Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

A functionalized, injectable hydrogel for localized drug delivery with tunable thermosensitivity: Synthesis and characterization of physical and toxicological properties
Journal of Controlled Release, June 2015

Biomimetic 3D Tissue Models for Advanced High-Throughput Drug Screening
Journal of Laboratory Automation, June 2015


Guanidinylated block copolymers for gene transfer: A comparison with amine-based materials for in vitro and in vivo gene transfer efficiency
Biomaterials, June 2015

Idarubicin, cytarabine, and pravastatin as induction therapy for untreated acute myeloid leukemia and high-risk myelodysplastic syndrome
American Journal of Hematology, June 2015

Interventional MRI-guided local delivery of agents into swine bile duct walls using MR-compatible needle-integrated balloon catheter system
NMR in Biomedicine, June 2015


Multicontrast high-resolution vessel wall magnetic resonance imaging and its value in differentiating intracranial vasculopathic processes
Stroke, June 2015


O6-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
BBA Clinical, June 2015

The embryonic myosin R672C mutation that underlies Freeman-Sheldon syndrome impairs cross-bridge detachment and cycling in adult skeletal muscle
Human Molecular Genetics, June 2015


A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels
Nature Materials, May 2015


Ascending KLFs in cardiovascular biology
Trends in Cardiovascular Medicine, May 2015


Cardiac Development in Zebrafish and Human Embryonic Stem Cells Is Inhibited by Exposure to Tobacco Cigarettes and E-Cigarettes
PLOS ONE, May 2015


Dual energy computed tomography quantification of carotid plaques calcification: comparison between monochromatic and polychromatic energies with pathology correlation
European Radiology, May 2015

Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells
The Journal of Clinical Investigation, May 2015


Identification of a prg4-expressing articular cartilage progenitor cell population in mice
Arthritis & Rheumatology, May 2015


Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes
PNAS, May 2015


Multivalent display of pendant pro-apoptotic peptides increases cytotoxic activity
Journal of Controlled Release, May 2015


Outcomes after stent graft therapy for dissection-related aneurysmal degeneration in the descending thoracic aorta
Journal of Vascular Surgery, May 2015


The winding road to regenerating the human heart
Cardiovascular Pathology, May-June 2015


Tie-mediated signal from apoptotic cells protects stem cells in Drosophila melanogaster
                 Nature Communications, May 2015


G-CSF Priming, clofarabine, and high dose cytarabine (GCLAC) for upfront treatment of acute myeloid leukemia, advanced myelodysplastic syndrome or advanced myeloproliferative neoplasm
                 American Journal of Hematology, April 2015

JALA Special Issue: Microengineered Cell- and Tissue-Based Assays for Drug Screening and Toxicology Applications
Journal of Laboratory Automation, April 2015


LINGO-1 Protein Interacts with the p75 Neurotrophin Receptor in Intracellular Membrane Compartments
The Journal of Biological Chemistry, April 2015


Mechanisms of Bone Marrow−Derived Cell Therapy in Ischemic Cardiomyopathy With Left Ventricular Assist Device Bridge to Transplant
Journal of the American College of Cardiology, April 2015


Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain
Archives of Biochemistry and Biophysics, April 2015


Probing the Protein Interaction Network of Pseudomonas aeruginosa Cells by Chemical Cross-Linking Mass Spectrometry
Structure, April 2015


Relation of Clinical Response and Minimal Residual Disease and Their Prognostic Impact on Outcome in Acute Myeloid Leukemia
Journal of Clinical Oncology, April 2015


The mitochondrial permeability transition pore regulates endothelial bioenergetics and angiogenesis
Circulation Research, April 2015


The proteomic landscape of triple-negative breast cancer
Cell Reports, April 2015