Cervical Dysplasia in HIV-Positive Women on Anti-Retroviral Therapy in Kenya

PI: Michael Chung
The study is a retrospective analysis of data from the first year of the Coptic Hope Center (Nairobi, Kenya) cervical cancer screening program from July 2006 to June 2007. The purpose of this analysis is to examine the outcomes of the program including the acceptability of Pap smears and barriers to receiving screening in this population, the epidemiology of cervical disease in this group of HIV-positive patients, and characteristics of subjects that may have played a role in the development of cervical lesions. Over the study period, 595 subjects were offered Pap smears. The inclusion criteria included HIV-infected women with intact cervixes between the ages of 30 and 39 and on antiretroviral medications. Slides were read by an on-site pathologist and subjects who were found to have a high-grade lesion were referred to Kenyatta National Hospital (KNH) for follow-up care. Chart reviews were conducted at both the Hope Center and KNH.


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