 signalosome complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0004615 phosphomannomutase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0004978 adrenocorticotropin receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005140 interleukin-9 receptor binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015851 nucleobase transport P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045762 positive regulation of adenylate cyclase activity P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045190 isotype switching P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045342 MHC class II biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050431 transforming growth factor beta binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045346 regulation of MHC class II biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004938 alpha2-adrenergic receptor activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0051349 positive regulation of lyase activity P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004566 beta-glucuronidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004575 sucrose alpha-glucosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004829 threonine-tRNA ligase activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0006435 threonyl-tRNA aminoacylation P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0019136 deoxynucleoside kinase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008125 pancreatic elastase I activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000702 oxidized base lesion DNA N-glycosylase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004682 protein kinase CK2 activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006264 mitochondrial DNA replication P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006390 transcription from mitochondrial promoter P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016671 oxidoreductase activity\, acting on sulfur group of donors\, disulfide as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050868 negative regulation of T cell activation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050994 regulation of lipid catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006651 diacylglycerol biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009896 positive regulation of catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006611 protein export from nucleus P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015205 nucleobase transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046825 regulation of protein export from nucleus P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0050746 regulation of lipoprotein metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0042228 interleukin-8 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045414 regulation of interleukin-8 biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004574 oligo-1\,6-glucosidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0050649 testosterone 6-beta-hydroxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048003 antigen presentation\, lipid antigen P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009895 negative regulation of catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045253 pyruvate dehydrogenase (lipoamide) phosphatase complex C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016054 organic acid catabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046395 carboxylic acid catabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0001621 platelet ADP receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0048179 activin receptor complex C 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016361 activin receptor activity\, type I F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003807 plasma kallikrein activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0031281 positive regulation of cyclase activity P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005353 fructose transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009595 detection of biotic stimulus P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046116 queuosine metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0008143 poly(A) binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045598 regulation of fat cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006400 tRNA modification P 0 0 1 0 0 0 1 3 0 33.33333 -0.161 1 1 0006447 regulation of translational initiation by iron P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0003952 NAD+ synthase (glutamine-hydrolyzing) activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005760 gamma DNA polymerase complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019546 arginine deiminase pathway P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042455 ribonucleoside biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0008617 guanosine metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0009163 nucleoside biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016402 pristanoyl-CoA oxidase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042451 purine nucleoside biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0047498 calcium-dependent phospholipase A2 activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046129 purine ribonucleoside biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046114 guanosine biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0046118 7-methylguanosine biosynthesis P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016842 amidine-lyase activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0003895 gamma DNA-directed DNA polymerase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015137 citrate transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045777 positive regulation of blood pressure P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0000774 adenyl-nucleotide exchange factor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004478 methionine adenosyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046984 regulation of hemoglobin biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004346 glucose-6-phosphatase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015295 solute\:hydrogen symporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006895 Golgi to endosome transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016880 acid-ammonia (or amide) ligase activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0048477 oogenesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008618 7-methylguanosine metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0009994 oocyte differentiation P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015101 organic cation transporter activity F 0 1 1 0 100 0 1 2 0 50 -0.161 1 1 0004658 propionyl-CoA carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007281 germ cell development P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0048599 oocyte development P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0018210 peptidyl-threonine modification P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0015215 nucleotide transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016796 exonuclease activity\, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 0 1 8 0 12.5 -0.161 1 1 0004532 exoribonuclease activity F 0 0 0 0 0 0 1 8 0 12.5 -0.161 1 1 0016896 exoribonuclease activity\, producing 5’-phosphomonoesters F 0 0 0 0 0 0 1 8 0 12.5 -0.161 1 1 0051087 chaperone binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006843 mitochondrial citrate transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0051184 cofactor transporter activity F 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0019751 polyol metabolism P 0 0 0 0 0 0 1 10 0 10 -0.161 1 1 0004430 1-phosphatidylinositol 4-kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0047291 lactosylceramide alpha-2\,3-sialyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008118 N-acetyllactosaminide alpha-2\,3-sialyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030517 negative regulation of axon extension P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0005545 phosphatidylinositol binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001574 ganglioside biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016511 endothelin-converting enzyme activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005314 high-affinity glutamate transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046125 pyrimidine deoxyribonucleoside metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0030276 clathrin binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001570 vasculogenesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016575 histone deacetylation P 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0051183 vitamin transporter activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004407 histone deacetylase activity F 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0051181 cofactor transport P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0050757 thymidylate synthase biosynthesis P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006743 ubiquinone metabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0050873 brown fat cell differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015099 nickel ion transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008629 induction of apoptosis by intracellular signals P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005384 manganese ion transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0030374 ligand-dependent nuclear receptor transcription coactivator activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0031074 nucleocytoplasmic shuttling complex C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008508 bile acid\:sodium symporter activity F 0 1 5 0 20 0 1 5 0 20 -0.161 1 1 0042596 fear response P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0047750 cholestenol delta-isomerase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0006656 phosphatidylcholine biosynthesis P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0019794 nonprotein amino acid metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006591 ornithine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045930 negative regulation of progression through mitotic cell cycle P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046934 phosphatidylinositol-4\,5-bisphosphate 3-kinase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045426 quinone cofactor biosynthesis P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0045672 positive regulation of osteoclast differentiation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0000030 mannosyltransferase activity F 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0051222 positive regulation of protein transport P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008215 spermine metabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0046824 positive regulation of nucleocytoplasmic transport P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005513 detection of calcium ion P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042307 positive regulation of protein import into nucleus P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004027 alcohol sulfotransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0009967 positive regulation of signal transduction P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030353 fibroblast growth factor receptor antagonist activity F 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0045780 positive regulation of bone resorption P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008216 spermidine metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016272 prefoldin complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0005953 CAAX-protein geranylgeranyltransferase complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0004962 endothelin receptor activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0045088 regulation of innate immune response P 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0042993 positive regulation of transcription factor import into nucleus P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004638 phosphoribosylaminoimidazole carboxylase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008484 sulfuric ester hydrolase activity F 0 0 7 0 0 0 1 10 0 10 -0.161 1 1 0009211 pyrimidine deoxyribonucleoside triphosphate metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0000036 acyl carrier activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042439 ethanolamine and derivative metabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0019695 choline metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0047179 platelet-activating factor acetyltransferase activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0001656 metanephros development P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006189 ’de novo’ IMP biosynthesis P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0009320 phosphoribosylaminoimidazole carboxylase complex C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001822 kidney development P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009071 serine family amino acid catabolism P 0 0 0 0 0 0 1 6 0 16.66667 -0.161 1 1 0008133 collagenase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0001655 urogenital system development P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0045103 intermediate filament-based process P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0043030 regulation of macrophage activation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046113 nucleobase catabolism P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0005078 MAP-kinase scaffold activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005684 major (U2-dependent) spliceosome C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016661 oxidoreductase activity\, acting on other nitrogenous compounds as donors F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0019563 glycerol catabolism P 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0015842 synaptic vesicle amine transport P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0009120 deoxyribonucleoside metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0004366 glycerol-3-phosphate O-acyltransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016663 oxidoreductase activity\, acting on other nitrogenous compounds as donors\, oxygen as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0030532 small nuclear ribonucleoprotein complex C 0 0 1 0 0 0 1 2 0 50 -0.161 1 1 0042375 quinone cofactor metabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0015094 lead ion transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0043195 terminal button C 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0045277 respiratory chain complex IV C 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0016623 oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, oxygen as acceptor F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006401 RNA catabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0015355 monocarboxylate porter activity F 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0016414 O-octanoyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0008523 sodium-dependent multivitamin transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0005851 eukaryotic translation initiation factor 2B complex C 0 1 3 0 33.33333 0 1 3 0 33.33333 -0.161 1 1 0008286 insulin receptor signaling pathway P 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0030407 formimidoyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006972 hyperosmotic response P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0019768 high affinity IgE receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0008467 heparin-glucosamine 3-O-sulfotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016415 octanoyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006020 myo-inositol metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016594 glycine binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016743 carboxyl- and carbamoyltransferase activity F 0 0 1 0 0 0 1 3 0 33.33333 -0.161 1 1 0019767 IgE receptor activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0009219 pyrimidine deoxyribonucleotide metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0016595 glutamate binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0007587 sugar utilization P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016167 glial cell line-derived neurotrophic factor receptor activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016151 nickel ion binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0035066 positive regulation of histone acetylation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0016455 RNA polymerase II transcription mediator activity F 0 1 2 0 50 0 1 2 0 50 -0.161 1 1 0016553 base conversion or substitution editing P 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0006402 mRNA catabolism P 0 0 0 0 0 0 1 3 0 33.33333 -0.161 1 1 0005665 DNA-directed RNA polymerase II\, core complex C 0 1 4 0 25 0 1 4 0 25 -0.161 1 1 0007584 response to nutrient P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0006072 glycerol-3-phosphate metabolism P 0 0 3 0 0 0 1 7 0 14.28571 -0.161 1 1 0006071 glycerol metabolism P 0 0 3 0 0 0 1 10 0 10 -0.161 1 1 0046870 cadmium ion binding F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0042594 response to starvation P 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015086 cadmium ion transporter activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity F 0 1 1 0 100 0 1 1 0 100 -0.161 1 1 0046174 polyol catabolism P 0 0 0 0 0 0 1 4 0 25 -0.161 1 1 0046131 pyrimidine ribonucleoside metabolism P 0 0 0 0 0 0 1 2 0 50 -0.161 1 1 0017169 CDP-alcohol phosphatidyltransferase activity F 0 0 0 0 0 0 1 1 0 100 -0.161 1 1 0007399 nervous system development P 1 43 60 2.325581 71.66666 2 89 126 2.247191 70.63492 -0.178 1 1 0048731 system development P 0 0 0 0 0 2 89 127 2.247191 70.07874 -0.178 1 1 0006457 protein folding P 1 47 131 2.12766 35.87786 1 48 138 2.083333 34.78261 -0.203 1 1 0016881 acid-amino acid ligase activity F 0 0 0 0 0 1 49 228 2.040816 21.49123 -0.224 1 1 0008033 tRNA processing P 0 2 14 0 14.28571 0 2 18 0 11.11111 -0.228 1 1 0030168 platelet activation P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0004069 aspartate transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006788 heme oxidation P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007015 actin filament organization P 0 2 3 0 66.66666 0 2 5 0 40 -0.228 1 1 0050954 sensory perception of mechanical stimulus P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0016529 sarcoplasmic reticulum C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0005842 cytosolic large ribosomal subunit (sensu Eukaryota) C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0030019 tryptase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016291 acyl-CoA thioesterase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0043198 dendritic shaft C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004176 ATP-dependent peptidase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0030139 endocytic vesicle C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006270 DNA replication initiation P 0 1 8 0 12.5 0 2 9 0 22.22222 -0.228 1 1 0008294 calcium- and calmodulin-responsive adenylate cyclase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004392 heme oxygenase (decyclizing) activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0001649 osteoblast differentiation P 0 1 2 0 50 0 2 4 0 50 -0.228 1 1 0019344 cysteine biosynthesis P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0030674 protein binding\, bridging F 0 1 5 0 20 0 2 6 0 33.33333 -0.228 1 1 0016528 sarcoplasm C 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0004105 choline-phosphate cytidylyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045162 