Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Core Faculty

Edward J. Kelly PhD

University of Washington
Associate Professor


Office: 206.685.4641

Active areas of research in the Kelly lab include studies on the function of the “orphan” P450 CYP4V2 in the heritable eye disease Bietti’s Crystalline Dystrophy and ex vivo modeling of human organ physiology and toxicological responses to drug/xenobiotic challenge.  This latter project makes use of “organs on chips” or microphysiological systems (MPS) populated with primary and stem-cell derived cell types to recapitulate two key ADME organs, the liver and kidney.  Recent work is extending MPS technologies to model select human diseases as well as how organs respond to the extreme environment of microgravity on the International Space Station. 

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