Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

Processing of voided urine for prostate cancer RNA biomarker analysis
The Prostate, December 2015


Charcot-Marie-Tooth Disease Type 4H Resulting from Compound Heterozygous Mutations in FGD4 from Nonconsanguineous Korean Families
Annals of Human Genetics, November 2015


Conventional Computed Tomography and Axial Magnetic Resonance T2-Weighted Imaging of Horizontal Segment of Middle Cerebral Artery in Moyamoya Disease or Syndrome in Adult Patients
                Journal of Stroke and Cerebrovascular Diseases, November 2015


Transgenic expression of the proneural transcription factor Ascl1 in Müller glia stimulates retinal regeneration in young mice
PNAS, November 2015


Endogenous DUX4 expression in FSHD myotubes is sufficient to cause cell death and disrupts RNA splicing and cell migration pathways
Human Molecular Genetics, October 2015


Gene replacement rescues severe muscle pathology and prolongs survival in myotubularin-deficient mice and dogs
Annals of Translational Medicine, October 2015


Heterogeneity of epigenetic changes at ischemia/reperfusion- and endotoxin-induced acute kidney injury genes
Kidney International, October 2015


Mechanisms and clinical applications of chromosomal instability in lymphoid malignancy
British Journal of Haematology, October 15


MMP-10 Regulates Collagenolytic Activity of Alternatively Activated Resident Macrophages
Journal of Investigative Dermatology, October 2015


Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
                Nature Communications, October 2015

Muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy
                Annals of Translational Medicine, October 2015

Photoreceptor cell fate specification in vertebrates
Development, October 2015


Wnt signaling induces transcription, spatial proximity, and translocation of fusion gene partners in human hematopoietic cells
Blood, October 2015


Adeno-associated virus finds its disease
Nature Genetics, September 2015


Comprehensive identification and analysis of human accelerated regulatory DNA
Genome Research, September 2015


Defined MicroRNAs Induce Aspects of Maturation in Mouse and Human Embryonic-Stem-Cell-Derived Cardiomyocytes
Cell Reports, September 2015


Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes
Development, September 2015


It's never too late to save a photoreceptor
The Journal of Clinical Investigation, September 2015


Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs
Cell Host & Microbe, September 2015


Syngeneic myoblast transplantation improves muscle function in a murine model of X-linked myotubular myopathy
Cell Transplantation, September 2015


The advancement of human pluripotent stem cell-derived therapies into the clinic
Development, September 2015


The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem Cells
Stem Cells, September 2015


Use of Adeno-Associated Virus to Enrich Cardiomyocytes Derived from Human Stem Cells
Human Gene Therapy Clinical Development, September 2015