clustering of voltage-gated sodium channels P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005605 basal lamina C 0 2 2 0 100 0 2 7 0 28.57143 -0.228 1 1 0000781 chromosome\, telomeric region C 0 2 2 0 100 0 2 3 0 66.66666 -0.228 1 1 0004531 deoxyribonuclease II activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0048019 receptor antagonist activity F 0 1 1 0 100 0 2 5 0 40 -0.228 1 1 0005583 fibrillar collagen C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0005830 cytosolic ribosome (sensu Eukaryota) C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0030158 protein xylosyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007026 negative regulation of microtubule depolymerization P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0003706 ligand-regulated transcription factor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0003906 DNA-(apurinic or apyrimidinic site) lyase activity F 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0006213 pyrimidine nucleoside metabolism P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004948 calcitonin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0000070 mitotic sister chromatid segregation P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0007605 sensory perception of sound P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0006012 galactose metabolism P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0017134 fibroblast growth factor binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0051057 positive regulation of small GTPase mediated signal transduction P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0008526 phosphatidylinositol transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045649 regulation of macrophage differentiation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0005522 profilin binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0045125 bioactive lipid receptor activity F 0 0 0 0 0 0 2 7 0 28.57143 -0.228 1 1 0042156 zinc-mediated transcriptional activator activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016215 CoA desaturase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004696 glycogen synthase kinase 3 activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004994 somatostatin receptor activity F 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0001540 beta-amyloid binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005639 integral to nuclear inner membrane C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006509 membrane protein ectodomain proteolysis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0007193 G-protein signaling\, adenylate cyclase inhibiting pathway P 0 2 2 0 100 0 2 3 0 66.66666 -0.228 1 1 0030863 cortical cytoskeleton C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015926 glucosidase activity F 0 1 4 0 25 0 2 7 0 28.57143 -0.228 1 1 0007034 vacuolar transport P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0000776 kinetochore C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0003994 aconitate hydratase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0006505 GPI anchor metabolism P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0016363 nuclear matrix C 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0007040 lysosome organization and biogenesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0051016 barbed-end actin filament capping P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0019213 deacetylase activity F 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0007041 lysosomal transport P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045188 regulation of circadian sleep/wake cycle\, non-REM sleep P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0042627 chylomicron C 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0048156 tau protein binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016072 rRNA metabolism P 0 0 0 0 0 0 2 18 0 11.11111 -0.228 1 1 0008898 homocysteine S-methyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045666 positive regulation of neuron differentiation P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005021 vascular endothelial growth factor receptor activity F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.228 1 1 0016641 oxidoreductase activity\, acting on the CH-NH2 group of donors\, oxygen as acceptor F 0 0 0 0 0 0 2 9 0 22.22222 -0.228 1 1 0018987 osmoregulation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006740 NADPH regeneration P 0 0 0 0 0 0 2 7 0 28.57143 -0.228 1 1 0042347 negative regulation of NF-kappaB import into nucleus P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006909 phagocytosis P 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0004017 adenylate kinase activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0046083 adenine metabolism P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0000012 single strand break repair P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008533 astacin activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0004909 interleukin-1\, Type I\, activating receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006739 NADP metabolism P 0 0 0 0 0 0 2 7 0 28.57143 -0.228 1 1 0042992 negative regulation of transcription factor import into nucleus P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042308 negative regulation of protein import into nucleus P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045334 clathrin-coated endocytic vesicle C 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0007413 axonal fasciculation P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0017110 nucleoside-diphosphatase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0042744 hydrogen peroxide catabolism P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0050517 inositol hexakisphosphate kinase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009166 nucleotide catabolism P 0 1 2 0 50 0 2 4 0 50 -0.228 1 1 0008585 female gonad development P 0 0 1 0 0 0 2 3 0 66.66666 -0.228 1 1 0019959 interleukin-8 binding F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042698 menstrual cycle P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0003810 protein-glutamine gamma-glutamyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0016165 lipoxygenase activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0046579 positive regulation of Ras protein signal transduction P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0030261 chromosome condensation P 0 0 1 0 0 0 2 5 0 40 -0.228 1 1 0031647 regulation of protein stability P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004949 cannabinoid receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016812 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in cyclic amides F 0 0 2 0 0 0 2 4 0 50 -0.228 1 1 0016282 eukaryotic 43S preinitiation complex C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016864 intramolecular oxidoreductase activity\, transposing S-S bonds F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0000819 sister chromatid segregation P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004576 oligosaccharyl transferase activity F 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0003987 acetate-CoA ligase activity F 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0004926 non-G-protein coupled 7TM receptor activity F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.228 1 1 0008252 nucleotidase activity F 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0016600 flotillin complex C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009791 post-embryonic development P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045296 cadherin binding F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0004053 arginase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0015321 sodium-dependent phosphate transporter activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0004712 protein threonine/tyrosine kinase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0009725 response to hormone stimulus P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004030 aldehyde dehydrogenase [NAD(P)+] activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0007194 negative regulation of adenylate cyclase activity P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007033 vacuole organization and biogenesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042396 phosphagen biosynthesis P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0016670 oxidoreductase activity\, acting on sulfur group of donors\, oxygen as acceptor F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0050679 positive regulation of epithelial cell proliferation P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0016999 antibiotic metabolism P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0046660 female sex differentiation P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0016899 oxidoreductase activity\, acting on the CH-OH group of donors\, oxygen as acceptor F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016714 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced pteridine as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0006612 protein targeting to membrane P 0 1 1 0 100 0 2 5 0 40 -0.228 1 1 0042116 macrophage activation P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0006687 glycosphingolipid metabolism P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0045444 fat cell differentiation P 0 0 1 0 0 0 2 3 0 66.66666 -0.228 1 1 0046545 development of primary female sexual characteristics P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0000189 nuclear translocation of MAPK P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008605 protein kinase CK2 regulator activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0031229 intrinsic to nuclear inner membrane C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0051693 actin filament capping P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0030835 negative regulation of actin filament depolymerization P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0030834 regulation of actin filament depolymerization P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0030042 actin filament depolymerization P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0006268 DNA unwinding during replication P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0051350 negative regulation of lyase activity P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0031280 negative regulation of cyclase activity P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004311 farnesyltranstransferase activity F 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0006703 estrogen biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004942 anaphylatoxin receptor activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0007253 cytoplasmic sequestering of NF-kappaB P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005883 neurofilament C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0051059 NF-kappaB binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006364 rRNA processing P 0 2 17 0 11.76471 0 2 17 0 11.76471 -0.228 1 1 0005732 small nucleolar ribonucleoprotein complex C 0 2 19 0 10.52632 0 2 19 0 10.52632 -0.228 1 1 0045429 positive regulation of nitric oxide biosynthesis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0016499 orexin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005185 neurohypophyseal hormone activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008171 O-methyltransferase activity F 0 0 2 0 0 0 2 7 0 28.57143 -0.228 1 1 0050771 negative regulation of axonogenesis P 0 1 2 0 50 0 2 4 0 50 -0.228 1 1 0015349 thyroid hormone transporter activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0042176 regulation of protein catabolism P 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0009067 aspartate family amino acid biosynthesis P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0000775 chromosome\, pericentric region C 0 0 8 0 0 0 2 10 0 20 -0.228 1 1 0004359 glutaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045542 positive regulation of cholesterol biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008073 ornithine decarboxylase inhibitor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005637 nuclear inner membrane C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008514 organic anion transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0042748 circadian sleep/wake cycle\, non-REM sleep P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008624 induction of apoptosis by extracellular signals P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004308 exo-alpha-sialidase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016018 cyclosporin A binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0006892 post-Golgi transport P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0005802 Golgi trans face C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007292 female gamete generation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0017000 antibiotic biosynthesis P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0009066 aspartate family amino acid metabolism P 0 0 0 0 0 0 2 7 0 28.57143 -0.228 1 1 0016884 carbon-nitrogen ligase activity\, with glutamine as amido-N-donor F 0 0 0 0 0 0 2 6 0 33.33333 -0.228 1 1 0030151 molybdenum ion binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0008333 endosome to lysosome transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0030173 integral to Golgi membrane C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009082 branched chain family amino acid biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004084 branched-chain-amino-acid transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045663 positive regulation of myoblast differentiation P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0019967 interleukin-1\, Type I\, activating binding F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0018445 prothoracicotrophic hormone activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0019079 viral genome replication P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0042063 gliogenesis P 0 0 1 0 0 0 2 3 0 66.66666 -0.228 1 1 0016547 RNA editing P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016556 mRNA modification P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0048265 response to pain P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045005 maintenance of fidelity during DNA-dependent DNA replication P 0 0 0 0 0 0 2 6 0 33.33333 -0.228 1 1 0006166 purine ribonucleoside salvage P 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0016742 hydroxymethyl-\, formyl- and related transferase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0004372 glycine hydroxymethyltransferase activity F 0 0 2 0 0 0 2 5 0 40 -0.228 1 1 0006032 chitin catabolism P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0004568 chitinase activity F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0030193 regulation of blood coagulation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016822 hydrolase activity\, acting on acid carbon-carbon bonds F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0009620 response to fungi P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0019058 viral infectious cycle P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0015278 calcium-release channel activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0005217 intracellular ligand-gated ion channel activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0051259 protein oligomerization P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0046851 negative regulation of bone remodeling P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0018209 peptidyl-serine modification P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008240 tripeptidyl-peptidase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006779 porphyrin biosynthesis P 0 0 2 0 0 0 2 7 0 28.57143 -0.228 1 1 0045026 plasma membrane fusion P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016823 hydrolase activity\, acting on acid carbon-carbon bonds\, in ketonic substances F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004887 thyroid hormone receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045638 negative regulation of myeloid cell differentiation P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0009003 signal peptidase activity F 0 1 5 0 20 0 2 7 0 28.57143 -0.228 1 1 0006465 signal peptide processing P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0008339 MP kinase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009755 hormone-mediated signaling P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005128 erythropoietin receptor binding F 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0016114 terpenoid biosynthesis P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0009241 polyisoprenoid biosynthesis P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0046246 terpene biosynthesis P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0006721 terpenoid metabolism P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0007588 excretion P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0016096 polyisoprenoid metabolism P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0031369 translation initiation factor binding F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0015368 calcium\:cation antiporter activity F 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0030104 water homeostasis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0004960 thromboxane receptor activity F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0016646 oxidoreductase activity\, acting on the CH-NH group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 0 2 8 0 25 -0.228 1 1 0045012 MHC class II receptor activity F 0 2 9 0 22.22222 0 2 9 0 22.22222 -0.228 1 1 0019884 antigen presentation\, exogenous antigen P 0 2 9 0 22.22222 0 2 9 0 22.22222 -0.228 1 1 0042593 glucose homeostasis P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0006544 glycine metabolism P 0 0 2 0 0 0 2 9 0 22.22222 -0.228 1 1 0042402 biogenic amine catabolism P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0042219 amino acid derivative catabolism P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0030195 negative regulation of blood coagulation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042214 terpene metabolism P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0045098 type III intermediate filament C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005148 prolactin receptor binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005131 growth hormone receptor binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0042597 periplasmic space C 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004991 parathyroid hormone receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004103 choline kinase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016893 endonuclease activity\, active with either ribo- or deoxyribonucleic acids and producing 5’-phosphomonoesters F 0 0 0 0 0 0 2 11 0 18.18182 -0.228 1 1 0045540 regulation of cholesterol biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0050810 regulation of steroid biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0046889 positive regulation of lipid biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0046890 regulation of lipid biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0009077 histidine family amino acid catabolism P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0030312 external encapsulating structure C 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0019911 structural constituent of myelin sheath F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0019218 regulation of steroid metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0030313 cell envelope C 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0030866 cortical actin cytoskeleton organization and biogenesis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0016421 