Ian R. Sweet PhD
University of Washington
Medicine/Metabolism, Endocrinology and Nutrition
Research Assistant Professor
Dr. Sweet's research focuses on role of metabolic dysregulation on diseases such as diabetes, cancer, and cardiovascular disease. One aspect of Dr Sweet's lab is directed at the generation of pancreatic beta cells from stem cells as a potential source of insulin-producing cells that could be transplanted into patients with diabetes. Accordingly, their group is characterizing essential features of native beta cells that will need to be recreated in beta cells generated ex vivo from stem cells. These studies are being done in collaboration and support of the laboratories of Vincenzo Cirulli (MD, PhD) and Laura Crisa (MD, PhD.), who are newly recruited to ISCRM to focus on this important clinical mission. Dr. Sweet is also the Director of the DERC Islet Cell and Functional Analysis Core that carries out real time analysis of cell function and viability using spectroscopic and imaging techniques. For more information on the DERC Islet Cell Core, visit their website at http://depts.washington.edu/diabetes/biomedcore/ifac.index.html.