Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

G.P.41: Canine X-linked myotubular myopathy: A dose-finding study of systemic AAV8-MTM1 effects on muscle strength, gait, respiration, neuromuscular function and survival
Neuromuscular Disorders, October 2014

Poly(lactic-co-glycolic) acid microspheres encapsulated in Pluronic F-127 prolong hirudin delivery and improve functional recovery from a demyelination lesion
Biomaterials, October 2014

Genome Sequencing of Idiopathic Pulmonary Fibrosis in Conjunction with a Medical School Human Anatomy Course
PLOS ONE, September 2014

Neutrophil Extracellular Trap–Derived Enzymes Oxidize High-Density Lipoprotein
Arthritis & Rheumatology, September 2014


PKA Phosphorylation of Cardiac Troponin I Modulates Activation and Relaxation Kinetics of Ventricular Myofibrils
Biophysical Journal, September 2014


Respiratory assessment in centronuclear myopathies
Muscle & Nerve, September 2014


Clinical imaging in regenerative medicine
Nature Biotechnology, August 2014


Coronary involvement in lupus patients: getting sharper pictures with advanced vascular imaging?
Journal of the American College of Cardiology: Cardiovascular Imaging, August 2014

Human papillomavirus type 16 viral load in relation to HIV infection, cervical neoplasia and cancer in Senegal
Cancer Epidemiology, August 2014


Lenalidomide Maintenance for High-Risk Multiple Myeloma after Allogeneic Hematopoietic Cell Transplantation
ASBMT Biology of Blood and Marrow Transplantation, August 2014


Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition
Drug Metabolism Reviews, August 2014


Outpatient bendamustine and idarubicin for upfront therapy of elderly acute myeloid leukaemia/myelodysplastic syndrome: a phase I/II study using an innovative statistical design
British Journal of Haematology, August 2014

Syngeneic myoblast transplantation improves muscle function in a murine model of X-linked myotubular myopathy
Cell Transplantation, August 2014

User-guided segmentation for volumetric retinal optical coherence tomography images
Journal of Biomedical Optics, August 2014


Cardiac regeneration using pluripotent stem cells-Progression to large animal models
Stem Cell Research, July 2014


Cell-based delivery of dATP via gap junctions enhances cardiac contractility
Journal of Molecular and Cellular Cardiology, July 2014


Control of Insulin Secretion by Cytochrome c and Calcium Signaling in Islets with Impaired Metabolism
The Journal of Biological Chemistry, July 2014


Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice
Mammalian Genome, July 2014


Genomic DNA Recombination with Cell-Penetrating Peptide-Tagged Cre Protein in Mouse Skeletal and Cardiac Muscle
Genesis, July 2014

Inferring Clonal Composition from Multiple Sections of a Breast Cancer
PLOS ONE, July 2014


Introduction to JCPT Focused Issue on ‘‘Stem Cells and Cardiac Regenerative Medicine’’
Journal of Cardiovascular Pharmacology and Therapeutics, July 2014


Macrophages modulate adult zebrafish tail fin regeneration
Development, July 2014


Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias
The FASEB Journal, July 2014

Naive embryonic stem cells: the future of stem cell research?
Regenerative Medicine, July 2014


Recent advances in imaging-guided interventions for prostate cancers
Cancer Letters, July 2014


Thin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts
Journal of Molecular and Cellular Cardiology, July 2014


Tri-iodo- L-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells
Journal of Molecular and Cellular Cardiology, July 2014


WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors
The Journal of Clinical Investigation, July 2014


Biophysical and biomechanical properties of myofilament proteins
Archives of Biochemistry and Biophysics, June 2014


Enhanced Chondrogenic Differentiation of Dental Pulp Stem Cells Using Nanopatterned PEG-GelMA-HA Hydrogels
Tissue Engineering: Part A, June 2014


Evidence for lysine 1 acetylation in the coat protein of a Polerovirus
Journal of General Virology, June 2014


Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
Nature, June 2014


Intense and Specialized Dendritic Localization of the Fragile X Mental Retardation Protein in Binaural Brainstem Neurons: A Comparative Study in the Alligator, Chicken, Gerbil, and Human
The Journal of Comparative Neurology, June 2014


Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
Nature Medicine, June 2014


The past, present, and future of retinal regeneration
Experimental Eye Research, June 2014


Varying Correlation Between 18F-Fluorodeoxyglucose Positron Emission Tomography and Dynamic Contrast- Enhanced MRI in Carotid Atherosclerosis: Implications for Plaque Inflammation
Stroke, June 2014


Hypoxia-Inducible Factors Have Distinct and Stage-Specific Roles during Reprogramming of Human Cells to Pluripotency
Cell Stem Cell, May 2014


Methylation of Twelve CpGs in Human Papillomavirus Type 16 (HPV16) as an Informative Biomarker for the Triage of Women Positive for HPV16 Infection
Cancer Prevention Research, May 2014


miRNA sensitivity to Drosha levels correlates with pre-miRNA secondary structure
RNA, May 2014


Proliferation at the Heart of Preadolescence
Cell, May 2014


Retinal Neovascularization and Endogenous Fungal Endophthalmitis in Intravenous Drug Users
Ophthalmology, May 2014


THY-1 Receptor Expression Differentiates Cardiosphere-Derived Cells with Divergent Cardiogenic Differentiation Potential
Stem Cell Reports, May 2014


Ultrasound Assessment of the Diaphragm: Preliminary Study of a Canine Model of X-Linked Myotubular Myopathy
Muscle & Nerve, May 2014


Assessment of Heart Microstructure: From Mouse to Man
Circulation, April 2014


Hemangiopericytoma: Radical resection remains the cornerstone of therapy
Journal of Clinical Neuroscience, April 2014


Derivation of naïve human embryonic stem cells
PNAS, March 2014