CoA carboxylase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016885 ligase activity\, forming carbon-carbon bonds F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0004768 stearoyl-CoA 9-desaturase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016978 lipoate-protein ligase B activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0003729 mRNA binding F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0019166 trans-2-enoyl-CoA reductase (NADPH) activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0001607 neuromedin U receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045940 positive regulation of steroid metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006688 glycosphingolipid biosynthesis P 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0045657 positive regulation of monocyte differentiation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045639 positive regulation of myeloid cell differentiation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0003704 specific RNA polymerase II transcription factor activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016889 endodeoxyribonuclease activity\, producing 3’-phosphomonoesters F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004918 interleukin-8 receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016944 RNA polymerase II transcription elongation factor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0030864 cortical actin cytoskeleton C 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0031114 regulation of microtubule depolymerization P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0031111 negative regulation of microtubule polymerization or depolymerization P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0008474 palmitoyl-(protein) hydrolase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005178 integrin binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0031110 regulation of microtubule polymerization or depolymerization P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0004622 lysophospholipase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0035252 UDP-xylosyltransferase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042285 xylosyltransferase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016846 carbon-sulfur lyase activity F 0 0 0 0 0 0 2 7 0 28.57143 -0.228 1 1 0001615 thyrotropin releasing hormone and secretagogue-like receptors activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0019894 kinesin binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0007274 neuromuscular synaptic transmission P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0031102 neurite regeneration P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0001541 ovarian follicle development P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007569 cell aging P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016744 transferase activity\, transferring aldehyde or ketonic groups F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006278 RNA-dependent DNA replication P 0 2 12 0 16.66667 0 2 12 0 16.66667 -0.228 1 1 0003724 RNA helicase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006013 mannose metabolism P 0 1 5 0 20 0 2 7 0 28.57143 -0.228 1 1 0048144 fibroblast proliferation P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0007127 meiosis I P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0005523 tropomyosin binding F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0017127 cholesterol transporter activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0015485 cholesterol binding F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0005782 peroxisomal matrix C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0017046 peptide hormone binding F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008453 alanine-glyoxylate transaminase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0031127 alpha(1\,2)-fucosyltransferase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0004499 dimethylaniline monooxygenase (N-oxide-forming) activity F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.228 1 1 0005498 sterol carrier activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0004607 phosphatidylcholine-sterol O-acyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0015433 peptide antigen-transporting ATPase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004559 alpha-mannosidase activity F 0 1 5 0 20 0 2 6 0 33.33333 -0.228 1 1 0051047 positive regulation of secretion P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0050864 regulation of B cell activation P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0020027 hemoglobin metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042036 negative regulation of cytokine biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045072 regulation of interferon-gamma biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0051245 negative regulation of cellular defense response P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0010185 regulation of cellular defense response P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045656 negative regulation of monocyte differentiation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008432 JUN kinase binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0043122 regulation of I-kappaB kinase/NF-kappaB cascade P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004415 hyalurononglucosaminidase activity F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0003964 RNA-directed DNA polymerase activity F 0 2 12 0 16.66667 0 2 12 0 16.66667 -0.228 1 1 0003845 11-beta-hydroxysteroid dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004351 glutamate decarboxylase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008206 bile acid metabolism P 0 1 1 0 100 0 2 3 0 66.66666 -0.228 1 1 0030216 keratinocyte differentiation P 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0046320 regulation of fatty acid oxidation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0000910 cytokinesis P 0 2 2 0 100 0 2 3 0 66.66666 -0.228 1 1 0045833 negative regulation of lipid metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0043406 positive regulation of MAPK activity P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004630 phospholipase D activity F 0 2 2 0 100 0 2 3 0 66.66666 -0.228 1 1 0042829 defense response to pathogen P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045860 positive regulation of protein kinase activity P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004448 isocitrate dehydrogenase activity F 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004690 cyclic nucleotide-dependent protein kinase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006111 regulation of gluconeogenesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0043255 regulation of carbohydrate biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045913 positive regulation of carbohydrate metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045767 regulation of anti-apoptosis P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0048004 antigen presentation\, endogenous peptide antigen P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0046979 TAP2 binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0046978 TAP1 binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0046968 peptide antigen transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005165 neurotrophin receptor binding F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042743 hydrogen peroxide metabolism P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0016504 protease activator activity F 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0006434 seryl-tRNA aminoacylation P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045087 innate immune response P 0 1 2 0 50 0 2 4 0 50 -0.228 1 1 0030188 chaperone regulator activity F 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0005385 zinc ion transporter activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0005381 iron ion transporter activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006891 intra-Golgi transport P 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.228 1 1 0007613 memory P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0005861 troponin complex C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008670 2\,4-dienoyl-CoA reductase (NADPH) activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015459 potassium channel regulator activity F 0 1 3 0 33.33333 0 2 5 0 40 -0.228 1 1 0045661 regulation of myoblast differentiation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004828 serine-tRNA ligase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004931 ATP-gated cation channel activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005313 L-glutamate transporter activity F 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0009081 branched chain family amino acid metabolism P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0006046 N-acetylglucosamine catabolism P 0 0 0 0 0 0 2 6 0 33.33333 -0.228 1 1 0004726 non-membrane spanning protein tyrosine phosphatase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0004104 cholinesterase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004660 protein farnesyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0050773 regulation of dendrite morphogenesis P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0001933 negative regulation of protein amino acid phosphorylation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008107 galactoside 2-alpha-L-fucosyltransferase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0015277 kainate selective glutamate receptor activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0008090 retrograde axon cargo transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009649 entrainment of circadian clock P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0019206 nucleoside kinase activity F 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0004771 sterol esterase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0043174 nucleoside salvage P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0010001 glial cell differentiation P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0043094 metabolic compound salvage P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0042994 cytoplasmic sequestering of transcription factor P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006637 acyl-CoA metabolism P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0043101 purine salvage P 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004800 thyroxine 5’-deiodinase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007090 regulation of S phase of mitotic cell cycle P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0042730 fibrinolysis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0030881 beta-2-microglobulin binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0001932 regulation of protein amino acid phosphorylation P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0016780 phosphotransferase activity\, for other substituted phosphate groups F 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004653 polypeptide N-acetylgalactosaminyltransferase activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0015695 organic cation transport P 0 2 2 0 100 0 2 3 0 66.66666 -0.228 1 1 0015248 sterol transporter activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0000075 cell cycle checkpoint P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016652 oxidoreductase activity\, acting on NADH or NADPH\, NAD or NADP as acceptor F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0006658 phosphatidylserine metabolism P 0 2 3 0 66.66666 0 2 5 0 40 -0.228 1 1 0050667 homocysteine metabolism P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0005890 sodium\:potassium-exchanging ATPase complex C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006043 glucosamine catabolism P 0 0 0 0 0 0 2 6 0 33.33333 -0.228 1 1 0015991 ATP hydrolysis coupled proton transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015379 potassium\:chloride symporter activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0035035 histone acetyltransferase binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0046848 hydroxyapatite binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004718 Janus kinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0000245 spliceosome assembly P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0006302 double-strand break repair P 0 1 1 0 100 0 2 3 0 66.66666 -0.228 1 1 0003726 double-stranded RNA adenosine deaminase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0044247 cellular polysaccharide catabolism P 0 0 0 0 0 0 2 6 0 33.33333 -0.228 1 1 0019238 cyclohydrolase activity F 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0006381 mRNA editing P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008451 X-Pro aminopeptidase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007088 regulation of mitosis P 0 1 2 0 50 0 2 5 0 40 -0.228 1 1 0015825 L-serine transport P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0046348 amino sugar catabolism P 0 0 0 0 0 0 2 6 0 33.33333 -0.228 1 1 0001596 angiotensin type I receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015194 L-serine transporter activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0043407 negative regulation of MAPK activity P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004708 MAP kinase kinase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006030 chitin metabolism P 0 0 2 0 0 0 2 8 0 25 -0.228 1 1 0051220 cytoplasmic sequestering of protein P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0005199 structural constituent of cell wall F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0050435 beta-amyloid metabolism P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0001678 cell glucose homeostasis P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0046426 negative regulation of JAK-STAT cascade P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004032 aldehyde reductase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0031177 phosphopantetheine binding F 0 2 8 0 25 0 2 8 0 25 -0.228 1 1 0050821 protein stabilization P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0018105 peptidyl-serine phosphorylation P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004662 CAAX-protein geranylgeranyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016934 glycine-gated chloride channel activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0042924 neuromedin U binding F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006506 GPI anchor biosynthesis P 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0007266 Rho protein signal transduction P 0 2 3 0 66.66666 0 2 4 0 50 -0.228 1 1 0042979 ornithine decarboxylase regulator activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045077 negative regulation of interferon-gamma biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0046425 regulation of JAK-STAT cascade P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016997 alpha-sialidase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0042108 positive regulation of cytokine biosynthesis P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006783 heme biosynthesis P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0019852 L-ascorbic acid metabolism P 0 1 1 0 100 0 2 3 0 66.66666 -0.228 1 1 0046527 glucosyltransferase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0030027 lamellipodium C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0007217 tachykinin signaling pathway P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004165 dodecenoyl-CoA delta-isomerase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0035251 UDP-glucosyltransferase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0030183 B cell differentiation P 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0008520 L-ascorbate\:sodium symporter activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004396 hexokinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0004605 phosphatidate cytidylyltransferase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0001818 negative regulation of cytokine production P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0047485 protein N-terminus binding F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0005657 replication fork C 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0004466 long-chain-acyl-CoA dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0030894 replisome C 0 0 0 0 0 0 2 4 0 50 -0.228 1 1 0018195 peptidyl-arginine modification P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004239 methionyl aminopeptidase activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0030159 receptor signaling complex scaffold activity F 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0042541 hemoglobin biosynthesis P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0050832 defense response to fungi P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0050796 regulation of insulin secretion P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007342 fusion of sperm to egg plasma membrane P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008190 eukaryotic initiation factor 4E binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0042532 negative regulation of tyrosine phosphorylation of STAT protein P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0030288 periplasmic space (sensu Gram-negative Bacteria) C 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0042417 dopamine metabolism P 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0017146 N-methyl-D-aspartate selective glutamate receptor complex C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0000247 C-8 sterol isomerase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0050732 negative regulation of peptidyl-tyrosine phosphorylation P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0018216 peptidyl-arginine methylation P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0042311 vasodilation P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0000795 synaptonemal complex C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0015858 nucleoside transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007589 fluid secretion P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0006829 zinc ion transport P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0045022 early endosome to late endosome transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0008210 estrogen metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0001619 lysosphingolipid and lysophosphatidic acid receptor activity F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.228 1 1 0015909 long-chain fatty acid transport P 0 2 3 0 66.66666 0 2 4 0 50 -0.228 1 1 0015923 mannosidase activity F 0 0 0 0 0 0 2 10 0 20 -0.228 1 1 0009880 embryonic pattern specification P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0019028 viral capsid C 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0045471 response to ethanol P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006406 mRNA export from nucleus P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0045185 maintenance of protein localization P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0045255 hydrogen-translocating F-type ATPase complex C 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0001819 positive regulation of cytokine production P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008443 phosphofructokinase activity F 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0042503 tyrosine phosphorylation of Stat3 protein P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0006098 pentose-phosphate shunt P 0 1 5 0 20 0 2 7 0 28.57143 -0.228 1 1 0007157 heterophilic cell adhesion P 0 2 3 0 66.66666 0 2 5 0 40 -0.228 1 1 0051235 maintenance of localization P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0006548 histidine catabolism P 