Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

miR-124-9-9* potentiates Ascl1-induced reprogramming of cultured Müller glia
GLIA, May 2016


Metabolic remodeling in early development and cardiomyocyte maturation
Seminars in Cell & Developmental Biology, April 2016


Spatiotemporal control of cardiac anisotropy using dynamic nanotopographic cues
Biomaterials, April 2016


A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae
Developmental Biology, March 2016


Dynamic mass redistribution reveals diverging importance of PDZ-ligands for G protein-coupled receptor pharmacodynamics
Pharmacological Research, March 2016


Self-adjuvanted hyaluronate - antigenic peptide conjugate for transdermal treatment of muscular dystrophy
Biomaterials, March 2016


Silent IL2RG Gene Editing in Human Pluripotent Stem Cells
Molecular Therapy, March 2016


The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice
Journal of Virology, March 2016


AAV6-mediated Cardiac-specific Overexpression of Ribonucleotide Reductase Enhances Myocardial Contractility
Molecular Therapy, February 2016


ADSSL1 mutation relevant to autosomal recessive adolescent onset distal myopathy
Annals of Neurology, February 2016


Finally, We Can Relax: A New Generation of Muscle Models that Incorporate Sarcomere Compliance
Biophysical Journal, February 2016


Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential
Stem Cell Reports, February 2016


Inflammation, Endoleaks, and Aortic Remodeling-The Chicken or the Egg
JAMA Surgery, February 2016



Intracellular Delivery of Proteins with Cell-Penetrating Peptides for Therapeutic Uses in Human Disease
International Journal of Molecular Sciences, February 2016


Ketones Step to the Plate: A Game Changer for Metabolic Remodeling in Heart Failure?
Circulation, February 2016


Niacin Therapy Increases High-Density Lipoprotein Particles and Total Cholesterol Efflux Capacity But Not ABCA1-Specific Cholesterol Efflux in Statin-Treated Subjects
Arteriosclerosis, Thrombosis, and Vascular Biology, February 2016

Novel targets for mitochondrial medicine
Science Translational Medicine, February 2016


Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina
The Journal of Biological Chemistry, February 2016


Proteomic analysis of HDL from inbred mouse strains implicates APOE associated with HDL in reduced cholesterol efflux capacity via the ABCA1 pathway
Journal of Lipid Research, February 2016

Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts
Aging, February 2016


Ultrasound-Based Carotid Elastography for Detection of Vulnerable Atherosclerotic Plaques Validated by Magnetic Resonance Imaging
Ultrasound in Medicine & Biology, February 2016


Understanding Spatial Genome Organization: Methods and Insights
Genomics, Proteomics & Bioinformatics, February 2016


Visualization of Host-Polerovirus Interaction Topologies Using Protein Interaction Reporter Technology
Journal of Virology, February 2016