2010-2011 Stem Cell Symposium Bio
A Chemical Approach to Cellular Reprogramming
Sheng Ding, PhD
The Scripps Research Institute
Recent advances in stem cell biology may make possible new approaches for the treatment of a number of diseases. A better understanding of molecular mechanisms that control stem cell fate as well as an improved ability to manipulate them are required. Toward these goals, Sheng Ding and members of his lab have developed and implemented high throughput cell-based phenotypic screens of arrayed chemical and gene libraries to identify and further characterize small molecules and genes that can control stem cell fate in various systems. Dr. Ding’s talk will provide latest examples of discovery efforts in his lab that have advanced our ability and understanding toward controlling stem cell fate, including self-renewal, survival, differentiation and reprogramming of pluripotent stem cells.
Sheng Ding is currently Associate Professor in the Department of Chemistry at The Scripps Research Institute in La Jolla, USA. He obtained his B.S. in chemistry with honors from Caltech in 1999, and a Ph.D. in chemistry from Scripps in 2003.