0 2 4 0 50 0 2 5 0 40 -0.228 1 1 0016857 racemase and epimerase activity\, acting on carbohydrates and derivatives F 0 0 1 0 0 0 2 4 0 50 -0.228 1 1 0004689 phosphorylase kinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0042509 regulation of tyrosine phosphorylation of STAT protein P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0015272 ATP-activated inward rectifier potassium channel activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0017047 adrenocorticotropin-releasing hormone binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009225 nucleotide-sugar metabolism P 0 1 5 0 20 0 2 6 0 33.33333 -0.228 1 1 0030641 hydrogen ion homeostasis P 0 2 2 0 100 0 2 3 0 66.66666 -0.228 1 1 0015467 G-protein activated inward rectifier potassium channel activity F 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0000272 polysaccharide catabolism P 0 0 1 0 0 0 2 6 0 33.33333 -0.228 1 1 0005220 inositol 1\,4\,5-triphosphate-sensitive calcium-release channel activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0050730 regulation of peptidyl-tyrosine phosphorylation P 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0005865 striated muscle thin filament C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0045763 negative regulation of amino acid metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016338 calcium-independent cell-cell adhesion P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0042770 DNA damage response\, signal transduction P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0005956 protein kinase CK2 complex C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006568 tryptophan metabolism P 0 1 1 0 100 0 2 4 0 50 -0.228 1 1 0016715 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced ascorbate as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0016286 small conductance calcium-activated potassium channel activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0005964 phosphorylase kinase complex C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0046488 phosphatidylinositol metabolism P 0 1 1 0 100 0 2 3 0 66.66666 -0.228 1 1 0004966 galanin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009437 carnitine metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008278 cohesin complex C 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0048488 synaptic vesicle endocytosis P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0005025 transforming growth factor beta receptor activity\, type I F 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0006022 aminoglycan metabolism P 0 0 0 0 0 0 2 5 0 40 -0.228 1 1 0030203 glycosaminoglycan metabolism P 0 0 1 0 0 0 2 5 0 40 -0.228 1 1 0042516 regulation of tyrosine phosphorylation of Stat3 protein P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0007062 sister chromatid cohesion P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0016861 intramolecular oxidoreductase activity\, interconverting aldoses and ketoses F 0 0 0 0 0 0 2 9 0 22.22222 -0.228 1 1 0045329 carnitine biosynthesis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0030212 hyaluronan metabolism P 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0005104 fibroblast growth factor receptor binding F 0 1 1 0 100 0 2 5 0 40 -0.228 1 1 0046887 positive regulation of hormone secretion P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0006824 cobalt ion transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015802 basic amino acid transport P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0015755 fructose transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004679 AMP-activated protein kinase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015872 dopamine transport P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0007389 pattern specification P 0 0 1 0 0 0 2 3 0 66.66666 -0.228 1 1 0005158 insulin receptor binding F 0 2 10 0 20 0 2 10 0 20 -0.228 1 1 0042572 retinol metabolism P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0019012 virion C 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0003969 RNA editase activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0019763 immunoglobulin receptor activity F 0 0 0 0 0 0 2 3 0 66.66666 -0.228 1 1 0006085 acetyl-CoA biosynthesis P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0008132 pancreatic elastase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0005080 protein kinase C binding F 0 2 7 0 28.57143 0 2 7 0 28.57143 -0.228 1 1 0004111 creatine kinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0015929 hexosaminidase activity F 0 0 0 0 0 0 2 9 0 22.22222 -0.228 1 1 0006603 phosphocreatine metabolism P 0 1 1 0 100 0 2 3 0 66.66666 -0.228 1 1 0015172 acidic amino acid transporter activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0000082 G1/S transition of mitotic cell cycle P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0042518 negative regulation of tyrosine phosphorylation of Stat3 protein P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0016328 lateral plasma membrane C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009374 biotin binding F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0001726 ruffle C 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0019228 generation of action potential P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0045601 regulation of endothelial cell differentiation P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0000188 inactivation of MAPK activity P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006890 retrograde transport\, Golgi to ER P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015125 bile acid transporter activity F 0 1 1 0 100 0 2 6 0 33.33333 -0.228 1 1 0008390 testosterone 16-alpha-hydroxylase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004705 JUN kinase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0045069 regulation of viral genome replication P 0 1 2 0 50 0 2 3 0 66.66666 -0.228 1 1 0042775 ATP synthesis coupled electron transport (sensu Eukaryota) P 0 0 0 0 0 0 2 14 0 14.28571 -0.228 1 1 0001758 retinal dehydrogenase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0048016 inositol phosphate-mediated signaling P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0031667 response to nutrient levels P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0030178 negative regulation of Wnt receptor signaling pathway P 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0006298 mismatch repair P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0016299 regulator of G-protein signaling activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0031228 intrinsic to Golgi membrane C 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity F 0 2 5 0 40 0 2 5 0 40 -0.228 1 1 0003756 protein disulfide isomerase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0051260 protein homooligomerization P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0015440 peptide-transporting ATPase activity F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0016717 oxidoreductase activity\, acting on paired donors\, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water F 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0046321 positive regulation of fatty acid oxidation P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0000187 activation of MAPK activity P 0 2 4 0 50 0 2 4 0 50 -0.228 1 1 0007210 serotonin receptor signaling pathway P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0009395 phospholipid catabolism P 0 1 4 0 25 0 2 5 0 40 -0.228 1 1 0009651 response to salt stress P 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0016868 intramolecular transferase activity\, phosphotransferases F 0 1 3 0 33.33333 0 2 5 0 40 -0.228 1 1 0005163 nerve growth factor receptor binding F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006636 fatty acid desaturation P 0 2 6 0 33.33333 0 2 6 0 33.33333 -0.228 1 1 0016316 phosphatidylinositol-3\,4-bisphosphate 4-phosphatase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0004116 cGMP-specific phosphodiesterase activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0019864 IgG binding F 0 1 1 0 100 0 2 3 0 66.66666 -0.228 1 1 0008475 procollagen-lysine 5-dioxygenase activity F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0045722 positive regulation of gluconeogenesis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0048002 antigen presentation\, peptide antigen P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0008553 hydrogen-exporting ATPase activity\, phosphorylative mechanism F 0 2 3 0 66.66666 0 2 3 0 66.66666 -0.228 1 1 0045768 positive regulation of anti-apoptosis P 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0046977 TAP binding F 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004993 serotonin receptor activity F 0 2 2 0 100 0 2 2 0 100 -0.228 1 1 0006684 sphingomyelin metabolism P 0 0 0 0 0 0 2 2 0 100 -0.228 1 1 0004951 cholecystokinin receptor activity F 0 1 1 0 100 0 2 2 0 100 -0.228 1 1 0015698 inorganic anion transport P 0 0 0 0 0 1 50 111 2 45.04504 -0.245 1 1 0046903 secretion P 0 0 1 0 0 2 94 131 2.12766 71.75572 -0.258 1 1 0005249 voltage-gated potassium channel activity F 1 39 66 2.564103 59.09091 1 51 80 1.960784 63.75 -0.265 1 1 0050870 positive regulation of T cell activation P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0007019 microtubule depolymerization P 0 1 1 0 100 0 3 6 0 50 -0.28 1 1 0016032 viral life cycle P 0 0 2 0 0 0 3 7 0 42.85714 -0.28 1 1 0051028 mRNA transport P 0 1 1 0 100 0 3 4 0 75 -0.28 1 1 0006564 L-serine biosynthesis P 0 3 6 0 50 0 3 6 0 50 -0.28 1 1 0007223 frizzled-2 signaling pathway P 0 3 20 0 15 0 3 20 0 15 -0.28 1 1 0005954 calcium- and calmodulin-dependent protein kinase complex C 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0016645 oxidoreductase activity\, acting on the CH-NH group of donors F 0 0 0 0 0 0 3 12 0 25 -0.28 1 1 0045261 proton-transporting ATP synthase complex\, catalytic core F(1) C 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0000097 sulfur amino acid biosynthesis P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0050867 positive regulation of cell activation P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0019843 rRNA binding F 0 3 13 0 23.07692 0 3 13 0 23.07692 -0.28 1 1 0050661 NADP binding F 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0016634 oxidoreductase activity\, acting on the CH-CH group of donors\, oxygen as acceptor F 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0030004 monovalent inorganic cation homeostasis P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0004985 opioid receptor activity F 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0030055 cell-matrix junction C 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0046717 acid secretion P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0006405 RNA export from nucleus P 0 1 3 0 33.33333 0 3 7 0 42.85714 -0.28 1 1 0005924 cell-substrate adherens junction C 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0030307 positive regulation of cell growth P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0008538 proteasome activator activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006921 disassembly of cell structures during apoptosis P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0004028 aldehyde dehydrogenase activity F 0 1 2 0 50 0 3 9 0 33.33333 -0.28 1 1 0016160 amylase activity F 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0030262 apoptotic nuclear changes P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0042559 pteridine and derivative biosynthesis P 0 0 0 0 0 0 3 7 0 42.85714 -0.28 1 1 0042135 neurotransmitter catabolism P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0006521 regulation of amino acid metabolism P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0045446 endothelial cell differentiation P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0008406 gonad development P 0 1 1 0 100 0 3 5 0 60 -0.28 1 1 0046146 tetrahydrobiopterin metabolism P 0 0 0 0 0 0 3 5 0 60 -0.28 1 1 0005000 vasopressin receptor activity F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0006003 fructose 2\,6-bisphosphate metabolism P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0046658 anchored to plasma membrane C 0 3 6 0 50 0 3 6 0 50 -0.28 1 1 0016405 CoA-ligase activity F 0 0 1 0 0 0 3 6 0 50 -0.28 1 1 0007568 aging P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0019438 aromatic compound biosynthesis P 0 0 0 0 0 0 3 9 0 33.33333 -0.28 1 1 0046148 pigment biosynthesis P 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0030072 peptide hormone secretion P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0006000 fructose metabolism P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0030865 cortical cytoskeleton organization and biogenesis P 0 1 1 0 100 0 3 4 0 75 -0.28 1 1 0008537 proteasome activator complex C 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0007051 spindle organization and biogenesis P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0007031 peroxisome organization and biogenesis P 0 1 2 0 50 0 3 7 0 42.85714 -0.28 1 1 0006309 DNA fragmentation during apoptosis P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0004785 copper\, zinc superoxide dismutase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0015087 cobalt ion transporter activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0008172 S-methyltransferase activity F 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0016862 intramolecular oxidoreductase activity\, interconverting keto- and enol-groups F 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0016478 negative regulation of translation P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0031225 anchored to membrane C 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0030132 clathrin coat of coated pit C 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0006970 response to osmotic stress P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0018344 protein geranylgeranylation P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0042573 retinoic acid metabolism P 0 2 2 0 100 0 3 3 0 100 -0.28 1 1 0004062 aryl sulfotransferase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0009409 response to cold P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006547 histidine metabolism P 0 1 1 0 100 0 3 7 0 42.85714 -0.28 1 1 0006729 tetrahydrobiopterin biosynthesis P 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0016892 endoribonuclease activity\, producing 3’-phosphomonoesters F 0 0 0 0 0 0 3 16 0 18.75 -0.28 1 1 0042288 MHC class I protein binding F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0009075 histidine family amino acid metabolism P 0 0 0 0 0 0 3 7 0 42.85714 -0.28 1 1 0005537 mannose binding F 0 3 6 0 50 0 3 6 0 50 -0.28 1 1 0004556 alpha-amylase activity F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0019642 anaerobic glycolysis P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0016866 intramolecular transferase activity F 0 0 0 0 0 0 3 12 0 25 -0.28 1 1 0045807 positive regulation of endocytosis P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0042102 positive regulation of T cell proliferation P 0 2 2 0 100 0 3 3 0 100 -0.28 1 1 0005769 early endosome C 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0030832 regulation of actin filament length P 0 0 0 0 0 0 3 11 0 27.27273 -0.28 1 1 0010181 FMN binding F 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.28 1 1 0045936 negative regulation of phosphate metabolism P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0045727 positive regulation of protein biosynthesis P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0005884 actin filament C 0 3 10 0 30 0 3 10 0 30 -0.28 1 1 0006599 phosphagen metabolism P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0015721 bile acid transport P 0 2 2 0 100 0 3 3 0 100 -0.28 1 1 0019002 GMP binding F 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0005791 rough endoplasmic reticulum C 0 2 2 0 100 0 3 5 0 60 -0.28 1 1 0005172 vascular endothelial growth factor receptor binding F 0 2 2 0 100 0 3 3 0 100 -0.28 1 1 0030225 macrophage differentiation P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0030547 receptor inhibitor activity F 0 1 1 0 100 0 3 6 0 50 -0.28 1 1 0005868 cytoplasmic dynein complex C 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0045947 negative regulation of translational initiation P 0 2 2 0 100 0 3 3 0 100 -0.28 1 1 0006306 DNA methylation P 0 3 17 0 17.64706 0 3 17 0 17.64706 -0.28 1 1 0045596 negative regulation of cell differentiation P 0 0 1 0 0 0 3 5 0 60 -0.28 1 1 0008308 voltage-gated ion-selective channel activity F 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0004972 N-methyl-D-aspartate selective glutamate receptor activity F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0019104 DNA N-glycosylase activity F 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0015988 energy coupled proton transport\, against electrochemical gradient P 0 1 2 0 50 0 3 4 0 75 -0.28 1 1 0005871 kinesin complex C 0 3 6 0 50 0 3 6 0 50 -0.28 1 1 0002009 morphogenesis of an epithelium P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0016933 glycine-gated ion channel activity F 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0008154 actin polymerization and/or depolymerization P 0 0 1 0 0 0 3 12 0 25 -0.28 1 1 0009084 glutamine family amino acid biosynthesis P 0 0 0 0 0 0 3 7 0 42.85714 -0.28 1 1 0030073 insulin secretion P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0042708 elastase activity F 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0019674 NAD metabolism P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0004332 fructose-bisphosphate aldolase activity F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0000060 protein import into nucleus\, translocation P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0006939 smooth muscle contraction P 0 0 3 0 0 0 3 7 0 42.85714 -0.28 1 1 0050818 regulation of coagulation P 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0005548 phospholipid transporter activity F 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0006040 amino sugar metabolism P 0 0 0 0 0 0 3 10 0 30 -0.28 1 1 0006590 thyroid hormone generation P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0003876 AMP deaminase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0050671 positive regulation of lymphocyte proliferation P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0006041 glucosamine metabolism P 0 0 0 0 0 0 3 10 0 30 -0.28 1 1 0051251 positive regulation of lymphocyte activation P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0003809 thrombin activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006044 N-acetylglucosamine metabolism P 0 0 1 0 0 0 3 10 0 30 -0.28 1 1 0007346 regulation of progression through mitotic cell cycle P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0015238 drug transporter activity F 0 2 2 0 100 0 3 10 0 30 -0.28 1 1 0035295 tube development P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0008064 regulation of actin polymerization and/or depolymerization P 0 0 0 0 0 0 3 11 0 27.27273 -0.28 1 1 0030323 respiratory tube development P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0019430 removal of superoxide radicals P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0016841 ammonia-lyase activity F 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0006354 RNA elongation P 0 2 6 0 33.33333 0 3 7 0 42.85714 -0.28 1 1 0048675 axon extension P 0 0 0 0 0 0 3 5 0 60 -0.28 1 1 0015893 drug transport P 0 2 2 0 100 0 3 10 0 30 -0.28 1 1 0007507 heart development P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0030553 3’\,5’-cGMP binding F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0019863 IgE binding F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0050768 negative regulation of neurogenesis P 0 0 0 0 0 0 3 5 0 60 -0.28 1 1 0004862 cAMP-dependent protein kinase inhibitor activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006289 nucleotide-excision repair