Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

O6-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
BBA Clinical, June 2015

Guiding intramuscular diaphragm injections using real-time ultrasound and electromyography
Muscle & Nerve, February 2015


Adeno-associated virus-mediated cancer gene therapy: Current status
Cancer Letters, January 2015


Fine-scale chromatin interaction maps reveal the cis-regulatory landscape of human lincRNA genes
Nature Methods, January 2015


Impaired arteriogenesis in syndecan-1(-/-) mice
Journal of Surgical Research, January 2015


Parallel reaction monitoring (PRM) and selected reaction monitoring (SRM) exhibit comparable linearity, dynamic range and precision for targeted quantitative HDL proteomics
Journal of Proteomics, January 2015

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase
Molecular and Cellular Biology, January 2015


An Experimentally Robust Model of Monomeric Apolipoprotein A-I Created from a Chimera of Two X-ray Structures and Molecular Dynamics Simulations.
Biochemistry, December 2014


Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice
Mammalian Genome, December 2014


Myeloperoxidase: a therapeutic target for preventing insulin resistance and the metabolic sequelae of obesity?
Diabetes, December 2014


Parallel microfluidic chemosensitivity testing on individual slice cultures
Lab on a Chip, December 2014


Targeting survival pathways to create infarct-spanning bridges of human embryonic stem cell–derived cardiomyocytes 
The Journal of Thoracic and Cardiovascular Surgery, December 2014


A comparative encyclopedia of DNA elements in the mouse genome
Nature, November 2014


A genome-wide map of adeno-associated virus-mediated human gene targeting
Nature Structural & Molecular Biology, November 2014


Clinical factors associated with high-risk carotid plaque features as assessed by magnetic resonance imaging in patients with established vascular disease (from the AIM-HIGH Study)
The American Journal of Cardiology, November 2014

Conservation of trans-acting circuitry during mammalian regulatory evolution
Nature, November 2014


Disease-in-a-Dish: The Contribution of Patient-Specific Induced Pluripotent Stem Cell Technology to Regenerative Rehabilitation
American Journal of Physical Medicine & Rehabilitation, November 2014


Enhanced Chondrogenic Differentiation of Dental Pulp Stem Cells Using Nanopatterned PEG-GelMA-HA Hydrogels
Tissue Engineering: Part A, November 2014


Gait characteristics in a canine model of X-linked myotubular myopathy
Journal of the Neurological Sciences, November 2014


Gene therapy for inherited muscle diseases: where genetics meets rehabilitation medicine
American Journal of Physical Medicine & Rehabilitation, November 2014


High-risk plaque in the superficial femoral artery of people with peripheral artery disease: Prevalence and associated clinical characteristics
Atherosclerosis, November 2014


Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution
Science, November 2014


Quantification of HDL Particle Concentration by Calibrated Ion Mobility Analysis
Clinical Chemistry, November 2014


Regenerative rehabilitation: a new future?
American Journal of Physical Medicine & Rehabilitation, November 2014


Restraint of the differentiation of mesenchymal stem cells by a nonfouling zwitterionic hydrogel
Angewandte Chemie International Edition, November 2014