Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

Parallel reaction monitoring (PRM) and selected reaction monitoring (SRM) exhibit comparable linearity, dynamic range and precision for targeted quantitative HDL proteomics
Journal of Proteomics, January 2015

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase
Molecular and Cellular Biology, January 2015


An Experimentally Robust Model of Monomeric Apolipoprotein A-I Created from a Chimera of Two X-ray Structures and Molecular Dynamics Simulations.
Biochemistry, December 2014


Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice
Mammalian Genome, December 2014


Myeloperoxidase: a therapeutic target for preventing insulin resistance and the metabolic sequelae of obesity?
Diabetes, December 2014


Parallel microfluidic chemosensitivity testing on individual slice cultures
Lab on a Chip, December 2014


Targeting survival pathways to create infarct-spanning bridges of human embryonic stem cell–derived cardiomyocytes 
The Journal of Thoracic and Cardiovascular Surgery, December 2014


A comparative encyclopedia of DNA elements in the mouse genome
Nature, November 2014


A genome-wide map of adeno-associated virus-mediated human gene targeting
Nature Structural & Molecular Biology, November 2014


Clinical factors associated with high-risk carotid plaque features as assessed by magnetic resonance imaging in patients with established vascular disease (from the AIM-HIGH Study)
The American Journal of Cardiology, November 2014

Conservation of trans-acting circuitry during mammalian regulatory evolution
Nature, November 2014


Disease-in-a-Dish: The Contribution of Patient-Specific Induced Pluripotent Stem Cell Technology to Regenerative Rehabilitation
American Journal of Physical Medicine & Rehabilitation, November 2014


Enhanced Chondrogenic Differentiation of Dental Pulp Stem Cells Using Nanopatterned PEG-GelMA-HA Hydrogels
Tissue Engineering: Part A, November 2014


Gait characteristics in a canine model of X-linked myotubular myopathy
Journal of the Neurological Sciences, November 2014


Gene therapy for inherited muscle diseases: where genetics meets rehabilitation medicine
American Journal of Physical Medicine & Rehabilitation, November 2014


High-risk plaque in the superficial femoral artery of people with peripheral artery disease: Prevalence and associated clinical characteristics
Atherosclerosis, November 2014


Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution
Science, November 2014


Quantification of HDL Particle Concentration by Calibrated Ion Mobility Analysis
Clinical Chemistry, November 2014


Regenerative rehabilitation: a new future?
American Journal of Physical Medicine & Rehabilitation, November 2014


Restraint of the differentiation of mesenchymal stem cells by a nonfouling zwitterionic hydrogel
Angewandte Chemie International Edition, November 2014


Chlamydia pneumoniae infection of lungs and macrophages indirectly stimulates the phenotypic conversion of smooth muscle cells and mesenchymal stem cells: potential roles in vascular calcification and fibrosis
Pathogens and Disease, October 2014

Computational Studies of the Effect of the S23D/S24D Troponin I Mutation on Cardiac Troponin Structural Dynamics
Biophysical Journal, October 2014

Evidence for lysine acetylation in the coat protein of a polerovirus
Journal of General Virology, October 2014


G.P.41: Canine X-linked myotubular myopathy: A dose-finding study of systemic AAV8-MTM1 effects on muscle strength, gait, respiration, neuromuscular function and survival
Neuromuscular Disorders, October 2014

Hypertriglyceridemia, lipemia, and elevated liver enzymes associated with prolonged propofol anesthesia for craniotomy
Therapeutic Drug Monitoring, October 2014


Identification of a Multipotent Self-Renewing Stromal Progenitor Population during Mammalian Kidney Organogenesis
Stem Cell Reports, October 2014


Letter by Murry et al Regarding Article, “Embryonic Stem Cell–Derived Cardiac Myocytes Are Not Ready for Human Trials”
Circulation Research, October 2014


Patient-Specific Metrics of Invasiveness Reveal Significant Prognostic Benefit of Resection in a Predictable Subset of Gliomas
PLOS ONE, October 2014


Poly(lactic-co-glycolic) acid microspheres encapsulated in Pluronic F-127 prolong hirudin delivery and improve functional recovery from a demyelination lesion
Biomaterials, October 2014

Regulator of G-Protein Signaling-5 Is a Marker of Hepatic Stellate Cells and Expression Mediates Response to Liver Injury
PLOS ONE, October 2014


Genome Sequencing of Idiopathic Pulmonary Fibrosis in Conjunction with a Medical School Human Anatomy Course
PLOS ONE, September 2014


Generation and Characterization of a Murine Model of
Bietti Crystalline Dystrophy

Investigative Ophthalmology & Visual Science, September 2014


Neutrophil Extracellular Trap–Derived Enzymes Oxidize High-Density Lipoprotein
Arthritis & Rheumatology, September 2014


Patient, physician and contextual factors are influential in the treatment decision making of older adults newly diagnosed with symptomatic myeloma
Cancer Treatment Communications, September 2014


PKA Phosphorylation of Cardiac Troponin I Modulates Activation and Relaxation Kinetics of Ventricular Myofibrils
Biophysical Journal, September 2014


Respiratory assessment in centronuclear myopathies
Muscle & Nerve, September 2014