P 0 2 8 0 25 0 3 9 0 33.33333 -0.28 1 1 0042773 ATP synthesis coupled electron transport P 0 1 5 0 20 0 3 17 0 17.64706 -0.28 1 1 0042345 regulation of NF-kappaB import into nucleus P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0003682 chromatin binding F 0 3 14 0 21.42857 0 3 14 0 21.42857 -0.28 1 1 0004703 G-protein coupled receptor kinase activity F 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0005770 late endosome C 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0031109 microtubule polymerization or depolymerization P 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0004667 prostaglandin-D synthase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0005925 focal adhesion C 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0003997 acyl-CoA oxidase activity F 0 2 2 0 100 0 3 3 0 100 -0.28 1 1 0042326 negative regulation of phosphorylation P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0009247 glycolipid biosynthesis P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0042990 regulation of transcription factor import into nucleus P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0030424 axon C 0 2 2 0 100 0 3 3 0 100 -0.28 1 1 0019841 retinol binding F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0000723 telomere maintenance P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006664 glycolipid metabolism P 0 0 0 0 0 0 3 5 0 60 -0.28 1 1 0050839 cell adhesion molecule binding F 0 1 2 0 50 0 3 7 0 42.85714 -0.28 1 1 0005901 caveola C 0 2 3 0 66.66666 0 3 6 0 50 -0.28 1 1 0008601 protein phosphatase type 2A regulator activity F 0 3 6 0 50 0 3 6 0 50 -0.28 1 1 0018149 peptide cross-linking P 0 3 6 0 50 0 3 6 0 50 -0.28 1 1 0006572 tyrosine catabolism P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0007052 mitotic spindle organization and biogenesis P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0019886 antigen processing\, exogenous antigen via MHC class II P 0 3 10 0 30 0 3 10 0 30 -0.28 1 1 0016080 synaptic vesicle targeting P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0009583 detection of light stimulus P 0 0 0 0 0 0 3 5 0 60 -0.28 1 1 0045058 T cell selection P 0 2 2 0 100 0 3 4 0 75 -0.28 1 1 0008022 protein C-terminus binding F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0001603 vasopressin-like receptor activity F 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0000922 spindle pole C 0 2 4 0 50 0 3 5 0 60 -0.28 1 1 0006109 regulation of carbohydrate metabolism P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0042991 transcription factor import into nucleus P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0008900 hydrogen\:potassium-exchanging ATPase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0048169 regulation of long-term neuronal synaptic plasticity P 0 2 3 0 66.66666 0 3 4 0 75 -0.28 1 1 0018108 peptidyl-tyrosine phosphorylation P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0007602 phototransduction P 0 3 4 0 75 0 3 5 0 60 -0.28 1 1 0004939 beta-adrenergic receptor activity F 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0004767 sphingomyelin phosphodiesterase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0018212 peptidyl-tyrosine modification P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0005903 brush border C 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.28 1 1 0043025 cell soma C 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0001696 gastric acid secretion P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0018348 protein amino acid geranylgeranylation P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0051224 negative regulation of protein transport P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0042348 NF-kappaB import into nucleus P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0042391 regulation of membrane potential P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0046489 phosphoinositide biosynthesis P 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0016307 phosphatidylinositol phosphate kinase activity F 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0005160 transforming growth factor beta receptor binding F 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0016878 acid-thiol ligase activity F 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0030509 BMP signaling pathway P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0004035 alkaline phosphatase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0042828 response to pathogen P 0 1 1 0 100 0 3 4 0 75 -0.28 1 1 0000794 condensed nuclear chromosome C 0 1 1 0 100 0 3 4 0 75 -0.28 1 1 0045761 regulation of adenylate cyclase activity P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0001669 acrosome C 0 3 3 0 100 0 3 4 0 75 -0.28 1 1 0042095 interferon-gamma biosynthesis P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0004740 [pyruvate dehydrogenase (lipoamide)] kinase activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0046823 negative regulation of nucleocytoplasmic transport P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0050792 regulation of viral life cycle P 0 1 1 0 100 0 3 4 0 75 -0.28 1 1 0004179 membrane alanyl aminopeptidase activity F 0 3 8 0 37.5 0 3 8 0 37.5 -0.28 1 1 0046912 transferase activity\, transferring acyl groups\, acyl groups converted into alkyl on transfer F 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0045744 negative regulation of G-protein coupled receptor protein signaling pathway P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0015377 cation\:chloride symporter activity F 0 1 3 0 33.33333 0 3 5 0 60 -0.28 1 1 0008088 axon cargo transport P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0030130 clathrin coat of trans-Golgi network vesicle C 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.28 1 1 0004937 alpha1-adrenergic receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0016599 caveolar membrane C 0 1 3 0 33.33333 0 3 5 0 60 -0.28 1 1 0045137 development of primary sexual characteristics P 0 0 0 0 0 0 3 5 0 60 -0.28 1 1 0009991 response to extracellular stimulus P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0016755 transferase activity\, transferring amino-acyl groups F 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0009435 NAD biosynthesis P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0000059 protein import into nucleus\, docking P 0 3 10 0 30 0 3 10 0 30 -0.28 1 1 0006940 regulation of smooth muscle contraction P 0 3 3 0 100 0 3 4 0 75 -0.28 1 1 0042589 zymogen granule membrane C 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0051339 regulation of lyase activity P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0015914 phospholipid transport P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0016520 growth hormone-releasing hormone receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0004965 GABA-B receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0016081 synaptic vesicle docking during exocytosis P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0050819 negative regulation of coagulation P 0 1 4 0 25 0 3 6 0 50 -0.28 1 1 0030021 extracellular matrix structural constituent conferring compression resistance F 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0030324 lung development P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0031279 regulation of cyclase activity P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0003993 acid phosphatase activity F 0 3 7 0 42.85714 0 3 7 0 42.85714 -0.28 1 1 0000270 peptidoglycan metabolism P 0 2 2 0 100 0 3 6 0 50 -0.28 1 1 0019370 leukotriene biosynthesis P 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0005765 lysosomal membrane C 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0003857 3-hydroxyacyl-CoA dehydrogenase activity F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0001764 neuron migration P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0007172 signal complex formation P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0004522 pancreatic ribonuclease activity F 0 3 13 0 23.07692 0 3 13 0 23.07692 -0.28 1 1 0043112 receptor metabolism P 0 0 0 0 0 0 3 3 0 100 -0.28 1 1 0030149 sphingolipid catabolism P 0 1 1 0 100 0 3 4 0 75 -0.28 1 1 0006914 autophagy P 0 3 6 0 50 0 3 7 0 42.85714 -0.28 1 1 0016284 alanine aminopeptidase activity F 0 0 0 0 0 0 3 8 0 37.5 -0.28 1 1 0006527 arginine catabolism P 0 2 3 0 66.66666 0 3 4 0 75 -0.28 1 1 0030855 epithelial cell differentiation P 0 2 2 0 100 0 3 4 0 75 -0.28 1 1 0016713 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced iron-sulfur protein as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 3 5 0 60 -0.28 1 1 0016854 racemase and epimerase activity F 0 0 0 0 0 0 3 7 0 42.85714 -0.28 1 1 0050678 regulation of epithelial cell proliferation P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0016358 dendrite morphogenesis P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0016638 oxidoreductase activity\, acting on the CH-NH2 group of donors F 0 0 0 0 0 0 3 10 0 30 -0.28 1 1 0045927 positive regulation of growth P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0004716 receptor signaling protein tyrosine kinase activity F 0 1 1 0 100 0 3 4 0 75 -0.28 1 1 0001515 opioid peptide activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006304 DNA modification P 0 0 2 0 0 0 3 19 0 15.78947 -0.28 1 1 0017056 structural constituent of nuclear pore F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0050828 regulation of liquid surface tension P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0045670 regulation of osteoclast differentiation P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0007585 respiratory gaseous exchange P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006305 DNA alkylation P 0 0 0 0 0 0 3 17 0 17.64706 -0.28 1 1 0045124 regulation of bone resorption P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0008376 acetylgalactosaminyltransferase activity F 0 0 0 0 0 0 3 7 0 42.85714 -0.28 1 1 0003988 acetyl-CoA C-acyltransferase activity F 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0045923 positive regulation of fatty acid metabolism P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0042113 B cell activation P 0 1 2 0 50 0 3 7 0 42.85714 -0.28 1 1 0008408 3’-5’ exonuclease activity F 0 2 6 0 33.33333 0 3 14 0 21.42857 -0.28 1 1 0043113 receptor clustering P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0006526 arginine biosynthesis P 0 3 6 0 50 0 3 6 0 50 -0.28 1 1 0007260 tyrosine phosphorylation of STAT protein P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0001882 nucleoside binding F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0004969 histamine receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0004999 vasoactive intestinal polypeptide receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0008320 protein carrier activity F 0 3 12 0 25 0 3 12 0 25 -0.28 1 1 0004274 dipeptidyl-peptidase IV activity F 0 3 5 0 60 0 3 5 0 60 -0.28 1 1 0007173 epidermal growth factor receptor signaling pathway P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0000122 negative regulation of transcription from RNA polymerase II promoter P 0 3 4 0 75 0 3 4 0 75 -0.28 1 1 0051325 interphase P 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0007271 synaptic transmission\, cholinergic P 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0030545 receptor regulator activity F 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0006487 protein amino acid N-linked glycosylation P 0 2 7 0 28.57143 0 3 8 0 37.5 -0.28 1 1 0004971 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0045793 positive regulation of cell size P 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0051329 interphase of mitotic cell cycle P 0 0 0 0 0 0 3 6 0 50 -0.28 1 1 0030345 structural constituent of tooth enamel F 0 3 3 0 100 0 3 3 0 100 -0.28 1 1 0030516 regulation of axon extension P 0 2 3 0 66.66666 0 3 5 0 60 -0.28 1 1 0016979 lipoate-protein ligase activity F 0 0 0 0 0 0 3 4 0 75 -0.28 1 1 0019201 nucleotide kinase activity F 0 0 2 0 0 0 3 10 0 30 -0.28 1 1 0003711 transcriptional elongation regulator activity F 0 1 3 0 33.33333 0 3 6 0 50 -0.28 1 1 0042542 response to hydrogen peroxide P 0 1 1 0 100 0 3 3 0 100 -0.28 1 1 0016705 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen F 0 0 1 0 0 1 53 100 1.886792 53 -0.305 1 1 0046875 ephrin receptor binding F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0006879 iron ion homeostasis P 0 4 19 0 21.05263 0 4 19 0 21.05263 -0.323 1 1 0015385 sodium\:hydrogen antiporter activity F 0 4 8 0 50 0 4 8 0 50 -0.323 1 1 0006776 vitamin A metabolism P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0046474 glycerophospholipid biosynthesis P 0 0 0 0 0 0 4 9 0 44.44444 -0.323 1 1 0051236 establishment of RNA localization P 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0004331 fructose-2\,6-bisphosphate 2-phosphatase activity F 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0042588 zymogen granule C 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0048747 muscle fiber development P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0008028 monocarboxylic acid transporter activity F 0 0 0 0 0 0 4 10 0 40 -0.323 1 1 0051168 nuclear export P 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0005942 phosphoinositide 3-kinase complex C 0 4 9 0 44.44444 0 4 9 0 44.44444 -0.323 1 1 0048741 skeletal muscle fiber development P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0006586 indolalkylamine metabolism P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0015807 L-amino acid transport P 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0006563 L-serine metabolism P 0 0 2 0 0 0 4 9 0 44.44444 -0.323 1 1 0004143 diacylglycerol kinase activity F 0 4 11 0 36.36364 0 4 11 0 36.36364 -0.323 1 1 0050657 nucleic acid transport P 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0015198 oligopeptide transporter activity F 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0035004 phosphoinositide 3-kinase activity F 0 0 0 0 0 0 4 10 0 40 -0.323 1 1 0030148 sphingolipid biosynthesis P 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0006570 tyrosine metabolism P 0 0 1 0 0 0 4 5 0 80 -0.323 1 1 0042692 muscle cell differentiation P 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0048637 skeletal muscle development P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0042434 indole derivative metabolism P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0042430 indole and derivative metabolism P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0046578 regulation of Ras protein signal transduction P 0 1 1 0 100 0 4 7 0 57.14286 -0.323 1 1 0045445 myoblast differentiation P 0 2 2 0 100 0 4 4 0 100 -0.323 1 1 0000228 nuclear chromosome C 0 1 3 0 33.33333 0 4 9 0 44.44444 -0.323 1 1 0046916 transition metal ion homeostasis P 0 0 0 0 0 0 4 19 0 21.05263 -0.323 1 1 0015299 solute\:hydrogen antiporter activity F 0 4 7 0 57.14286 0 4 14 0 28.57143 -0.323 1 1 0016591 DNA-directed RNA polymerase II\, holoenzyme C 0 0 0 0 0 0 4 12 0 33.33333 -0.323 1 1 0007595 lactation P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0030111 regulation of Wnt receptor signaling pathway P 0 2 3 0 66.66666 0 4 8 0 50 -0.323 1 1 0015197 peptide transporter activity F 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0050673 epithelial cell proliferation P 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0016569 covalent chromatin modification P 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0045453 bone resorption P 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0042287 MHC protein binding F 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0050658 RNA transport P 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0004955 prostaglandin receptor activity F 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0005778 peroxisomal membrane C 0 3 6 0 50 0 4 7 0 57.14286 -0.323 1 1 0005487 nucleocytoplasmic transporter activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0016799 hydrolase activity\, hydrolyzing N-glycosyl compounds F 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0005604 basement membrane C 0 2 6 0 33.33333 0 4 12 0 33.33333 -0.323 1 1 0030593 neutrophil chemotaxis P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0030140 trans-Golgi network transport vesicle C 0 1 1 0 100 0 4 8 0 50 -0.323 1 1 0008417 fucosyltransferase activity F 0 2 4 0 50 0 4 9 0 44.44444 -0.323 1 1 0010033 response to organic substance P 0 2 2 0 100 0 4 4 0 100 -0.323 1 1 0030316 osteoclast differentiation P 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0015185 L-gamma-aminobutyric acid transporter activity F 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0019217 regulation of fatty acid metabolism P 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0017153 sodium\:dicarboxylate symporter activity F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.323 1 1 0016540 protein autoprocessing P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0043405 regulation of MAPK activity P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0003684 damaged DNA binding F 0 4 11 0 36.36364 0 4 11 0 36.36364 -0.323 1 1 0008199 ferric iron binding F 0 4 19 0 21.05263 0 4 19 0 21.05263 -0.323 1 1 0006403 RNA localization P 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0015804 neutral amino acid transport P 0 1 2 0 50 0 4 8 0 50 -0.323 1 1 0019883 antigen presentation\, endogenous antigen P 0 2 4 0 50 0 4 6 0 66.66666 -0.323 1 1 0004287 prolyl oligopeptidase activity F 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0016778 diphosphotransferase activity F 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0004033 aldo-keto reductase activity F 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0016909 SAP kinase activity F 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0005819 spindle C 0 1 2 0 50 0 4 7 0 57.14286 -0.323 1 1 0017017 MAP kinase phosphatase activity F 0 4 9 0 44.44444 0 4 9 0 44.44444 -0.323 1 1 0006835 dicarboxylic acid transport P 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.323 1 1 0050769 positive regulation of neurogenesis P 0 1 2 0 50 0 4 6 0 66.66666 -0.323 1 1 0004977 melanocortin receptor activity F 0 3 4 0 75 0 4 6 0 66.66666 -0.323 1 1 0007202 phospholipase C activation P 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0016570 histone modification P 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0019835 cytolysis P 0 4 10 0 40 0 4 10 0 40 -0.323 1 1 0016303 phosphatidylinositol 3-kinase activity F 0 4 10 0 40 0 4 10 0 40 -0.323 1 1 0015298 solute\:cation antiporter activity F 0 0 0 0 0 0 4 14 0 28.57143 -0.323 1 1 0019363 pyridine nucleotide biosynthesis P 0 1 3 0 33.33333 0 4 7 0 57.14286 -0.323 1 1 0042043 neurexin binding F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0008213 protein amino acid alkylation P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0004000 adenosine deaminase activity F 0 2 3 0 66.66666 0 4 6 0 66.66666 -0.323 1 1 0006479 protein amino acid methylation P 0 3 4 0 75 0 4 6 0 66.66666 -0.323 1 1 0005978 glycogen biosynthesis P 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0015300 solute\:solute antiporter activity F 0 0 0 0 0 0 4 14 0 28.57143 -0.323 1 1 0009582 detection of abiotic stimulus P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0008137 NADH dehydrogenase (ubiquinone) activity F 0 4 23 0 17.3913 0 4 23 0 17.3913 -0.323 1 1 0048029 monosaccharide binding F 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0004467 long-chain-fatty-acid-CoA ligase activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0007416 synaptogenesis P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0051287 NAD binding F 0 4 33 0 12.12121 0 4 33 0 12.12121 -0.323 1 1 0009112 nucleobase metabolism P 0 0 0 0 0 0 4 10 0 40 -0.323 1 1 0009894 regulation of catabolism P 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0000793 condensed chromosome C 0 1 1 0 100 0 4 5 0 80 -0.323 1 1 0006308 DNA catabolism P 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0042306 regulation of protein import into nucleus P 