ARRA Latent TB Detection and Implications in HIV-1 Infected Women and Their Children

Funding: NIH 3R21 HD058477-02S1

PI: Grace John-Stewart

Funding period: 09/01/10-08/31/12 (No Cost Extension)

This administrative supplement aims to accelerate our ongoing research activities by increasing our analytical capacity and by expanding assessment of the sensitivity, specificity, predictive value, and correlates of mycobacterium tuberculosis (MTB)-specific interferon-gamma release assays (IGRAs) for detection of latent TB infection (LTBI) in HIV-1 infected women and their children.

This study will evaluate prevalence, correlates and implications of LTBI as determined by immunodiagnostic assays in a cohort of HIV-1 infected women and their children.

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