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0030384 phosphoinositide metabolism P 0 0 1 0 0 0 4 7 0 57.14286 -0.323 1 1 0051056 regulation of small GTPase mediated signal transduction P 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0015934 large ribosomal subunit C 0 2 13 0 15.38461 0 4 15 0 26.66667 -0.323 1 1 0016721 oxidoreductase activity\, acting on superoxide radicals as acceptor F 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0009416 response to light stimulus P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0005415 nucleoside\:sodium symporter activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0006493 protein amino acid O-linked glycosylation P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0048515 spermatid differentiation P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0016840 carbon-nitrogen lyase activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0015026 coreceptor activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0009581 detection of external stimulus P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0040029 regulation of gene expression\, epigenetic P 0 0 0 0 0 0 4 23 0 17.3913 -0.323 1 1 0008094 DNA-dependent ATPase activity F 0 2 11 0 18.18182 0 4 16 0 25 -0.323 1 1 0051347 positive regulation of transferase activity P 0 2 3 0 66.66666 0 4 7 0 57.14286 -0.323 1 1 0030165 PDZ domain binding F 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0042129 regulation of T cell proliferation P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0031903 microbody membrane C 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0004784 superoxide dismutase activity F 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0016597 amino acid binding F 0 3 8 0 37.5 0 4 9 0 44.44444 -0.323 1 1 0007213 acetylcholine receptor signaling\, muscarinic pathway P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0005499 vitamin D binding F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0031672 A band C 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0045766 positive regulation of angiogenesis P 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0004936 alpha-adrenergic receptor activity F 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0009250 glucan biosynthesis P 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0030317 sperm motility P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0000303 response to superoxide P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0035240 dopamine binding F 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0004293 tissue kallikrein activity F 0 4 8 0 50 0 4 8 0 50 -0.323 1 1 0005938 cell cortex C 0 1 1 0 100 0 4 6 0 66.66666 -0.323 1 1 0046466 membrane lipid catabolism P 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0050863 regulation of T cell activation P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0005332 gamma-aminobutyric acid\:sodium symporter activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0004952 dopamine receptor activity F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.323 1 1 0005540 hyaluronic acid binding F 0 4 9 0 44.44444 0 4 9 0 44.44444 -0.323 1 1 0042423 catecholamine biosynthesis P 0 2 4 0 50 0 4 6 0 66.66666 -0.323 1 1 0004198 calpain activity F 0 4 12 0 33.33333 0 4 12 0 33.33333 -0.323 1 1 0005451 monovalent cation\:proton antiporter activity F 0 0 0 0 0 0 4 8 0 50 -0.323 1 1 0006518 peptide metabolism P 0 1 1 0 100 0 4 8 0 50 -0.323 1 1 0007286 spermatid development P 0 2 2 0 100 0 4 6 0 66.66666 -0.323 1 1 0006144 purine base metabolism P 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0006941 striated muscle contraction P 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.323 1 1 0051129 negative regulation of cell organization and biogenesis P 0 0 0 0 0 0 4 10 0 40 -0.323 1 1 0046777 protein amino acid autophosphorylation P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0001609 adenosine receptor activity\, G-protein coupled F 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0005863 striated muscle thick filament C 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.323 1 1 0005310 dicarboxylic acid transporter activity F 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0016832 aldehyde-lyase activity F 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0030500 regulation of bone mineralization P 0 3 5 0 60 0 4 6 0 66.66666 -0.323 1 1 0019229 regulation of vasoconstriction P 0 3 4 0 75 0 4 5 0 80 -0.323 1 1 0009743 response to carbohydrate stimulus P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0042278 purine nucleoside metabolism P 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0030667 secretory granule membrane C 0 1 1 0 100 0 4 4 0 100 -0.323 1 1 0008328 ionotropic glutamate receptor complex C 0 2 2 0 100 0 4 4 0 100 -0.323 1 1 0045834 positive regulation of lipid metabolism P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0004981 muscarinic acetylcholine receptor activity F 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0004668 protein-arginine deiminase activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0016655 oxidoreductase activity\, acting on NADH or NADPH\, quinone or similar compound as acceptor F 0 0 0 0 0 0 4 24 0 16.66667 -0.323 1 1 0004303 estradiol 17-beta-dehydrogenase activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0004957 prostaglandin E receptor activity F 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0017158 regulation of calcium ion-dependent exocytosis P 0 3 3 0 100 0 4 4 0 100 -0.323 1 1 0007163 establishment and/or maintenance of cell polarity P 0 3 3 0 100 0 4 5 0 80 -0.323 1 1 0003746 translation elongation factor activity F 0 4 15 0 26.66667 0 4 15 0 26.66667 -0.323 1 1 0046661 male sex differentiation P 0 2 2 0 100 0 4 4 0 100 -0.323 1 1 0015711 organic anion transport P 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.323 1 1 0005788 endoplasmic reticulum lumen C 0 3 5 0 60 0 4 6 0 66.66666 -0.323 1 1 0009451 RNA modification P 0 0 0 0 0 0 4 9 0 44.44444 -0.323 1 1 0051051 negative regulation of transport P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0016290 palmitoyl-CoA hydrolase activity F 0 4 6 0 66.66666 0 4 6 0 66.66666 -0.323 1 1 0046128 purine ribonucleoside metabolism P 0 0 0 0 0 0 4 7 0 57.14286 -0.323 1 1 0016805 dipeptidase activity F 0 3 4 0 75 0 4 7 0 57.14286 -0.323 1 1 0004974 leukotriene receptor activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0004749 ribose phosphate diphosphokinase activity F 0 4 5 0 80 0 4 5 0 80 -0.323 1 1 0031252 leading edge C 0 0 0 0 0 0 4 5 0 80 -0.323 1 1 0015645 fatty-acid ligase activity F 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0051174 regulation of phosphorus metabolism P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0006310 DNA recombination P 0 3 12 0 25 0 4 13 0 30.76923 -0.323 1 1 0009749 response to glucose stimulus P 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0035250 UDP-galactosyltransferase activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0015718 monocarboxylic acid transport P 0 0 1 0 0 0 4 5 0 80 -0.323 1 1 0019220 regulation of phosphate metabolism P 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0008372 cellular component unknown C 0 4 11 0 36.36364 0 4 11 0 36.36364 -0.323 1 1 0004947 bradykinin receptor activity F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0042325 regulation of phosphorylation P 0 1 2 0 50 0 4 6 0 66.66666 -0.323 1 1 0004245 neprilysin activity F 0 4 7 0 57.14286 0 4 7 0 57.14286 -0.323 1 1 0016408 C-acyltransferase activity F 0 0 0 0 0 0 4 6 0 66.66666 -0.323 1 1 0009746 response to hexose stimulus P 0 0 0 0 0 0 4 4 0 100 -0.323 1 1 0005154 epidermal growth factor receptor binding F 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0050136 NADH dehydrogenase (quinone) activity F 0 0 0 0 0 0 4 23 0 17.3913 -0.323 1 1 0005912 adherens junction C 0 1 1 0 100 0 4 5 0 80 -0.323 1 1 0006275 regulation of DNA replication P 0 3 3 0 100 0 4 5 0 80 -0.323 1 1 0004521 endoribonuclease activity F 0 0 1 0 0 0 4 27 0 14.81481 -0.323 1 1 0006367 transcription initiation from RNA polymerase II promoter P 0 4 8 0 50 0 4 8 0 50 -0.323 1 1 0007046 ribosome biogenesis P 0 2 7 0 28.57143 0 4 24 0 16.66667 -0.323 1 1 0042734 presynaptic membrane C 0 4 4 0 100 0 4 4 0 100 -0.323 1 1 0015114 phosphate transporter activity F 0 0 1 0 0 0 4 7 0 57.14286 -0.323 1 1 0015276 ligand-gated ion channel activity F 0 0 0 0 0 1 54 68 1.851852 79.41177 -0.324 1 1 0001653 peptide receptor activity F 0 0 0 0 0 1 54 86 1.851852 62.7907 -0.324 1 1 0015399 primary active transporter activity F 0 0 0 0 0 1 54 139 1.851852 38.84892 -0.324 1 1 0008528 peptide receptor activity\, G-protein coupled F 0 3 4 0 75 1 54 86 1.851852 62.7907 -0.324 1 1 0006520 amino acid metabolism P 0 10 20 0 50 1 55 136 1.818182 40.44118 -0.343 1 1 0051052 regulation of DNA metabolism P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0000271 polysaccharide biosynthesis P 0 0 0 0 0 0 5 10 0 50 -0.361 1 1 0007249 I-kappaB kinase/NF-kappaB cascade P 0 1 3 0 33.33333 0 5 7 0 71.42857 -0.361 1 1 0006825 copper ion transport P 0 5 6 0 83.33334 0 5 7 0 71.42857 -0.361 1 1 0018346 protein amino acid prenylation P 0 2 5 0 40 0 5 8 0 62.5 -0.361 1 1 0006584 catecholamine metabolism P 0 1 4 0 25 0 5 12 0 41.66667 -0.361 1 1 0043284 biopolymer biosynthesis P 0 0 0 0 0 0 5 10 0 50 -0.361 1 1 0000050 urea cycle P 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0006885 regulation of pH P 0 5 10 0 50 0 5 10 0 50 -0.361 1 1 0016500 protein-hormone receptor activity F 0 1 3 0 33.33333 0 5 9 0 55.55556 -0.361 1 1 0016918 retinal binding F 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.361 1 1 0005744 mitochondrial inner membrane presequence translocase complex C 0 5 8 0 62.5 0 5 8 0 62.5 -0.361 1 1 0051223 regulation of protein transport P 0 0 0 0 0 0 5 5 0 100 -0.361 1 1 0046822 regulation of nucleocytoplasmic transport P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0005212 structural constituent of eye lens F 0 5 11 0 45.45454 0 5 11 0 45.45454 -0.361 1 1 0042098 T cell proliferation P 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0005952 cAMP-dependent protein kinase complex C 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.361 1 1 0006833 water transport P 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0001817 regulation of cytokine production P 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0000305 response to oxygen radical P 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0005283 sodium\:amino acid symporter activity F 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0006559 L-phenylalanine catabolism P 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0007222 frizzled signaling pathway P 0 5 8 0 62.5 0 5 8 0 62.5 -0.361 1 1 0006541 glutamine metabolism P 0 5 7 0 71.42857 0 5 8 0 62.5 -0.361 1 1 0042088 T-helper 1 type immune response P 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0008378 galactosyltransferase activity F 0 1 15 0 6.666667 0 5 21 0 23.80952 -0.361 1 1 0030133 transport vesicle C 0 1 1 0 100 0 5 9 0 55.55556 -0.361 1 1 0004520 endodeoxyribonuclease activity F 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0031328 positive regulation of cellular biosynthesis P 0 0 0 0 0 0 5 5 0 100 -0.361 1 1 0015175 neutral amino acid transporter activity F 0 1 2 0 50 0 5 9 0 55.55556 -0.361 1 1 0045161 neuronal ion channel clustering P 0 3 3 0 100 0 5 5 0 100 -0.361 1 1 0051247 positive regulation of protein metabolism P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0030595 immune cell chemotaxis P 0 1 2 0 50 0 5 6 0 83.33334 -0.361 1 1 0015081 sodium ion transporter activity F 0 0 0 0 0 0 5 24 0 20.83333 -0.361 1 1 0005681 spliceosome complex C 0 5 11 0 45.45454 0 5 11 0 45.45454 -0.361 1 1 0005813 centrosome C 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0019212 phosphatase inhibitor activity F 0 0 0 0 0 0 5 15 0 33.33333 -0.361 1 1 0008276 protein methyltransferase activity F 0 3 4 0 75 0 5 12 0 41.66667 -0.361 1 1 0009314 response to radiation P 0 1 1 0 100 0 5 7 0 71.42857 -0.361 1 1 0003755 peptidyl-prolyl cis-trans isomerase activity F 0 5 11 0 45.45454 0 5 11 0 45.45454 -0.361 1 1 0006469 negative regulation of protein kinase activity P 0 3 5 0 60 0 5 8 0 62.5 -0.361 1 1 0007272 ionic insulation of neurons by glial cells P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0007265 Ras protein signal transduction P 0 1 1 0 100 0 5 8 0 62.5 -0.361 1 1 0009065 glutamine family amino acid catabolism P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0008017 microtubule binding F 0 5 11 0 45.45454 0 5 11 0 45.45454 -0.361 1 1 0042553 cellular nerve ensheathment P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0007270 nerve-nerve synaptic transmission P 0 2 2 0 100 0 5 5 0 100 -0.361 1 1 0030659 cytoplasmic vesicle membrane C 0 1 2 0 50 0 5 7 0 71.42857 -0.361 1 1 0007189 G-protein signaling\, adenylate cyclase activating pathway P 0 3 3 0 100 0 5 5 0 100 -0.361 1 1 0008603 cAMP-dependent protein kinase regulator activity F 0 5 9 0 55.55556 0 5 9 0 55.55556 -0.361 1 1 0016859 cis-trans isomerase activity F 0 0 0 0 0 0 5 11 0 45.45454 -0.361 1 1 0005006 epidermal growth factor receptor activity F 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.361 1 1 0006884 regulation of cell volume P 0 3 3 0 100 0 5 5 0 100 -0.361 1 1 0004953 icosanoid receptor activity F 0 0 0 0 0 0 5 9 0 55.55556 -0.361 1 1 0016894 endonuclease activity\, active with either ribo- or deoxyribonucleic acids and producing 3’-phosphomonoesters F 0 0 0 0 0 0 5 18 0 27.77778 -0.361 1 1 0004954 prostanoid receptor activity F 0 0 0 0 0 0 5 9 0 55.55556 -0.361 1 1 0006769 nicotinamide metabolism P 0 0 0 0 0 0 5 11 0 45.45454 -0.361 1 1 0008360 regulation of cell shape P 0 5 9 0 55.55556 0 5 9 0 55.55556 -0.361 1 1 0005581 collagen C 0 4 12 0 33.33333 0 5 14 0 35.71429 -0.361 1 1 0006720 isoprenoid metabolism P 0 0 0 0 0 0 5 17 0 29.41176 -0.361 1 1 0030574 collagen catabolism P 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0016289 CoA hydrolase activity F 0 0 0 0 0 0 5 7 0 71.42857 -0.361 1 1 0000155 two-component sensor molecule activity F 0 5 8 0 62.5 0 5 8 0 62.5 -0.361 1 1 0006558 L-phenylalanine metabolism P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0015288 porin activity F 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0017137 Rab GTPase binding F 0 5 10 0 50 0 5 10 0 50 -0.361 1 1 0009119 ribonucleoside metabolism P 0 0 0 0 0 0 5 9 0 55.55556 -0.361 1 1 0050770 regulation of axonogenesis P 0 0 0 0 0 0 5 9 0 55.55556 -0.361 1 1 0030100 regulation of endocytosis P 0 2 3 0 66.66666 0 5 6 0 83.33334 -0.361 1 1 0051606 detection of stimulus P 0 0 0 0 0 0 5 8 0 62.5 -0.361 1 1 0043450 alkene biosynthesis P 0 0 0 0 0 0 5 8 0 62.5 -0.361 1 1 0003697 single-stranded DNA binding F 0 4 10 0 40 0 5 11 0 45.45454 -0.361 1 1 0004945 angiotensin type II receptor activity F 0 5 8 0 62.5 0 5 8 0 62.5 -0.361 1 1 0004680 casein kinase activity F 0 4 4 0 100 0 5 6 0 83.33334 -0.361 1 1 0007212 dopamine receptor signaling pathway P 0 5 8 0 62.5 0 5 8 0 62.5 -0.361 1 1 0016709 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, NAD or NADH as one donor\, and incorporation of one atom of oxygen F 0 0 0 0 0 0 5 13 0 38.46154 -0.361 1 1 0003950 NAD+ ADP-ribosyltransferase activity F 0 5 12 0 41.66667 0 5 12 0 41.66667 -0.361 1 1 0051261 protein depolymerization P 0 0 0 0 0 0 5 11 0 45.45454 -0.361 1 1 0015908 fatty acid transport P 0 3 3 0 100 0 5 7 0 71.42857 -0.361 1 1 0009266 response to temperature stimulus P 0 1 1 0 100 0 5 6 0 83.33334 -0.361 1 1 0042721 mitochondrial inner membrane protein insertion complex C 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0015464 acetylcholine receptor activity F 0 1 1 0 100 0 5 6 0 83.33334 -0.361 1 1 0000159 protein phosphatase type 2A complex C 0 5 8 0 62.5 0 5 8 0 62.5 -0.361 1 1 0043233 organelle lumen C 0 0 0 0 0 0 5 7 0 71.42857 -0.361 1 1 0006898 receptor mediated endocytosis P 0 4 4 0 100 0 5 5 0 100 -0.361 1 1 0018958 phenol metabolism P 0 0 0 0 0 0 5 12 0 41.66667 -0.361 1 1 0006903 vesicle targeting P 0 2 2 0 100 0 5 5 0 100 -0.361 1 1 0050808 synapse organization and biogenesis P 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0001595 angiotensin receptor activity F 0 0 0 0 0 0 5 8 0 62.5 -0.361 1 1 0016877 ligase activity\, forming carbon-sulfur bonds F 0 0 0 0 0 0 5 8 0 62.5 -0.361 1 1 0006944 membrane fusion P 0 2 3 0 66.66666 0 5 7 0 71.42857 -0.361 1 1 0045655 regulation of monocyte differentiation P 0 0 0 0 0 0 5 5 0 100 -0.361 1 1 0045664 regulation of neuron differentiation P 0 3 7 0 42.85714 0 5 9 0 55.55556 -0.361 1 1 0009615 response to virus P 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0019627 urea metabolism P 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0042101 T cell receptor complex C 0 5 5 0 100 0 5 5 0 100 -0.361 1 1 0045039 protein import into mitochondrial inner membrane P 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0046883 regulation of hormone secretion P 0 1 2 0 50 0 5 6 0 83.33334 -0.361 1 1 0042136 neurotransmitter biosynthesis P 0 3 4 0 75 0 5 9 0 55.55556 -0.361 1 1 0006775 fat-soluble vitamin metabolism P 0 0 0 0 0 0 5 5 0 100 -0.361 1 1 0042166 acetylcholine binding F 0 0 0 0 0 0 5 6 0 83.33334 -0.361 1 1 0016524 latrotoxin receptor activity F 0 5 8 0 62.5 0 5 8 0 62.5 -0.361 1 1 0006857 oligopeptide transport P 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.361 1 1 0007411 axon guidance P 0 2 4 0 50 0 5 9 0 55.55556 -0.361 1 1 0004673 protein histidine kinase activity F 0 0 0 0 0 0 5 8 0 62.5 -0.361 1 1 0005044 scavenger receptor activity F 0 5 16 0 31.25 0 5 16 0 31.25 -0.361 1 1 0005798 Golgi vesicle C 0 1 1 0 100 0 5 10 0 50 -0.361 1 1 0005416 cation\:amino acid symporter activity F 0 0 0 0 0 0 5 5 0 100 -0.361 1 1 0016620 oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 0 5 34 0 14.70588 -0.361 1 1 0004806 triacylglycerol lipase activity F 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0045428 regulation of nitric oxide biosynthesis P 0 2 2 0 100 0 5 6 0 83.33334 -0.361 1 1 0042035 regulation of cytokine biosynthesis P 0 1 1 0 100 0 5 5 0 100 -0.361 1 1 0015359 amino acid permease activity F 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.361 1 1 0004983 neuropeptide Y receptor activity F 0 4 12 0 33.33333 0 5 13 0 38.46154 -0.361 1 1 0030176 integral to endoplasmic reticulum membrane C 0 5 12 0 41.66667 0 5 12 0 41.66667 -0.361 1 1 0008299 isoprenoid biosynthesis P 0 4 14 0 28.57143 0 5 16 0 31.25 -0.361 1 1 0015833 peptide transport P 0 0 0 0 0 0 5 7 0 71.42857 -0.361 1 1 0004864 protein phosphatase inhibitor activity F 0 5 15 0 33.33333 0 5 15 0 33.33333 -0.361 1 1 0017144 drug metabolism P 0 3 4 0 75 0 5 9 0 55.55556 -0.361 1 1 0030098 lymphocyte differentiation P 0 0 0 0 0 0 5 7 0 71.42857 -0.361 1 1 0003954 NADH dehydrogenase activity F 0 2 4 0 50 0 5 24 0 20.83333 -0.361 1 1 0051348 negative regulation of transferase activity P 0 0 0 0 0 0 5 8 0 62.5 -0.361 1 1 0018342 protein prenylation P 0 0 0 0 0 0 5 8 0 62.5 -0.361 1 1 0031227 intrinsic to endoplasmic reticulum membrane C 0 0 0 0 0 0 5 12 0 41.66667 -0.361 1 1 0015269 calcium-activated potassium channel activity F 0 3 5 0 60 0 5 7 0 71.42857 -0.361 1 1 0019233 sensory perception of pain P 0 5 7 0 71.42857 0 5 7 0 71.42857 -0.361 1 1 0042552 myelination P 0 5 6 0 83.33334 0 5 6 0 83.33334 -0.361 1 1 0042403 thyroid hormone metabolism P 0 2 2 0 100 0 5 5 0 100 -0.361 1 1 0005746 mitochondrial electron transport chain C 0 3 9 0 33.33333 0 5 11 0 45.45454 -0.361 1 1 0016879 ligase activity\, forming carbon-nitrogen bonds F 0 0 0 0 0 1 57 250 1.754386 22.8 -0.381 1 1 0019203 carbohydrate phosphatase activity F 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0016886 ligase activity\, forming phosphoric ester bonds F 0 0 0 0 0 0 6 54 0 11.11111 -0.396 1 1 0043038 amino acid activation P 0 0 0 0 0 0 6 43 0 13.95349 -0.396 1 1 0007032 endosome organization and biogenesis P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0006937 regulation of muscle contraction P 0 3 3 0 100 0 6 7 0 85.71429 -0.396 1 1 0004182 carboxypeptidase A activity F 0 6 18 0 33.33333 0 6 18 0 33.33333 -0.396 1 1 0009126 purine nucleoside monophosphate metabolism P 0 0 0 0 0 0 6 9 0 66.66666 -0.396 1 1 0003899 DNA-directed RNA polymerase activity F 0 6 25 0 24 0 6 27 0 22.22222 -0.396 1 1 0003713 transcription coactivator activity F 0 5 10 0 50 0 6 13 0 46.15385 -0.396 1 1 0007059 chromosome segregation P 0 4 4 0 100 0 6 9 0 66.66666 -0.396 1 1 0016876 ligase activity\, forming aminoacyl-tRNA and related compounds F 0 0 0 0 0 0 6 46 0 13.04348 -0.396 1 1 0008239 dipeptidyl-peptidase activity F 0 2 4 0 50 0 6 11 0 54.54546 -0.396 1 1 0016875 ligase activity\, forming carbon-oxygen bonds F 0 0 0 0 0 0 6 46 0 13.04348 -0.396 1 1 0008452 RNA ligase activity F 0 0 0 0 0 0 6 46 0 13.04348 -0.396 1 1 0030427 site of polarized growth C 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0004536 deoxyribonuclease activity F 0 2 2 0 100 0 6 6 0 100 -0.396 1 1 0015450 protein translocase activity F 0 6 15 0 40 0 6 15 0 40 -0.396 1 1 0005504 fatty acid binding F 0 5 7 0 71.42857 0 6 17 0 35.29412 -0.396 1 1 0016706 oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, 2-oxoglutarate as one donor\, and incorporation of one atom each of oxygen into both donors F 0 2 8 0 25 0 6 16 0 37.5 -0.396 1 1 0042310 vasoconstriction P 0 2 2 0 100 0 6 7 0 85.71429 -0.396 1 1 0019362 pyridine nucleotide metabolism P 0 0 0 0 0 0 6 14 0 42.85714 -0.396 1 1 0042562 hormone binding F 0 3 3 0 100 0 6 7 0 85.71429 -0.396 1 1 0006094 gluconeogenesis P 0 5 9 0 55.55556 0 6 10 0 60 -0.396 1 1 0048471 perinuclear region C 0 6 6 0 100 0 6 6 0 100 -0.396 1 1 0009070 serine family amino acid biosynthesis P 0 0 0 0 0 0 6 9 0 66.66666 -0.396 1 1 0009127 purine nucleoside monophosphate biosynthesis P 0 0 0 0 0 0 6 9 0 66.66666 -0.396 1 1 0017148 negative regulation of protein biosynthesis P 0 2 3 0 66.66666 0 6 7 0 85.71429 -0.396 1 1 0046209 nitric oxide metabolism P 0 0 0 0 0 0 6 9 0 66.66666 -0.396 1 1 0030278 regulation of ossification P 0 2 2 0 100 0 6 8 0 75 -0.396 1 1 0019840 isoprenoid binding F 0 0 0 0 0 0 6 8 0 75 -0.396 1 1 0042254 ribosome biogenesis and assembly P 0 2 19 0 10.52632 0 6 43 0 13.95349 -0.396 1 1 0009074 aromatic amino acid family catabolism P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0051050 positive regulation of transport P 0 0 0 0 0 0 6 6 0 100 -0.396 1 1 0007216 metabotropic glutamate receptor signaling pathway P 0 5 28 0 17.85714 0 6 30 0 20 -0.396 1 1 0004540 ribonuclease activity F 0 1 6 0 16.66667 0 6 40 0 15 -0.396 1 1 0007622 rhythmic behavior P 0 0 0 0 0 0 6 6 0 100 -0.396 1 1 0043039 tRNA aminoacylation P 0 0 0 0 0 0 6 43 0 13.95349 -0.396 1 1 0030282 bone mineralization P 0 2 2 0 100 0 6 8 0 75 -0.396 1 1 0050897 cobalt ion binding F 0 6 8 0 75 0 6 8 0 75 -0.396 1 1 0042087 cell-mediated immune response P 0 1 2 0 50 0 6 7 0 85.71429 -0.396 1 1 0030198 extracellular matrix organization and biogenesis P 0 1 5 0 20 0 6 11 0 54.54546 -0.396 1 1 0030431 sleep P 0 1 1 0 100 0 6 6 0 100 -0.396 1 1 0015250 water channel activity F 0 6 7 0 85.71429 0 6 7 0 85.71429 -0.396 1 1 0050802 circadian sleep/wake cycle\, sleep P 0 0 0 0 0 0 6 6 0 100 -0.396 1 1 0016324 apical plasma membrane C 0 6 13 0 46.15385 0 6 13 0 46.15385 -0.396 1 1 0048512 circadian behavior P 0 0 0 0 0 0 6 6 0 100 -0.396 1 1 0042745 circadian sleep/wake cycle P 0 0 0 0 0 0 6 6 0 100 -0.396 1 1 0042749 regulation of circadian sleep/wake cycle P 0 0 0 0 0 0 6 6 0 100 -0.396 1 1 0005815 microtubule organizing center C 0 1 3 0 33.33333 0 6 9 0 66.66666 -0.396 1 1 0008366 nerve ensheathment P 0 0 1 0 0 0 6 8 0 75 -0.396 1 1 0009167 purine ribonucleoside monophosphate metabolism P 0 0 0 0 0 0 6 9 0 66.66666 -0.396 1 1 0005625 soluble fraction C 0 6 9 0 66.66666 0 6 9 0 66.66666 -0.396 1 1 0005501 retinoid binding F 0 1 1 0 100 0 6 8 0 75 -0.396 1 1 0050778 positive regulation of immune response P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0015145 monosaccharide transporter activity F 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0005375 copper ion transporter activity F 0 5 6 0 83.33334 0 6 8 0 75 -0.396 1 1 0006691 leukotriene metabolism P 0 4 6 0 66.66666 0 6 10 0 60 -0.396 1 1 0004016 adenylate cyclase activity F 0 4 6 0 66.66666 0 6 8 0 75 -0.396 1 1 0006626 protein targeting to mitochondrion P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0006414 translational elongation P 0 5 21 0 23.80952 0 6 22 0 27.27273 -0.396 1 1 0016197 endosome transport P 0 1 1 0 100 0 6 6 0 100 -0.396 1 1 0031327 negative regulation of cellular biosynthesis P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0005891 voltage-gated calcium channel complex C 0 6 11 0 54.54546 0 6 11 0 54.54546 -0.396 1 1 0009890 negative regulation of biosynthesis P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0045637 regulation of myeloid cell differentiation P 0 1 1 0 100 0 6 7 0 85.71429 -0.396 1 1 0016526 G-protein coupled receptor activity\, unknown ligand F 0 6 7 0 85.71429 0 6 7 0 85.71429 -0.396 1 1 0015020 glucuronosyltransferase activity F 0 5 7 0 71.42857 0 6 9 0 66.66666 -0.396 1 1 0003887 DNA-directed DNA polymerase activity F 0 2 10 0 20 0 6 15 0 40 -0.396 1 1 0015758 glucose transport P 0 5 6 0 83.33334 0 6 7 0 85.71429 -0.396 1 1 0030016 myofibril C 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0005355 glucose transporter activity F 0 6 7 0 85.71429 0 6 8 0 75 -0.396 1 1 0042612 MHC class I protein complex C 0 6 25 0 24 0 6 25 0 24 -0.396 1 1 0008144 drug binding F 0 3 3 0 100 0 6 7 0 85.71429 -0.396 1 1 0001508 regulation of action potential P 0 1 1 0 100 0 6 7 0 85.71429 -0.396 1 1 0042611 MHC protein complex C 0 0 0 0 0 0 6 25 0 24 -0.396 1 1 0046879 hormone secretion P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0009168 purine ribonucleoside monophosphate biosynthesis P 0 4 5 0 80 0 6 9 0 66.66666 -0.396 1 1 0006418 tRNA aminoacylation for protein translation P 0 1 10 0 10 0 6 43 0 13.95349 -0.396 1 1 0004812 tRNA ligase activity F 0 1 13 0 7.692307 0 6 46 0 13.04348 -0.396 1 1 0004550 nucleoside diphosphate kinase activity F 0 6 10 0 60 0 6 10 0 60 -0.396 1 1 0006241 CTP biosynthesis P 0 6 10 0 60 0 6 10 0 60 -0.396 1 1 0006183 GTP biosynthesis P 0 6 10 0 60 0 6 10 0 60 -0.396 1 1 0015149 hexose transporter activity F 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0006228 UTP biosynthesis P 0 6 10 0 60 0 6 10 0 60 -0.396 1 1 0005452 inorganic anion exchanger activity F 0 6 8 0 75 0 6 8 0 75 -0.396 1 1 0006801 superoxide metabolism P 0 2 3 0 66.66666 0 6 8 0 75 -0.396 1 1 0005164 tumor necrosis factor receptor binding F 0 6 21 0 28.57143 0 6 21 0 28.57143 -0.396 1 1 0006525 arginine metabolism P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0015749 monosaccharide transport P 0 0 0 0 0 0 6 9 0 66.66666 -0.396 1 1 0045187 regulation of circadian sleep/wake cycle\, sleep P 0 4 4 0 100 0 6 6 0 100 -0.396 1 1 0008645 hexose transport P 0 0 0 0 0 0 6 9 0 66.66666 -0.396 1 1 0046928 regulation of neurotransmitter secretion P 0 6 6 0 100 0 6 6 0 100 -0.396 1 1 0016806 dipeptidyl-peptidase and tripeptidyl-peptidase activity F 0 0 0 0 0 0 6 11 0 54.54546 -0.396 1 1 0000051 urea cycle intermediate metabolism P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0009208 pyrimidine ribonucleoside triphosphate metabolism P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0030224 monocyte differentiation P 0 0 0 0 0 0 6 6 0 100 -0.396 1 1 0044242 cellular lipid catabolism P 0 0 0 0 0 0 6 11 0 54.54546 -0.396 1 1 0042364 water-soluble vitamin biosynthesis P 0 0 0 0 0 0 6 12 0 50 -0.396 1 1 0043292 contractile fiber C 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0016813 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amidines F 0 0 0 0 0 0 6 8 0 75 -0.396 1 1 0030017 sarcomere C 0 0 1 0 0 0 6 10 0 60 -0.396 1 1 0005667 transcription factor complex C 0 3 11 0 27.27273 0 6 20 0 30 -0.396 1 1 0009209 pyrimidine ribonucleoside triphosphate biosynthesis P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0051093 negative regulation of development P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0006221 pyrimidine nucleotide biosynthesis P 0 0 4 0 0 0 6 15 0 40 -0.396 1 1 0006809 nitric oxide biosynthesis P 0 1 3 0 33.33333 0 6 9 0 66.66666 -0.396 1 1 0046051 UTP metabolism P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0009218 pyrimidine ribonucleotide metabolism P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0046039 GTP metabolism P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0043062 extracellular structure organization and biogenesis P 0 0 0 0 0 0 6 11 0 54.54546 -0.396 1 1 0008440 inositol trisphosphate 3-kinase activity F 0 6 6 0 100 0 6 6 0 100 -0.396 1 1 0046036 CTP metabolism P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0051258 protein polymerization P 0 5 15 0 33.33333 0 6 22 0 27.27273 -0.396 1 1 0042044 fluid transport P 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0015491 cation\:cation antiporter activity F 0 0 0 0 0 0 6 12 0 50 -0.396 1 1 0009220 pyrimidine ribonucleotide biosynthesis P 0 0 0 0 0 0 6 10 0 60 -0.396 1 1 0031267 small GTPase binding F 0 0 0 0 0 0 6 13 0 46.15385 -0.396 1 1 0045177 apical part of cell C 0 0 0 0 0 0 6 13 0 46.15385 -0.396 1 1 0004722 protein serine/threonine phosphatase activity F 0 6 11 0 54.54546 0 6 11 0 54.54546 -0.396 1 1 0005372 water transporter activity F 0 0 0 0 0 0 6 7 0 85.71429 -0.396 1 1 0004843 ubiquitin-specific protease activity F 0 0 1 0 0 0 6 41 0 14.63415 -0.396 1 1 0005833 hemoglobin complex C 0 6 10 0 60 0 6 10 0 60 -0.396 1 1 0043414 biopolymer methylation P 0 0 0 0 0 0 6 22 0 27.27273 -0.396 1 1 0005388 calcium-transporting ATPase activity F 0 6 6 0 100 0 6 6 0 100 -0.396 1 1 0006672 ceramide metabolism P 0 4 5 0 80 0 6 8 0 75 -0.396 1 1 0051128 regulation of cell organization and biogenesis P 0 0 0 0 0 0 6 17 0 35.29412 -0.396 1 1 0030426 growth cone C 0 6 7 0 85.71429 0 6 7 0 85.71429 -0.396 1 1 0004221 ubiquitin thiolesterase activity F 0 6 40 0 15 0 6 40 0 15 -0.396 1 1 0042277 peptide binding F 0 3 4 0 75 1 59 93 1.694915 63.44086 -0.417 1 1 0004623 phospholipase A2 activity F 0 5 15 0 33.33333 0 7 17 0 41.17647 -0.428 1 1 0030672 synaptic vesicle membrane C 0 6 8 0 75 0 7 9 0 77.77778 -0.428 1 1 0007420 brain development P 0 7 11 0 63.63636 0 7 12 0 58.33333 -0.428 1 1 0007215 glutamate signaling pathway P 0 1 1 0 100 0 7 31 0 22.58064 -0.428 1 1 0015380 anion exchanger activity F 0 1 1 0 100 0 7 9 0 77.77778 -0.428 1 1 0016493 C-C chemokine receptor activity F 0 7 15 0 46.66667 0 7 15 0 46.66667 -0.428 1 1 0004434 inositol or phosphatidylinositol phosphodiesterase activity F 0 0 0 0 0 0 7 14 0 50 -0.428 1 1 0004629 phospholipase C activity F 0 0 2 0 0 0 7 16 0 43.75 -0.428 1 1 0016494 C-X-C chemokine receptor activity F 0 5 5 0 100 0 7 7 0 100 -0.428 1 1 0004194 pepsin A activity F 0 7 9 0 77.77778 0 7 9 0 77.77778 -0.428 1 1 0015116 sulfate transporter activity F 0 0 0 0 0 0 7 8 0 87.5 -0.428 1 1 0005337 nucleoside transporter activity F 0 3 4 0 75 0 7 8 0 87.5 -0.428 1 1 0015085 calcium ion transporter activity F 0 1 1 0 100 0 7 7 0 100 -0.428 1 1 0016066 cellular defense response (sensu Vertebrata) P 0 1 1 0 100 0 7 8 0 87.5 -0.428 1 1 0004190 aspartic-type endopeptidase activity F 0 0 4 0 0 0 7 13 0 53.84615 -0.428 1 1 0042158 lipoprotein biosynthesis P 0 0 0 0 0 0 7 14 0 50 -0.428 1 1 0046165 alcohol biosynthesis P 0 0 0 0 0 0 7 14 0 50 -0.428 1 1 0006090 pyruvate metabolism P 0 0 0 0 0 0 7 11 0 63.63636 -0.428 1 1 0005248 voltage-gated sodium channel activity F 0 7 9 0 77.77778 0 7 9 0 77.77778 -0.428 1 1 0019957 C-C chemokine binding F 0 0 0 0 0 0 7 15 0 46.66667 -0.428 1 1 0019958 C-X-C chemokine binding F 0 0 0 0 0 0 7 7 0 100 -0.428 1 1 0015108 chloride transporter activity F 0 0 0 0 0 0 7 9 0 77.77778 -0.428 1 1 0050900 immune cell migration P 0 2 2 0 100 0 7 8 0 87.5 -0.428 1 1 0015106 bicarbonate transporter activity F 0 0 0 0 0 0 7 9 0 77.77778 -0.428 1 1 0008641 small protein activating enzyme activity F 0 0 0 0 0 0 7 33 0 21.21212 -0.428 1 1 0005184 neuropeptide hormone activity F 0 3 6 0 50 0 7 10 0 70 -0.428 1 1 0006446 regulation of translational initiation P 0 4 7 0 57.14286 0 7 10 0 70 -0.428 1 1 0015301 anion\:anion antiporter activity F 0 0 0 0 0 0 7 9 0 77.77778 -0.428 1 1 0016775 phosphotransferase activity\, nitrogenous group as acceptor F 0 0 0 0 0 0 7 11 0 63.63636 -0.428 1 1 0004435 phosphoinositide phospholipase C activity F 0 7 14 0 50 0 7 14 0 50 -0.428 1 1 0042089 cytokine biosynthesis P 0 1 1 0 100 0 7 7 0 100 -0.428 1 1 0030425 dendrite C 0 4 6 0 66.66666 0 7 9 0 77.77778 -0.428 1 1 0030170 pyridoxal phosphate binding F 0 7 9 0 77.77778 0 7 9 0 77.77778 -0.428 1 1 0005344 oxygen transporter activity F 0 7 12 0 58.33333 0 7 12 0 58.33333 -0.428 1 1 0016628 oxidoreductase activity\, acting on the CH-CH group of donors\, NAD or NADP as acceptor F 0 0 0 0 0 0 7 7 0 100 -0.428 1 1 0004181 metallocarboxypeptidase activity F 0 0 0 0 0 0 7 19 0 36.84211 -0.428 1 1 0008375 acetylglucosaminyltransferase activity F 0 3 7 0 42.85714 0 7 14 0 50 -0.428 1 1 0006733 oxidoreduction coenzyme metabolism P 0 0 0 0 0 0 7 17 0 41.17647 -0.428 1 1 0009147 pyrimidine nucleoside triphosphate metabolism P 0 0 0 0 0 0 7 12 0 58.33333 -0.428 1 1 0004685 calcium- and calmodulin-dependent protein kinase activity F 0 7 7 0 100 0 7 7 0 100 -0.428 1 1 0006220 pyrimidine nucleotide metabolism P 0 0 0 0 0 0 7 16 0 43.75 -0.428 1 1 0046519 sphingoid metabolism P 0 0 0 0 0 0 7 9 0 77.77778 -0.428 1 1 0008642 ubiquitin-like activating enzyme activity F 0 7 33 0 21.21212 0 7 33 0 21.21212 -0.428 1 1 0016863 intramolecular oxidoreductase activity\, transposing C=C bonds F 0 0 0 0 0 0 7 16 0 43.75 -0.428 1 1 0006958 complement activation\, classical pathway P 0 7 13 0 53.84615 0 7 13 0 53.84615 -0.428 1 1 0007028 cytoplasm organization and biogenesis P 0 0 0 0 0 0 7 45 0 15.55556 -0.428 1 1 0019319 hexose biosynthesis P 0 0 1 0 0 0 7 14 0 50 -0.428 1 1 0001518 voltage-gated sodium channel complex C 0 7 8 0 87.5 0 7 8 0 87.5 -0.428 1 1 0017156 calcium ion-dependent exocytosis P 0 3 4 0 75 0 7 8 0 87.5 -0.428 1 1 0008138 protein tyrosine/serine/threonine phosphatase activity F 0 3 20 0 15 0 7 29 0 24.13793 -0.428 1 1 0000160 two-component signal transduction system (phosphorelay) P 0 7 15 0 46.66667 0 7 15 0 46.66667 -0.428 1 1 0001727 lipid kinase activity F 0 0 0 0 0 0 7 16 0 43.75 -0.428 1 1 0009110 vitamin biosynthesis P 0 0 0 0 0 0 7 13 0 53.84615 -0.428 1 1 0051216 cartilage development P 0 6 8 0 75 0 7 9 0 77.77778 -0.428 1 1 0030106 MHC class I receptor activity F 0 7 27 0 25.92593 0 7 27 0 25.92593 -0.428 1 1 0006497 protein lipidation P 0 0 0 0 0 0 7 14 0 50 -0.428 1 1 0008271 sulfate porter activity F 0 6 7 0 85.71429 0 7 8 0 87.5 -0.428 1 1 0008272 sulfate transport P 0 7 10 0 70 0 7 10 0 70 -0.428 1 1 0006171 cAMP biosynthesis P 0 7 8 0 87.5 0 7 8 0 87.5 -0.428 1 1 0046364 monosaccharide biosynthesis P 0 0 0 0 0 0 7 14 0 50 -0.428 1 1 0009891 positive regulation of biosynthesis P 0 0 0 0 0 0 7 8 0 87.5 -0.428 1 1 0015631 tubulin binding F 0 1 2 0 50 0 7 14 0 50 -0.428 1 1 0045765 regulation of angiogenesis P 0 3 3 0 100 0 7 10 0 70 -0.428 1 1 0048168 regulation of neuronal synaptic plasticity P 0 4 4 0 100 0 7 9 0 77.77778 -0.428 1 1 0001816 cytokine production P 0 0 1 0 0 0 7 8 0 87.5 -0.428 1 1 0046058 cAMP metabolism P 0 0 0 0 0 0 7 8 0 87.5 -0.428 1 1 0016503 pheromone receptor activity F 0 7 78 0 8.974359 0 7 78 0 8.974359 -0.428 1 1 0006650 glycerophospholipid metabolism P 0 0 0 0 0 0 7 13 0 53.84615 -0.428 1 1 0006826 iron ion transport P 0 7 22 0 31.81818 0 7 22 0 31.81818 -0.428 1 1 0042107 cytokine metabolism P 0 0 0 0 0 0 7 7 0 100 -0.428 1 1 0004935 adrenoceptor activity F 0 5 6 0 83.33334 0 7 8 0 87.5 -0.428 1 1 0019905 syntaxin binding F 0 6 6 0 100 0 7 7 0 100 -0.428 1 1 0005247 voltage-gated chloride channel activity F 0 7 18 0 38.88889 0 7 18 0 38.88889 -0.428 1 1 0009156 ribonucleoside monophosphate biosynthesis P 0 2 3 0 66.66666 0 8 12 0 66.66666 -0.457 1 1 0043449 alkene metabolism P 0 0 0 0 0 0 8 13 0 61.53846 -0.457 1 1 0000149 SNARE binding F 0 1 1 0 100 0 8 8 0 100 -0.457 1 1 0007179 transforming growth factor beta receptor signaling pathway P 0 7 7 0 100 0 8 8 0 100 -0.457 1 1 0043086 negative regulation of enzyme activity P 0 0 1 0 0 0 8 12 0 66.66666 -0.457 1 1 0003725 double-stranded RNA binding F 0 8 17 0 47.05882 0 8 17 0 47.05882 -0.457 1 1 0006284 base-excision repair P 0 7 9 0 77.77778 0 8 10 0 80 -0.457 1 1 0007214 gamma-aminobutyric acid signaling pathway P 0 8 12 0 66.66666 0 8 12 0 66.66666 -0.457 1 1 0004527 exonuclease activity F 0 5 15 0 33.33333 0 8 30 0 26.66667 -0.457 1 1 0015285 connexon channel activity F 0 8 15 0 53.33333 0 8 15 0 53.33333 -0.457 1 1 0009124 nucleoside monophosphate biosynthesis P 0 0 0 0 0 0 8 12 0 66.66666 -0.457 1 1 0007548 sex differentiation P 0 3 8 0 37.5 0 8 15 0 53.33333 -0.457 1 1 0030552 3’\,5’-cAMP binding F 0 8 11 0 72.72727 0 8 11 0 72.72727 -0.457 1 1 0016064 humoral defense mechanism (sensu Vertebrata) P 0 0 0 0 0 0 8 14 0 57.14286 -0.457 1 1 0006968 cellular defense response P 0 1 1 0 100 0 8 9 0 88.88889 -0.457 1 1 0051020 GTPase binding F 0 2 6 0 33.33333 0 8 19 0 42.10526 -0.457 1 1 0045597 positive regulation of cell differentiation P 0 1 1 0 100 0 8 8 0 100 -0.457 1 1 0009123 nucleoside monophosphate metabolism P 0 0 0 0 0 0 8 12 0 66.66666 -0.457 1 1 0008373 sialyltransferase activity F 0 5 11 0 45.45454 0 8 15 0 53.33333 -0.457 1 1 0019901 protein kinase binding F 0 4 6 0 66.66666 0 8 17 0 47.05882 -0.457 1 1 0009161 ribonucleoside monophosphate metabolism P 0 0 0 0 0 0 8 12 0 66.66666 -0.457 1 1 0042246 tissue regeneration P 0 6 7 0 85.71429 0 8 9 0 88.88889 -0.457 1 1 0004091 carboxylesterase activity F 0 0 1 0 0 0 8 14 0 57.14286 -0.457 1 1 0016811 hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds\, in linear amides F 0 1 2 0 50 0 8 23 0 34.78261 -0.457 1 1 0016208 AMP binding F 0 0 2 0 0 0 8 13 0 61.53846 -0.457 1 1 0005977 glycogen metabolism P 0 4 8 0 50 0 8 13 0 61.53846 -0.457 1 1 0003702 RNA polymerase II transcription factor activity F 0 4 9 0 44.44444 0 8 14 0 57.14286 -0.457 1 1 0005730 nucleolus C 0 6 10 0 60 0 8 32 0 25 -0.457 1 1 0046068 cGMP metabolism P 0 0 0 0 0 0 8 10 0 80 -0.457 1 1 0045859 regulation of protein kinase activity P 0 2 2 0 100 0 8 12 0 66.66666 -0.457 1 1 0042752 regulation of circadian rhythm P 0 2 2 0 100 0 8 8 0 100 -0.457 1 1 0000302 response to reactive oxygen species P 0 2 2 0 100 0 8 8 0 100 -0.457 1 1 0031099 regeneration P 0 0 0 0 0 0 8 9 0 88.88889 -0.457 1 1 0004869 cysteine protease inhibitor activity F 0 8 24 0 33.33333 0 8 25 0 32 -0.457 1 1 0005243 gap-junction forming channel activity F 0 0 2 0 0 0 8 17 0 47.05882 -0.457 1 1 0005921 gap junction C 0 0 4 0 0 0 8 19 0 42.10526 -0.457 1 1 0007631 feeding behavior P 0 7 7 0 100 0 8 8 0 100 -0.457 1 1 0015932 nucleobase\, nucleoside\, nucleotide and nucleic acid transporter activity F 0 0 0 0 0 0 8 9 0 88.88889 -0.457 1 1 0000226 microtubule cytoskeleton organization and biogenesis P 0 2 10 0 20 0 8 19 0 42.10526 -0.457 1 1 0048589 developmental growth P 0 0 0 0 0 0 8 9 0 88.88889 -0.457 1 1 0042493 response to drug P 0 4 6 0 66.66666 0 8 18 0 44.44444 -0.457 1 1 0046850 regulation of bone remodeling P 0 0 0 0 0 0 8 10 0 80 -0.457 1 1 0005024 transforming growth factor beta receptor activity F 0 6 8 0 75 0 8 10 0 80 -0.457 1 1 0015931 nucleobase\, nucleoside\, nucleotide and nucleic acid transport P 0 0 0 0 0 0 8 12 0 66.66666 -0.457 1 1 0005922 connexon complex C 0 8 15 0 53.33333 0 8 15 0 53.33333 -0.457 1 1 0019825 oxygen binding F 0 8 15 0 53.33333 0 8 16 0 50 -0.457 1 1 0008217 regulation of blood pressure P 0 7 9 0 77.77778 0 8 11 0 72.72727 -0.457 1 1 0006182 cGMP biosynthesis P 0 8 10 0 80 0 8 10 0 80 -0.457 1 1 0005478 intracellular transporter activity F 0 3 6 0 50 0 8 12 0 66.66666 -0.457 1 1 0006073 glucan metabolism P 0 0 0 0 0 0 8 13 0 61.53846 -0.457 1 1 0006471 protein amino acid ADP-ribosylation P 0 8 22 0 36.36364 0 8 22 0 36.36364 -0.457 1 1 0004675 transmembrane receptor protein serine/threonine kinase activity F 0 0 0 0 0 0 8 10 0 80 -0.457 1 1 0004383 guanylate cyclase activity F 0 8 10 0 80 0 8 10 0 80 -0.457 1 1 0004759 serine esterase activity F 0 8 13 0 61.53846 0 8 13 0 61.53846 -0.457 1 1 0051240 positive regulation of organismal physiological process P 0 0 0 0 0 0 8 10 0 80 -0.457 1 1 0004089 carbonate dehydratase activity F 0 8 18 0 44.44444 0 8 18 0 44.44444 -0.457 1 1 0007519 striated muscle development P 0 4 5 0 80 0 8 10 0 80 -0.457 1 1 0006956 complement activation P 0 1 5 0 20 0 9 21 0 42.85714 -0.485 1 1 0001608 nucleotide receptor activity\, G-protein coupled F 0 0 0 0 0 0 9 16 0 56.25 -0.485 1 1 0004180 carboxypeptidase activity F 0 5 11 0 45.45454 0 9 23 0 39.13044 -0.485 1 1 0001614 purinergic nucleotide receptor activity F 0 0 0 0 0 0 9 16 0 56.25 -0.485 1 1 0016568 chromatin modification P 0 4 15 0 26.66667 0 9 28 0 32.14286 -0.485 1 1 0015671 oxygen transport P 0 9 15 0 60 0 9 15 0 60 -0.485 1 1 0042110 T cell activation P 0 3 4 0 75 0 9 11 0 81.81818 -0.485 1 1 0007229 integrin-mediated signaling pathway P 0 9 18 0 50 0 9 18 0 50 -0.485 1 1 0007204 elevation of cytosolic calcium ion concentration P 0 9 11 0 81.81818 0 9 11 0 81.81818 -0.485 1 1 0018193 peptidyl-amino acid modification P 0 0 2 0 0 0 9 16 0 56.25 -0.485 1 1 0005200 structural constituent of cytoskeleton F 0 9 16 0 56.25 0 9 16 0 56.25 -0.485 1 1 0006839 mitochondrial transport P 0 7 8 0 87.5 0 9 10 0 90 -0.485 1 1 0008305 integrin complex C 0 9 25 0 36 0 9 25 0 36 -0.485 1 1 0016502 nucleotide receptor activity F 0 0 0 0 0 0 9 16 0 56.25 -0.485 1 1 0015669 gas transport P 0 0 0 0 0 0 9 15 0 60 -0.485 1 1 0019888 protein phosphatase regulator activity F 0 0 0 0 0 0 9 22 0 40.90909 -0.485 1 1 0019208 phosphatase regulator activity F 0 0 0 0 0 0 9 22 0 40.90909 -0.485 1 1 0006399 tRNA metabolism P 0 0 1 0 0 0 9 65 0 13.84615 -0.485 1 1 0051327 M phase of meiotic cell cycle P 0 0 0 0 0 0 9 13 0 69.23077 -0.485 1 1 0004707 MAP kinase activity F 0 9 14 0 64.28571 0 9 14 0 64.28571 -0.485 1 1 0045263 proton-transporting ATP synthase complex\, coupling factor F(o) C 0 9 11 0 81.81818 0 9 11 0 81.81818 -0.485 1 1 0051480 cytosolic calcium ion homeostasis P 0 0 0 0 0 0 9 11 0 81.81818 -0.485 1 1 0042133 neurotransmitter metabolism P 0 0 0 0 0 0 9 15 0 60 -0.485 1 1 0045028 purinergic nucleotide receptor activity\, G-protein coupled F 0 5 12 0 41.66667 0 9 16 0 56.25 -0.485 1 1 0016323 basolateral plasma membrane C 0 6 7 0 85.71429 0 9 12 0 75 -0.485 1 1 0003712 transcription cofactor activity F 0 2 3 0 66.66666 0 9 18 0 50 -0.485 1 1 0007126 meiosis P 0 6 9 0 66.66666 0 9 13 0 69.23077 -0.485 1 1 0007338 fertilization (sensu Metazoa) P 0 4 6 0 66.66666 0 9 14 0 64.28571 -0.485 1 1 0051321 meiotic cell cycle P 0 0 0 0 0 0 9 13 0 69.23077 -0.485 1 1 0009072 aromatic amino acid family metabolism P 0 4 6 0 66.66666 0 9 14 0 64.28571 -0.485 1 1 0048278 vesicle docking P 0 0 1 0 0 0 10 15 0 66.66666 -0.511 1 1 0017157 regulation of exocytosis P 0 5 6 0 83.33334 0 10 11 0 90.90909 -0.511 1 1 0003995 acyl-CoA dehydrogenase activity F 0 6 7 0 85.71429 0 10 11 0 90.90909 -0.511 1 1 0005351 sugar porter activity F 0 10 25 0 40 0 10 25 0 40 -0.511 1 1 0016676 oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor F 0 0 0 0 0 0 10 20 0 50 -0.511 1 1 0016675 oxidoreductase activity\, acting on heme group of donors F 0 0 0 0 0 0 10 20 0 50 -0.511 1 1 0031300 intrinsic to organelle membrane C 0 0 0 0 0 0 10 17 0 58.82353 -0.511 1 1 0031301 integral to organelle membrane C 0 0 0 0 0 0 10 17 0 58.82353 -0.511 1 1 0015179 L-amino acid transporter activity F 0 0 0 0 0 0 10 11 0 90.90909 -0.511 1 1 0016229 steroid dehydrogenase activity F 0 0 0 0 0 0 10 15 0 66.66666 -0.511 1 1 0004177 aminopeptidase activity F 0 5 13 0 38.46154 0 10 25 0 40 -0.511 1 1 0015002 heme-copper terminal oxidase activity F 0 0 0 0 0 0 10 20 0 50 -0.511 1 1 0051119 sugar transporter activity F 0 0 0 0 0 0 10 28 0 35.71429 -0.511 1 1 0015296 anion\:cation symporter activity F 0 0 0 0 0 0 10 15 0 66.66666 -0.511 1 1 0004129 cytochrome-c oxidase activity F 0 10 20 0 50 0 10 20 0 50 -0.511 1 1 0050767 regulation of neurogenesis P 0 0 0 0 0 0 10 15 0 66.66666 -0.511 1 1 0030693 caspase activity F 0 10 14 0 71.42857 0 10 14 0 71.42857 -0.511 1 1 0042742 defense response to bacteria P 0 10 14 0 71.42857 0 10 15 0 66.66666 -0.511 1 1 0008395 steroid hydroxylase activity F 0 3 3 0 100 0 10 11 0 90.90909 -0.511 1 1 0051338 regulation of transferase activity P 0 0 0 0 0 0 10 15 0 66.66666 -0.511 1 1 0008026 ATP-dependent helicase activity F 0 9 56 0 16.07143 0 10 59 0 16.94915 -0.511 1 1 0006904 vesicle docking during exocytosis P 0 7 10 0 70 0 10 14 0 71.42857 -0.511 1 1 0005654 nucleoplasm C 0 1 1 0 100 0 10 33 0 30.30303 -0.511 1 1 0008146 sulfotransferase activity F 0 3 16 0 18.75 0 10 31 0 32.25806 -0.511 1 1 0009566 fertilization P 0 1 1 0 100 0 10 15 0 66.66666 -0.511 1 1 0008527 taste receptor activity F 0 10 13 0 76.92308 0 10 13 0 76.92308 -0.511 1 1 0015144 carbohydrate transporter activity F 0 0 0 0 0 0 10 28 0 35.71429 -0.511 1 1 0006261 DNA-dependent DNA replication P 0 0 0 0 0 0 10 27 0 37.03704 -0.511 1 1 0008643 carbohydrate transport P 0 7 11 0 63.63636 0 10 26 0 38.46154 -0.511 1 1 0006112 energy reserve metabolism P 0 2 2 0 100 0 10 16 0 62.5 -0.511 1 1 0005768 endosome C 0 5 5 0 100 0 10 11 0 90.90909 -0.511 1 1 0006730 one-carbon compound metabolism P 0 10 21 0 47.61905 0 10 21 0 47.61905 -0.511 1 1 0030308 negative regulation of cell growth P 0 11 13 0 84.61539 0 11 13 0 84.61539 -0.536 1 1 0009617 response to bacteria P 0 0 0 0 0 0 11 17 0 64.70588 -0.536 1 1 0016782 transferase activity\, transferring sulfur-containing groups F 0 0 0 0 0 0 11 35 0 31.42857 -0.536 1 1 0003690 double-stranded DNA binding F 0 10 15 0 66.66666 0 11 16 0 68.75 -0.536 1 1 0042157 lipoprotein metabolism P 0 3 14 0 21.42857 0 11 29 0 37.93103 -0.536 1 1 0005343 organic acid\:sodium symporter activity F 0 0 0 0 0 0 11 18 0 61.11111 -0.536 1 1 0043176 amine binding F 0 0 0 0 0 0 11 17 0 64.70588 -0.536 1 1 0006413 translational initiation P 0 6 20 0 30 0 11 28 0 39.28571 -0.536 1 1 0005201 extracellular matrix structural constituent F 0 8 19 0 42.10526 0 11 23 0 47.82609 -0.536 1 1 0044264 cellular polysaccharide metabolism P 0 0 0 0 0 0 11 26 0 42.30769 -0.536 1 1 0007178 transmembrane receptor protein serine/threonine kinase signaling pathway P 0 2 5 0 40 0 11 14 0 78.57143 -0.536 1 1 0007188 G-protein signaling\, coupled to cAMP nucleotide second messenger P 0 2 2 0 100 0 11 12 0 91.66666 -0.536 1 1 0006635 fatty acid beta-oxidation P 0 11 11 0 100 0 11 11 0 100 -0.536 1 1 0019900 kinase binding F 0 3 3 0 100 0 11 20 0 55 -0.536 1 1 0001633 secretin-like receptor activity F 0 1 1 0 100 0 11 13 0 84.61539 -0.536 1 1 0005242 inward rectifier potassium channel activity F 0 7 7 0 100 0 11 13 0 84.61539 -0.536 1 1 0051094 positive regulation of development P 0 0 0 0 0 0 11 13 0 84.61539 -0.536 1 1 0008287 protein serine/threonine phosphatase complex C 0 6 10 0 60 0 11 18 0 61.11111 -0.536 1 1 0019882 antigen presentation P 0 6 24 0 25 0 11 38 0 28.94737 -0.536 1 1 0019200 carbohydrate kinase activity F 0 0 0 0 0 0 11 18 0 61.11111 -0.536 1 1 0000139 Golgi membrane C 0 9 14 0 64.28571 0 11 17 0 64.70588 -0.536 1 1 0016776 phosphotransferase activity\, phosphate group as acceptor F 0 0 1 0 0 0 11 22 0 50 -0.536 1 1 0030551 cyclic nucleotide binding F 0 0 0 0 0 0 11 14 0 78.57143 -0.536 1 1 0007608 sensory perception of smell P 0 11 17 0 64.70588 0 11 17 0 64.70588 -0.536 1 1 0046915 transition metal ion transporter activity F 0 0 0 0 0 0 11 14 0 78.57143 -0.536 1 1 0050880 regulation of blood vessel size P 0 3 4 0 75 0 11 14 0 78.57143 -0.536 1 1 0007623 circadian rhythm P 0 1 2 0 50 0 11 12 0 91.66666 -0.536 1 1 0004970 ionotropic glutamate receptor activity F 0 4 8 0 50 0 11 16 0 68.75 -0.536 1 1 0045926 negative regulation of growth P 0 0 1 0 0 0 11 14 0 78.57143 -0.536 1 1 0019205 nucleobase\, nucleoside\, nucleotide kinase activity F 0 0 0 0 0 0 11 25 0 44 -0.536 1 1 0005976 polysaccharide metabolism P 0 0 0 0 0 0 11 26 0 42.30769 -0.536 1 1 0045259 proton-transporting ATP synthase complex C 0 0 0 0 0 0 11 15 0 73.33334 -0.536 1 1 0001772 immunological synapse C 0 0 1 0 0 0 11 31 0 35.48387 -0.536 1 1 0045792 negative regulation of cell size P 0 0 0 0 0 0 11 13 0 84.61539 -0.536 1 1 0009116 nucleoside metabolism P 0 6 11 0 54.54546 0 11 20 0 55 -0.536 1 1 0005234 glutamate-gated ion channel activity F 0 11 16 0 68.75 0 11 16 0 68.75 -0.536 1 1 0004683 calmodulin regulated protein kinase activity F 0 1 1 0 100 0 12 13 0 92.30769 -0.56 1 1 0046930 pore complex C 0 0 0 0 0 0 12 22 0 54.54546 -0.56 1 1 0005245 voltage-gated calcium channel activity F 0 12 17 0 70.58823 0 12 18 0 66.66666 -0.56 1 1 0012506 vesicle membrane C 0 1 2 0 50 0 12 17 0 70.58823 -0.56 1 1 0005643 nuclear pore C 0 12 22 0 54.54546 0 12 22 0 54.54546 -0.56 1 1 0019956 chemokine binding F 0 0 0 0 0 0 12 21 0 57.14286 -0.56 1 1 0016684 oxidoreductase activity\, acting on peroxide as acceptor F 0 0 0 0 0 0 12 31 0 38.70968 -0.56 1 1 0016763 transferase activity\, transferring pentosyl groups F 0 0 1 0 0 0 12 32 0 37.5 -0.56 1 1 0009064 glutamine family amino acid metabolism P 0 0 0 0 0 0 12 20 0 60 -0.56 1 1 0050909 sensory perception of taste P 0 11 35 0 31.42857 0 12 38 0 31.57895 -0.56 1 1 0007187 G-protein signaling\, coupled to cyclic nucleotide second messenger P 0 1 1 0 100 0 12 15 0 80 -0.56 1 1 0004950 chemokine receptor activity F 0 1 2 0 50 0 12 21 0 57.14286 -0.56 1 1 0004601 peroxidase activity F 0 9 22 0 40.90909 0 12 31 0 38.70968 -0.56 1 1 0007417 central nervous system development P 0 5 7 0 71.42857 0 12 19 0 63.15789 -0.56 1 1 0051046 regulation of secretion P 0 0 0 0 0 0 12 13 0 92.30769 -0.56 1 1 0042551 neuron maturation P 0 0 0 0 0 0 12 14 0 85.71429 -0.56 1 1 0005892 nicotinic acetylcholine-gated receptor-channel complex C 0 12 12 0 100 0 12 12 0 100 -0.56 1 1 0030125 clathrin vesicle coat C 0 9 18 0 50 0 13 26 0 50 -0.583 1 1 0000377 RNA splicing\, via transesterification reactions with bulged adenosine as nucleophile P 0 0 0 0 0 0 13 26 0 50 -0.583 1 1 0005254 chloride channel activity F 0 4 8 0 50 0 13 28 0 46.42857 -0.583 1 1 0001637 G-protein chemoattractant receptor activity F 0 1 1 0 100 0 13 22 0 59.09091 -0.583 1 1 0007160 cell-matrix adhesion P 0 12 32 0 37.5 0 13 33 0 39.39394 -0.583 1 1 0007018 microtubule-based movement P 0 12 56 0 21.42857 0 13 57 0 22.80702 -0.583 1 1 0051248 negative regulation of protein metabolism P 0 0 0 0 0 0 13 21 0 61.90476 -0.583 1 1 0048167 regulation of synaptic plasticity P 0 6 7 0 85.71429 0 13 16 0 81.25 -0.583 1 1 0031589 cell-substrate adhesion P 0 0 0 0 0 0 13 33 0 39.39394 -0.583 1 1 0006695 cholesterol biosynthesis P 0 12 14 0 85.71429 0 13 15 0 86.66666 -0.583 1 1 0006959 humoral immune response P 0 2 3 0 66.66666 0 13 27 0 48.14815 -0.583 1 1 0000375 RNA splicing\, via transesterification reactions P 0 0 0 0 0 0 13 26 0 50 -0.583 1 1 0051170 nuclear import P 0 0 0 0 0 0 13 31 0 41.93548 -0.583 1 1 0006606 protein import into nucleus P 0 2 13 0 15.38461 0 13 31 0 41.93548 -0.583 1 1 0000398 nuclear mRNA splicing\, via spliceosome P 0 11 23 0 47.82609 0 13 26 0 50 -0.583 1 1 0008483 transaminase activity F 0 1 4 0 25 0 13 18 0 72.22222 -0.583 1 1 0005328 neurotransmitter\:sodium symporter activity F 0 10 14 0 71.42857 0 13 18 0 72.22222 -0.583 1 1 0030118 clathrin coat C 0 0 0 0 0 0 13 27 0 48.14815 -0.583 1 1 0005520 insulin-like growth factor binding F 0 13 18 0 72.22222 0 13 18 0 72.22222 -0.583 1 1 0043005 neuron projection C 0 3 3 0 100 0 13 15 0 86.66666 -0.583 1 1 0030705 cytoskeleton-dependent intracellular transport P 0 0 0 0 0 0 13 57 0 22.80702 -0.583 1 1 0003777 microtubule motor activity F 0 13 45 0 28.88889 0 13 45 0 28.88889 -0.583 1 1 0000502 proteasome complex (sensu Eukaryota) C 0 0 0 0 0 0 14 22 0 63.63636 -0.605 1 1 0016849 phosphorus-oxygen lyase activity F 0 0 2 0 0 0 14 20 0 70 -0.605 1 1 0007586 digestion P 0 9 12 0 75 0 14 17 0 82.35294 -0.605 1 1 0008652 amino acid biosynthesis P 0 8 12 0 66.66666 0 14 27 0 51.85185 -0.605 1 1 0004114 3’\,5’-cyclic-nucleotide phosphodiesterase activity F 0 9 14 0 64.28571 0 14 19 0 73.68421 -0.605 1 1 0004714 transmembrane receptor protein tyrosine kinase activity F 0 6 8 0 75 0 14 31 0 45.16129 -0.605 1 1 0016485 protein processing P 0 5 8 0 62.5 0 14 22 0 63.63636 -0.605 1 1 0008067 metabotropic glutamate\, GABA-B-like receptor activity F 0 10 44 0 22.72727 0 14 49 0 28.57143 -0.605 1 1 0016769 transferase activity\, transferring nitrogenous groups F 0 0 4 0 0 0 14 23 0 60.86956 -0.605 1 1 0048475 coated membrane C 0 0 0 0 0 0 14 32 0 43.75 -0.605 1 1 0030120 vesicle coat C 0 0 0 0 0 0 14 31 0 45.16129 -0.605 1 1 0030117 membrane coat C 0 0 0 0 0 0 14 32 0 43.75 -0.605 1 1 0004298 threonine endopeptidase activity F 0 14 21 0 66.66666 0 14 21 0 66.66666 -0.605 1 1 0005839 proteasome core complex (sensu Eukaryota) C 0 14 21 0 66.66666 0 14 21 0 66.66666 -0.605 1 1 0009975 cyclase activity F 0 0 0 0 0 0 14 22 0 63.63636 -0.605 1 1 0004112 cyclic-nucleotide phosphodiesterase activity F 0 0 0 0 0 0 14 20 0 70 -0.605 1 1 0003743 translation initiation factor activity F 0 14 37 0 37.83784 0 14 37 0 37.83784 -0.605 1 1 0004428 inositol or phosphatidylinositol kinase activity F 0 3 6 0 50 0 14 23 0 60.86956 -0.605 1 1 0005326 neurotransmitter transporter activity F 0 1 1 0 100 0 14 19 0 73.68421 -0.605 1 1 0006665 sphingolipid metabolism P 0 5 6 0 83.33334 0 14 18 0 77.77778 -0.605 1 1 0031072 heat shock protein binding F 0 13 47 0 27.65957 0 14 48 0 29.16667 -0.605 1 1 0008277 regulation of G-protein coupled receptor protein signaling pathway P 0 11 13 0 84.61539 0 14 17 0 82.35294 -0.605 1 1 0005834 heterotrimeric G-protein complex C 0 14 21 0 66.66666 0 14 21 0 66.66666 -0.605 1 1 0007409 axonogenesis P 0 6 6 0 100 0 14 20 0 70 -0.605 1 1 0004386 helicase activity F 0 3 17 0 17.64706 0 14 76 0 18.42105 -0.605 1 1 0005905 coated pit C 0 11 13 0 84.61539 0 14 17 0 82.35294 -0.605 1 1 0005319 lipid transporter activity F 0 8 16 0 50 0 14 23 0 60.86956 -0.605 1 1 0009190 cyclic nucleotide biosynthesis P 0 1 4 0 25 0 15 22 0 68.18182 -0.627 1 1 0043296 apical junction complex C 0 0 0 0 0 0 15 38 0 39.47368 -0.627 1 1 0016327 apicolateral plasma membrane C 0 0 0 0 0 0 15 38 0 39.47368 -0.627 1 1 0000004 biological process unknown P 0 15 22 0 68.18182 0 15 22 0 68.18182 -0.627 1 1 0008235 metalloexopeptidase activity F 0 2 5 0 40 0 15 42 0 35.71429 -0.627 1 1 0009187 cyclic nucleotide metabolism P 0 0 0 0 0 0 15 23 0 65.21739 -0.627 1 1 0019395 fatty acid oxidation P 0 2 2 0 100 0 15 15 0 100 -0.627 1 1 0019717 synaptosome C 0 15 19 0 78.94736 0 15 19 0 78.94736 -0.627 1 1 0030036 actin cytoskeleton organization and biogenesis P 0 10 17 0 58.82353 0 15 35 0 42.85714 -0.627 1 1 0004890 GABA-A receptor activity F 0 15 21 0 71.42857 0 15 21 0 71.42857 -0.627 1 1 0009310 amine catabolism P 0 0 0 0 0 0 15 30 0 50 -0.627 1 1 0006936 muscle contraction P 0 5 7 0 71.42857 0 15 23 0 65.21739 -0.627 1 1 0030141 secretory granule C 0 10 12 0 83.33334 0 15 17 0 88.23529 -0.627 1 1 0000041 transition metal ion transport P 0 0 0 0 0 0 15 33 0 45.45454 -0.627 1 1 0009063 amino acid catabolism P 0 0 0 0 0 0 15 28 0 53.57143 -0.627 1 1 0006445 regulation of translation P 0 8 10 0 80 0 15 21 0 71.42857 -0.627 1 1 0016126 sterol biosynthesis P 0 1 1 0 100 0 15 17 0 88.23529 -0.627 1 1 0008134 transcription factor binding F 0 5 10 0 50 0 15 29 0 51.72414 -0.627 1 1 0019897 extrinsic to plasma membrane C 0 1 1 0 100 0 15 22 0 68.18182 -0.627 1 1 0016790 thiolester hydrolase activity F 0 0 0 0 0 0 15 51 0 29.41176 -0.627 1 1 0004889 nicotinic acetylcholine-activated cation-selective channel activity F 0 15 16 0 93.75 0 15 16 0 93.75 -0.627 1 1 0019933 cAMP-mediated signaling P 0 4 5 0 80 0 15 17 0 88.23529 -0.627 1 1 0016051 carbohydrate biosynthesis P 0 3 9 0 33.33333 0 15 34 0 44.11765 -0.627 1 1 0044270 nitrogen compound catabolism P 0 0 0 0 0 0 15 30 0 50 -0.627 1 1 0005923 tight junction C 0 15 38 0 39.47368 0 15 38 0 39.47368 -0.627 1 1 0050953 sensory perception of light stimulus P 0 0 0 0 0 0 16 27 0 59.25926 -0.647 1 1 0005253 anion channel activity F 0 0 0 0 0 0 16 33 0 48.48485 -0.647 1 1 0050804 regulation of synaptic transmission P 0 2 3 0 66.66666 0 16 20 0 80 -0.647 1 1 0008380 RNA splicing P 0 4 7 0 57.14286 0 16 34 0 47.05882 -0.647 1 1 0015985 energy coupled proton transport\, down electrochemical gradient P 0 0 0 0 0 0 16 47 0 34.04255 -0.647 1 1 0006874 calcium ion homeostasis P 0 7 9 0 77.77778 0 16 20 0 80 -0.647 1 1 0015986 ATP synthesis coupled proton transport P 0 16 47 0 34.04255 0 16 47 0 34.04255 -0.647 1 1 0046933 hydrogen-transporting ATP synthase activity\, rotational mechanism F 0 16 46 0 34.78261 0 16 46 0 34.78261 -0.647 1 1 0007156 homophilic cell adhesion P 0 16 76 0 21.05263 0 16 76 0 21.05263 -0.647 1 1 0046961 hydrogen-transporting ATPase activity\, rotational mechanism F 0 16 46 0 34.78261 0 16 46 0 34.78261 -0.647 1 1 0007601 visual perception P 0 16 26 0 61.53846 0 16 27 0 59.25926 -0.647 1 1 0019935 cyclic-nucleotide-mediated signaling P 0 0 1 0 0 0 16 21 0 76.19048 -0.647 1 1 0015297 antiporter activity F 0 13 16 0 81.25 0 16 31 0 51.6129 -0.647 1 1 0000786 nucleosome C 0 16 64 0 25 0 16 64 0 25 -0.647 1 1 0006753 nucleoside phosphate metabolism P 0 0 0 0 0 0 16 48 0 33.33333 -0.647 1 1 0046034 ATP metabolism P 0 0 0 0 0 0 16 48 0 33.33333 -0.647 1 1 0006754 ATP biosynthesis P 0 0 1 0 0 0 16 48 0 33.33333 -0.647 1 1 0030029 actin filament-based process P 0 0 0 0 0 0 16 36 0 44.44444 -0.647 1 1 0006334 nucleosome assembly P 0 16 74 0 21.62162 0 16 74 0 21.62162 -0.647 1 1 0004620 phospholipase activity F 0 1 3 0 33.33333 0 17 40 0 42.5 -0.667 1 1 0050803 regulation of synapse structure and function P 0 1 2 0 50 0 17 22 0 77.27273 -0.667 1 1 0031497 chromatin assembly P 0 0 0 0 0 0 17 80 0 21.25 -0.667 1 1 0048667 neuron morphogenesis during differentiation P 0 0 0 0 0 0 17 24 0 70.83334 -0.667 1 1 0015103 inorganic anion transporter activity F 0 0 0 0 0 0 17 24 0 70.83334 -0.667 1 1 0048511 rhythmic process P 0 4 5 0 80 0 17 19 0 89.47369 -0.667 1 1 0031175 neurite morphogenesis P 0 1 2 0 50 0 17 24 0 70.83334 -0.667 1 1 0051169 nuclear transport P 0 0 0 0 0 0 17 38 0 44.73684 -0.667 1 1 0005507 copper ion binding F 0 18 38 0 47.36842 0 18 38 0 47.36842 -0.687 1 1 0019898 extrinsic to membrane C 0 2 2 0 100 0 18 26 0 69.23077 -0.687 1 1 0016917 GABA receptor activity F 0 0 0 0 0 0 18 24 0 75 -0.687 1 1 0016469 proton-transporting two-sector ATPase complex C 0 17 47 0 36.17021 0 18 48 0 37.5 -0.687 1 1 0008188 neuropeptide receptor activity F 0 2 2 0 100 0 18 33 0 54.54546 -0.687 1 1 0004519 endonuclease activity F 0 15 33 0 45.45454 0 18 49 0 36.7347 -0.687 1 1 0042923 neuropeptide binding F 0 1 1 0 100 0 18 33 0 54.54546 -0.687 1 1 0015082 di-\, tri-valent inorganic cation transporter activity F 0 0 0 0 0 0 18 21 0 85.71429 -0.687 1 1 0005789 endoplasmic reticulum membrane C 0 10 11 0 90.90909 0 18 33 0 54.54546 -0.687 1 1 0017038 protein import P 0 0 0 0 0 0 18 38 0 47.36842 -0.687 1 1 0008015 circulation P 0 1 1 0 100 0 18 24 0 75 -0.687 1 1 0006119 oxidative phosphorylation P 0 0 0 0 0 0 19 64 0 29.6875 -0.706 1 1 0004553 hydrolase activity\, hydrolyzing O-glycosyl compounds F 0 4 16 0 25 0 19 67 0 28.35821 -0.706 1 1 0042175 nuclear envelope-endoplasmic reticulum network C 0 1 1 0 100 0 19 34 0 55.88235 -0.706 1 1 0006486 protein amino acid glycosylation P 0 12 36 0 33.33333 0 19 48 0 39.58333 -0.706 1 1 0006333 chromatin assembly or disassembly P 0 2 13 0 15.38461 0 19 93 0 20.43011 -0.706 1 1 0006888 ER to Golgi transport P 0 19 29 0 65.51724 0 19 29 0 65.51724 -0.706 1 1 0005635 nuclear membrane C 0 5 6 0 83.33334 0 19 30 0 63.33333 -0.706 1 1 0006260 DNA replication P 0 9 42 0 21.42857 0 19 76 0 25 -0.706 1 1 0046982 protein heterodimerization activity F 0 19 28 0 67.85714 0 19 28 0 67.85714 -0.706 1 1 0009101 glycoprotein biosynthesis P 0 0 0 0 0 0 19 48 0 39.58333 -0.706 1 1 0005126 hematopoietin/interferon-class (D200-domain) cytokine receptor binding F 0 3 10 0 30 0 19 32 0 59.375 -0.706 1 1 0008135 translation factor activity\, nucleic acid binding F 0 1 1 0 100 0 19 57 0 33.33333 -0.706 1 1